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Volumn 14, Issue 6, 2013, Pages 12346-12366

Urinary bladder cancer susceptibility markers. What do we know about functional mechanisms?

Author keywords

Bladder cancer; GWAS; Risk variants

Indexed keywords

TUMOR MARKER;

EID: 84889600504     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms140612346     Document Type: Article
Times cited : (32)

References (122)
  • 1
    • 74049103101 scopus 로고    scopus 로고
    • Genome-wide association studies in cancer—Current and future directions
    • Chung, C.C.; Magalhaes, W.C.; Gonzalez-Bosquet, J.; Chanock, S.J. Genome-wide association studies in cancer—Current and future directions. Carcinogenesis 2010, 31, 111–120.
    • (2010) Carcinogenesis , vol.31 , pp. 111-120
    • Chung, C.C.1    Magalhaes, W.C.2    Gonzalez-Bosquet, J.3    Chanock, S.J.4
  • 2
    • 76649114002 scopus 로고    scopus 로고
    • Genome-wide association studies of bladder cancer risk: A field synopsis of progress and potential applications
    • Wu, X.; Hildebrandt, M.A.; Chang, D.W. Genome-wide association studies of bladder cancer risk: A field synopsis of progress and potential applications. Cancer Metastasis Rev. 2009, 28, 269–280.
    • (2009) Cancer Metastasis Rev , vol.28 , pp. 269-280
    • Wu, X.1    Hildebrandt, M.A.2    Chang, D.W.3
  • 6
    • 68949187958 scopus 로고    scopus 로고
    • Genome-wide association studies in bladder cancer: First results and potential relevance
    • Kiemeney, L.A.; Grotenhuis, A.J.; Vermeulen, S.H.; Wu, X. Genome-wide association studies in bladder cancer: First results and potential relevance. Curr. Opin. Urol. 2009, 19, 540–546.
    • (2009) Curr. Opin. Urol , vol.19 , pp. 540-546
    • Kiemeney, L.A.1    Grotenhuis, A.J.2    Vermeulen, S.H.3    Wu, X.4
  • 7
    • 77953619147 scopus 로고    scopus 로고
    • Common predisposition alleles for moderately common cancers: Bladder cancer
    • Kiltie, A.E. Common predisposition alleles for moderately common cancers: Bladder cancer. Curr. Opin. Genet. Dev. 2010, 20, 218–224.
    • (2010) Curr. Opin. Genet. Dev , vol.20 , pp. 218-224
    • Kiltie, A.E.1
  • 8
    • 67349258581 scopus 로고    scopus 로고
    • The present and future burden of urinary bladder cancer in the world
    • Ploeg, M.; Aben, K.K.; Kiemeney, L.A. The present and future burden of urinary bladder cancer in the world. World J. Urol. 2009, 27, 289–293.
    • (2009) World J. Urol , vol.27 , pp. 289-293
    • Ploeg, M.1    Aben, K.K.2    Kiemeney, L.A.3
  • 10
    • 67149084303 scopus 로고    scopus 로고
    • Histological variants of urothelial carcinoma: Diagnostic, therapeutic and prognostic implications
    • Amin, M.B. Histological variants of urothelial carcinoma: Diagnostic, therapeutic and prognostic implications. Mod. Pathol. 2009, 22, S96–S118.
    • (2009) Mod. Pathol , vol.22 , pp. S96-S118
    • Amin, M.B.1
  • 11
    • 79955593955 scopus 로고    scopus 로고
    • European Association of, U. EAU guidelines on non-muscle-invasive urothelial carcinoma of the bladder, the 2011 update
    • Babjuk, M.; Oosterlinck, W.; Sylvester, R.; Kaasinen, E.; Bohle, A.; Palou-Redorta, J.; Roupret, M.; European Association of, U. EAU guidelines on non-muscle-invasive urothelial carcinoma of the bladder, the 2011 update. Eur. Urol. 2011, 59, 997–1008.
    • (2011) Eur. Urol , vol.59 , pp. 997-1008
    • Babjuk, M.1    Oosterlinck, W.2    Sylvester, R.3    Kaasinen, E.4    Bohle, A.5    Palou-Redorta, J.6    Roupret, M.7
  • 12
    • 79960992110 scopus 로고    scopus 로고
    • Long-term cancer-specific survival in patients with high-risk, non-muscle-invasive bladder cancer and tumour progression: A systematic review
    • Van den Bosch, S.; Alfred Witjes, J. Long-term cancer-specific survival in patients with high-risk, non-muscle-invasive bladder cancer and tumour progression: A systematic review. Eur. Urol. 2011, 60, 493–500.
