메뉴 건너뛰기




Volumn 28, Issue 4, 2010, Pages 409-428

Bladder cancer or bladder cancers? Genetically distinct malignant conditions of the urothelium

Author keywords

Bladder cancer; Genetic; Molecular alterations

Indexed keywords

FIBROBLAST GROWTH FACTOR RECEPTOR 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P53; RETINOBLASTOMA PROTEIN;

EID: 77953819013     PISSN: 10781439     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.urolonc.2010.04.003     Document Type: Review
Times cited : (164)

References (199)
  • 1
    • 52949091975 scopus 로고    scopus 로고
    • Bladder cancer: Clinical and pathological profile
    • Lopez-Beltran A. Bladder cancer: Clinical and pathological profile. Scand J Urol Nephrol 42 Suppl 218 (2008) 95-109
    • (2008) Scand J Urol Nephrol , vol.42 , Issue.SUPPL. 218 , pp. 95-109
    • Lopez-Beltran, A.1
  • 2
    • 33644868287 scopus 로고    scopus 로고
    • Molecular subtypes of bladder cancer: Jekyll and Hyde or chalk and cheese?
    • Knowles M.A. Molecular subtypes of bladder cancer: Jekyll and Hyde or chalk and cheese?. Carcinogenesis 27 (2006) 361-373
    • (2006) Carcinogenesis , vol.27 , pp. 361-373
    • Knowles, M.A.1
  • 3
    • 25444467767 scopus 로고    scopus 로고
    • Urothelial tumorigenesis: A tale of divergent pathways
    • Wu X.R. Urothelial tumorigenesis: A tale of divergent pathways. Nat Rev Cancer 5 (2005) 713-725
    • (2005) Nat Rev Cancer , vol.5 , pp. 713-725
    • Wu, X.R.1
  • 4
    • 52949114606 scopus 로고    scopus 로고
    • Bladder cancer subtypes defined by genomic alterations
    • Knowles M.A. Bladder cancer subtypes defined by genomic alterations. Scand J Urol Nephrol 42 4 (2008) 116-130
    • (2008) Scand J Urol Nephrol , vol.42 , Issue.4 , pp. 116-130
    • Knowles, M.A.1
  • 5
    • 0027344852 scopus 로고
    • Structural and functional diversity in the FGF receptor multigene family
    • Johnson D.E., and Williams L.T. Structural and functional diversity in the FGF receptor multigene family. Adv Cancer Res 60 (1993) 1-41
    • (1993) Adv Cancer Res , vol.60 , pp. 1-41
    • Johnson, D.E.1    Williams, L.T.2
  • 6
    • 0032841519 scopus 로고    scopus 로고
    • Frequent activating mutations of FGFR3 in human bladder and cervix carcinomas
    • Cappellen D., De Oliveira C., Ricol D., et al. Frequent activating mutations of FGFR3 in human bladder and cervix carcinomas. Nat Genet 23 (1999) 18-20
    • (1999) Nat Genet , vol.23 , pp. 18-20
    • Cappellen, D.1    De Oliveira, C.2    Ricol, D.3
  • 7
    • 10744222289 scopus 로고    scopus 로고
    • FGFR3 and TP53 gene mutations define 2 distinct pathways in urothelial cell carcinoma of the bladder
    • Bakkar A.A., Wallerand H., Radvanyi F., et al. FGFR3 and TP53 gene mutations define 2 distinct pathways in urothelial cell carcinoma of the bladder. Cancer Res 63 (2003) 8108-8112
    • (2003) Cancer Res , vol.63 , pp. 8108-8112
    • Bakkar, A.A.1    Wallerand, H.2    Radvanyi, F.3
  • 8
    • 0034969685 scopus 로고    scopus 로고
    • Frequent FGFR3 mutations in papillary noninvasive bladder (pTa) tumors
    • Billerey C., Chopin D., Aubriot-Lorton M.H., et al. Frequent FGFR3 mutations in papillary noninvasive bladder (pTa) tumors. Am J Pathol 158 (2001) 1955-1959
    • (2001) Am J Pathol , vol.158 , pp. 1955-1959
    • Billerey, C.1    Chopin, D.2    Aubriot-Lorton, M.H.3
  • 9
    • 23044479419 scopus 로고    scopus 로고
    • FGFR3 and Tp53 mutations in T1G3 transitional bladder carcinomas: Independent distribution and lack of association with prognosis
    • Hernandez S., Lopez-Knowles E., Lloreta J., et al. FGFR3 and Tp53 mutations in T1G3 transitional bladder carcinomas: Independent distribution and lack of association with prognosis. Clin Cancer Res 11 (2005) 5444-5450
    • (2005) Clin Cancer Res , vol.11 , pp. 5444-5450
    • Hernandez, S.1    Lopez-Knowles, E.2    Lloreta, J.3
  • 10
    • 0035889913 scopus 로고    scopus 로고
    • The incidence of thanatophoric dysplasia mutations in FGFR3 gene is higher in low-grade or superficial bladder carcinomas
    • Kimura T., Suzuki H., Ohashi T., et al. The incidence of thanatophoric dysplasia mutations in FGFR3 gene is higher in low-grade or superficial bladder carcinomas. Cancer 92 (2001) 2555-2561
    • (2001) Cancer , vol.92 , pp. 2555-2561
    • Kimura, T.1    Suzuki, H.2    Ohashi, T.3
  • 11
    • 0042572486 scopus 로고    scopus 로고
    • Identification of fibroblast growth factor receptor 3 mutations in urine sediment DNA samples complements cytology in bladder tumor detection
    • Rieger-Christ K.M., Mourtzinos A., Lee P.J., et al. Identification of fibroblast growth factor receptor 3 mutations in urine sediment DNA samples complements cytology in bladder tumor detection. Cancer 98 (2003) 737-744
    • (2003) Cancer , vol.98 , pp. 737-744
    • Rieger-Christ, K.M.1    Mourtzinos, A.2    Lee, P.J.3
  • 12
    • 0035825598 scopus 로고    scopus 로고
    • Loss of heterozygosity at 4p16.3 and mutation of FGFR3 in transitional cell carcinoma
    • Sibley K., Cuthbert-Heavens D., and Knowles M.A. Loss of heterozygosity at 4p16.3 and mutation of FGFR3 in transitional cell carcinoma. Oncogene 20 (2001) 686-691
    • (2001) Oncogene , vol.20 , pp. 686-691
    • Sibley, K.1    Cuthbert-Heavens, D.2    Knowles, M.A.3
  • 13
    • 0037239824 scopus 로고    scopus 로고
    • Combined microsatellite and FGFR3 mutation analysis enables a highly sensitive detection of urothelial cell carcinoma in voided urine
    • van Rhijn B.W., Lurkin I., Chopin D.K., et al. Combined microsatellite and FGFR3 mutation analysis enables a highly sensitive detection of urothelial cell carcinoma in voided urine. Clin Cancer Res 9 (2003) 257-263
    • (2003) Clin Cancer Res , vol.9 , pp. 257-263
    • van Rhijn, B.W.1    Lurkin, I.2    Chopin, D.K.3
  • 14
    • 0035866380 scopus 로고    scopus 로고
    • The fibroblast growth factor receptor 3 (FGFR3) mutation is a strong indicator of superficial bladder cancer with low recurrence rate
    • van Rhijn B.W., Lurkin I., Radvanyi F., et al. The fibroblast growth factor receptor 3 (FGFR3) mutation is a strong indicator of superficial bladder cancer with low recurrence rate. Cancer Res 61 (2001) 1265-1268
    • (2001) Cancer Res , vol.61 , pp. 1265-1268
    • van Rhijn, B.W.1    Lurkin, I.2    Radvanyi, F.3
  • 15
    • 0036772919 scopus 로고    scopus 로고
    • Frequent FGFR3 mutations in urothelial papilloma
    • van Rhijn B.W., Montironi R., Zwarthoff E.C., et al. Frequent FGFR3 mutations in urothelial papilloma. J Pathol 198 (2002) 245-251
    • (2002) J Pathol , vol.198 , pp. 245-251
    • van Rhijn, B.W.1    Montironi, R.2    Zwarthoff, E.C.3
  • 16
    • 0036926992 scopus 로고    scopus 로고
    • Novel fibroblast growth factor receptor 3 (FGFR3) mutations in bladder cancer previously identified in non-lethal skeletal disorders
    • van Rhijn B.W., van Tilborg A.A., Lurkin I., et al. Novel fibroblast growth factor receptor 3 (FGFR3) mutations in bladder cancer previously identified in non-lethal skeletal disorders. Eur J Hum Genet 10 (2002) 819-824
    • (2002) Eur J Hum Genet , vol.10 , pp. 819-824
    • van Rhijn, B.W.1    van Tilborg, A.A.2    Lurkin, I.3
  • 17
    • 0038011950 scopus 로고    scopus 로고
    • Molecular grading of urothelial cell carcinoma with fibroblast growth factor receptor 3 and MIB-1 is superior to pathologic grade for the prediction of clinical outcome
    • van Rhijn B.W., Vis A.N., van der Kwast T.H., et al. Molecular grading of urothelial cell carcinoma with fibroblast growth factor receptor 3 and MIB-1 is superior to pathologic grade for the prediction of clinical outcome. J Clin Oncol 21 (2003) 1912-1921
    • (2003) J Clin Oncol , vol.21 , pp. 1912-1921
    • van Rhijn, B.W.1    Vis, A.N.2    van der Kwast, T.H.3
  • 18
    • 13444279152 scopus 로고    scopus 로고
    • Mutations in TP53, but not FGFR3, in urothelial cell carcinoma of the bladder are influenced by smoking: Contribution of exogenous versus endogenous carcinogens
    • Wallerand H., Bakkar A.A., de Medina S.G., et al. Mutations in TP53, but not FGFR3, in urothelial cell carcinoma of the bladder are influenced by smoking: Contribution of exogenous versus endogenous carcinogens. Carcinogenesis 26 (2005) 177-184
    • (2005) Carcinogenesis , vol.26 , pp. 177-184
    • Wallerand, H.1    Bakkar, A.A.2    de Medina, S.G.3
  • 19
    • 33747079040 scopus 로고    scopus 로고
    • Prospective study of FGFR3 mutations as a prognostic factor in non-muscle-invasive urothelial bladder carcinomas
    • Hernandez S., Lopez-Knowles E., Lloreta J., et al. Prospective study of FGFR3 mutations as a prognostic factor in non-muscle-invasive urothelial bladder carcinomas. J Clin Oncol 24 (2006) 3664-3671
    • (2006) J Clin Oncol , vol.24 , pp. 3664-3671
    • Hernandez, S.1    Lopez-Knowles, E.2    Lloreta, J.3
  • 20
    • 33751024894 scopus 로고    scopus 로고
    • Molecular profiling of bladder tumors based on the detection of FGFR3 and TP53 mutations
    • Lamy A., Gobet F., Laurent M., et al. Molecular profiling of bladder tumors based on the detection of FGFR3 and TP53 mutations. J Urol 176 (2006) 2686-2689
    • (2006) J Urol , vol.176 , pp. 2686-2689
    • Lamy, A.1    Gobet, F.2    Laurent, M.3
  • 21
    • 23444440484 scopus 로고    scopus 로고
    • FGFR3 and Ras gene mutations are mutually exclusive genetic events in urothelial cell carcinoma
    • Jebar A.H., Hurst C.D., Tomlinson D.C., et al. FGFR3 and Ras gene mutations are mutually exclusive genetic events in urothelial cell carcinoma. Oncogene 24 (2005) 5218-5225
    • (2005) Oncogene , vol.24 , pp. 5218-5225
    • Jebar, A.H.1    Hurst, C.D.2    Tomlinson, D.C.3
  • 22
    • 33646359953 scopus 로고    scopus 로고
