-
1
-
-
79952232216
-
Global cancer statistics
-
Jemal, A. et al. (2011) Global cancer statistics. CA. Cancer J. Clin., 61, 69-90.
-
(2011)
CA. Cancer J. Clin.
, vol.61
, pp. 69-90
-
-
Jemal, A.1
-
2
-
-
77954323877
-
Esophageal cancer: Clinical Practice Guidelines for diagnosis, treatment and follow-up
-
Esmo Guidelines Working Group
-
Stahl, M. et al.; ESMO Guidelines Working Group. (2010) Esophageal cancer: Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann. Oncol., 21 Suppl 5, v46-v49.
-
(2010)
Ann. Oncol.
, vol.21
, Issue.SUPPL. 5
-
-
Stahl, M.1
-
3
-
-
79955532664
-
MUC1 induces metastasis in esophageal squamous cell carcinoma by upregulating matrix metalloproteinase 13
-
Ye, Q. et al. (2011) MUC1 induces metastasis in esophageal squamous cell carcinoma by upregulating matrix metalloproteinase 13. Lab. Invest., 91, 778-787.
-
(2011)
Lab. Invest.
, vol.91
, pp. 778-787
-
-
Ye, Q.1
-
4
-
-
33645294070
-
Oncomirs - microRNAs with a role in cancer
-
Esquela-Kerscher, A. et al. (2006) Oncomirs - microRNAs with a role in cancer. Nat. Rev. Cancer, 6, 259-269.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 259-269
-
-
Esquela-Kerscher, A.1
-
5
-
-
11844262661
-
Phylogenetic shadowing and computational identification of human microRNA genes
-
Berezikov, E. et al. (2005) Phylogenetic shadowing and computational identification of human microRNA genes. Cell, 120, 21-24.
-
(2005)
Cell
, vol.120
, pp. 21-24
-
-
Berezikov, E.1
-
6
-
-
28344440823
-
MicroRNA function: multiple mechanisms for a tiny RNA?
-
Pillai, R.S. (2005) MicroRNA function: multiple mechanisms for a tiny RNA? RNA, 11, 1753-1761.
-
(2005)
RNA
, vol.11
, pp. 1753-1761
-
-
Pillai, R.S.1
-
7
-
-
24644446398
-
Ribo-gnome: the big world of small RNAs
-
Zamore, P.D. et al. (2005) Ribo-gnome: the big world of small RNAs. Science, 309, 1519-1524.
-
(2005)
Science
, vol.309
, pp. 1519-1524
-
-
Zamore, P.D.1
-
8
-
-
33644857025
-
Gene regulation by microRNAs
-
Carthew, R.W. (2006) Gene regulation by microRNAs. Curr. Opin. Genet. Dev., 16, 203-208.
-
(2006)
Curr. Opin. Genet. Dev.
, vol.16
, pp. 203-208
-
-
Carthew, R.W.1
-
9
-
-
83555177355
-
MicroRNA-375 inhibits tumour growth and metastasis in oesophageal squamous cell carcinoma through repressing insulin-like growth factor 1 receptor
-
Kong, K.L. et al. (2012) MicroRNA-375 inhibits tumour growth and metastasis in oesophageal squamous cell carcinoma through repressing insulin-like growth factor 1 receptor. Gut, 61, 33-42.
-
(2012)
Gut
, vol.61
, pp. 33-42
-
-
Kong, K.L.1
-
10
-
-
79953187233
-
microRNA-92a promotes lymph node metastasis of human esophageal squamous cell carcinoma via E-cadherin
-
Chen, Z.L. et al. (2011) microRNA-92a promotes lymph node metastasis of human esophageal squamous cell carcinoma via E-cadherin. J. Biol. Chem., 286, 10725-10734.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 10725-10734
-
-
Chen, Z.L.1
-
11
-
-
77952918274
-
Genetic variation in microRNA networks: the implications for cancer research
-
Ryan, B.M. et al. (2010) Genetic variation in microRNA networks: the implications for cancer research. Nat. Rev. Cancer, 10, 389-402.