    • (2011) Eur. Urol , vol.60 , pp. 493-500
    • Van den Bosch, S.1    Alfred Witjes, J.2
  • 13
    • 33748743092 scopus 로고    scopus 로고
    • Neo-adjuvant chemotherapy for muscle-invasive bladder cancer: A look ahead
    • Sawhney, R.; Bourgeois, D.; Chaudhary, U.B. Neo-adjuvant chemotherapy for muscle-invasive bladder cancer: A look ahead. Ann. Oncol. 2006, 17, 1360–1369.
    • (2006) Ann. Oncol , vol.17 , pp. 1360-1369
    • Sawhney, R.1    Bourgeois, D.2    Chaudhary, U.B.3
  • 14
    • 34548314227 scopus 로고    scopus 로고
    • The value of bladder-conserving strategies in muscle-invasive bladder carcinoma compared with radical surgery
    • Merseburger, A.S.; Kuczyk, M.A. The value of bladder-conserving strategies in muscle-invasive bladder carcinoma compared with radical surgery. Curr. Opin. Urol. 2007, 17, 358–362.
    • (2007) Curr. Opin. Urol , vol.17 , pp. 358-362
    • Merseburger, A.S.1    Kuczyk, M.A.2
  • 18
    • 84863007712 scopus 로고    scopus 로고
    • Germline prognostic markers for urinary bladder cancer: Obstacles and opportunities
    • Chang, D.W.; Gu, J.; Wu, X. Germline prognostic markers for urinary bladder cancer: Obstacles and opportunities. Urol. Oncol. 2012, 30, 524–532.
    • (2012) Urol. Oncol , vol.30 , pp. 524-532
    • Chang, D.W.1    Gu, J.2    Wu, X.3
  • 19
    • 84864160745 scopus 로고    scopus 로고
    • Division of Genomic Medicine. (accessed on 11 April 2013)
    • Division of Genomic Medicine. A Catalog of Published Genome-Wide Association Studies. Available online: http://www.genome.gov/gwastudies (accessed on 11 April 2013).
    • A Catalog of Published Genome-Wide Association Studies
  • 20
    • 79959991704 scopus 로고    scopus 로고
    • Current status of genome-wide association studies in cancer
    • Chung, C. C.; Chanock, S. J. Current status of genome-wide association studies in cancer. Hum. Genet. 2011, 130, 59–78.
    • (2011) Hum. Genet , vol.130 , pp. 59-78
    • Chung, C. C.1    Chanock, S. J.2
  • 26
    • 80053958730 scopus 로고    scopus 로고
    • A genome-wide association study of bladder cancer identifies a new susceptibility locus within SLC14A1, a urea transporter gene on chromosome 18q12.3
    • Garcia-Closas, M.; Ye, Y.; Rothman, N.; Figueroa, J.D.; Malats, N.; Dinney, C.P.; Chatterjee, N.; Prokunina-Olsson, L.; Wang, Z.; Lin, J.; et al. A genome-wide association study of bladder cancer identifies a new susceptibility locus within SLC14A1, a urea transporter gene on chromosome 18q12.3. Hum. Mol. Genet. 2011, 20, 4282–4289.
    • (2011) Hum. Mol. Genet , vol.20 , pp. 4282-4289
    • Garcia-Closas, M.1    Ye, Y.2    Rothman, N.3    Figueroa, J.D.4    Malats, N.5    Dinney, C.P.6    Chatterjee, N.7    Prokunina-Olsson, L.8    Wang, Z.9    Lin, J.10
  • 29
  • 31
    • 33646209104 scopus 로고    scopus 로고
    • Prostate stem cell antigen (PSCA) expression in human prostate cancer tissues and its potential role in prostate carcinogenesis and progression of prostate cancer
    • Zhigang, Z.; Wenlv, S. Prostate stem cell antigen (PSCA) expression in human prostate cancer tissues and its potential role in prostate carcinogenesis and progression of prostate cancer. World J. Surg. Oncol. 2004, 2, 13.
    • (2004) World J. Surg. Oncol , vol.2 , pp. 13
    • Zhigang, Z.1    Wenlv, S.2
  • 32
    • 0035956985 scopus 로고    scopus 로고
    • Anti-PSCA mAbs inhibit tumor growth and metastasis formation and prolong the survival of mice bearing human prostate cancer xenografts
    • Saffran, D.C.; Raitano, A.B.; Hubert, R.S.; Witte, O.N.; Reiter, R.E.; Jakobovits, A. Anti-PSCA mAbs inhibit tumor growth and metastasis formation and prolong the survival of mice bearing human prostate cancer xenografts. Proc. Natl. Acad. Sci. USA 2001, 98, 2658–2663.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 2658-2663
    • Saffran, D.C.1    Raitano, A.B.2    Hubert, R.S.3    Witte, O.N.4    Reiter, R.E.5    Jakobovits, A.6
  • 33
    • 44349178008 scopus 로고    scopus 로고
    • Genetic variation in PSCA is associated with susceptibility to diffuse-type gastric cancer
    • Study Group of Millennium Genome Project for Cancer
    • Study Group of Millennium Genome Project for Cancer; Sakamoto, H.; Yoshimura, K.; Saeki, N.; Katai, H.; Shimoda, T.; Matsuno, Y.; Saito, D.; Sugimura, H.; Tanioka, F.; et al. Genetic variation in PSCA is associated with susceptibility to diffuse-type gastric cancer. Nat. Genet. 2008, 40, 730–740.