    • Molecular characterization of early-stage bladder carcinomas by expression profiles, FGFR3 mutation status, and loss of 9q
    • Lindgren D., Liedberg F., Andersson A., et al. Molecular characterization of early-stage bladder carcinomas by expression profiles, FGFR3 mutation status, and loss of 9q. Oncogene 25 (2006) 2685-2696
    • (2006) Oncogene , vol.25 , pp. 2685-2696
    • Lindgren, D.1    Liedberg, F.2    Andersson, A.3
  • 24
    • 34548407864 scopus 로고    scopus 로고
    • FGFR3 protein expression and its relationship to mutation status and prognostic variables in bladder cancer
    • Tomlinson D., Baldo O., and Knowles M.A. FGFR3 protein expression and its relationship to mutation status and prognostic variables in bladder cancer. J Pathol 213 (2007) 91-98
    • (2007) J Pathol , vol.213 , pp. 91-98
    • Tomlinson, D.1    Baldo, O.2    Knowles, M.A.3
  • 25
    • 16544376302 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 3 protein expression in urothelial carcinoma of the urinary bladder, exhibiting no association with low-grade and/or noninvasive lesions
    • Matsumoto M., Ohtsuki Y., Ochii K., et al. Fibroblast growth factor receptor 3 protein expression in urothelial carcinoma of the urinary bladder, exhibiting no association with low-grade and/or noninvasive lesions. Oncol Rep 12 (2004) 967-971
    • (2004) Oncol Rep , vol.12 , pp. 967-971
    • Matsumoto, M.1    Ohtsuki, Y.2    Ochii, K.3
  • 26
    • 32944481619 scopus 로고    scopus 로고
    • FGFR3 and p53 protein expressions in patients with pTa and pT1 urothelial bladder cancer
    • Mhawech-Fauceglia P., Cheney R.T., Fischer G., et al. FGFR3 and p53 protein expressions in patients with pTa and pT1 urothelial bladder cancer. Eur J Surg Oncol 32 (2006) 231-237
    • (2006) Eur J Surg Oncol , vol.32 , pp. 231-237
    • Mhawech-Fauceglia, P.1    Cheney, R.T.2    Fischer, G.3
  • 27
    • 19944426549 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 3 is overexpressed in urinary tract carcinomas and modulates the neoplastic cell growth
    • Gomez-Roman J.J., Saenz P., Molina M., et al. Fibroblast growth factor receptor 3 is overexpressed in urinary tract carcinomas and modulates the neoplastic cell growth. Clin Cancer Res 11 (2005) 459-465
    • (2005) Clin Cancer Res , vol.11 , pp. 459-465
    • Gomez-Roman, J.J.1    Saenz, P.2    Molina, M.3
  • 28
    • 33645288557 scopus 로고    scopus 로고
    • Oncogenic properties of the mutated forms of fibroblast growth factor receptor 3b
    • Bernard-Pierrot I., Brams A., Dunois-Larde C., et al. Oncogenic properties of the mutated forms of fibroblast growth factor receptor 3b. Carcinogenesis 27 (2006) 740-747
    • (2006) Carcinogenesis , vol.27 , pp. 740-747
    • Bernard-Pierrot, I.1    Brams, A.2    Dunois-Larde, C.3
  • 29
    • 24344461320 scopus 로고    scopus 로고
    • Targeting the extracellular domain of fibroblast growth factor receptor 3 with human single-chain fv antibodies inhibits bladder carcinoma cell line proliferation
    • Martinez-Torrecuadrada J., Cifuentes G., Lopez-Serra P., et al. Targeting the extracellular domain of fibroblast growth factor receptor 3 with human single-chain fv antibodies inhibits bladder carcinoma cell line proliferation. Clin Cancer Res 11 (2005) 6280-6290
    • (2005) Clin Cancer Res , vol.11 , pp. 6280-6290
    • Martinez-Torrecuadrada, J.1    Cifuentes, G.2    Lopez-Serra, P.3
  • 30
    • 0034612592 scopus 로고    scopus 로고
    • Transformation and Stat activation by derivatives of FGFR1, FGFR3, and FGFR4
    • Hart K.C., Robertson S.C., Kanemitsu M.Y., et al. Transformation and Stat activation by derivatives of FGFR1, FGFR3, and FGFR4. Oncogene 19 (2000) 3309-3320
    • (2000) Oncogene , vol.19 , pp. 3309-3320
    • Hart, K.C.1    Robertson, S.C.2    Kanemitsu, M.Y.3
  • 31
    • 33747873545 scopus 로고    scopus 로고
    • PIK3CA mutations are an early genetic alteration associated with FGFR3 mutations in superficial papillary bladder tumors
    • Lopez-Knowles E., Hernandez S., Malats N., et al. PIK3CA mutations are an early genetic alteration associated with FGFR3 mutations in superficial papillary bladder tumors. Cancer Res 66 (2006) 7401-7404
    • (2006) Cancer Res , vol.66 , pp. 7401-7404
    • Lopez-Knowles, E.1    Hernandez, S.2    Malats, N.3
  • 32
    • 70349667473 scopus 로고    scopus 로고
    • Spectrum of phosphatidylinositol 3-kinase pathway gene alterations in bladder cancer
    • Platt F.M., Hurst C.D., Taylor C.F., et al. Spectrum of phosphatidylinositol 3-kinase pathway gene alterations in bladder cancer. Clin Cancer Res 15 (2009) 6008-6017
    • (2009) Clin Cancer Res , vol.15 , pp. 6008-6017
    • Platt, F.M.1    Hurst, C.D.2    Taylor, C.F.3
  • 33
    • 70350064529 scopus 로고    scopus 로고
    • A SNaPshot assay for the rapid and simple detection of 4 common hotspot codon mutations in the PIK3CA gene
    • Hurst C.D., Zuiverloon T.C., Hafner C., et al. A SNaPshot assay for the rapid and simple detection of 4 common hotspot codon mutations in the PIK3CA gene. BMC Research Notes 2 (2009) 66
    • (2009) BMC Research Notes , vol.2 , pp. 66
    • Hurst, C.D.1    Zuiverloon, T.C.2    Hafner, C.3
  • 34
    • 70349763010 scopus 로고    scopus 로고
    • Identification of a region required for TSC1 stability by functional analysis of TSC1 missense mutations found in individuals with tuberous sclerosis complex
    • Mozaffari M., Hoogeveen-Westerveld M., Kwiatkowski D., et al. Identification of a region required for TSC1 stability by functional analysis of TSC1 missense mutations found in individuals with tuberous sclerosis complex. BMC Medical Genetic 10 (2009) 88
    • (2009) BMC Medical Genetic , vol.10 , pp. 88
    • Mozaffari, M.1    Hoogeveen-Westerveld, M.2    Kwiatkowski, D.3
  • 35
    • 60749128661 scopus 로고    scopus 로고
    • Missense mutations to the TSC1 gene cause tuberous sclerosis complex
    • Nellist M., van den Heuvel D., Schluep D., et al. Missense mutations to the TSC1 gene cause tuberous sclerosis complex. Eur J Human Genet 17 (2009) 319-328
    • (2009) Eur J Human Genet , vol.17 , pp. 319-328
    • Nellist, M.1    van den Heuvel, D.2    Schluep, D.3
  • 36
    • 0029831886 scopus 로고    scopus 로고
    • Allelic loss is frequent in tuberous sclerosis kidney lesions but rare in brain lesions
    • Henske E.P., Scheithauer B.W., Short M.P., et al. Allelic loss is frequent in tuberous sclerosis kidney lesions but rare in brain lesions. Am J Human Genet 59 (1996) 400-406
    • (1996) Am J Human Genet , vol.59 , pp. 400-406
    • Henske, E.P.1    Scheithauer, B.W.2    Short, M.P.3
  • 37
    • 0033594396 scopus 로고    scopus 로고
    • Mutation of the 9q34 gene TSC1 in sporadic bladder cancer
    • Hornigold N., Devlin J., Davies A.M., et al. Mutation of the 9q34 gene TSC1 in sporadic bladder cancer. Oncogene 18 (1999) 2657-2661
    • (1999) Oncogene , vol.18 , pp. 2657-2661
    • Hornigold, N.1    Devlin, J.2    Davies, A.M.3
  • 38
    • 0038507192 scopus 로고    scopus 로고
    • Human bladder tumors with 2-hit mutations of tumor suppressor gene TSC1 and decreased expression of p27
    • Adachi H., Igawa M., Shiina H., et al. Human bladder tumors with 2-hit mutations of tumor suppressor gene TSC1 and decreased expression of p27. J of Urol 170 (2003) 601-604
    • (2003) J of Urol , vol.170 , pp. 601-604
    • Adachi, H.1    Igawa, M.2    Shiina, H.3
  • 39
    • 0027516042 scopus 로고
    • Initiation of bladder cancer may involve deletion of a tumor-suppressor gene on chromosome 9
    • Cairns P., Shaw M.E., and Knowles M.A. Initiation of bladder cancer may involve deletion of a tumor-suppressor gene on chromosome 9. Oncogene 8 (1993) 1083-1085
    • (1993) Oncogene , vol.8 , pp. 1083-1085
    • Cairns, P.1    Shaw, M.E.2    Knowles, M.A.3
  • 40
    • 0028826489 scopus 로고
    • Detailed deletion mapping of chromosome 9q in bladder cancer: Evidence for 2 tumor suppressor loci
    • Habuchi T., Devlin J., Elder P.A., et al. Detailed deletion mapping of chromosome 9q in bladder cancer: Evidence for 2 tumor suppressor loci. Oncogene 11 (1995) 1671-1674
    • (1995) Oncogene , vol.11 , pp. 1671-1674
    • Habuchi, T.1    Devlin, J.2    Elder, P.A.3
  • 41
    • 0033531270 scopus 로고    scopus 로고
    • Four tumor suppressor loci on chromosome 9q in bladder cancer: Evidence for 2 novel candidate regions at 9q22.3 and 9q31
    • Simoneau M., Aboulkassim T.O., LaRue H., et al. Four tumor suppressor loci on chromosome 9q in bladder cancer: Evidence for 2 novel candidate regions at 9q22.3 and 9q31. Oncogene 18 (1999) 157-163
    • (1999) Oncogene , vol.18 , pp. 157-163
    • Simoneau, M.1    Aboulkassim, T.O.2    LaRue, H.3
  • 42
    • 0006181622 scopus 로고    scopus 로고
    • Evidence for 2 candidate tumor suppressor loci on chromosome 9q in transitional cell carcinoma (TCC) of the bladder but no homozygous deletions in bladder tumor cell lines
    • van Tilborg A.A., Groenfeld L.E., van der Kwast T.H., et al. Evidence for 2 candidate tumor suppressor loci on chromosome 9q in transitional cell carcinoma (TCC) of the bladder but no homozygous deletions in bladder tumor cell lines. Br J Cancer 80 (1999) 489-494
    • (1999) Br J Cancer , vol.80 , pp. 489-494
    • van Tilborg, A.A.1    Groenfeld, L.E.2    van der Kwast, T.H.3
  • 43
    • 0345707579 scopus 로고    scopus 로고
    • Mutation spectrum of the 9q34 tuberous sclerosis gene TSC1 in transitional cell carcinoma of the bladder
    • Knowles M.A., Habuchi T., Kennedy W., et al. Mutation spectrum of the 9q34 tuberous sclerosis gene TSC1 in transitional cell carcinoma of the bladder. Cancer Res 63 (2003) 7652-7656
    • (2003) Cancer Res , vol.63 , pp. 7652-7656
    • Knowles, M.A.1    Habuchi, T.2    Kennedy, W.3