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 389-402
-
-
Ryan, B.M.1
-
12
-
-
80755187828
-
A functional variant at the miR-184 binding site in TNFAIP2 and risk of squamous cell carcinoma of the head and neck
-
Liu, Z. et al. (2011) A functional variant at the miR-184 binding site in TNFAIP2 and risk of squamous cell carcinoma of the head and neck. Carcinogenesis, 32, 1668-1674.
-
(2011)
Carcinogenesis
, vol.32
, pp. 1668-1674
-
-
Liu, Z.1
-
13
-
-
84872175629
-
REV3L 3'UTR 460 T>C polymorphism in micro-RNA target sites contributes to lung cancer susceptibility
-
Zhang, S. et al. (2012) REV3L 3'UTR 460 T>C polymorphism in micro-RNA target sites contributes to lung cancer susceptibility. Oncogene.
-
(2012)
Oncogene
-
-
Zhang, S.1
-
14
-
-
52949119537
-
MicroRNA target site polymorphisms and human disease
-
Sethupathy, P. et al. (2008) MicroRNA target site polymorphisms and human disease. Trends Genet., 24, 489-497.
-
(2008)
Trends Genet
, vol.24
, pp. 489-497
-
-
Sethupathy, P.1
-
15
-
-
79960962854
-
Genetic variation in an miRNA-1827 binding site in MYCL1 alters susceptibility to small-cell lung cancer
-
Xiong, F. et al. (2011) Genetic variation in an miRNA-1827 binding site in MYCL1 alters susceptibility to small-cell lung cancer. Cancer Res., 71, 5175-5181.
-
(2011)
Cancer Res
, vol.71
, pp. 5175-5181
-
-
Xiong, F.1
-
16
-
-
84857926657
-
The role of microRNA-binding site polymorphisms in DNA repair genes as risk factors for bladder cancer and breast cancer and their impact on radiotherapy outcomes
-
Teo, M.T. et al. (2012) The role of microRNA-binding site polymorphisms in DNA repair genes as risk factors for bladder cancer and breast cancer and their impact on radiotherapy outcomes. Carcinogenesis, 33, 581-586.
-
(2012)
Carcinogenesis
, vol.33
, pp. 581-586
-
-
Teo, M.T.1
-
17
-
-
0142024483
-
Rap1 GTPase: functions, regulation, and malignancy
-
Hattori, M. et al. (2003) Rap1 GTPase: functions, regulation, and malignancy. J. Biochem., 134, 479-484.
-
(2003)
J. Biochem.
, vol.134
, pp. 479-484
-
-
Hattori, M.1
-
18
-
-
4043069909
-
Rap1 and SPA-1 in hematologic malignancy
-
Kometani, K. et al. (2004) Rap1 and SPA-1 in hematologic malignancy. Trends Mol. Med., 10, 401-408.
-
(2004)
Trends Mol. Med.
, vol.10
, pp. 401-408
-
-
Kometani, K.1
-
19
-
-
84861679836
-
EGFR-dependent pancreatic carcinoma cell metastasis through Rap1 activation
-
Huang, M. et al. (2012) EGFR-dependent pancreatic carcinoma cell metastasis through Rap1 activation. Oncogene, 31, 2783-2793.
-
(2012)
Oncogene
, vol.31
, pp. 2783-2793
-
-
Huang, M.1
-
20
-
-
67449124367
-
Activation of Rap1 promotes prostate cancer metastasis
-
Bailey, C.L. et al. (2009) Activation of Rap1 promotes prostate cancer metastasis. Cancer Res., 69, 4962-4968.
-
(2009)
Cancer Res
, vol.69
, pp. 4962-4968
-
-
Bailey, C.L.1
-
21
-
-
77956626748
-
Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54
-
Wang, L.D. et al. (2010) Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54. Nat. Genet., 42, 759-763.
-
(2010)
Nat. Genet.
, vol.42
, pp. 759-763
-
-
Wang, L.D.1
-
22
-
-
77956623860
-
A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma
-
Abnet, C.C. et al. (2010) A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma. Nat. Genet., 42, 764-767.
-
(2010)
Nat. Genet.