    • (2008) Nat. Genet , vol.40 , pp. 730-740
    • Sakamoto, H.1    Yoshimura, K.2    Saeki, N.3    Katai, H.4    Shimoda, T.5    Matsuno, Y.6    Saito, D.7    Sugimura, H.8    Tanioka, F.9
  • 39
    • 84860600879 scopus 로고    scopus 로고
    • Expression of androgen and oestrogen receptors and its prognostic significance in urothelial neoplasm of the urinary bladder
    • Miyamoto, H.; Yao, J.L.; Chaux, A.; Zheng, Y.; Hsu, I.; Izumi, K.; Chang, C.; Messing, E.M.; Netto, G.J.; Yeh, S. Expression of androgen and oestrogen receptors and its prognostic significance in urothelial neoplasm of the urinary bladder. BJU Int. 2012, 109, 1716–1726.
    • (2012) BJU Int , vol.109 , pp. 1716-1726
    • Miyamoto, H.1    Yao, J.L.2    Chaux, A.3    Zheng, Y.4    Hsu, I.5    Izumi, K.6    Chang, C.7    Messing, E.M.8    Netto, G.J.9    Yeh, S.10
  • 40
    • 84884812420 scopus 로고    scopus 로고
    • Gender-specific differences in muscle-invasive bladder cancer: The concept of sex steroid sensitivity
    • Gakis, G.; Stenzl, A. Gender-specific differences in muscle-invasive bladder cancer: The concept of sex steroid sensitivity. World J. Urol. 2013, doi:10.1007/s00345-013-1037-z.
    • (2013) World J. Urol
    • Gakis, G.1    Stenzl, A.2
  • 41
    • 84862924597 scopus 로고    scopus 로고
    • Nuclear hormone receptor signals as new therapeutic targets for urothelial carcinoma
    • Miyamoto, H.; Zheng, Y.; Izumi, K. Nuclear hormone receptor signals as new therapeutic targets for urothelial carcinoma. Curr. Cancer Drug Targets 2012, 12, 14–22.
    • (2012) Curr. Cancer Drug Targets , vol.12 , pp. 14-22
    • Miyamoto, H.1    Zheng, Y.2    Izumi, K.3
  • 42
    • 77950501858 scopus 로고    scopus 로고
    • Modulation of the human glucuronosyltransferase UGT1A pathway by splice isoform polypeptides is mediated through protein-protein interactions
    • Bellemare, J.; Rouleau, M.; Harvey, M.; Guillemette, C. Modulation of the human glucuronosyltransferase UGT1A pathway by splice isoform polypeptides is mediated through protein-protein interactions. J. Biol. Chem. 2010, 285, 3600–3607.
    • (2010) J. Biol. Chem , vol.285 , pp. 3600-3607
    • Bellemare, J.1    Rouleau, M.2    Harvey, M.3    Guillemette, C.4
  • 44
    • 0034128936 scopus 로고    scopus 로고
    • Human UDP-glucuronosyltransferases: Metabolism, expression, and disease
    • Tukey, R.H.; Strassburg, C.P. Human UDP-glucuronosyltransferases: Metabolism, expression, and disease. Ann. Rev. Pharmacol. Toxicol. 2000, 40, 581–616.
    • (2000) Ann. Rev. Pharmacol. Toxicol , vol.40 , pp. 581-616
    • Tukey, R.H.1    Strassburg, C.P.2
  • 45
    • 0032869568 scopus 로고    scopus 로고
    • Glucuronidation of benzidine and its metabolites by cDNA-expressed human UDP-glucuronosyltransferases and pH stability of glucuronides
    • Ciotti, M.; Lakshmi, V.M.; Basu, N.; Davis, B.B.; Owens, I.S.; Zenser, T.V. Glucuronidation of benzidine and its metabolites by cDNA-expressed human UDP-glucuronosyltransferases and pH stability of glucuronides. Carcinogenesis 1999, 20, 1963–1969.
    • (1999) Carcinogenesis , vol.20 , pp. 1963-1969
    • Ciotti, M.1    Lakshmi, V.M.2    Basu, N.3    Davis, B.B.4    Owens, I.S.5    Zenser, T.V.6
  • 46
    • 18344397488 scopus 로고    scopus 로고
    • Metabolism of N-acetylbenzidine and initiation of bladder cancer
    • 506, 507
    • Zenser, T.V.; Lakshmi, V.M.; Hsu, F.F.; Davis, B.B. Metabolism of N-acetylbenzidine and initiation of bladder cancer. Mutat. Res. 2002, 506–507, 29–40.