  • 44
    • 45749119969 scopus 로고    scopus 로고
    • Bladder tumor derived somatic TSC1 missense mutations cause loss of function via distinct mechanisms
    • Pymar L.S., Platt F.M., Askham J.M., et al. Bladder tumor derived somatic TSC1 missense mutations cause loss of function via distinct mechanisms. Human Molecular Genetics 17 (2008) 2006-2017
    • (2008) Human Molecular Genetics , vol.17 , pp. 2006-2017
    • Pymar, L.S.1    Platt, F.M.2    Askham, J.M.3
  • 45
    • 34547172596 scopus 로고    scopus 로고
    • A transforming mutation in the Pleckstrin homology domain of AKT1 in cancer
    • Carpten J.D., Faber A.L., Horn C., et al. A transforming mutation in the Pleckstrin homology domain of AKT1 in cancer. Nature 448 (2007) 439-444
    • (2007) Nature , vol.448 , pp. 439-444
    • Carpten, J.D.1    Faber, A.L.2    Horn, C.3
  • 46
    • 73849134249 scopus 로고    scopus 로고
    • AKT1 mutations in bladder cancer: Identification of a novel oncogenic mutation that can cooperate with E17K
    • Askham J.M., Platt F., Chambers P.A., et al. AKT1 mutations in bladder cancer: Identification of a novel oncogenic mutation that can cooperate with E17K. Oncogene 29 (2010) 150-155
    • (2010) Oncogene , vol.29 , pp. 150-155
    • Askham, J.M.1    Platt, F.2    Chambers, P.A.3
  • 47
    • 0036791498 scopus 로고    scopus 로고
    • Identification of chromosome 9 alterations and p53 accumulation in isolated carcinoma in situ of the urinary bladder versus carcinoma in situ associated with carcinoma
    • Hopman A.H., Kamps M.A., Speel E.J., et al. Identification of chromosome 9 alterations and p53 accumulation in isolated carcinoma in situ of the urinary bladder versus carcinoma in situ associated with carcinoma. Am J Pathol 161 (2002) 1119-1125
    • (2002) Am J Pathol , vol.161 , pp. 1119-1125
    • Hopman, A.H.1    Kamps, M.A.2    Speel, E.J.3
  • 48
    • 0036468296 scopus 로고    scopus 로고
    • Occurrence of chromosome 9 and p53 alterations in multifocal dysplasia and carcinoma in situ of human urinary bladder
    • Hartmann A., Schlake G., Zaak D., et al. Occurrence of chromosome 9 and p53 alterations in multifocal dysplasia and carcinoma in situ of human urinary bladder. Cancer Res 62 (2002) 809-818
    • (2002) Cancer Res , vol.62 , pp. 809-818
    • Hartmann, A.1    Schlake, G.2    Zaak, D.3
  • 49
    • 0028849278 scopus 로고
    • Partial allelotype of carcinoma in situ of the human bladder
    • Rosin M.P., Cairns P., Epstein J.I., et al. Partial allelotype of carcinoma in situ of the human bladder. Cancer Res 55 (1995) 5213-5216
    • (1995) Cancer Res , vol.55 , pp. 5213-5216
    • Rosin, M.P.1    Cairns, P.2    Epstein, J.I.3
  • 50
    • 0028036255 scopus 로고
    • Two molecular pathways to transitional cell carcinoma of the bladder
    • Spruck III C.H., Ohneseit P.F., Gonzalez-Zulueta M., et al. Two molecular pathways to transitional cell carcinoma of the bladder. Cancer Res 54 (1994) 784-788
    • (1994) Cancer Res , vol.54 , pp. 784-788
    • Spruck III, C.H.1    Ohneseit, P.F.2    Gonzalez-Zulueta, M.3
  • 51
    • 38649119486 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 3 mutations in bladder tumors correlate with low frequency of chromosome alterations
    • Junker K., van Oers J.M., Zwarthoff E.C., et al. Fibroblast growth factor receptor 3 mutations in bladder tumors correlate with low frequency of chromosome alterations. Neoplasia 10 (2008) 1-7
    • (2008) Neoplasia , vol.10 , pp. 1-7
    • Junker, K.1    van Oers, J.M.2    Zwarthoff, E.C.3
  • 52
    • 2542565666 scopus 로고    scopus 로고
    • Gene expression in the urinary bladder: A common carcinoma in situ gene expression signature exists disregarding histopathological classification
    • Dyrskjot L., Kruhoffer M., Thykjaer T., et al. Gene expression in the urinary bladder: A common carcinoma in situ gene expression signature exists disregarding histopathological classification. Cancer Res 64 (2004) 4040-4048
    • (2004) Cancer Res , vol.64 , pp. 4040-4048
    • Dyrskjot, L.1    Kruhoffer, M.2    Thykjaer, T.3
  • 53
    • 20344387231 scopus 로고    scopus 로고
    • A molecular signature in superficial bladder carcinoma predicts clinical outcome
    • Dyrskjot L., Zieger K., Kruhoffer M., et al. A molecular signature in superficial bladder carcinoma predicts clinical outcome. Clin Cancer Res 11 (2005) 4029-4036
    • (2005) Clin Cancer Res , vol.11 , pp. 4029-4036
    • Dyrskjot, L.1    Zieger, K.2    Kruhoffer, M.3
  • 54
    • 34250738489 scopus 로고    scopus 로고
    • Gene expression signatures predict outcome in non-muscle-invasive bladder carcinoma: A multicenter validation study
    • Dyrskjot L., Zieger K., Real F.X., et al. Gene expression signatures predict outcome in non-muscle-invasive bladder carcinoma: A multicenter validation study. Clin Cancer Res 13 (2007) 3545-3551
    • (2007) Clin Cancer Res , vol.13 , pp. 3545-3551
    • Dyrskjot, L.1    Zieger, K.2    Real, F.X.3
  • 55
    • 27744515561 scopus 로고    scopus 로고
    • Role of activating fibroblast growth factor receptor 3 mutations in the development of bladder tumors
    • Zieger K., Dyrskjøt L., Wiuf C., et al. Role of activating fibroblast growth factor receptor 3 mutations in the development of bladder tumors. Clin Cancer Res 11 (2005) 7709-7719
    • (2005) Clin Cancer Res , vol.11 , pp. 7709-7719
    • Zieger, K.1    Dyrskjøt, L.2    Wiuf, C.3
  • 56
    • 70249110104 scopus 로고    scopus 로고
    • Consistent genomic alterations in carcinoma in situ of the urinary bladder confirm the presence of 2 major pathways in bladder cancer development
    • Zieger K., Marcussen N., Borre M., et al. Consistent genomic alterations in carcinoma in situ of the urinary bladder confirm the presence of 2 major pathways in bladder cancer development. Int J Cancer. 1 125 (2009) 2095-2103
    • (2009) Int J Cancer. 1 , vol.125 , pp. 2095-2103
    • Zieger, K.1    Marcussen, N.2    Borre, M.3
  • 57
    • 0026504931 scopus 로고
    • Frequent association of p53 gene mutation in invasive bladder cancer
    • Fujimoto K., Yamada Y., Okajima E., et al. Frequent association of p53 gene mutation in invasive bladder cancer. Cancer Res 52 (1992) 1393-1398
    • (1992) Cancer Res , vol.52 , pp. 1393-1398
    • Fujimoto, K.1    Yamada, Y.2    Okajima, E.3
  • 58
    • 0028911774 scopus 로고
    • p53 mutations and prognosis in bladder tumors
    • Uchida T., Wada C., Ishida H., et al. p53 mutations and prognosis in bladder tumors. J Urol 153 (1995) 1097-1104
    • (1995) J Urol , vol.153 , pp. 1097-1104
    • Uchida, T.1    Wada, C.2    Ishida, H.3
  • 59
    • 34047207337 scopus 로고    scopus 로고
    • TP53 mutations in human cancers: Functional selection and impact on cancer prognosis and outcomes
    • Petitjean A., Achatz M.I.W., Borresen-Dale A.L., et al. TP53 mutations in human cancers: Functional selection and impact on cancer prognosis and outcomes. Oncogene 26 (2007) 2157-2165
    • (2007) Oncogene , vol.26 , pp. 2157-2165
    • Petitjean, A.1    Achatz, M.I.W.2    Borresen-Dale, A.L.3
  • 60
    • 0035751937 scopus 로고    scopus 로고
    • Assessing TP53 status in human tumors to evaluate clinical outcome
    • Soussi T., and Beroud C. Assessing TP53 status in human tumors to evaluate clinical outcome. Nat Rev Cancer 1 (2001) 233-240
    • (2001) Nat Rev Cancer , vol.1 , pp. 233-240
    • Soussi, T.1    Beroud, C.2
  • 61
    • 0036258111 scopus 로고    scopus 로고
    • The IARC TP53 database: New online mutation analysis and recommendations to users
    • Olivier M., Eeles R., Hollstein M., et al. The IARC TP53 database: New online mutation analysis and recommendations to users. Hum Mutat 19 (2002) 607-614
    • (2002) Hum Mutat , vol.19 , pp. 607-614
    • Olivier, M.1    Eeles, R.2    Hollstein, M.3
  • 62
    • 0033552948 scopus 로고    scopus 로고
    • Mutant p53 gain of function: Differential effects of different p53 mutants on resistance of cultured cells to chemotherapy
    • Blandino G., Levine A.J., and Oren M. Mutant p53 gain of function: Differential effects of different p53 mutants on resistance of cultured cells to chemotherapy. Oncogene 18 (1999) 477-485
    • (1999) Oncogene , vol.18 , pp. 477-485
    • Blandino, G.1    Levine, A.J.2    Oren, M.3
  • 63
    • 34047198167 scopus 로고    scopus 로고
    • Transcription regulation by mutant p53
    • Weisz L., Oren M., and Rotter V. Transcription regulation by mutant p53. Oncogene 26 (2007) 2202-2211
    • (2007) Oncogene , vol.26 , pp. 2202-2211
    • Weisz, L.1    Oren, M.2    Rotter, V.3
  • 64
    • 34047205431 scopus 로고    scopus 로고
    • Mutant p53: An oncogenic transcription factor
    • Strano S., Dell'Orso S., Di Agostino S., et al. Mutant p53: An oncogenic transcription factor. Oncogene 26 (2007) 2212-2219
    • (2007) Oncogene , vol.26 , pp. 2212-2219
    • Strano, S.1    Dell'Orso, S.2    Di Agostino, S.3
  • 65
    • 34047216406 scopus 로고    scopus 로고
    • p53 alterations in human cancer: More questions than answers
    • Soussi T. p53 alterations in human cancer: More questions than answers. Oncogene 26 (2007) 2145-2156
    • (2007) Oncogene , vol.26 , pp. 2145-2156
    • Soussi, T.1
  • 66
    • 3342942698 scopus 로고    scopus 로고
    • Bladder cancer and P53: An example of what should not be done in biomarker research
    • Malats N., Kogevinas M., Bustos A., et al. Bladder cancer and P53: An example of what should not be done in biomarker research. Int J Biol Markers 15 (2000) S30
    • (2000) Int J Biol Markers , vol.15
    • Malats, N.1    Kogevinas, M.2    Bustos, A.3
  • 67
    • 0033673208 scopus 로고    scopus 로고
    • P53 immunohistochemistry as a prognostic marker in bladder cancer: A new toy for urologic scientists?