, vol.42
, pp. 764-767
-
-
Abnet, C.C.1
-
23
-
-
0032560506
-
Mitogenic and oncogenic properties of the small G protein Rap1b
-
Altschuler, D.L. et al. (1998) Mitogenic and oncogenic properties of the small G protein Rap1b. Proc. Natl. Acad. Sci. U.S.A., 95, 7475-7479.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 7475-7479
-
-
Altschuler, D.L.1
-
24
-
-
33748054771
-
Ras-associated protein-1 regulates extracellular signal-regulated kinase activation and migration in melanoma cells: two processes important to melanoma tumorigenesis and metastasis
-
Gao, L. et al. (2006) Ras-associated protein-1 regulates extracellular signal-regulated kinase activation and migration in melanoma cells: two processes important to melanoma tumorigenesis and metastasis. Cancer Res., 66, 7880-7888.
-
(2006)
Cancer Res
, vol.66
, pp. 7880-7888
-
-
Gao, L.1
-
25
-
-
0037223817
-
The high-risk human papillomavirus type 16 E6 counters the GAP function of E6TP1 toward small Rap G proteins
-
Singh, L. et al. (2003) The high-risk human papillomavirus type 16 E6 counters the GAP function of E6TP1 toward small Rap G proteins. J. Virol., 77, 1614-1620.
-
(2003)
J. Virol.
, vol.77
, pp. 1614-1620
-
-
Singh, L.1
-
26
-
-
33846449909
-
RET/papillary thyroid carcinoma oncogenic signaling through the Rap1 small GTPase
-
De Falco, V. et al. (2007) RET/papillary thyroid carcinoma oncogenic signaling through the Rap1 small GTPase. Cancer Res., 67, 381-390.
-
(2007)
Cancer Res
, vol.67
, pp. 381-390
-
-
De Falco, V.1
-
27
-
-
33144487872
-
Rap1GAP inhibits tumor growth in oropharyngeal squamous cell carcinoma
-
Zhang, Z. et al. (2006) Rap1GAP inhibits tumor growth in oropharyngeal squamous cell carcinoma. Am. J. Pathol., 168, 585-596.
-
(2006)
Am. J. Pathol.
, vol.168
, pp. 585-596
-
-
Zhang, Z.1
-
28
-
-
34748877626
-
Downregulation of Rap1GAP contributes to Ras transformation
-
Tsygankova, O.M. et al. (2007) Downregulation of Rap1GAP contributes to Ras transformation. Mol. Cell. Biol., 27, 6647-6658.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 6647-6658
-
-
Tsygankova, O.M.1
-
29
-
-
77953444708
-
Downregulation of Rap1GAP in human tumor cells alters cell/matrix and cell/cell adhesion
-
Tsygankova, O.M. et al. (2010) Downregulation of Rap1GAP in human tumor cells alters cell/matrix and cell/cell adhesion. Mol. Cell. Biol., 30, 3262-3274.
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 3262-3274
-
-
Tsygankova, O.M.1
-
30
-
-
18744368073
-
Rap1 reverses transcriptional repression of TGFbeta type II receptor by a mechanism involving AP-1 in the human pancreatic cancer cell line UK Pan-1
-
Fralix, K.D. et al. (2003) Rap1 reverses transcriptional repression of TGFbeta type II receptor by a mechanism involving AP-1 in the human pancreatic cancer cell line, UK Pan-1. J. Cell. Physiol., 194, 88-99.
-
(2003)
J. Cell. Physiol.
, vol.194
, pp. 88-99
-
-
Fralix, K.D.1
-
31
-
-
76749116196
-
Downregulation of Rap1GAP through epigenetic silencing and loss of heterozygosity promotes invasion and progression of thyroid tumors
-
Zuo, H. et al. (2010) Downregulation of Rap1GAP through epigenetic silencing and loss of heterozygosity promotes invasion and progression of thyroid tumors. Cancer Res., 70, 1389-1397.
-
(2010)
Cancer Res
, vol.70
, pp. 1389-1397
-
-
Zuo, H.1
-
32
-
-
0037423929
-
DOCK4, a GTPase activator, is disrupted during tumorigenesis
-
Yajnik, V. et al. (2003) DOCK4, a GTPase activator, is disrupted during tumorigenesis. Cell, 112, 673-684.
-
(2003)
Cell
, vol.112
, pp. 673-684
-
-
Yajnik, V.1
-
33
-
-
0029879450
-
Matrix metalloproteinase 2 and 9 in esophageal cancer
-
Kataoka, M. et al. (1996) Matrix metalloproteinase 2 and 9 in esophageal cancer. Int. J. Oncol., 8, 773-779.