    • (2002) Mutat. Res , pp. 29-40
    • Zenser, T.V.1    Lakshmi, V.M.2    Hsu, F.F.3    Davis, B.B.4
  • 47
    • 84875412938 scopus 로고    scopus 로고
    • Refining the UGT1A haplotype associated with irinotecan-induced hematological toxicity in metastatic colorectal cancer patients treated with 5-fluorouracil/ irinotecan-based regimens
    • Levesque, E.; Belanger, A.S.; Harvey, M.; Couture, F.; Jonker, D.; Innocenti, F.; Cecchin, E.; Toffoli, G.; Guillemette, C. Refining the UGT1A haplotype associated with irinotecan-induced hematological toxicity in metastatic colorectal cancer patients treated with 5-fluorouracil/ irinotecan-based regimens. J. Pharmacol. Exp. Ther. 2013, 345, 95–101.
    • (2013) J. Pharmacol. Exp. Ther , vol.345 , pp. 95-101
    • Levesque, E.1    Belanger, A.S.2    Harvey, M.3    Couture, F.4    Jonker, D.5    Innocenti, F.6    Cecchin, E.7    Toffoli, G.8    Guillemette, C.9
  • 49
    • 54049104346 scopus 로고    scopus 로고
    • Epidemiology and genetic susceptibility to bladder cancer
    • Wu, X.; Ros, M.M.; Gu, J.; Kiemeney, L. Epidemiology and genetic susceptibility to bladder cancer. BJU Int. 2008, 102, 1207–1215.
    • (2008) BJU Int , vol.102 , pp. 1207-1215
    • Wu, X.1    Ros, M.M.2    Gu, J.3    Kiemeney, L.4
  • 50
    • 54349087788 scopus 로고    scopus 로고
    • Myc’s broad reach
    • Eilers, M.; Eisenman, R.N. Myc’s broad reach. Genes Dev. 2008, 22, 2755–2766.
    • (2008) Genes Dev , vol.22 , pp. 2755-2766
    • Eilers, M.1    Eisenman, R.N.2
  • 51
    • 79952833775 scopus 로고    scopus 로고
    • MYC inactivation elicits oncogene addiction through both tumor cell-intrinsic and host-dependent mechanisms
    • Felsher, D.W. MYC inactivation elicits oncogene addiction through both tumor cell-intrinsic and host-dependent mechanisms. Genes Cancer 2010, 1, 597–604.
    • (2010) Genes Cancer , vol.1 , pp. 597-604
    • Felsher, D.W.1
  • 52
    • 1642430733 scopus 로고    scopus 로고
    • Myc pathways provoking cell suicide and cancer
    • Nilsson, J.A.; Cleveland, J.L. Myc pathways provoking cell suicide and cancer. Oncogene 2003, 22, 9007–9021.
    • (2003) Oncogene , vol.22 , pp. 9007-9021
    • Nilsson, J.A.1    Cleveland, J.L.2
  • 57
    • 66749109824 scopus 로고    scopus 로고
    • Common genetic variants on 8q24 contribute to susceptibility to bladder cancer in a Chinese population
    • Wang, M.; Wang, M.; Zhang, W.; Yuan, L.; Fu, G.; Wei, Q.; Zhang, Z. Common genetic variants on 8q24 contribute to susceptibility to bladder cancer in a Chinese population. Carcinogenesis 2009, 30, 991–996.
    • (2009) Carcinogenesis , vol.30 , pp. 991-996
    • Wang, M.1    Wang, M.2    Zhang, W.3    Yuan, L.4    Fu, G.5    Wei, Q.6    Zhang, Z.7
  • 60
    • 84860750491 scopus 로고    scopus 로고
    • An enhancer from the 8q24 prostate cancer risk region is sufficient to direct reporter gene expression to a subset of prostate stem-like epithelial cells in transgenic mice
    • Ting, M.C.; Liao, C.P.; Yan, C.; Jia, L.; Groshen, S.; Frenkel, B.; Roy-Burman, P.; Coetzee, G.A.; Maxson, R. An enhancer from the 8q24 prostate cancer risk region is sufficient to direct reporter gene expression to a subset of prostate stem-like epithelial cells in transgenic mice. Dis. Models Mech. 2012, 5, 366–374.
