-
1
-
-
84954971084
-
Sensitization to horse serum by means of adjuvants
-
Freund J, McDermott K. Sensitization to horse serum by means of adjuvants. Proc Soc Exp Biol Med. 1942;49:548-553.
-
(1942)
Proc Soc Exp Biol Med
, vol.49
, pp. 548-553
-
-
Freund, J.1
McDermott, K.2
-
2
-
-
0034886143
-
Toll-like receptors: Critical proteins linking innate and acquired immunity
-
Akira S, Takeda K, Kaisho T. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat Immunol. 2001;2:675-680.
-
(2001)
Nat Immunol
, vol.2
, pp. 675-680
-
-
Akira, S.1
Takeda, K.2
Kaisho, T.3
-
3
-
-
0037018097
-
Adjuvants of immunity: Harnessing innate immunity to promote adaptive immunity
-
Bendelac A, Medzhitov R. Adjuvants of immunity: harnessing innate immunity to promote adaptive immunity. J Exp Med. 2002;195:F19-F23.
-
(2002)
J Exp Med
, vol.195
-
-
Bendelac, A.1
Medzhitov, R.2
-
4
-
-
0036219195
-
CpG motifs in bacterial DNA and their immune effects
-
Krieg AM. CpG motifs in bacterial DNA and their immune effects. Annu Rev Immunol. 2002;20:709-760.
-
(2002)
Annu Rev Immunol
, vol.20
, pp. 709-760
-
-
Krieg, A.M.1
-
5
-
-
0037083664
-
CpG oligodeoxynucleotides as vaccine adjuvants in primates
-
Verthelyi D, Kenney RT, Seder RA, et al. CpG oligodeoxynucleotides as vaccine adjuvants in primates. J Immunol. 2002;168:1659-1663.
-
(2002)
J Immunol
, vol.168
, pp. 1659-1663
-
-
Verthelyi, D.1
Kenney, R.T.2
Seder, R.A.3
-
6
-
-
0036467426
-
CpG are efficient adjuvants for specific CTL induction against tumor antigen-derived peptide
-
Miconnet I, Koenig S, Speiser D, et al. CpG are efficient adjuvants for specific CTL induction against tumor antigen-derived peptide. J Immunol. 2002;168:1212-1218.
-
(2002)
J Immunol
, vol.168
, pp. 1212-1218
-
-
Miconnet, I.1
Koenig, S.2
Speiser, D.3
-
7
-
-
0034163408
-
CpG-DNA activates in vivo T cell epitope presenting dendritic cells to trigger protective antiviral cytotoxic T cell responses
-
Vabulas RM, Pircher H, Lipford GB, Hacker H, Wagner H. CpG-DNA activates in vivo T cell epitope presenting dendritic cells to trigger protective antiviral cytotoxic T cell responses. J Immunol. 2000;164:2372-2378.
-
(2000)
J Immunol
, vol.164
, pp. 2372-2378
-
-
Vabulas, R.M.1
Pircher, H.2
Lipford, G.B.3
Hacker, H.4
Wagner, H.5
-
8
-
-
0034235701
-
Repeated administration of cytosine-phosphorothiolated guanine-containing oligonucleotides together with peptide/protein immunization results in enhanced CTL responses with anti-tumor activity
-
Davila E, Celis E. Repeated administration of cytosine-phosphorothiolated guanine-containing oligonucleotides together with peptide/protein immunization results in enhanced CTL responses with anti-tumor activity. J Immunol. 2000;165:539-547.
-
(2000)
J Immunol
, vol.165
, pp. 539-547
-
-
Davila, E.1
Celis, E.2
-
9
-
-
0036785631
-
Peritumoral CpG DNA elicits a coordinated response of CD8 T cells and innate effectors to cure established tumors in a murine colon carcinoma model
-
Heckelsmiller K, Rall K, Beck S, et al. Peritumoral CpG DNA elicits a coordinated response of CD8 T cells and innate effectors to cure established tumors in a murine colon carcinoma model. J Immunol. 2002;169:3892-3899.