    • Schmitz-Dräger B.J., Goebell P.J., Ebert T., et al. P53 immunohistochemistry as a prognostic marker in bladder cancer: A new toy for urologic scientists?. Eur Urol 38 (2000) 691-700
    • (2000) Eur Urol , vol.38 , pp. 691-700
    • Schmitz-Dräger, B.J.1    Goebell, P.J.2    Ebert, T.3
  • 68
    • 0033951911 scopus 로고    scopus 로고
    • Biological markers in superficial bladder tumors and their prognostic significance
    • Zlotta A.R., and Schulman C.C. Biological markers in superficial bladder tumors and their prognostic significance. Urol Clin North Am 27 (2000) 179-189
    • (2000) Urol Clin North Am , vol.27 , pp. 179-189
    • Zlotta, A.R.1    Schulman, C.C.2
  • 69
    • 84925559801 scopus 로고    scopus 로고
    • A critical look at Antigen Retrieval and Choice of Antibodies for p53 Immunohistochemistry - Technical Aspects in the ISBC Combined Analysis
    • The International Study Initiative on Bladder Cancer (ISBC)
    • Goebell P.J., Schmitz-Dräger B.J., Heydthausen M., et al., The International Study Initiative on Bladder Cancer (ISBC). A critical look at Antigen Retrieval and Choice of Antibodies for p53 Immunohistochemistry - Technical Aspects in the ISBC Combined Analysis. J Urol 167 (2002) 453
    • (2002) J Urol , vol.167 , pp. 453
    • Goebell, P.J.1    Schmitz-Dräger, B.J.2    Heydthausen, M.3
  • 70
    • 0028340464 scopus 로고
    • The immunocytochemical detection of p53 protein in cytological specimens: Technical considerations
    • Dowell S.P., Lane D.P., and Hall P.A. The immunocytochemical detection of p53 protein in cytological specimens: Technical considerations. Cytopathology 5 (1994) 76-81
    • (1994) Cytopathology , vol.5 , pp. 76-81
    • Dowell, S.P.1    Lane, D.P.2    Hall, P.A.3
  • 71
    • 24044554230 scopus 로고    scopus 로고
    • P53 as a prognostic marker for bladder cancer: A meta-analysis and review
    • Malats N., Bustos A., Nascimento C.M., et al. P53 as a prognostic marker for bladder cancer: A meta-analysis and review. Lancet Oncol 6 (2005) 678-686
    • (2005) Lancet Oncol , vol.6 , pp. 678-686
    • Malats, N.1    Bustos, A.2    Nascimento, C.M.3
  • 72
    • 0342484451 scopus 로고    scopus 로고
    • P53 immunohistochemistry in bladder cancer. Combined analysis: A way to go?
    • The International Study Initiative on Bladder Cancer (ISBC)
    • Schmitz-Dräger B.J., Goebell P.J., Heydthausen M., and The International Study Initiative on Bladder Cancer (ISBC). P53 immunohistochemistry in bladder cancer. Combined analysis: A way to go?. Urol Oncol 5 (2000) 204-215
    • (2000) Urol Oncol , vol.5 , pp. 204-215
    • Schmitz-Dräger, B.J.1    Goebell, P.J.2    Heydthausen, M.3
  • 73
    • 77953815362 scopus 로고    scopus 로고
    • P53 Immunohistochemistry in Bladder Cancer - a new approach to an old story
    • Goebell P.J., Groshen S.G., and Schmitz-Dräger B.J. P53 Immunohistochemistry in Bladder Cancer - a new approach to an old story. Urol Oncol 28 (2010) 377-388
    • (2010) Urol Oncol , vol.28 , pp. 377-388
    • Goebell, P.J.1    Groshen, S.G.2    Schmitz-Dräger, B.J.3
  • 74
    • 0028299342 scopus 로고
    • p53 in tumor pathology: Can we trust immunohistochemistry?
    • Hall P.A., and Lane D.P. p53 in tumor pathology: Can we trust immunohistochemistry?. Revisited! J Pathol 172 (1994) 1-4
    • (1994) Revisited! J Pathol , vol.172 , pp. 1-4
    • Hall, P.A.1    Lane, D.P.2
  • 75
    • 36849076630 scopus 로고    scopus 로고
    • p53 gene and protein status: The role of p53 alterations in predicting outcome in patients with bladder cancer
    • George B., Datar R.H., Wu L., et al. p53 gene and protein status: The role of p53 alterations in predicting outcome in patients with bladder cancer. J Clin Oncol 25 (2007) 5352-5358
    • (2007) J Clin Oncol , vol.25 , pp. 5352-5358
    • George, B.1    Datar, R.H.2    Wu, L.3
  • 76
    • 2442616818 scopus 로고    scopus 로고
    • A population-based study of Immunohistochemical detection of p53 alteration in bladder cancer
    • Kelsey K.T., Hirao T., Schned A., et al. A population-based study of Immunohistochemical detection of p53 alteration in bladder cancer. Br J Cancer 90 (2004) 1572-1576
    • (2004) Br J Cancer , vol.90 , pp. 1572-1576
    • Kelsey, K.T.1    Hirao, T.2    Schned, A.3
  • 77
    • 33750724743 scopus 로고    scopus 로고
    • The p53 pathway and outcome among patients with T1G3 bladder tumors
    • Lopez-Knowles E., Hernandez S., Kogevinas M., et al. The p53 pathway and outcome among patients with T1G3 bladder tumors. Clin Cancer Res 12 (2006) 6029-6036
    • (2006) Clin Cancer Res , vol.12 , pp. 6029-6036
    • Lopez-Knowles, E.1    Hernandez, S.2    Kogevinas, M.3
  • 78
    • 85047697635 scopus 로고    scopus 로고
    • Amplification pattern of 12q13 q15 genes (MDM2, CDK4, GLI) in urinary bladder cancer
    • Simon R., Struckmann K., Schraml P., et al. Amplification pattern of 12q13 q15 genes (MDM2, CDK4, GLI) in urinary bladder cancer. Oncogene 21 (2002) 2476-2483
    • (2002) Oncogene , vol.21 , pp. 2476-2483
    • Simon, R.1    Struckmann, K.2    Schraml, P.3
  • 79
    • 4143078094 scopus 로고    scopus 로고
    • Genomic organization of the human MDM2 oncogene and relationship to its alternatively spliced mRNAs
    • Liang H., Atkins H., Abdel-Fattah R., et al. Genomic organization of the human MDM2 oncogene and relationship to its alternatively spliced mRNAs. Gene 338 (2004) 217-223
    • (2004) Gene , vol.338 , pp. 217-223
    • Liang, H.1    Atkins, H.2    Abdel-Fattah, R.3
  • 80
    • 21644472899 scopus 로고    scopus 로고
    • Alteration of the MDM2-p73-P14ARF pathway related to tumor progression during urinary bladder carcinogenesis
    • Schlott T., Quentin T., Korabiowska M., et al. Alteration of the MDM2-p73-P14ARF pathway related to tumor progression during urinary bladder carcinogenesis. Int J Mol Med 14 (2004) 825-836
    • (2004) Int J Mol Med , vol.14 , pp. 825-836
    • Schlott, T.1    Quentin, T.2    Korabiowska, M.3
  • 81
    • 34250648071 scopus 로고    scopus 로고
    • A polymorphism in HDM2 (SNP309) associates with early onset in superficial tumors, TP53 mutations, and poor outcome in invasive bladder cancer
    • Sanchez-Carbayo M., Socci N.D., Kirchoff T., et al. A polymorphism in HDM2 (SNP309) associates with early onset in superficial tumors, TP53 mutations, and poor outcome in invasive bladder cancer. Clin Cancer Res 13 (2007) 3215-3220
    • (2007) Clin Cancer Res , vol.13 , pp. 3215-3220
    • Sanchez-Carbayo, M.1    Socci, N.D.2    Kirchoff, T.3
  • 82
    • 0032403183 scopus 로고    scopus 로고
    • Presence and location of TP53 mutation determines pattern of CDKN2A/ARF pathway inactivation in bladder cancer
    • Markl I.D., and Jones P.A. Presence and location of TP53 mutation determines pattern of CDKN2A/ARF pathway inactivation in bladder cancer. Cancer Res 58 (1998) 5348-5353
    • (1998) Cancer Res , vol.58 , pp. 5348-5353
    • Markl, I.D.1    Jones, P.A.2
  • 83
    • 0038507189 scopus 로고    scopus 로고
    • Genetic alterations of p16INK4a and p14ARF genes in human bladder cancer
    • Chang L.L., Yeh W.T., Yang S.Y., et al. Genetic alterations of p16INK4a and p14ARF genes in human bladder cancer. J Urol 170 (2003) 595-600
    • (2003) J Urol , vol.170 , pp. 595-600
    • Chang, L.L.1    Yeh, W.T.2    Yang, S.Y.3
  • 84
    • 12244264803 scopus 로고    scopus 로고
    • Detecting homozygous deletions in the CDKN2A(p16(INK4a))/ARF(p14(ARF)) gene in urinary bladder cancer using real-time quantitative PCR
    • Berggren P., Kumar R., Sakano S., et al. Detecting homozygous deletions in the CDKN2A(p16(INK4a))/ARF(p14(ARF)) gene in urinary bladder cancer using real-time quantitative PCR. Clin Cancer Res 9 (2003) 235-242
    • (2003) Clin Cancer Res , vol.9 , pp. 235-242
    • Berggren, P.1    Kumar, R.2    Sakano, S.3
  • 85
    • 3142606708 scopus 로고    scopus 로고
    • Profiles of the 2 INK4a gene products, p16 and p14ARF, in human reference urothelium and bladder carcinomas, according to pRb and p53 protein status
    • Le Frère-Belda M.A., Gil Diez de Medina S., Daher A., et al. Profiles of the 2 INK4a gene products, p16 and p14ARF, in human reference urothelium and bladder carcinomas, according to pRb and p53 protein status. Hum Pathol 35 (2004) 817-824
    • (2004) Hum Pathol , vol.35 , pp. 817-824
    • Le Frère-Belda, M.A.1    Gil Diez de Medina, S.2    Daher, A.3
  • 86
    • 28844461573 scopus 로고    scopus 로고
    • p16INK4a and p14ARF methylation as a potential biomarker for human bladder cancer
    • Kawamoto K., Enokida H., Gotanda T., et al. p16INK4a and p14ARF methylation as a potential biomarker for human bladder cancer. Biochem Biophys Res Commun 339 (2006) 790-796
