Common genetic polymorphisms modify the effect of smoking on absolute risk of bladder cancer

Cancer Research

Volumn 73, Issue 7, 2013, Pages 2211-2220

  Garcia Closas, Montserrat ^a,b   Rothman, Nathaniel ^a   Figueroa, Jonine D ^a   Prokunina Olsson, Ludmila ^a   Han, Summer S ^a   Baris, Dalsu ^a   Jacobs, Eric J ^c   Malats, Nuria ^d   De Vivo, Immaculata ^f   Albanes, Demetrius ^a   Purdue, Mark P ^a   Sharma, Sapna ^b   Fu, Yi Ping ^a   Kogevinas, Manolis ^h,i   Wang, Zhaoming ^j   Tang, Wei ^a   Tardon, Adonina ^h,k   Serra, Consol ^h   Carrato, Alfredo ^e   García Closas, Reina ^l   Lloreta, Josep ^h   Johnson, Alison ^m   Schwenn, Molly ⁿ   Karagas, Margaret R ^o   Schned, Alan ^o   Andriole, Gerald ^p   Grubb III, Robert ^p   Black, Amanda ^a   Gapstur, Susan M ^c   Thun, Michael ^c   Diver, William Ryan ^c   Weinstein, Stephanie J ^a   Virtamo, Jarmo ^q   Hunter, David J ^g   Caporaso, Neil ^a   Landi, Maria Teresa ^a   Hutchinson, Amy ^j   Burdett, Laurie ^j   Jacobs, Kevin B ^j   Yeager, Meredith ^j   Fraumeni, Joseph F ^a   Chanock, Stephen J ^a   Silverman, Debra T ^a   Chatterjee, Nilanjan ^a   more..

^a NATIONAL CANCER INSTITUTE   (United States)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^c AMERICAN CANCER SOCIETY   (United States)

^d Centro Nacional de Investigations Oncológicas   (Spain)

^e HOSPITAL RAMÓN Y CAJAL   (Spain)

^f BRIGHAM AND WOMEN S HOSPITAL   (United States)

^g HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^h UNIVERSITAT POMPEU FABRA   (Spain)

ⁱ NATIONAL SCHOOL OF PUBLIC HEALTH   (Greece)

^j SAIC FREDERICK INC   (United States)

^k UNIVERSITY OF OVIEDO   (Spain)

^l HOSPITAL UNIVERSITARIO DE CANARIAS   (Spain)

^m Vermont Cancer Registry   (United States)

ⁿ Maine Cancer Registry   (United States)

^o DARTMOUTH MEDICAL SCHOOL   (United States)

^p WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^q NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

more..

Author keywords

[No Author keywords available]

Indexed keywords

AGE DISTRIBUTION; ARTICLE; BLADDER CANCER; CANCER RISK; CAUCASIAN; CONTROLLED STUDY; GENDER; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETIC RISK; GENOTYPE ENVIRONMENT INTERACTION; GSTM1 GENE; HUMAN; MAJOR CLINICAL STUDY; ONCOGENE; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING; UNITED STATES;

EID: 84875976264     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-12-2388     Document Type: Article

References (34)