-
(2002)
J Immunol
, vol.169
, pp. 3892-3899
-
-
Heckelsmiller, K.1
Rall, K.2
Beck, S.3
-
10
-
-
0036857655
-
Combined dendritic cell- and CpG oligonucleotide-based immune therapy cures large murine tumors that resist chemotherapy
-
Heckelsmiller K, Beck S, Rall K, et al. Combined dendritic cell- and CpG oligonucleotide-based immune therapy cures large murine tumors that resist chemotherapy. Eur J Immunol. 2002;32:3235-3245.
-
(2002)
Eur J Immunol
, vol.32
, pp. 3235-3245
-
-
Heckelsmiller, K.1
Beck, S.2
Rall, K.3
-
11
-
-
0034650517
-
Mechanism and function of a newly identified CpG DNA motif in human primary B cells
-
Hartmann G, Krieg AM. Mechanism and function of a newly identified CpG DNA motif in human primary B cells. J Immunol. 2000;164:944-953.
-
(2000)
J Immunol
, vol.164
, pp. 944-953
-
-
Hartmann, G.1
Krieg, A.M.2
-
12
-
-
0034142182
-
Delineation of a CpG phosphorothioate oligodeoxynucleotide for activating primate immune responses in vitro and in vivo
-
Hartmann G, Weeratna RD, Ballas ZK, et al. Delineation of a CpG phosphorothioate oligodeoxynucleotide for activating primate immune responses in vitro and in vivo. J Immunol. 2000;164:1617-1624.
-
(2000)
J Immunol
, vol.164
, pp. 1617-1624
-
-
Hartmann, G.1
Weeratna, R.D.2
Ballas, Z.K.3
-
13
-
-
0035979192
-
Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition
-
Bauer S, Kirschning CJ, Hacker H, et al. Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition. Proc Natl Acad Sci U S A. 2001;98:9237-9242.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 9237-9242
-
-
Bauer, S.1
Kirschning, C.J.2
Hacker, H.3
-
14
-
-
0036570169
-
Quantitative expression of TLR1-10 mRNA in cellular subsets of human PBMC and sensitivity to CpG ODN
-
Hornung V, Rothenfusser S, Britsch S, et al. Quantitative expression of TLR1-10 mRNA in cellular subsets of human PBMC and sensitivity to CpG ODN. J Immunol. 2002;168:4531-4537.
-
(2002)
J Immunol
, vol.168
, pp. 4531-4537
-
-
Hornung, V.1
Rothenfusser, S.2
Britsch, S.3
-
16
-
-
0031867535
-
Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells
-
Sparwasser T, Koch ES, Vabulas RM, et al. Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells. Eur J Immunol. 1998;28:2045-2054.
-
(1998)
Eur J Immunol
, vol.28
, pp. 2045-2054
-
-
Sparwasser, T.1
Koch, E.S.2
Vabulas, R.M.3
-
17
-
-
0034698739
-
Immune cell activation by bacterial CpG-DNA through myeloid differentiation marker 88 and tumor necrosis factor receptor-associated factor (TRAF)6
-
Hacker H, Vabulas RM, Takeuchi O, et al. Immune cell activation by bacterial CpG-DNA through myeloid differentiation marker 88 and tumor necrosis factor receptor-associated factor (TRAF)6. J Exp Med. 2000;192:595-600.
-
(2000)
J Exp Med
, vol.192
, pp. 595-600
-
-
Hacker, H.1
Vabulas, R.M.2
Takeuchi, O.3
-
18
-
-
0034933019
-
Identification of CpG oligonucleotide sequences with high induction of IFN-alpha/beta in plasmacytoid dendritic cells
-
Krug A, Rothenfusser S, Hornung V, et al. Identification of CpG oligonucleotide sequences with high induction of IFN-alpha/beta in plasmacytoid dendritic cells. Eur J Immunol. 2001;31:2154-2163.