    • (2006) Biochem Biophys Res Commun , vol.339 , pp. 790-796
    • Kawamoto, K.1    Enokida, H.2    Gotanda, T.3
  • 87
    • 0032527133 scopus 로고    scopus 로고
    • Effect of p21WAF1/CIP1 expression on tumor progression in bladder cancer
    • Stein J.P., Ginsberg D.A., Grossfeld G.D., et al. Effect of p21WAF1/CIP1 expression on tumor progression in bladder cancer. J Natl Cancer Inst 90 (1998) 1072-1079
    • (1998) J Natl Cancer Inst , vol.90 , pp. 1072-1079
    • Stein, J.P.1    Ginsberg, D.A.2    Grossfeld, G.D.3
  • 88
    • 1842509884 scopus 로고    scopus 로고
    • Combined effects of p53, p21, and pRb expression in the progression of bladder transitional cell carcinoma
    • Chatterjee S.J., Datar R., Youssefzadeh D., et al. Combined effects of p53, p21, and pRb expression in the progression of bladder transitional cell carcinoma. J Clin Oncol 22 (2004) 1007-1013
    • (2004) J Clin Oncol , vol.22 , pp. 1007-1013
    • Chatterjee, S.J.1    Datar, R.2    Youssefzadeh, D.3
  • 89
    • 71249096845 scopus 로고    scopus 로고
    • Combination of multiple molecular markers can improve prognostication in patients with locally advanced and lymph node positive bladder cancer
    • Shariat S.F., Chade D.C., Karakiewicz P.I., et al. Combination of multiple molecular markers can improve prognostication in patients with locally advanced and lymph node positive bladder cancer. J Urol 183 (2010) 68-75
    • (2010) J Urol , vol.183 , pp. 68-75
    • Shariat, S.F.1    Chade, D.C.2    Karakiewicz, P.I.3
  • 90
    • 0026335819 scopus 로고
    • Loss of heterozygosity at the RB locus is frequent and correlates with muscle invasion in bladder carcinoma
    • Cairns P., Proctor A.J., and Knowles M.A. Loss of heterozygosity at the RB locus is frequent and correlates with muscle invasion in bladder carcinoma. Oncogene 6 (1991) 2305-2309
    • (1991) Oncogene , vol.6 , pp. 2305-2309
    • Cairns, P.1    Proctor, A.J.2    Knowles, M.A.3
  • 91
    • 0033521887 scopus 로고    scopus 로고
    • Level of retinoblastoma protein expression correlates with p16 (MTS-1/INK4A/CDKN2) status in bladder cancer
    • Benedict W.F., Lerner S.P., Zhou J., et al. Level of retinoblastoma protein expression correlates with p16 (MTS-1/INK4A/CDKN2) status in bladder cancer. Oncogene 18 (1999) 1197-1203
    • (1999) Oncogene , vol.18 , pp. 1197-1203
    • Benedict, W.F.1    Lerner, S.P.2    Zhou, J.3
  • 92
    • 1842457693 scopus 로고    scopus 로고
    • p53, p21, pRB, and p16 expression predict clinical outcome in cystectomy with bladder cancer
    • Shariat S.F., Tokunaga H., and Zhou J. p53, p21, pRB, and p16 expression predict clinical outcome in cystectomy with bladder cancer. J Clin Oncol 22 (2004) 1014-1024
    • (2004) J Clin Oncol , vol.22 , pp. 1014-1024
    • Shariat, S.F.1    Tokunaga, H.2    Zhou, J.3
  • 93
    • 0026700568 scopus 로고
    • Altered expression of the retinoblastoma gene product: Prognostic indicator in bladder cancer
    • Cordon-Cardo C., Wartinger D., Petrylak D., et al. Altered expression of the retinoblastoma gene product: Prognostic indicator in bladder cancer. J Natl Cancer Inst 84 (1992) 1251-1256
    • (1992) J Natl Cancer Inst , vol.84 , pp. 1251-1256
    • Cordon-Cardo, C.1    Wartinger, D.2    Petrylak, D.3
  • 94
    • 0026673062 scopus 로고
    • Altered expression of retinoblastoma protein and known prognostic variables in locally advanced bladder cancer
    • Logothetis C.J., Xu H.-J., Ro J.Y., et al. Altered expression of retinoblastoma protein and known prognostic variables in locally advanced bladder cancer. J Natl Cancer Inst 84 (1992) 1256-1261
    • (1992) J Natl Cancer Inst , vol.84 , pp. 1256-1261
    • Logothetis, C.J.1    Xu, H.-J.2    Ro, J.Y.3
  • 95
    • 42549109141 scopus 로고    scopus 로고
    • Inactivation of the Rb pathway and overexpression of both isoforms of E2F3 are obligate events in bladder tumors with 6p22 amplification
    • Hurst C.D., Tomlinson D.C., Williams S.V., et al. Inactivation of the Rb pathway and overexpression of both isoforms of E2F3 are obligate events in bladder tumors with 6p22 amplification. Oncogene 27 (2008) 2716-2727
    • (2008) Oncogene , vol.27 , pp. 2716-2727
    • Hurst, C.D.1    Tomlinson, D.C.2    Williams, S.V.3
  • 96
    • 1542426648 scopus 로고    scopus 로고
    • Amplification and overexpression of E2F3 in human bladder cancer
    • Feber A., Clark J., Goodwin G., et al. Amplification and overexpression of E2F3 in human bladder cancer. Oncogene 23 (2004) 1627-1630
    • (2004) Oncogene , vol.23 , pp. 1627-1630
    • Feber, A.1    Clark, J.2    Goodwin, G.3
  • 97
    • 3342974830 scopus 로고    scopus 로고
    • E2F3 amplification and overexpression is associated with invasive tumor growth and rapid tumor cell proliferation in urinary bladder cancer
    • Oeggerli M., Tomovska S., Schraml P., et al. E2F3 amplification and overexpression is associated with invasive tumor growth and rapid tumor cell proliferation in urinary bladder cancer. Oncogene 23 (2004) 5616-5623
    • (2004) Oncogene , vol.23 , pp. 5616-5623
    • Oeggerli, M.1    Tomovska, S.2    Schraml, P.3
  • 98
    • 34249828965 scopus 로고    scopus 로고
    • A variant in CDKAL1 influences insulin response and risk of type 2 diabetes
    • Steinthorsdottir V., Thorleifsson G., Reynisdottir I., et al. A variant in CDKAL1 influences insulin response and risk of type 2 diabetes. Nat Genet 39 (2007) 770-775
    • (2007) Nat Genet , vol.39 , pp. 770-775
    • Steinthorsdottir, V.1    Thorleifsson, G.2    Reynisdottir, I.3
  • 99
    • 33750221102 scopus 로고    scopus 로고
    • E2F3 is the main target gene of the 6p22 amplicon with high specificity for human bladder cancer
    • Oeggerli M., Schraml P., Ruiz C., et al. E2F3 is the main target gene of the 6p22 amplicon with high specificity for human bladder cancer. Oncogene 25 (2006) 6538-6543
    • (2006) Oncogene , vol.25 , pp. 6538-6543
    • Oeggerli, M.1    Schraml, P.2    Ruiz, C.3
  • 100
    • 33847036611 scopus 로고    scopus 로고
    • Role of E2F3 expression in modulating cellular proliferation rate in human bladder and prostate cancer cells
    • Olsson A.Y., Feber A., Edwards S., et al. Role of E2F3 expression in modulating cellular proliferation rate in human bladder and prostate cancer cells. Oncogene 26 (2007) 1028-1037
    • (2007) Oncogene , vol.26 , pp. 1028-1037
    • Olsson, A.Y.1    Feber, A.2    Edwards, S.3
  • 101
    • 0027516618 scopus 로고
    • Loss of RB protein expression in primary bladder cancer correlates with loss of heterozygosity at the RB locus and tumor progression
    • Xu H.J., Cairns P., Hu S.X., et al. Loss of RB protein expression in primary bladder cancer correlates with loss of heterozygosity at the RB locus and tumor progression. Int J Cancer 53 (1993) 781-784
    • (1993) Int J Cancer , vol.53 , pp. 781-784
    • Xu, H.J.1    Cairns, P.2    Hu, S.X.3
  • 102
    • 11244266433 scopus 로고    scopus 로고
    • Loss of heterozygosity analysis and DNA copy number measurement on 8p in bladder cancer reveals 2 mechanisms of allelic loss
    • Adams J., Williams S.V., Aveyard J.S., et al. Loss of heterozygosity analysis and DNA copy number measurement on 8p in bladder cancer reveals 2 mechanisms of allelic loss. Cancer Res 65 (2005) 66-75
    • (2005) Cancer Res , vol.65 , pp. 66-75
    • Adams, J.1    Williams, S.V.2    Aveyard, J.S.3
  • 103
    • 0342859309 scopus 로고    scopus 로고
    • Loss of heterozygosity at chromosome segments 8p22 and 8p11.2 21.1 in transitional-cell carcinoma of the urinary bladder
    • Choi C., Kim M.H., Juhng S.W., et al. Loss of heterozygosity at chromosome segments 8p22 and 8p11.2 21.1 in transitional-cell carcinoma of the urinary bladder. Int J Cancer 86 (2000) 501-505
    • (2000) Int J Cancer , vol.86 , pp. 501-505
    • Choi, C.1    Kim, M.H.2    Juhng, S.W.3
  • 104
    • 2342574321 scopus 로고    scopus 로고
    • Deletions of chromosome 8p and loss of sFRP1 expression are progression markers of papillary bladder cancer
    • Stoehr R., Wissmann C., Suzuki H., et al. Deletions of chromosome 8p and loss of sFRP1 expression are progression markers of papillary bladder cancer. Lab Invest 16 (2004) 465-478
    • (2004) Lab Invest , vol.16 , pp. 465-478
    • Stoehr, R.1    Wissmann, C.2    Suzuki, H.3
  • 105
    • 0029966406 scopus 로고    scopus 로고
    • Deletion mapping implicates 2 tumor suppressor genes on chromosome 8p in the development of bladder cancer
    • Takle L.A., and Knowles M.A. Deletion mapping implicates 2 tumor suppressor genes on chromosome 8p in the development of bladder cancer. Oncogene 12 (1996) 1083-1087
