Erratum: Caspase-2 deficiency promotes aberrant DNA-damage response and genetic instability (Cell Death and Differentiation (2012) 19 (1288-1298) DOI: 10.1038/cdd.2012.36);Caspase-2 deficiency promotes aberrant DNA-damage response and genetic instability

Cell Death and Differentiation

Volumn 19, Issue 8, 2012, Pages 1288-1298

  Dorstyn, L ^a,b   Puccini, J ^a,b   Wilson, C H ^a   Shalini, S ^a   Nicola, M ^c   Moore, S ^c   Kumar, S ^a,b  

^a INSTITUTE OF MEDICAL AND VETERINARY SCIENCE   (Australia)

^b UNIVERSITY OF ADELAIDE   (Australia)

^c SA Pathology ^*  (Australia)

Author keywords

caspases; cell cycle; DNA damage response; genomic instability

Indexed keywords

CASPASE 2; PROTEIN P21; PROTEIN P53; TUMOR SUPPRESSOR PROTEIN;

ANEUPLOIDY; ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER CELL; CELL AGING; CELL CYCLE CHECKPOINT; CELL CYCLE REGULATION; CELL PROLIFERATION; CELL TRANSFORMATION; CONTROLLED STUDY; DNA DAMAGE; FIBROBLAST; GAMMA IRRADIATION; GENOMIC INSTABILITY; LYMPHOMA CELL; METAPHASE; MICRONUCLEUS; MOUSE; NONHUMAN; ONCOGENE MYC; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TELOMERE; TRANSACTIVATION;

EID: 84863718495     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2012.76     Document Type: Erratum

References (40)