    • (2012) Dis. Models Mech , vol.5 , pp. 366-374
    • Ting, M.C.1    Liao, C.P.2    Yan, C.3    Jia, L.4    Groshen, S.5    Frenkel, B.6    Roy-Burman, P.7    Coetzee, G.A.8    Maxson, R.9
  • 63
    • 77749323471 scopus 로고    scopus 로고
    • Upregulation of c-MYC in cis through a large chromatin loop linked to a cancer risk-associated single-nucleotide polymorphism in colorectal cancer cells
    • Wright, J.B.; Brown, S.J.; Cole, M.D. Upregulation of c-MYC in cis through a large chromatin loop linked to a cancer risk-associated single-nucleotide polymorphism in colorectal cancer cells. Mol. Cell. Biol. 2010, 30, 1411–1420.
    • (2010) Mol. Cell. Biol , vol.30 , pp. 1411-1420
    • Wright, J.B.1    Brown, S.J.2    Cole, M.D.3
  • 64
    • 77956295666 scopus 로고    scopus 로고
    • An 8q24 gene desert variant associated with prostate cancer risk confers differential in vivo activity to a MYC enhancer
    • Wasserman, N.F.; Aneas, I.; Nobrega, M.A. An 8q24 gene desert variant associated with prostate cancer risk confers differential in vivo activity to a MYC enhancer. Genome Res. 2010, 20, 1191–1197.
    • (2010) Genome Res , vol.20 , pp. 1191-1197
    • Wasserman, N.F.1    Aneas, I.2    Nobrega, M.A.3
  • 67
    • 33644841931 scopus 로고    scopus 로고
    • Genetic alterations in urothelial bladder carcinoma: An updated review
    • Mhawech-Fauceglia, P.; Cheney, R.T.; Schwaller, J. Genetic alterations in urothelial bladder carcinoma: An updated review. Cancer 2006, 106, 1205–1216.
    • (2006) Cancer , vol.106 , pp. 1205-1216
    • Mhawech-Fauceglia, P.1    Cheney, R.T.2    Schwaller, J.3
  • 69
    • 77955487110 scopus 로고    scopus 로고
    • Variation at the TERT locus and predisposition for cancer
    • Baird, D.M. Variation at the TERT locus and predisposition for cancer. Expert Rev. Mol. Med. 2010, 12, e16.
    • (2010) Expert Rev. Mol. Med , vol.12 , pp. e16
    • Baird, D.M.1
  • 70
    • 84858750992 scopus 로고    scopus 로고
    • Regulation of the human catalytic subunit of telomerase (hTERT)
    • Daniel, M.; Peek, G.W.; Tollefsbol, T.O. Regulation of the human catalytic subunit of telomerase (hTERT). Gene 2012, 498, 135–146.
    • (2012) Gene , vol.498 , pp. 135-146
    • Daniel, M.1    Peek, G.W.2    Tollefsbol, T.O.3
  • 72
    • 84862812237 scopus 로고    scopus 로고
    • Surrogate tissue telomere length and cancer risk: Shorter or longer?
    • Hou, L.; Zhang, X.; Gawron, A.J.; Liu, J. Surrogate tissue telomere length and cancer risk: Shorter or longer? Cancer Lett. 2012, 319, 130–135.
    • (2012) Cancer Lett , vol.319 , pp. 130-135
    • Hou, L.1    Zhang, X.2    Gawron, A.J.3    Liu, J.4
  • 73
    • 43549110556 scopus 로고    scopus 로고
    • Increased copy number of the TERT and TERC telomerase subunit genes in cancer cells
    • Cao, Y.; Bryan, T.M.; Reddel, R.R. Increased copy number of the TERT and TERC telomerase subunit genes in cancer cells. Cancer Sci. 2008, 99, 1092–1099.
    • (2008) Cancer Sci , vol.99 , pp. 1092-1099
    • Cao, Y.1    Bryan, T.M.2    Reddel, R.R.3
  • 74
    • 0034805276 scopus 로고    scopus 로고
    • A novel gene, CRR9, which was up-regulated in CDDP-resistant ovarian tumor cell line, was associated with apoptosis
    • Yamamoto, K.; Okamoto, A.; Isonishi, S.; Ochiai, K.; Ohtake, Y. A novel gene, CRR9, which was up-regulated in CDDP-resistant ovarian tumor cell line, was associated with apoptosis. Biochem. and Biophys. Res. Commun. 2001, 280, 1148–1154.
    • (2001) Biochem. and Biophys. Res. Commun , vol.280 , pp. 1148-1154
    • Yamamoto, K.1    Okamoto, A.2    Isonishi, S.3    Ochiai, K.4    Ohtake, Y.5
  • 78
    • 79955818260 scopus 로고    scopus 로고
    • A genome-wide association study identifies a locus on chromosome 14q21 as a predictor of leukocyte telomere length and as a marker of susceptibility for bladder cancer
    • Gu, J.; Chen, M.; Shete, S.; Amos, C.I.; Kamat, A.; Ye, Y.; Lin, J.; Dinney, C.P.; Wu, X. A genome-wide association study identifies a locus on chromosome 14q21 as a predictor of leukocyte telomere length and as a marker of susceptibility for bladder cancer. Cancer Prev. Res. 2011, 4, 514–521.