    • (1996) Oncogene , vol.12 , pp. 1083-1087
    • Takle, L.A.1    Knowles, M.A.2
  • 106
    • 0036606302 scopus 로고    scopus 로고
    • Splice variants but not mutations of DNA polymerase beta are common in bladder cancer
    • Thompson T.E., Rogan P.K., Risinger J.I., et al. Splice variants but not mutations of DNA polymerase beta are common in bladder cancer. Cancer Res 62 (2002) 3251-3256
    • (2002) Cancer Res , vol.62 , pp. 3251-3256
    • Thompson, T.E.1    Rogan, P.K.2    Risinger, J.I.3
  • 107
    • 17644368572 scopus 로고    scopus 로고
    • Infrequent mutation of TRAIL receptor 2 (TRAIL-R2/DR5) in transitional cell carcinoma of the bladder with 8p21 loss of heterozygosity
    • Adams J., Cuthbert-Heavens D., Bass S., et al. Infrequent mutation of TRAIL receptor 2 (TRAIL-R2/DR5) in transitional cell carcinoma of the bladder with 8p21 loss of heterozygosity. Cancer Lett 220 (2005) 137-144
    • (2005) Cancer Lett , vol.220 , pp. 137-144
    • Adams, J.1    Cuthbert-Heavens, D.2    Bass, S.3
  • 108
    • 0030937872 scopus 로고    scopus 로고
    • Mutation analysis of 8p genes POLB and PPP2CB in bladder cancer
    • Eydmann M.E., and Knowles M.A. Mutation analysis of 8p genes POLB and PPP2CB in bladder cancer. Cancer Genet Cytogenet 93 (1997) 167-171
    • (1997) Cancer Genet Cytogenet , vol.93 , pp. 167-171
    • Eydmann, M.E.1    Knowles, M.A.2
  • 109
    • 19544366580 scopus 로고    scopus 로고
    • Mutation analysis of the 8p candidate tumor suppressor genes DBC2 (RHOBTB2) and LZTS1 in bladder cancer
    • Knowles M.A., Aveyard J.S., Taylor C.F., et al. Mutation analysis of the 8p candidate tumor suppressor genes DBC2 (RHOBTB2) and LZTS1 in bladder cancer. Cancer Lett 225 (2005) 121-130
    • (2005) Cancer Lett , vol.225 , pp. 121-130
    • Knowles, M.A.1    Aveyard, J.S.2    Taylor, C.F.3
  • 110
    • 26444453688 scopus 로고    scopus 로고
    • Bladder cancer stage and outcome by array-based comparative genomic hybridization
    • Blaveri E., Brewer J.L., Roydasgupta R., et al. Bladder cancer stage and outcome by array-based comparative genomic hybridization. Clin Cancer Res 11 (2005) 7012-7022
    • (2005) Clin Cancer Res , vol.11 , pp. 7012-7022
    • Blaveri, E.1    Brewer, J.L.2    Roydasgupta, R.3
  • 111
    • 0031794480 scopus 로고    scopus 로고
    • Patterns of chromosomal imbalances in advanced urinary bladder cancer detected by comparative genomic hybridization
    • Richter J., Beffa L., Wagner U., et al. Patterns of chromosomal imbalances in advanced urinary bladder cancer detected by comparative genomic hybridization. Am J Pathol 153 (1998) 1615-1621
    • (1998) Am J Pathol , vol.153 , pp. 1615-1621
    • Richter, J.1    Beffa, L.2    Wagner, U.3
  • 112
    • 0032897458 scopus 로고    scopus 로고
    • Somatic mutation of PTEN in bladder carcinoma
    • Aveyard J.S., Skilleter A., Habuchi T., et al. Somatic mutation of PTEN in bladder carcinoma. Br J Cancer 80 (1999) 904-908
    • (1999) Br J Cancer , vol.80 , pp. 904-908
    • Aveyard, J.S.1    Skilleter, A.2    Habuchi, T.3
  • 113
    • 8544237725 scopus 로고    scopus 로고
    • Frequent loss of heterozygosity on chromosome 10q in muscle-invasive transitional cell carcinomas of the bladder
    • Cappellen D., Gil Diez de Medina S., Chopin D., et al. Frequent loss of heterozygosity on chromosome 10q in muscle-invasive transitional cell carcinomas of the bladder. Oncogene 14 (1997) 3059-3066
    • (1997) Oncogene , vol.14 , pp. 3059-3066
    • Cappellen, D.1    Gil Diez de Medina, S.2    Chopin, D.3
  • 114
    • 0032545982 scopus 로고    scopus 로고
    • Cluster of allele losses within a 2.5 cM region of chromosome 10 in high-grade invasive bladder cancer
    • Kagan J., Liu J., Stein J.D., et al. Cluster of allele losses within a 2.5 cM region of chromosome 10 in high-grade invasive bladder cancer. Oncogene 16 (1998) 909-913
    • (1998) Oncogene , vol.16 , pp. 909-913
    • Kagan, J.1    Liu, J.2    Stein, J.D.3
  • 115
    • 0033762188 scopus 로고    scopus 로고
    • Molecular analysis of PTEN and MXI1 in primary bladder carcinoma
    • Wang D.S., Rieger-Christ K., Latini J.M., et al. Molecular analysis of PTEN and MXI1 in primary bladder carcinoma. Int J Cancer 88 (2000) 620-625
    • (2000) Int J Cancer , vol.88 , pp. 620-625
    • Wang, D.S.1    Rieger-Christ, K.2    Latini, J.M.3
  • 116
    • 0033653239 scopus 로고    scopus 로고
    • Inactivation of MMAC1 in bladder transitional-cell carcinoma cell lines and specimens
    • Liu J., Babaian D.C., Liebert M., et al. Inactivation of MMAC1 in bladder transitional-cell carcinoma cell lines and specimens. Mol Carcinog 29 (2000) 143-150
    • (2000) Mol Carcinog , vol.29 , pp. 143-150
    • Liu, J.1    Babaian, D.C.2    Liebert, M.3
  • 117
    • 0035949707 scopus 로고    scopus 로고
    • Haploinsufficiency of the PTEN tumor suppressor gene promotes prostate cancer progression
    • Kwabi-Addo B., Giri D., Schmidt K., et al. Haploinsufficiency of the PTEN tumor suppressor gene promotes prostate cancer progression. Proc Natl Acad Sci U S A 98 (2001) 11563-11568
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 11563-11568
    • Kwabi-Addo, B.1    Giri, D.2    Schmidt, K.3
  • 118
    • 44849089702 scopus 로고    scopus 로고
    • PTEN haploinsufficiency accelerates formation of high-grade astrocytomas
    • Kwon C.H., Zhao D., Chen J., et al. PTEN haploinsufficiency accelerates formation of high-grade astrocytomas. Cancer Res 68 (2008) 3286-3294
    • (2008) Cancer Res , vol.68 , pp. 3286-3294
    • Kwon, C.H.1    Zhao, D.2    Chen, J.3
  • 119
    • 4644285846 scopus 로고    scopus 로고
    • PTEN can inhibit in vitro organotypic and in vivo orthotopic invasion of human bladder cancer cells even in the absence of its lipid phosphatide activity
    • Gildea J.J., Herlevsen M., Harding M.A., et al. PTEN can inhibit in vitro organotypic and in vivo orthotopic invasion of human bladder cancer cells even in the absence of its lipid phosphatide activity. Oncogene 23 (2004) 6788-6797
    • (2004) Oncogene , vol.23 , pp. 6788-6797
    • Gildea, J.J.1    Herlevsen, M.2    Harding, M.A.3
  • 120
    • 33748999833 scopus 로고    scopus 로고
    • Hyperplasia and carcinomas in PTEN-deficient mice and reduced PTEN protein in human bladder cancer patients
    • Tsuruta H., Kishimoto H., Sasaki T., et al. Hyperplasia and carcinomas in PTEN-deficient mice and reduced PTEN protein in human bladder cancer patients. Cancer Res 66 (2006) 8389-8396
    • (2006) Cancer Res , vol.66 , pp. 8389-8396
    • Tsuruta, H.1    Kishimoto, H.2    Sasaki, T.3
  • 121
    • 0025832477 scopus 로고
    • Amplification and over-expression of c-erbB-2 in transitional cell carcinoma of the urinary bladder
    • Coombs L.M., Pigott D.A., Sweeney E., et al. Amplification and over-expression of c-erbB-2 in transitional cell carcinoma of the urinary bladder. Br J Cancer 63 (1991) 601-608
    • (1991) Br J Cancer , vol.63 , pp. 601-608
    • Coombs, L.M.1    Pigott, D.A.2    Sweeney, E.3
  • 122
    • 0028883362 scopus 로고
    • Prognostic value of amplification of c-erb-B2 in bladder carcinoma
    • Lonn U., Lonn S., Friberg S., et al. Prognostic value of amplification of c-erb-B2 in bladder carcinoma. Clin Cancer Res 1 (1995) 1189-1194
    • (1995) Clin Cancer Res , vol.1 , pp. 1189-1194
    • Lonn, U.1    Lonn, S.2    Friberg, S.3
  • 123
    • 0034185043 scopus 로고    scopus 로고
    • C-ERBB-2 gene amplification as a prognostic marker in human bladder cancer
    • Miyamoto H., Kubota Y., Noguchi S., et al. C-ERBB-2 gene amplification as a prognostic marker in human bladder cancer. Urology 55 (2000) 679-683
    • (2000) Urology , vol.55 , pp. 679-683
    • Miyamoto, H.1    Kubota, Y.2    Noguchi, S.3
  • 124
    • 0027215064 scopus 로고
    • Heterogeneity of erbB-2 gene amplification in bladder cancer
    • Sauter G., Moch H., Moore D., et al. Heterogeneity of erbB-2 gene amplification in bladder cancer. Cancer Res 53 (1993) 2199-2203
    • (1993) Cancer Res , vol.53 , pp. 2199-2203
    • Sauter, G.1    Moch, H.2    Moore, D.3
  • 125
    • 10744229554 scopus 로고    scopus 로고
    • HER-2 and TOP2A coamplification in urinary bladder cancer
    • Simon R., Atefy R., Wagner U., et al. HER-2 and TOP2A coamplification in urinary bladder cancer. Int J Cancer 107 (2003) 764-772
    • (2003) Int J Cancer , vol.107 , pp. 764-772
    • Simon, R.1    Atefy, R.2    Wagner, U.3
  • 126
    • 0032529439 scopus 로고    scopus 로고
    • Genetic alterations in primary bladder cancers and their metastases
    • Hovey R.M., Chu L., Balazs M., et al. Genetic alterations in primary bladder cancers and their metastases. Cancer Res 58 (1998) 3555-3560