-
(2001)
Eur J Immunol
, vol.31
, pp. 2154-2163
-
-
Krug, A.1
Rothenfusser, S.2
Hornung, V.3
-
20
-
-
0035865054
-
Human peripheral blood cells differentially recognize and respond to two distinct CPG motifs
-
Verthelyi D, Ishii K, Gursel M, Takeshita F, Klinman D. Human peripheral blood cells differentially recognize and respond to two distinct CPG motifs. J Immunol. 2001;166:2372-2377.
-
(2001)
J Immunol
, vol.166
, pp. 2372-2377
-
-
Verthelyi, D.1
Ishii, K.2
Gursel, M.3
Takeshita, F.4
Klinman, D.5
-
21
-
-
0035660704
-
Distinct CpG oligonucleoticle sequences activate human gamma delta T cells via interferon-alpha/beta
-
Rothenfusser S, Hornung V, Krug A, et al. Distinct CpG oligonucleoticle sequences activate human gamma delta T cells via interferon-alpha/beta. Eur J Immunol. 2001;31:3525-3534.
-
(2001)
Eur J Immunol
, vol.31
, pp. 3525-3534
-
-
Rothenfusser, S.1
Hornung, V.2
Krug, A.3
-
22
-
-
0030239828
-
Induction of NK activity in murine and human cells by CpG motifs in oligodeoxynucleotides and bacterial DNA
-
Ballas ZK, Rasmussen WL, Krieg AM. Induction of NK activity in murine and human cells by CpG motifs in oligodeoxynucleotides and bacterial DNA. J Immunol. 1996;157:1840-1845.
-
(1996)
J Immunol
, vol.157
, pp. 1840-1845
-
-
Ballas, Z.K.1
Rasmussen, W.L.2
Krieg, A.M.3
-
23
-
-
0032520084
-
Enhanced generation of specific tumor-reactive CTL in vitro by selected Melan-A/MART-1 immunodominant peptide analogues
-
Valmori D, Fonteneau JF, Lizana CM, et al. Enhanced generation of specific tumor-reactive CTL in vitro by selected Melan-A/MART-1 immunodominant peptide analogues. J Immunol. 1998;160:1750-1758.
-
(1998)
J Immunol
, vol.160
, pp. 1750-1758
-
-
Valmori, D.1
Fonteneau, J.F.2
Lizana, C.M.3
-
24
-
-
0029743737
-
Phenotypic analysis of antigen-specific T lymphocytes
-
Altman JD, Moss PAH, Goulder PJR, et al. Phenotypic analysis of antigen-specific T lymphocytes. Science. 1996;274:94-96.
-
(1996)
Science
, vol.274
, pp. 94-96
-
-
Altman, J.D.1
Moss, P.A.H.2
Goulder, P.J.R.3
-
25
-
-
0031283081
-
Control of B cell lymphoma recognition via natural killer inhibitory receptors implies a role for human V-γ/9/Vδ2 T cells in tumor immunity
-
Fisch P, Meuer E, Pende D, et al. Control of B cell lymphoma recognition via natural killer inhibitory receptors implies a role for human V-γ/9/Vδ2 T cells in tumor immunity. Eur J Immunol. 1997;27:3368-3379.
-
(1997)
Eur J Immunol
, vol.27
, pp. 3368-3379
-
-
Fisch, P.1
Meuer, E.2
Pende, D.3
-
26
-
-
0032819985
-
High frequencies of naive Melan-A/MART-1-specific CD8(+) T cells in a large proportion of human histocompatibility leukocyte antigen (HLA)-A2 individuals
-
Pittet MJ, Valmori D, Dunbar PR, et al. High frequencies of naive Melan-A/MART-1-specific CD8(+) T cells in a large proportion of human histocompatibility leukocyte antigen (HLA)-A2 individuals. J Exp Med. 1999;190:705-715.