-
(1996)
Int. J. Oncol.
, vol.8
, pp. 773-779
-
-
Kataoka, M.1
-
34
-
-
45549107951
-
Rap1GAP promotes invasion via induction of matrix metalloproteinase 9 secretion, which is associated with poor survival in low N-stage squamous cell carcinoma
-
Mitra, R.S. et al. (2008) Rap1GAP promotes invasion via induction of matrix metalloproteinase 9 secretion, which is associated with poor survival in low N-stage squamous cell carcinoma. Cancer Res., 68, 3959-3969.
-
(2008)
Cancer Res
, vol.68
, pp. 3959-3969
-
-
Mitra, R.S.1
-
35
-
-
2142654329
-
MicroRNA-directed cleavage of HOXB8 mRNA
-
Yekta, S. et al. (2004) MicroRNA-directed cleavage of HOXB8 mRNA. Science, 304, 594-596.
-
(2004)
Science
, vol.304
, pp. 594-596
-
-
Yekta, S.1
-
36
-
-
34247648712
-
MicroRNA miR-181a correlates with morphological sub-class of acute myeloid leukaemia and the expression of its target genes in global genome-wide analysis
-
Debernardi, S. et al. (2007) MicroRNA miR-181a correlates with morphological sub-class of acute myeloid leukaemia and the expression of its target genes in global genome-wide analysis. Leukemia, 21, 912-916.
-
(2007)
Leukemia
, vol.21
, pp. 912-916
-
-
Debernardi, S.1
-
37
-
-
0036090290
-
Overexpression of the myeloid leukemiaassociated Hoxa9 gene in bone marrow cells induces stem cell expansion
-
Thorsteinsdottir, U. et al. (2002) Overexpression of the myeloid leukemiaassociated Hoxa9 gene in bone marrow cells induces stem cell expansion. Blood, 99, 121-129.
-
(2002)
Blood
, vol.99
, pp. 121-129
-
-
Thorsteinsdottir, U.1
-
38
-
-
67650995908
-
microRNA miR-196a-2 and breast cancer: a genetic and epigenetic association study and functional analysis
-
Hoffman, A.E. et al. (2009) microRNA miR-196a-2 and breast cancer: a genetic and epigenetic association study and functional analysis. Cancer Res., 69, 5970-5977.
-
(2009)
Cancer Res
, vol.69
, pp. 5970-5977
-
-
Hoffman, A.E.1
-
39
-
-
56149126489
-
MicroRNA-196a targets annexin A1: a microRNAmediated mechanism of annexin A1 downregulation in cancers
-
Luthra, R. et al. (2008) MicroRNA-196a targets annexin A1: a microRNAmediated mechanism of annexin A1 downregulation in cancers. Oncogene, 27, 6667-6678.
-
(2008)
Oncogene
, vol.27
, pp. 6667-6678
-
-
Luthra, R.1
-
40
-
-
34247862190
-
MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis
-
Bloomston, M. et al. (2007) MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis. JAMA, 297, 1901-1908.
-
(2007)
JAMA
, vol.297
, pp. 1901-1908
-
-
Bloomston, M.1
-
41
-
-
65649117364
-
MicroRNA-196a is a potential marker of progression during Barrett's metaplasia-dysplasia-invasive adenocarcinoma sequence in esophagus
-
Maru, D.M. et al. (2009) MicroRNA-196a is a potential marker of progression during Barrett's metaplasia-dysplasia-invasive adenocarcinoma sequence in esophagus. Am. J. Pathol., 174, 1940-1948.
-
(2009)
Am. J. Pathol.
, vol.174
, pp. 1940-1948
-
-
Maru, D.M.1
-
42
-
-
77958536239
-
A functional variation in pre-microRNA-196a is associated with susceptibility of esophageal squamous cell carcinoma risk in Chinese Han
-
Wang, K. et al. (2010) A functional variation in pre-microRNA-196a is associated with susceptibility of esophageal squamous cell carcinoma risk in Chinese Han. Biomarkers, 15, 614-618.
-
(2010)
Biomarkers
, vol.15
, pp. 614-618
-
-
Wang, K.1
|