    • (1998) Cancer Res , vol.58 , pp. 3555-3560
    • Hovey, R.M.1    Chu, L.2    Balazs, M.3
  • 127
    • 0034321971 scopus 로고    scopus 로고
    • Patterns of chromosomal imbalances in muscle invasive bladder cancer
    • Simon R., Burger H., Semjonow A., et al. Patterns of chromosomal imbalances in muscle invasive bladder cancer. Int J Oncol 17 (2000) 1025-1029
    • (2000) Int J Oncol , vol.17 , pp. 1025-1029
    • Simon, R.1    Burger, H.2    Semjonow, A.3
  • 128
    • 0037905690 scopus 로고    scopus 로고
    • Array-based comparative genomic hybridization for genome-wide screening of DNA copy number in bladder tumors
    • Veltman J.A., Fridlyand J., Pejavar S., et al. Array-based comparative genomic hybridization for genome-wide screening of DNA copy number in bladder tumors. Cancer Res 63 (2003) 2872-2880
    • (2003) Cancer Res , vol.63 , pp. 2872-2880
    • Veltman, J.A.1    Fridlyand, J.2    Pejavar, S.3
  • 129
    • 0035135725 scopus 로고    scopus 로고
    • Cytogenetic analysis of multifocal bladder cancer supports a monoclonal origin and intraepithelial spread of tumor cells
    • Simon R., Eltze E., Schafer K.L., et al. Cytogenetic analysis of multifocal bladder cancer supports a monoclonal origin and intraepithelial spread of tumor cells. Cancer Res 61 (2001) 355-362
    • (2001) Cancer Res , vol.61 , pp. 355-362
    • Simon, R.1    Eltze, E.2    Schafer, K.L.3
  • 130
    • 20344375744 scopus 로고    scopus 로고
    • Bladder cancer outcome and subtype classification by gene expression
    • Blaveri E., Simko J.P., Korkola J.E., et al. Bladder cancer outcome and subtype classification by gene expression. Clin Cancer Res 11 (2005) 4044-4055
    • (2005) Clin Cancer Res , vol.11 , pp. 4044-4055
    • Blaveri, E.1    Simko, J.P.2    Korkola, J.E.3
  • 131
    • 0035259439 scopus 로고    scopus 로고
    • Tree models for dependent copy number changes in bladder cancer
    • Schaffer A.A., Simon R., Desper R., et al. Tree models for dependent copy number changes in bladder cancer. Int J Oncol 18 (2001) 349-354
    • (2001) Int J Oncol , vol.18 , pp. 349-354
    • Schaffer, A.A.1    Simon, R.2    Desper, R.3
  • 132
    • 70449526527 scopus 로고    scopus 로고
    • An updated critical analysis of the treatment strategy for newly diagnosed high-grade T1 (previously T1G3) bladder cancer
    • Kulkarni G.S., Hakenberg O.W., Gschwend J.E., et al. An updated critical analysis of the treatment strategy for newly diagnosed high-grade T1 (previously T1G3) bladder cancer. Eur Urol 57 (2010) 60-70
    • (2010) Eur Urol , vol.57 , pp. 60-70
    • Kulkarni, G.S.1    Hakenberg, O.W.2    Gschwend, J.E.3
  • 133
    • 72149108711 scopus 로고    scopus 로고
    • Characteristics and outcomes of patients with clinical T1 grade 3 urothelial carcinoma treated with radical cystectomy: Results from an international cohort
    • Fritsche H.M., Burger M., Svatek R.S., et al. Characteristics and outcomes of patients with clinical T1 grade 3 urothelial carcinoma treated with radical cystectomy: Results from an international cohort. Eur Urol 57 (2010) 300-309
    • (2010) Eur Urol , vol.57 , pp. 300-309
    • Fritsche, H.M.1    Burger, M.2    Svatek, R.S.3
  • 134
    • 70350324546 scopus 로고    scopus 로고
    • Incidental diagnosis of transitional cell carcinoma during percutaneous nephrolithotomy
    • Inci K., Guliyev F., Bilen C.Y., et al. Incidental diagnosis of transitional cell carcinoma during percutaneous nephrolithotomy. Urol Int 83 (2009) 291-294
    • (2009) Urol Int , vol.83 , pp. 291-294
    • Inci, K.1    Guliyev, F.2    Bilen, C.Y.3
  • 135
    • 54049119606 scopus 로고    scopus 로고
    • The optimal management of T1G3 bladder cancer
    • Emiliozzi P., Pansadoro A., and Pansadoro V. The optimal management of T1G3 bladder cancer. BJU Int 102 (2008) 1265-1273
    • (2008) BJU Int , vol.102 , pp. 1265-1273
    • Emiliozzi, P.1    Pansadoro, A.2    Pansadoro, V.3
  • 136
    • 34447105866 scopus 로고    scopus 로고
    • Difficult decisions in urologic oncology: Management of high-grade T1 transitional cell carcinoma of the bladder
    • Soloway M.S., Lee C.T., Steinberg G.D., et al. Difficult decisions in urologic oncology: Management of high-grade T1 transitional cell carcinoma of the bladder. Urol Oncol 25 (2007) 338-340
    • (2007) Urol Oncol , vol.25 , pp. 338-340
    • Soloway, M.S.1    Lee, C.T.2    Steinberg, G.D.3
  • 137
    • 33748125900 scopus 로고    scopus 로고
    • Controversial issues and optimal management of stage T1G3 bladder cancer
    • Metwalli A.R., and Kamat A.M. Controversial issues and optimal management of stage T1G3 bladder cancer. Expert Rev Anticancer Ther 6 (2006) 1283-1294
    • (2006) Expert Rev Anticancer Ther , vol.6 , pp. 1283-1294
    • Metwalli, A.R.1    Kamat, A.M.2
  • 138
    • 65349141879 scopus 로고    scopus 로고
    • Management of the first recurrence of T1G3 bladder cancer: Does intravesical chemotherapy deserve a chance?
    • Witjes J.A. Management of the first recurrence of T1G3 bladder cancer: Does intravesical chemotherapy deserve a chance?. Urol Oncol 27 (2009) 322-324
    • (2009) Urol Oncol , vol.27 , pp. 322-324
    • Witjes, J.A.1
  • 139
    • 77953815698 scopus 로고    scopus 로고
    • Intravesical mitomycin c combined with hyperthermia for patients with T1G3 transitional cell carcinoma of the bladder
    • Epub ahead of print
    • Halachmi S., Moskovitz B., Maffezzini M., et al. Intravesical mitomycin c combined with hyperthermia for patients with T1G3 transitional cell carcinoma of the bladder. Urol Oncol (2009) 322-324 Epub ahead of print
    • (2009) Urol Oncol , pp. 322-324
    • Halachmi, S.1    Moskovitz, B.2    Maffezzini, M.3
  • 140
    • 72249085781 scopus 로고    scopus 로고
    • Cost-effectiveness analysis of immediate radical cystectomy versus intravesical bacillus Calmette-Guerin therapy for high-risk, high-grade (T1G3) bladder cancer
    • Kulkarni G.S., Alibhai S.M., Finelli A., et al. Cost-effectiveness analysis of immediate radical cystectomy versus intravesical bacillus Calmette-Guerin therapy for high-risk, high-grade (T1G3) bladder cancer. Cancer 115 (2009) 5450-5459
    • (2009) Cancer , vol.115 , pp. 5450-5459
    • Kulkarni, G.S.1    Alibhai, S.M.2    Finelli, A.3
  • 141
    • 72249117973 scopus 로고    scopus 로고
    • High-risk, high-grade (T1G3) bladder cancer: Models versus reality
    • Herr H.W. High-risk, high-grade (T1G3) bladder cancer: Models versus reality. Cancer 115 (2009) 5366-5367
    • (2009) Cancer , vol.115 , pp. 5366-5367
    • Herr, H.W.1
  • 142
    • 63649106449 scopus 로고    scopus 로고
    • Prognostic significance of nonpapillary tumor morphology as a predictor of cancer progression and survival in patients with primary T1G3 bladder cancer
    • Park J., Song C., Hong J.H., et al. Prognostic significance of nonpapillary tumor morphology as a predictor of cancer progression and survival in patients with primary T1G3 bladder cancer. World J Urol 27 (2009) 277-283
    • (2009) World J Urol , vol.27 , pp. 277-283
    • Park, J.1    Song, C.2    Hong, J.H.3
  • 143
    • 36448952298 scopus 로고    scopus 로고
    • Organ preservation for T1G3 bladder cancer: Is it feasible?
    • Thalmann G. Organ preservation for T1G3 bladder cancer: Is it feasible?. Eur Urol 53 (2008) 27-29
    • (2008) Eur Urol , vol.53 , pp. 27-29
    • Thalmann, G.1
  • 144
    • 34548427442 scopus 로고    scopus 로고
    • Prognostic value of p53, Ki-67, microstaging and microvessel density in pT1G3 bladder tumors: Creation of risk groups for progression
    • Queipo-Zaragoza J.A., Ruiz-Cerda J.L., Vera-Donoso C.D., et al. Prognostic value of p53, Ki-67, microstaging and microvessel density in pT1G3 bladder tumors: Creation of risk groups for progression. Scand J Urol Nephrol 41 (2007) 283-289
    • (2007) Scand J Urol Nephrol , vol.41 , pp. 283-289
    • Queipo-Zaragoza, J.A.1    Ruiz-Cerda, J.L.2    Vera-Donoso, C.D.3
  • 145
    • 77953841212 scopus 로고    scopus 로고
    • Serretta V, Morgia G, Altieri V, et al.; members of Gruppo Studi Tumori Urologici (GSTU) Foundation (2010). A 1-year maintenance after early adjuvant intravesical chemotherapy has a limited efficacy in preventing recurrence of intermediate risk non-muscle-invasive bladder cancer. BJU Int (in press).
    • Serretta V, Morgia G, Altieri V, et al.; members of Gruppo Studi Tumori Urologici (GSTU) Foundation (2010). A 1-year maintenance after early adjuvant intravesical chemotherapy has a limited efficacy in preventing recurrence of intermediate risk non-muscle-invasive bladder cancer. BJU Int (in press).