-
(1999)
J Exp Med
, vol.190
, pp. 705-715
-
-
Pittet, M.J.1
Valmori, D.2
Dunbar, P.R.3
-
27
-
-
0037128179
-
Thymic selection generates a large T cell pool recognizing a self-peptide in humans
-
Zippelius A, Pittet MJ, Batard P, et al. Thymic selection generates a large T cell pool recognizing a self-peptide in humans. J Exp Med. 2002;195:485-494.
-
(2002)
J Exp Med
, vol.195
, pp. 485-494
-
-
Zippelius, A.1
Pittet, M.J.2
Batard, P.3
-
28
-
-
0034777579
-
Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12
-
Krug A, Towarowski A, Britsch S, et al. Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12. Eur J Immunol. 2001;31:3026-3037.
-
(2001)
Eur J Immunol
, vol.31
, pp. 3026-3037
-
-
Krug, A.1
Towarowski, A.2
Britsch, S.3
-
29
-
-
0033056073
-
Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients
-
Lee PP, Yee C, Savage PA, et al. Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients. Nat Med. 1999;5:677-685.
-
(1999)
Nat Med
, vol.5
, pp. 677-685
-
-
Lee, P.P.1
Yee, C.2
Savage, P.A.3
-
30
-
-
0037139370
-
Peptide-specific CD8+ T-cell evolution in vivo: Response to peptide vaccination with Melan-A/MART-1
-
Jager E, Hohn H, Necker A, et al. Peptide-specific CD8+ T-cell evolution in vivo: response to peptide vaccination with Melan-A/MART-1. Int J Cancer. 2002;98:376-388.
-
(2002)
Int J Cancer
, vol.98
, pp. 376-388
-
-
Jager, E.1
Hohn, H.2
Necker, A.3
-
31
-
-
0027252136
-
CD28 T lymphocytes: Antigenic and functional properties
-
Azuma M, Phillips JH, Lanier LL. CD28 T lymphocytes: antigenic and functional properties. J Immunol. 1993;150:1147-1159.
-
(1993)
J Immunol
, vol.150
, pp. 1147-1159
-
-
Azuma, M.1
Phillips, J.H.2
Lanier, L.L.3
-
32
-
-
0029043647
-
A novel receptor involved in T-cell activation
-
Cocks BG, Chang CC, Carballido JM, et al. A novel receptor involved in T-cell activation. Nature. 1995;376:260-263.
-
(1995)
Nature
, vol.376
, pp. 260-263
-
-
Cocks, B.G.1
Chang, C.C.2
Carballido, J.M.3
-
33
-
-
0034141830
-
Cutting edge: Cytolytic effector function in human circulating CD8+ T cells closely correlates with CD56 surface expression
-
Pittet MJ, Speiser DE, Valmori D, Cerottini JC, Romero P. Cutting edge: cytolytic effector function in human circulating CD8+ T cells closely correlates with CD56 surface expression. J Immunol. 2000;164:1148-1152.
-
(2000)
J Immunol
, vol.164
, pp. 1148-1152
-
-
Pittet, M.J.1
Speiser, D.E.2
Valmori, D.3
Cerottini, J.C.4
Romero, P.5
-
34
-
-
0033009888
-
Natural killer cells in antiviral defense: Function and regulation by innate cytokines
-
Biron CA, Nguyen KB, Pien GC, Cousens LP, Salazar-Mather TP. Natural killer cells in antiviral defense: function and regulation by innate cytokines. Annu Rev Immunol. 1999;17:189-220.
-
(1999)
Annu Rev Immunol
, vol.17
, pp. 189-220
-
-
Biron, C.A.1
Nguyen, K.B.2
Pien, G.C.3
Cousens, L.P.4
Salazar-Mather, T.P.5
-
35
-
-
0034954034
-
Interferons alpha and beta as immune regulators-a new look
-
Biron CA. Interferons alpha and beta as immune regulators-a new look. Immunity. 2001;14:661-664.