    • (2011) Cancer Prev. Res , vol.4 , pp. 514-521
    • Gu, J.1    Chen, M.2    Shete, S.3    Amos, C.I.4    Kamat, A.5    Ye, Y.6    Lin, J.7    Dinney, C.P.8    Wu, X.9
  • 79
    • 84875436593 scopus 로고    scopus 로고
    • Longer telomere length in peripheral white blood cells is associated with risk of lung cancer and the rs2736100 (CLPTM1L-TERT) polymorphism in a prospective cohort study among women in China
    • Lan, Q.; Cawthon, R.; Gao, Y.; Hu, W.; Hosgood, H.D., III; Barone-Adesi, F.; Ji, B.T.; Bassig, B.; Chow, W.H.; Shu, X.; et al. Longer telomere length in peripheral white blood cells is associated with risk of lung cancer and the rs2736100 (CLPTM1L-TERT) polymorphism in a prospective cohort study among women in China. PLoS One 2013, 8, e59230.
    • (2013) PLoS One , vol.8 , pp. e59230
    • Lan, Q.1    Cawthon, R.2    Gao, Y.3    Hu, W.4    Hosgood, H.D.5    Barone-Adesi, F.6    Ji, B.T.7    Bassig, B.8    Chow, W.H.9    Shu, X.10
  • 81
    • 69449090136 scopus 로고    scopus 로고
    • The TERT-CLPTM1L lung cancer susceptibility variant associates with higher DNA adduct formation in the lung
    • Zienolddiny, S.; Skaug, V.; Landvik, N.E.; Ryberg, D.; Phillips, D.H.; Houlston, R.; Haugen, A. The TERT-CLPTM1L lung cancer susceptibility variant associates with higher DNA adduct formation in the lung. Carcinogenesis 2009, 30, 1368–1371.
    • (2009) Carcinogenesis , vol.30 , pp. 1368-1371
    • Zienolddiny, S.1    Skaug, V.2    Landvik, N.E.3    Ryberg, D.4    Phillips, D.H.5    Houlston, R.6    Haugen, A.7
  • 83
    • 84855178148 scopus 로고    scopus 로고
    • Histone deacetylase inhibition as an anticancer telomerase-targeting strategy
    • Rahman, R.; Grundy, R. Histone deacetylase inhibition as an anticancer telomerase-targeting strategy. Int. J. Cancer 2011, 129, 2765–2774.
    • (2011) Int. J. Cancer , vol.129 , pp. 2765-2774
    • Rahman, R.1    Grundy, R.2
  • 85
    • 78149483788 scopus 로고    scopus 로고
    • FGFR3, HRAS, KRAS, NRAS and PIK3CA mutations in bladder cancer and their potential as biomarkers for surveillance and therapy
    • Kompier, L.C.; Lurkin, I.; van der Aa, M.N.; van Rhijn, B.W.; van der Kwast, T.H.; Zwarthoff, E.C. FGFR3, HRAS, KRAS, NRAS and PIK3CA mutations in bladder cancer and their potential as biomarkers for surveillance and therapy. PLoS One 2010, 5, e13821.
    • (2010) PLoS One , vol.5 , pp. e13821
    • Kompier, L.C.1    Lurkin, I.2    van der Aa, M.N.3    van Rhijn, B.W.4    van der Kwast, T.H.5    Zwarthoff, E.C.6
  • 88
    • 68949211709 scopus 로고    scopus 로고
    • Genetics of human gene expression: Mapping DNA variants that influence gene expression
    • Cheung, V.G.; Spielman, R.S. Genetics of human gene expression: Mapping DNA variants that influence gene expression. Nat. Rev. Genet. 2009, 10, 595–604.
    • (2009) Nat. Rev. Genet , vol.10 , pp. 595-604
    • Cheung, V.G.1    Spielman, R.S.2
  • 91
    • 84862777063 scopus 로고    scopus 로고
    • Common genetic variants at the 11q13.3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression
    • S1–S2
    • Schodel, J.; Bardella, C.; Sciesielski, L.K.; Brown, J.M.; Pugh, C.W.; Buckle, V.; Tomlinson, I.P.; Ratcliffe, P.J.; Mole, D.R. Common genetic variants at the 11q13.3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression. Nat. Genet. 2012, 44, 420–425, S1–S2.
    • (2012) Nat. Genet , vol.44 , pp. 420-425
    • Schodel, J.1    Bardella, C.2    Sciesielski, L.K.3    Brown, J.M.4    Pugh, C.W.5    Buckle, V.6    Tomlinson, I.P.7    Ratcliffe, P.J.8    Mole, D.R.9
  • 92
    • 84873351133 scopus 로고    scopus 로고
    • The long non-coding RNAs, a new cancer diagnostic and therapeutic gold mine
    • Qi, P.; Du, X. The long non-coding RNAs, a new cancer diagnostic and therapeutic gold mine. Mod. Pathol. 2013, 26, 155–165.
