A germline DNA polymorphism enhances alternative splicing of the KLF6 tumor suppressor gene and is associated with increased prostate cancer risk

Cancer Research

Volumn 65, Issue 4, 2005, Pages 1213-1222

  Narla, Goutham ^a   DiFeo, Analisa ^a   Reeves, Helen L ^a   Schaid, Daniel J ^b   Hirshfeld, Jennifer ^a   Hod, Eldad ^a   Katz, Amanda ^a   Isaacs, William B ^c   Hebbring, Scott ^b   Komiya, Akira ^c   McDonnell, Shannon K ^b   Wiley, Kathleen E ^c   Jacobsen, Steven J ^b   Isaacs, Sarah D ^c   Walsh, Patrick C ^c   Zheng, S Lilly ^g   Chang, Bao Li ^g   Friedrichsen, Danielle M ^d   Stanford, Janet L ^d   Ostrander, Elaine A ^d   Chinnaiyan, Arul M ^e   Rubin, Mark A ^f   Xu, Jianfeng ^g   Thibodeau, Stephen N ^b   Friedman, Scott L ^a   Martignetti, John A ^a   more..

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b MAYO CLINIC   (United States)

^c DEPARTMENT OF PATHOLOGY   (United States)

^d Fred Hutchinson Cancer Research Center   (United States)

^e UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^f BRIGHAM AND WOMEN S HOSPITAL   (United States)

^g WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; PROTEIN P21; PROTEIN P40; PROTEIN P53;

ARTICLE; BINDING SITE; CANCER RISK; CANCER SCREENING; CELL GROWTH; CONTROLLED STUDY; CYTOPLASM; DISEASE ASSOCIATION; DNA BINDING; DNA POLYMORPHISM; FAMILY HISTORY; GENE EXPRESSION; GENE FUNCTION; GENE LOCATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROSTATE; PROSTATE CANCER; PROTEIN BINDING; RNA SPLICING; SINGLE NUCLEOTIDE POLYMORPHISM; TUMOR SUPPRESSOR GENE; UPREGULATION;

ALLELES; ALTERNATIVE SPLICING; BINDING SITES; CELL CYCLE PROTEINS; CELL GROWTH PROCESSES; CYCLIN-DEPENDENT KINASE INHIBITOR P21; GENES, TUMOR SUPPRESSOR; GERM-LINE MUTATION; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MALE; MIDDLE AGED; NUCLEAR PROTEINS; PHOSPHOPROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROSTATIC NEOPLASMS; PROTEIN ISOFORMS; PROTO-ONCOGENE PROTEINS; RNA-BINDING PROTEINS; TRANS-ACTIVATORS; TRANSFECTION;

EID: 13944252065     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-04-4249     Document Type: Article

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