-
(2001)
Immunity
, vol.14
, pp. 661-664
-
-
Biron, C.A.1
-
36
-
-
18744373312
-
Antigenicity and immunogenicity of Melan-A/MART-1 derived peptides as targets for tumor reactive CTL in human melanoma
-
Romero P, Valmori D, Pittet MJ, et al. Antigenicity and immunogenicity of Melan-A/MART-1 derived peptides as targets for tumor reactive CTL in human melanoma. Immunol Rev. 2002;188:81-96.
-
(2002)
Immunol Rev
, vol.188
, pp. 81-96
-
-
Romero, P.1
Valmori, D.2
Pittet, M.J.3
-
37
-
-
0027536244
-
B lymphocytes in vivo fail to prime naive T cells but can stimulate antigen-experienced T lymphocytes
-
Ronchese F, Hausmann B. B lymphocytes in vivo fail to prime naive T cells but can stimulate antigen-experienced T lymphocytes. J Exp Med. 1993;177:679-690.
-
(1993)
J Exp Med
, vol.177
, pp. 679-690
-
-
Ronchese, F.1
Hausmann, B.2
-
38
-
-
0026451165
-
B cells turn off virgin but not memory T cells
-
Fuchs EJ, Matzinger P. B cells turn off virgin but not memory T cells. Science. 1992;258:1156-1159.
-
(1992)
Science
, vol.258
, pp. 1156-1159
-
-
Fuchs, E.J.1
Matzinger, P.2
-
39
-
-
0029091255
-
Successful T cell priming in B cell-deficient mice
-
Epstein MM, Di Rosa F, Jankovic D, Sher A, Matzinger P. Successful T cell priming in B cell-deficient mice. J Exp Med. 1995;182:915-922.
-
(1995)
J Exp Med
, vol.182
, pp. 915-922
-
-
Epstein, M.M.1
Di Rosa, F.2
Jankovic, D.3
Sher, A.4
Matzinger, P.5
-
40
-
-
0027254491
-
CD4+ and B lymphocytes in transplantation immunity, II: Augmented rejection of tumor allografts by mice lacking B cells
-
Monach PA, Schreiber H, Rowley DA. CD4+ and B lymphocytes in transplantation immunity, II: augmented rejection of tumor allografts by mice lacking B cells. Transplantation. 1993;55:1356-1361.
-
(1993)
Transplantation
, vol.55
, pp. 1356-1361
-
-
Monach, P.A.1
Schreiber, H.2
Rowley, D.A.3
-
41
-
-
0031863680
-
B cells inhibit induction of T cell-dependent tumor immunity
-
Qin Z, Richter G, Schuler T, et al. B cells inhibit induction of T cell-dependent tumor immunity. Nat Med. 1998;4:627-630.
-
(1998)
Nat Med
, vol.4
, pp. 627-630
-
-
Qin, Z.1
Richter, G.2
Schuler, T.3
-
43
-
-
0032433054
-
Type I interferon-mediated stimulation of T cells by CpG DNA
-
Sun S, Zhang X, Tough DF, Sprent J. Type I interferon-mediated stimulation of T cells by CpG DNA. J Exp Med. 1998;188:2335-2342.
-
(1998)
J Exp Med
, vol.188
, pp. 2335-2342
-
-
Sun, S.1
Zhang, X.2
Tough, D.F.3
Sprent, J.4
-
44
-
-
0033731162
-
Multiple effects of immunostimulatory DNA on T cells and the role of type I interferons
-
Sun S, Zhang X, Tough D, Sprent J. Multiple effects of immunostimulatory DNA on T cells and the role of type I interferons. Springer Semin Immunopathol. 2000;22:77-84.
-
(2000)
Springer Semin Immunopathol
, vol.22
, pp. 77-84
-
-
Sun, S.1
Zhang, X.2
Tough, D.3
Sprent, J.4
-
45
-
-
0030036342
-
Induction of bystander T cell proliferation by viruses and type I interferon in vivo
-
Tough DF, Borrow P, Sprent J. Induction of bystander T cell proliferation by viruses and type I interferon in vivo. Science. 1996;272:1947-1950.