    • (2013) Mod. Pathol , vol.26 , pp. 155-165
    • Qi, P.1    Du, X.2
  • 96
    • 84891943602 scopus 로고    scopus 로고
    • Alternative splicing and its impact as a cancer diagnostic marker
    • Kim, Y.J.; Kim, H.S. Alternative splicing and its impact as a cancer diagnostic marker. Genomics Inf. 2012, 10, 74–80.
    • (2012) Genomics Inf , vol.10 , pp. 74-80
    • Kim, Y.J.1    Kim, H.S.2
  • 97
    • 13944252065 scopus 로고    scopus 로고
    • A germline DNA polymorphism enhances alternative splicing of the KLF6 tumor suppressor gene and is associated with increased prostate cancer risk
    • Narla, G.; Difeo, A.; Reeves, H.L.; Schaid, D.J.; Hirshfeld, J.; Hod, E.; Katz, A.; Isaacs, W.B.; Hebbring, S.; Komiya, A.; et al. A germline DNA polymorphism enhances alternative splicing of the KLF6 tumor suppressor gene and is associated with increased prostate cancer risk. Cancer Res. 2005, 65, 1213–1222.
    • (2005) Cancer Res , vol.65 , pp. 1213-1222
    • Narla, G.1    Difeo, A.2    Reeves, H.L.3    Schaid, D.J.4    Hirshfeld, J.5    Hod, E.6    Katz, A.7    Isaacs, W.B.8    Hebbring, S.9    Komiya, A.10
  • 98
    • 84857691987 scopus 로고    scopus 로고
    • Genome-wide identification of SNPs in microRNA genes and the SNP effects on microRNA target binding and biogenesis
    • Gong, J.; Tong, Y.; Zhang, H.M.; Wang, K.; Hu, T.; Shan, G.; Sun, J.; Guo, A.Y. Genome-wide identification of SNPs in microRNA genes and the SNP effects on microRNA target binding and biogenesis. Hum. Mutat. 2012, 33, 254–263.
    • (2012) Hum. Mutat , vol.33 , pp. 254-263
    • Gong, J.1    Tong, Y.2    Zhang, H.M.3    Wang, K.4    Hu, T.5    Shan, G.6    Sun, J.7    Guo, A.Y.8
  • 99
    • 84867501050 scopus 로고    scopus 로고
    • Common genetic variants in miR-1206 (8q24.2) and miR-612 (11q13.3) affect biogenesis of mature miRNA forms
    • Kim, H.K.; Prokunina-Olsson, L.; Chanock, S.J. Common genetic variants in miR-1206 (8q24.2) and miR-612 (11q13.3) affect biogenesis of mature miRNA forms. PloS One 2012, 7, e47454.
    • (2012) PloS One , vol.7 , pp. e47454
    • Kim, H.K.1    Prokunina-Olsson, L.2    Chanock, S.J.3
  • 100
    • 84868613310 scopus 로고    scopus 로고
    • MiR-196a binding-site SNP regulates RAP1A expression contributing to esophageal squamous cell carcinoma risk and metastasis
    • Wang, K.; Li, J.; Guo, H.; Xu, X.; Xiong, G.; Guan, X.; Liu, B.; Li, J.; Chen, X.; Yang, K.; et al. MiR-196a binding-site SNP regulates RAP1A expression contributing to esophageal squamous cell carcinoma risk and metastasis. Carcinogenesis 2012, 33, 2147–2154.
    • (2012) Carcinogenesis , vol.33 , pp. 2147-2154
    • Wang, K.1    Li, J.2    Guo, H.3    Xu, X.4    Xiong, G.5    Guan, X.6    Liu, B.7    Li, J.8    Chen, X.9    Yang, K.10
  • 101
    • 1542757108 scopus 로고    scopus 로고
    • Novel intronic polymorphisms in the RET proto-oncogene and their association with Hirschsprung disease
    • Fitze, G.; Schierz, M.; Kuhlisch, E.; Schreiber, M.; Ziegler, A.; Roesner, D.; Schackert, H.K. Novel intronic polymorphisms in the RET proto-oncogene and their association with Hirschsprung disease. Hum. Mutat. 2003, 22, 177.
    • (2003) Hum. Mutat , vol.22 , pp. 177
    • Fitze, G.1    Schierz, M.2    Kuhlisch, E.3    Schreiber, M.4    Ziegler, A.5    Roesner, D.6    Schackert, H.K.7
  • 105
    • 70349623314 scopus 로고    scopus 로고
    • Cis-regulatory mutations in human disease
    • Epstein, D.J. Cis-regulatory mutations in human disease. Brief. Funct. Genomics Proteomics 2009, 8, 310–316.