1. Kumar S, Kinoshita M, Noda M, Copeland NG, Jenkins NA. Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme Genes Dev 1994; 8: 1613-1626. (Pubitemid 24236241)
2. Lassus P, Opitz-Araya X, Lazebnik Y. Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization. Science 2002; 297: 1352-1354. (Pubitemid 34913174)
3. Robertson JD, Enoksson M, Suomela M, Zhivotovsky B, Orrenius S. Caspase-2 acts upstream of mitochondria to promote cytochrome c release during etoposide-induced apoptosis. J Biol Chem 2002; 277: 29803-29809.
4. Bonzon C, Bouchier-Hayes L, Pagliari LJ, Green DR, Newmeyer DD. Caspase-2-induced apoptosis requires bid cleavage: a physiological role for bid in heat shock-induced death. Mol Biol Cell 2006; 17: 2150-2157. (Pubitemid 44011731)
5. Shin S, Lee Y, Kim W, Ko H, Choi H, Kim K. Caspase-2 primes cancer cells for TRAIL-mediated apoptosis by processing procaspase-8. EMBO J 2005; 24: 3532-3542. (Pubitemid 41509361)
6. Ho LH, Read SH, Dorstyn L, Lambrusco L, Kumar S. Caspase-2 is required for cell death induced by cytoskeletal disruption. Oncogene 2008; 27: 3393-3404. (Pubitemid 351769315)
7. Bergeron L, Perez GI, Macdonald G, Shi L, Sun Y, Jurisicova A et al. Defects in regulation of apoptosis in caspase-2-deficient mice. Genes Dev 1998; 12: 1304-1314. (Pubitemid 28213406)
8. Nutt LK, Margolis SS, Jensen M, Herman CE, Dunphy WG, Rathmell JC et al. Metabolic regulation of oocyte cell death through the CaMKII-mediated phosphorylation of caspase-2. Cell 2005; 123: 89-103. (Pubitemid 41414531)
9. O'Reilly LA, Ekert P, Harvey N, Marsden V, Cullen L, Vaux DL et al. Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both Apaf-1 and caspase-9. Cell Death Differ 2002; 9: 832-841.
10. Marsden VS, Ekert PG, Van Delft M, Vaux DL, Adams JM, Strasser A. Bcl-2-regulated apoptosis and cytochrome c release can occur independently of both caspase-2 and caspase-9. J Cell Biol 2004; 165: 775-780. (Pubitemid 38821968)
11. Braga M, Sinha Hikim AP, Datta S, Ferrini MG, Brown D, Kovacheva EL et al. Involvement of oxidative stress and caspase 2-mediated intrinsic pathway signaling in age-related increase in muscle cell apoptosis in mice. Apoptosis 2008; 13: 822-832.
12. Zhang Y, Padalecki SS, Chaudhuri AR, De Waal E, Goins BA, Grubbs B et al. Caspase-2 deficiency enhances aging-related traits in mice. Mech Ageing Dev 2007; 128: 213-221. (Pubitemid 46109019)
13. Shalini S, Dorstyn L, Wilson C, Puccini J, Ho L, Kumar S. Impaired antioxidant defence and accumulation of oxidative stress in caspase-2-deficient mice. Cell Death Differ 2012 e-pub ahead of print 17 February 2012; doi: 10.1038/cdd.2012.13.
14. Baliga BC, Colussi PA, Read SH, Dias MM, Jans DA, Kumar S. Role of prodomain in importin-mediated nuclear localization and activation of caspase-2. J Biol Chem 2003; 278: 4899-4905. (Pubitemid 36800996)
15. Colussi PA, Harvey NL, Kumar S. Prodomain-dependent nuclear localization of the caspase-2 (Nedd2) precursor. A novel function for a caspase prodomain. J Biol Chem 1998; 273: 24535-24542. (Pubitemid 28454949)
16. Kumar S. Caspase 2 in apoptosis, the DNA damage response and tumour suppression: enigma no more? Nat Rev Cancer 2009; 9: 897-903.
17. Ho LH, Taylor R, Dorstyn L, Cakouros D, Bouillet P, Kumar S. A tumor suppressor function for caspase-2. Proc Natl Acad Sci USA 2009; 106: 5336-5341.
18. Sidi S, Sanda T, Kennedy RD, Hagen AT, Jette CA, Hoffmans R et al. Chk1 suppresses a caspase-2 apoptotic response to DNA damage that bypasses p53, Bcl-2, and caspase-3. Cell 2008; 133: 864-877. (Pubitemid 351715394)
19. Carnero A, Hudson JD, Price CM, Beach DH. p16INK4A and p19ARF act in overlapping pathways in cellular immortalization. Nat Cell Biol 2000; 2: 148-155.
20. Harper JW, Elledge SJ. The DNA damage response: ten years after. Mol Cell 2007; 28: 739-745. (Pubitemid 350217064)
21. Tao W, Levine AJ. Nucleocytoplasmic shuttling of oncoprotein Hdm2 is required for Hdm2-mediated degradation of p53. Proc Natl Acad Sci USA 1999; 96: 3077-3080. (Pubitemid 29148846)
22. Tao W, Levine AJ. P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2. Proc Natl Acad Sci USA 1999; 96: 6937-6941. (Pubitemid 29274988)
23. Riley T, Sontag E, Chen P, Levine A. Transcriptional control of human p53-regulated genes. Nat Rev Mol Cell Biol 2008; 9: 402-412. (Pubitemid 351574202)
24. Lavin MF. Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer. Nat Rev Mol Cell Biol 2008; 9: 759-769.
25. Cimprich KA, Cortez D. ATR: an essential regulator of genome integrity. Nat Rev Mol Cell Biol 2008; 9: 616-627. (Pubitemid 352032926)
26. Caldecott KW. Single-strand break repair and genetic disease. Nat Rev Genet 2008; 9: 619-631.
27. Holland AJ, Cleveland DW. Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis. Nat Rev Mol Cell Biol 2009; 10: 478-487.
28. Tomasini R, Mak TW, Melino G. The impact of p53 and p73 on aneuploidy and cancer. Trends Cell Biol 2008; 18: 244-252.
29. Li M, Fang X, Baker DJ, Guo L, Gao X, Wei Z et al. The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis. Proc Natl Acad Sci USA 2010; 107: 14188-14193.
30. Parrinello S, Samper E, Krtolica A, Goldstein J, Melov S, Campisi J. Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts. Nat Cell Biol 2003; 5: 741-747. (Pubitemid 36986782)
31. Bringold F, Serrano M. Tumor suppressors and oncogenes in cellular senescence Exp Gerontol 2000; 35: 317-329. (Pubitemid 30314689)
32. Todaro GJ, Green H. Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines. J Cell Biol 1963; 17: 299-313.
33. Sohn D, Budach W, Janicke RU. Caspase-2 is required for DNA damage-induced expression of the CDK inhibitor p21(WAF1/CIP1). Cell Death Differ 2011; 18: 1664-1674.
34. Taghiyev AF, Rokhlin OW, Glover RB. Caspase-2-based regulation of the androgen receptor and cell cycle in the prostate cancer cell line LNCaP. Genes Cancer 2011; 2: 745-752.
35. Fenech M. Chromosomal biomarkers of genomic instability relevant to cancer Drug Discov Today 2002; 7: 1128-1137. (Pubitemid 35346420)
36. Burma S, Chen BP, Murphy M, Kurimasa A, Chen DJ. ATM phosphorylates histone H2AX in response to DNA double-strand breaks. J Biol Chem 2001; 276: 42462-42467.
37. Gartel AL, Radhakrishnan SK. Lost in transcription: p21 repression, mechanisms, and consequences. Cancer Res 2005; 65: 3980-3985. (Pubitemid 40775632)
38. Keogh MC, Kim JA, Downey M, Fillingham J, Chowdhury D, Harrison JC et al. A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery. Nature 2006; 439: 497-501. (Pubitemid 43152843)
39. Woo RA, Poon RY. Activated oncogenes promote and cooperate with chromosomal instability for neoplastic transformation. Genes Dev 2004; 18: 1317-1330. (Pubitemid 38720599)
40. Oliver TG, Meylan E, Chang GP, Xue W, Burke JR, Humpton TJ et al. Caspase-2-mediated cleavage of Mdm2 creates a p53-induced positive feedback loop. Mol Cell 2011; 43: 57-71.