-
(1996)
Science
, vol.272
, pp. 1947-1950
-
-
Tough, D.F.1
Borrow, P.2
Sprent, J.3
-
46
-
-
0033081259
-
Type I interferons keep activated T cells alive
-
Marrack P, Kappler J, Mitchell T. Type I interferons keep activated T cells alive. J Exp Med. 1999;189:521-530.
-
(1999)
J Exp Med
, vol.189
, pp. 521-530
-
-
Marrack, P.1
Kappler, J.2
Mitchell, T.3
-
47
-
-
0032076635
-
Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15
-
Zhang X, Sun S, Hwang I, Tough DF, Sprent J. Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15. Immunity. 1998;8:591-599.
-
(1998)
Immunity
, vol.8
, pp. 591-599
-
-
Zhang, X.1
Sun, S.2
Hwang, I.3
Tough, D.F.4
Sprent, J.5
-
48
-
-
0036467552
-
Overexpression of IL-15 in vivo increases antigen-driven memory CD8+ T cells following a microbe exposure
-
Yajima T, Nishimura H, Ishimitsu R, et al. Overexpression of IL-15 in vivo increases antigen-driven memory CD8+ T cells following a microbe exposure. J Immunol. 2002;168:1198-1203.
-
(2002)
J Immunol
, vol.168
, pp. 1198-1203
-
-
Yajima, T.1
Nishimura, H.2
Ishimitsu, R.3
-
49
-
-
0037377990
-
CpG-A ODN induce a monocyte-derived dendritic cell-like phenotype which preferentially activates CD8 T cells
-
Krug A, Rothenfusser S, Selinger S, et al. CpG-A ODN induce a monocyte-derived dendritic cell-like phenotype which preferentially activates CD8 T cells. J Immunol. 2003;170:3468-3477.
-
(2003)
J Immunol
, vol.170
, pp. 3468-3477
-
-
Krug, A.1
Rothenfusser, S.2
Selinger, S.3
-
50
-
-
0032812664
-
Interferon-alpha inhibits proliferation in human T lymphocytes by abrogation of interleukin 2-induced changes in cell cycle-regulatory proteins
-
Erickson S, Sangfelt O, Castro J, et al. Interferon-alpha inhibits proliferation in human T lymphocytes by abrogation of interleukin 2-induced changes in cell cycle-regulatory proteins. Cell Growth Differ. 1999;10:575-582.
-
(1999)
Cell Growth Differ
, vol.10
, pp. 575-582
-
-
Erickson, S.1
Sangfelt, O.2
Castro, J.3
-
51
-
-
0034944385
-
Type I interferons and IL-12: Convergence and cross-regulation among mediators of cellular immunity
-
Byrnes AA, Ma X, Cuomo P, et al. Type I interferons and IL-12: convergence and cross-regulation among mediators of cellular immunity. Eur J Immunol. 2001;31:2026-2034.
-
(2001)
Eur J Immunol
, vol.31
, pp. 2026-2034
-
-
Byrnes, A.A.1
Ma, X.2
Cuomo, P.3
-
52
-
-
0033961721
-
IFN-beta differentially regulates CD40-induced cytokine secretion by human dendritic cells
-
McRae BL, Beilfuss BA, van Seventer GA. IFN-beta differentially regulates CD40-induced cytokine secretion by human dendritic cells. J Immunol. 2000;164:23-28.
-
(2000)
J Immunol
, vol.164
, pp. 23-28
-
-
McRae, B.L.1
Beilfuss, B.A.2
Van Seventer, G.A.3
-
53
-
-
0038683055
-
Phase 1/11 study with 7909 as adjuvant to vaccination with Mage-3 protein in patients with Mage-3 positive tumors
-
van Ojik H, Kruit W, Portielje J, et al. Phase 1/11 study with 7909 as adjuvant to vaccination with Mage-3 protein in patients with Mage-3 positive tumors [abstract]. Ann Oncol. 2003;13:157.
-
(2003)
Ann Oncol
, vol.13
, pp. 157
-
-
Van Ojik, H.1
Kruit, W.2
Portielje, J.3
|