    • (2009) Brief. Funct. Genomics Proteomics , vol.8 , pp. 310-316
    • Epstein, D.J.1
  • 106
    • 84869436774 scopus 로고    scopus 로고
    • Interpreting noncoding genetic variation in complex traits and human disease
    • Ward, L.D.; Kellis, M. Interpreting noncoding genetic variation in complex traits and human disease. Nat. Biotechnol. 2012, 30, 1095–1106.
    • (2012) Nat. Biotechnol , vol.30 , pp. 1095-1106
    • Ward, L.D.1    Kellis, M.2
  • 110
    • 77952574849 scopus 로고    scopus 로고
    • Uncovering the roles of rare variants in common disease through whole-genome sequencing
    • Cirulli, E.T.; Goldstein, D.B. Uncovering the roles of rare variants in common disease through whole-genome sequencing. Nat. Rev. Genet. 2010, 11, 415–425.
    • (2010) Nat. Rev. Genet , vol.11 , pp. 415-425
    • Cirulli, E.T.1    Goldstein, D.B.2
  • 111
    • 77954133026 scopus 로고    scopus 로고
    • Estimation of effect size distribution from genome-wide association studies and implications for future discoveries
    • Park, J.H.; Wacholder, S.; Gail, M.H.; Peters, U.; Jacobs, K.B.; Chanock, S.J.; Chatterjee, N. Estimation of effect size distribution from genome-wide association studies and implications for future discoveries. Nat. Genet. 2010, 42, 570–575.
    • (2010) Nat. Genet , vol.42 , pp. 570-575
    • Park, J.H.1    Wacholder, S.2    Gail, M.H.3    Peters, U.4    Jacobs, K.B.5    Chanock, S.J.6    Chatterjee, N.7
  • 112
    • 58149328823 scopus 로고    scopus 로고
    • Extending genome-wide association studies to copy-number variation
    • McCarroll, S.A. Extending genome-wide association studies to copy-number variation. Hum. Mol. Genet. 2008, 17, R135–R142.
    • (2008) Hum. Mol. Genet , vol.17 , pp. R135-R142
    • McCarroll, S.A.1
  • 113
    • 58149357365 scopus 로고    scopus 로고
    • Genome-wide association studies in cancer
    • Easton, D.F.; Eeles, R.A. Genome-wide association studies in cancer. Hum. Mol. Genet. 2008, 17, R109–R115.
    • (2008) Hum. Mol. Genet , vol.17 , pp. R109-R115
    • Easton, D.F.1    Eeles, R.A.2
  • 115
    • 77953819013 scopus 로고    scopus 로고
    • Bladder cancer or bladder cancers? Genetically distinct malignant conditions of the urothelium
    • Goebell, P.J.; Knowles, M.A. Bladder cancer or bladder cancers? Genetically distinct malignant conditions of the urothelium. Urol. Oncol. 2010, 28, 409–428.
    • (2010) Urol. Oncol , vol.28 , pp. 409-428
    • Goebell, P.J.1    Knowles, M.A.2
  • 116
    • 77957549881 scopus 로고    scopus 로고
    • GWAS identifies a common breast cancer risk allele among BRCA1 carriers
    • Kraft, P.; Haiman, C.A. GWAS identifies a common breast cancer risk allele among BRCA1 carriers. Nat. Genet. 2010, 42, 819–820.
    • (2010) Nat. Genet , vol.42 , pp. 819-820
    • Kraft, P.1    Haiman, C.A.2
  • 117
    • 39449083161 scopus 로고    scopus 로고
    • Design considerations for genomic association studies: Importance of gene-environment interactions
    • Le Marchand, L.; Wilkens, L.R. Design considerations for genomic association studies: Importance of gene-environment interactions. Cancer Epidemiol. Biomark. Prev. 2008, 17, 263–267.
    • (2008) Cancer Epidemiol. Biomark. Prev , vol.17 , pp. 263-267
    • Le Marchand, L.1    Wilkens, L.R.2
  • 119
    • 79960053980 scopus 로고    scopus 로고
    • Genetic architecture of cancer and other complex diseases: Lessons learned and future directions
    • Hindorff, L.A.; Gillanders, E.M.; Manolio, T.A. Genetic architecture of cancer and other complex diseases: Lessons learned and future directions. Carcinogenesis 2011, 32, 945–954.
    • (2011) Carcinogenesis , vol.32 , pp. 945-954
    • Hindorff, L.A.1    Gillanders, E.M.2    Manolio, T.A.3
  • 122
    • 77954136357 scopus 로고    scopus 로고
    • Hints of hidden heritability in GWAS
    • Gibson, G. Hints of hidden heritability in GWAS. Nat. Genet. 2010, 42, 558–560.
    • (2010) Nat. Genet , vol.42 , pp. 558-560
    • Gibson, G.1


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