1. Silverman DT, Devesa SS, Moore LE, Rothman N. Bladder cancer. In: Schottenfeld D, Fraumeni J, eds. Cancer epidemiology and prevention. 3rd ed. New York, NY: Oxford University Press; 2006.
2. Amling CL. Diagnosis and management of superficial bladder cancer. Curr Probl Cancer 2001;25:219-78.
3. García-Closas M, Malats N, Silverman D, Dosemeci M, Kogevinas M, Hein DW, et al. NAT2 slow acetylation, GSTM1 null genotype, and risk of bladder cancer: results from the Spanish Bladder Cancer Study and meta-analyses. Lancet 2005;366:649-59.
4. Hein DW. N-acetyltransferase 2 genetic polymorphism: effects of carcinogen and haplotype on urinary bladder cancer risk. Oncogene 2006;25:1649-58.
5. Wu X, Ye Y, Kiemeney LA, Sulem P, Rafnar T, Matullo G, et al. Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancer. Nat Genet 2009;41:991-5.
6. Rothman N, Garcia-Closas M, Chatterjee N, Malats N, Wu X, Figueroa JD, et al. A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci. Nat Genet 2010;42:978-84.
7. Kiemeney LA, Thorlacius S, Sulem P, Geller F, Aben KK, Stacey SN, et al. Sequence variant on 8q24 confers susceptibility to urinary bladder cancer. Nat Genet 2008;40:1307-12.
8. Kiemeney LA, Sulem P, Besenbacher S, Vermeulen SH, Sigurdsson A, Thorleifsson G, et al. A sequence variant at 4p16.3 confers susceptibility to urinary bladder cancer. Nat Genet 2010;42:415-9.
9. Garcia-Closas M, Ye Y, Rothman N, Figueroa JD, Malats N, Dinney CP, et al. A genome-wide association study of bladder cancer identifies a new susceptibility locus within SLC14A1, a urea transporter gene on chromosome 18q12.3. Hum Mol Genet 2011;20:4282-9.
10. Rafnar T, Sulem P, Stacey SN, Geller F, Gudmundsson J, Sigurdsson A, et al. Sequence variants at the TERT-CLPTM1L locus associate with many cancer types. Nat Genet 2009;41:221-7.
11. RafnarT, Vermeulen SH, Sulem P, Thorleifsson G, Aben KK, Witjes JA, et al. European genome-wide association study identifies SLC14A1 as a new urinary bladder cancer susceptibility gene. Hum Mol Genet 2011;20:4268-81.
12. Tang W, Fu YP, Figueroa JD, Malats N, Garcia-Closas M, Chatterjee N, et al. Mapping of the UGT1A locus identifies an uncommon coding variant that affects mRNA expression and protects from bladder cancer. Hum Mol Genet 2012;21:1918-30.
13. Hunter DJ. Gene-environment interactions in human diseases. Nat Rev Genet 2005;6:287-98.
14. Garcia-Closas M, Jacobs K, Kraft P, Chatterjee N. Analysis of epidemiologic studies of genetic effects and gene-environment interactions. IARC Sci Publ 2011:281-301.
15. Moore LE, Baris DR, Figueroa JD, Garcia-Closas M, Karagas MR, Schwenn MR, et al. GSTM1 null and NAT2 slowacetylation genotypes, smoking intensity and bladder cancer risk: results from the New England bladder cancer study and NAT2 meta-analysis. Carcinogenesis 2011;32:182-9.
16. Lubin JH, Kogevinas M, Silverman D, Malats N, Garcia-Closas M, Tardon A, et al. Evidence for an intensity-dependent interaction of NAT2 acetylation genotype and cigarette smoking in the Spanish Bladder Cancer Study. Int J Epidemiol 2007;36:236-41.
17. Pritchard JK, Stephens M, Donnelly P. Inference of population structure using multilocus genotype data. Genetics 2000;155:945-59.
18. Samanic C, Kogevinas M, Dosemeci M, Malats N, Real FX, Garcia-Closas M, et al. Smoking and bladder cancer in Spain: effects of tobacco type, timing, environmental tobacco smoke, and gender. Cancer Epidemiol Biomarkers Prev 2006;15:1348-54.
19. Baris D, Karagas MR, Verrill C, Johnson A, Andrew AS, Marsit CJ, et al. A case-control study of smoking and bladder cancer risk: emergent patterns overtime. J Natl Cancer Inst 2009;101:1553-61.
20. Tang W, Fu YP, Figueroa JD, Malats N, Garcia-Closas M, Chatterjee N, et al. Mapping of the UGT1A locus identifies an uncommon coding variant that affects mRNA expression and protects from bladder cancer. Hum Mol Genet 2012;21:1918-30.
21. García-Closas M, Hein DW, Silverman D, Malats N, Yeager M, Jacobs K, et al. A single nucleotide polymorphism tags variation in the arylamineN-acetyltransferase 2 phenotype in populations of European background. Pharmacogenet Genomics 2011;21:231-6.
22. Mukherjee B, Chatterjee N. Exploiting gene-environment independence for analysis of case-control studies: an empirical Bayes-type shrinkage estimator to trade-off between bias and efficiency. Biometrics 2008;64:685-94.
23. Chen Y-H, Chatterjee N, Carroll RJ. Shrinkage estimators for robust and efficient inference in haplotype-based case-control studies. J Am Stat Assoc 2009;104:220-33.
24. Han SS, Rosenberg PS, Garcia-Closas M, Figueroa JD, Silverman D, Chanock SJ, et al. Likelihood ratio test for detecting gene (G)-environment (E) interactions under an additive risk model exploiting G-E independence for case-control data. Am J Epidemiol 2012;176:1060-7.
25. García-Closas M, Jacobs K, Kraft P, Chatterjee N. Analysis of epidemiologic studies of genetic effects and gene-environment interactions. In: Rothman N, Hainaut P, Schulte P, Smith M, Boffetta P, Perera F, eds. Molecular Epidemiology and Biomarkers: Principles and Practices. IARC Sci Publ 2001, (163), pp.281-301, ISSN: 0300-5038.
26. Bruzzi P, Green SB, Byar DP, Brinton LA, Schairer C. Estimating the population attributable risk for multiple risk factors using case-control data. Am J Epidemiol 1985;122:904-14.
27. Petracci E, Decarli A, Schairer C, Pfeiffer RM, Pee D, Masala G, et al. Risk factor modification and projections of absolute breast cancer risk. J Natl Cancer Inst 2011;103:1037-48.
28. Mooney CZ, Duval RD. Bootstrapping: a nonparametric approach to statistical inference. Sage: Newbury Park, CA; 1993.
29. Saccone NL, Culverhouse RC, Schwantesan TH, Cannon DS, Chen X, Cichon S, et al. Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD. PLoS Genet 2010;6:pii: e1001053.
30. Shields AE, Lerman C. Anticipating clinical integration of pharmacogenetic treatment strategies for addiction: are primary care physicians ready?. Clin Pharmacol Ther 2008;83:635-9.
31. Wu X, Lin J, Grossman HB, Huang M, Gu J, Etzel CJ, et al. Projecting individualized probabilities of developing bladder cancer in white individuals. J Clin Oncol 2007;25:4974-81.
32. Rothman KJ, Greenland S, Walker AM. Concepts of interaction. Am J Epidemiol 1980;112:467-70.
33. Engel LS, Taioli E, Pfeiffer R, Garcia-Closas M, Marcus PM, Lan Q, et al. Pooled analysis and meta-analysis of glutathione S-transferase M1 and bladder cancer: a HuGE review. Am J Epidemiol 2002;156:95-109.
34. Freedman ND, Silverman DT, Hollenbeck AR, Schatzkin A, Abnet CC. Association between smoking and risk of bladder cancer among men and women. JAMA 2011;306:737-45.