Synthesis of methoxy-substituted chalcones and in vitro evaluation of their anticancer potential

Chemical Biology and Drug Design

Volumn 82, Issue 6, 2013, Pages 732-742

  Ethiraj, Kannatt Radhakrishnan ^a   Aranjani, Jesil Mathew ^b   Khan, Fazlur Rahman Nawaz ^a  

^a VIT UNIVERSITY   (India)

^b MANIPAL COLLEGE OF PHARMACEUTICAL SCIENCES   (India)

Author keywords

Apoptosis; Chalcones; Chromatin condensation; Cytotoxicity; DNA damage; Flow cytometry

Indexed keywords

3 (2,3,4 TRIMETHOXYPHENYL) 1 (2 NAPHTHYL)PROP 2 EN 1 ONE; 3 (2,4 DIMETHOXYPHENYL) 1 (2 NAPHTHYL)PROP 2 EN 1 ONE; 3 (2,4,6 TRIMETHOXYPHENYL) 1 (2 NAPHTHYL)PROP 2 EN 1 ONE; 3 (2,5 DIMETHOXYPHENYL) 1 (2 NAPHTHYL)PROP 2 EN 1 ONE; 3 (3,4,5 TRIMETHOXYPHENYL) 1 (2 NAPHTHYL)PROP 2 EN 1 ONE; 3 (3,5 DIMETHOXYPHENYL) 1 (2 NAPHTHYL)PROP 2 EN 1 ONE; ANTINEOPLASTIC AGENT; CHALCONE DERIVATIVE; CISPLATIN; DOXORUBICIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CYTOTOXICITY; DRUG SYNTHESIS; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; PRIORITY JOURNAL; SUBSTITUTION REACTION;

APOPTOSIS; CHALCONES; CHROMATIN CONDENSATION; CYTOTOXICITY; DNA DAMAGE; FLOW CYTOMETRY;

ALDEHYDES; ANTINEOPLASTIC AGENTS; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL SURVIVAL; CHALCONES; CHROMATIN; DNA BREAKS, DOUBLE-STRANDED; HELA CELLS; HUMANS; NAPHTHALENES;

EID: 84889770138     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/cbdd.12184     Document Type: Article

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