  • 146
    • 70350565997 scopus 로고    scopus 로고
    • Clinical Outcome in a Contemporary Series of Restaged Patients with Clinical T1 Bladder Cancer
    • Dalbagni G., Vora K., Kaag M., et al. Clinical Outcome in a Contemporary Series of Restaged Patients with Clinical T1 Bladder Cancer. Eur Urol 56 (2009) 903-910
    • (2009) Eur Urol , vol.56 , pp. 903-910
    • Dalbagni, G.1    Vora, K.2    Kaag, M.3
  • 147
    • 0033571112 scopus 로고    scopus 로고
    • Chromosomal imbalances are associated with a high risk of progression in early invasive (pT1) urinary bladder cancer
    • Richter J., Wagner U., Schraml P., et al. Chromosomal imbalances are associated with a high risk of progression in early invasive (pT1) urinary bladder cancer. Cancer Res 59 (1999) 5687-5691
    • (1999) Cancer Res , vol.59 , pp. 5687-5691
    • Richter, J.1    Wagner, U.2    Schraml, P.3
  • 148
    • 0034642304 scopus 로고    scopus 로고
    • Molecular evolution of multiple recurrent cancers of the bladder
    • van Tilborg A.A., de Vries A., de Bont M., et al. Molecular evolution of multiple recurrent cancers of the bladder. Hum Mol Genet 9 (2000) 2973-2980
    • (2000) Hum Mol Genet , vol.9 , pp. 2973-2980
    • van Tilborg, A.A.1    de Vries, A.2    de Bont, M.3
  • 149
    • 1542405934 scopus 로고    scopus 로고
    • FGFR3 and P53 characterize alternative genetic pathways in the pathogenesis of urothelial cell carcinoma
    • van Rhijn B.W., van der Kwast T.H., Vis A.N., et al. FGFR3 and P53 characterize alternative genetic pathways in the pathogenesis of urothelial cell carcinoma. Cancer Res 64 (2004) 1911-1914
    • (2004) Cancer Res , vol.64 , pp. 1911-1914
    • van Rhijn, B.W.1    van der Kwast, T.H.2    Vis, A.N.3
  • 150
    • 0030875221 scopus 로고    scopus 로고
    • Marked genetic differences between stage pTa and stage pT1 papillary bladder cancer detected by comparative genomic hybridization
    • Richter J., Jiang F., Gorog J.P., et al. Marked genetic differences between stage pTa and stage pT1 papillary bladder cancer detected by comparative genomic hybridization. Cancer Res 57 (1997) 2860-2864
    • (1997) Cancer Res , vol.57 , pp. 2860-2864
    • Richter, J.1    Jiang, F.2    Gorog, J.P.3
  • 151
    • 0027185472 scopus 로고
    • Characterization of chromosome 9 deletions in transitional cell carcinoma by microsatellite assay
    • Linnenbach A.J., Pressler L.B., Seng B.A., et al. Characterization of chromosome 9 deletions in transitional cell carcinoma by microsatellite assay. Hum Mol Genet 2 (1993) 1407-1411
    • (1993) Hum Mol Genet , vol.2 , pp. 1407-1411
    • Linnenbach, A.J.1    Pressler, L.B.2    Seng, B.A.3
  • 152
    • 0025017058 scopus 로고
    • Allelic losses of chromosomes 9, 11, and 17 in human bladder cancer
    • Tsai Y.C., Nichols P.W., Hiti A.L., et al. Allelic losses of chromosomes 9, 11, and 17 in human bladder cancer. Cancer Res 50 (1990) 44-47
    • (1990) Cancer Res , vol.50 , pp. 44-47
    • Tsai, Y.C.1    Nichols, P.W.2    Hiti, A.L.3
  • 153
    • 0033800547 scopus 로고    scopus 로고
    • Karyotypic characterization of urinary bladder transitional cell carcinomas
    • Fadl-Elmula I., Gorunova L., Mandahl N., et al. Karyotypic characterization of urinary bladder transitional cell carcinomas. Genes Chromosomes Cancer 29 (2000) 256-265
    • (2000) Genes Chromosomes Cancer , vol.29 , pp. 256-265
    • Fadl-Elmula, I.1    Gorunova, L.2    Mandahl, N.3
  • 154
    • 0021344956 scopus 로고
    • Nonrandom chromosomal changes in transitional cell carcinoma of the bladder
    • Gibas Z., Prout Jr. G.R., Connolly J.G., et al. Nonrandom chromosomal changes in transitional cell carcinoma of the bladder. Cancer Res 44 (1984) 1257-1264
    • (1984) Cancer Res , vol.44 , pp. 1257-1264
    • Gibas, Z.1    Prout Jr., G.R.2    Connolly, J.G.3
  • 155
    • 0028033422 scopus 로고
    • Rates of p16 (MTS1) mutations in primary tumors with 9p loss
    • Cairns P., Mao L., Merlo A., et al. Rates of p16 (MTS1) mutations in primary tumors with 9p loss. Science 265 (1994) 415-417
    • (1994) Science , vol.265 , pp. 415-417
    • Cairns, P.1    Mao, L.2    Merlo, A.3
  • 156
    • 0028133292 scopus 로고
    • Homozygous deletion mapping at 9p21 in bladder carcinoma defines a critical region within 2cM of IFN-A
    • Devlin J., Keen A.J., and Knowles M.A. Homozygous deletion mapping at 9p21 in bladder carcinoma defines a critical region within 2cM of IFN-A. Oncogene 9 (1994) 2757-2760
    • (1994) Oncogene , vol.9 , pp. 2757-2760
    • Devlin, J.1    Keen, A.J.2    Knowles, M.A.3
  • 157
    • 0028853608 scopus 로고
    • Deletion of the p16 and p15 genes in human bladder tumors
    • Orlow I., Lacombe L., Hannon G.J., et al. Deletion of the p16 and p15 genes in human bladder tumors. J Natl Cancer Inst 87 (1995) 1524-1529
    • (1995) J Natl Cancer Inst , vol.87 , pp. 1524-1529
    • Orlow, I.1    Lacombe, L.2    Hannon, G.J.3
  • 158
    • 0029146575 scopus 로고
    • p16 (CDKN2) is a major deletion target at 9p21 in bladder cancer
    • Williamson M.P., Elder P.A., Shaw M.E., et al. p16 (CDKN2) is a major deletion target at 9p21 in bladder cancer. Hum Mol Genet 4 (1995) 1569-1577
    • (1995) Hum Mol Genet , vol.4 , pp. 1569-1577
    • Williamson, M.P.1    Elder, P.A.2    Shaw, M.E.3
  • 159
    • 23844456592 scopus 로고    scopus 로고
    • Comprehensive analysis of CDKN2A status in microdissected urothelial cell carcinoma reveals potential haploinsufficiency, a high frequency of homozygous co-deletion and associations with clinical phenotype
    • Chapman E.J., Harnden P., Chambers P., et al. Comprehensive analysis of CDKN2A status in microdissected urothelial cell carcinoma reveals potential haploinsufficiency, a high frequency of homozygous co-deletion and associations with clinical phenotype. Clin Cancer Res 11 (2005) 5740-5747
    • (2005) Clin Cancer Res , vol.11 , pp. 5740-5747
    • Chapman, E.J.1    Harnden, P.2    Chambers, P.3
  • 160
    • 36148957497 scopus 로고    scopus 로고
    • Loss of P16 expression and chromosome 9p21 LOH in predicting outcome of patients affected by superficial bladder cancer
    • Bartoletti R., Cai T., Nesi G., et al. Loss of P16 expression and chromosome 9p21 LOH in predicting outcome of patients affected by superficial bladder cancer. J Surg Res 143 (2007) 422-427
    • (2007) J Surg Res , vol.143 , pp. 422-427
    • Bartoletti, R.1    Cai, T.2    Nesi, G.3
  • 161
    • 33750345613 scopus 로고    scopus 로고
    • Prognostic significance of homozygous deletions and multiple duplications at the CDKN2A (p16INK4a)/ARF (p14ARF) locus in urinary bladder cancer
    • Berggren de Verdier P.J., Kumar R., Adolfsson J., et al. Prognostic significance of homozygous deletions and multiple duplications at the CDKN2A (p16INK4a)/ARF (p14ARF) locus in urinary bladder cancer. Scand J Urol Nephrol 40 (2006) 363-369
    • (2006) Scand J Urol Nephrol , vol.40 , pp. 363-369
    • Berggren de Verdier, P.J.1    Kumar, R.2    Adolfsson, J.3
  • 162
    • 0037683269 scopus 로고    scopus 로고
    • Alteration of the PATCHED locus in superficial bladder cancer
    • Aboulkassim T.O., LaRue H., Lemieux P., et al. Alteration of the PATCHED locus in superficial bladder cancer. Oncogene 22 (2003) 2967-2971
    • (2003) Oncogene , vol.22 , pp. 2967-2971
    • Aboulkassim, T.O.1    LaRue, H.2    Lemieux, P.3
  • 163
    • 0032480249 scopus 로고    scopus 로고
    • PTCH gene mutations in invasive transitional cell carcinoma of the bladder
    • McGarvey T.W., Maruta Y., Tomaszewski J.E., et al. PTCH gene mutations in invasive transitional cell carcinoma of the bladder. Oncogene 17 (1998) 1167-1172
    • (1998) Oncogene , vol.17 , pp. 1167-1172
    • McGarvey, T.W.1    Maruta, Y.2    Tomaszewski, J.E.3
  • 164
    • 0032520902 scopus 로고    scopus 로고
    • Structure and methylation-based silencing of a gene (DBCCR1) within a candidate bladder cancer tumor suppressor region at 9q32 q33
    • Habuchi T., Luscombe M., Elder P.A., et al. Structure and methylation-based silencing of a gene (DBCCR1) within a candidate bladder cancer tumor suppressor region at 9q32 q33. Genomics 48 (1998) 277-288
    • (1998) Genomics , vol.48 , pp. 277-288
    • Habuchi, T.1    Luscombe, M.2    Elder, P.A.3
  • 165
    • 0033179836 scopus 로고    scopus 로고
    • A sequence-ready 840-kb PAC contig spanning the candidate tumor suppressor locus DBC1 on human chromosome 9q32 q33
    • Nishiyama H., Hornigold N., Davies A., et al. A sequence-ready 840-kb PAC contig spanning the candidate tumor suppressor locus DBC1 on human chromosome 9q32 q33. Genomics 59 (1999) 335-338
    • (1999) Genomics , vol.59 , pp. 335-338
    • Nishiyama, H.1    Hornigold, N.2    Davies, A.3
  • 166
    • 0034907606 scopus 로고    scopus 로고
    • Alterations of the 9p21 and 9q33 chromosomal bands in clinical bladder cancer specimens by fluorescence in situ hybridization
    • Stadler W.M., Steinberg G., Yang X., et al. Alterations of the 9p21 and 9q33 chromosomal bands in clinical bladder cancer specimens by fluorescence in situ hybridization. Clin Cancer Res 7 (2001) 1676-1682
    • (2001) Clin Cancer Res , vol.7 , pp. 1676-1682
    • Stadler, W.M.1    Steinberg, G.2    Yang, X.3
  • 167
    • 0030965342 scopus 로고    scopus 로고
    • A novel candidate tumor suppressor locus at 9q32 33 in bladder cancer: Localization of the candidate region within a single 840kb YAC
    • Habuchi T., Yoshida O., and Knowles M.A. A novel candidate tumor suppressor locus at 9q32 33 in bladder cancer: Localization of the candidate region within a single 840kb YAC. Hum Mol Genet 6 (1997) 913-919
    • (1997) Hum Mol Genet , vol.6 , pp. 913-919
    • Habuchi, T.1    Yoshida, O.2    Knowles, M.A.3
  • 168
    • 0032833459 scopus 로고    scopus 로고
    • Homozygous deletion at the 9q32 33 candidate tumor suppressor locus in primary human bladder cancer
    • Nishiyama H., Takahashi T., Kakehi Y., et al. Homozygous deletion at the 9q32 33 candidate tumor suppressor locus in primary human bladder cancer. Genes Chromosomes Cancer 26 (1999) 171-175
    • (1999) Genes Chromosomes Cancer , vol.26 , pp. 171-175
    • Nishiyama, H.1    Takahashi, T.2    Kakehi, Y.3
  • 169
    • 0034942681 scopus 로고    scopus 로고
    • Definition of a 1-Mb homozygous deletion at 9q32 q33 in a human bladder-cancer cell line
    • Fujiwara H., Emi M., Nagai H., et al. Definition of a 1-Mb homozygous deletion at 9q32 q33 in a human bladder-cancer cell line. J Hum Genet 46 (2001) 372-377
    • (2001) J Hum Genet , vol.46 , pp. 372-377
    • Fujiwara, H.1    Emi, M.2    Nagai, H.3
  • 170
    • 17744394862 scopus 로고    scopus 로고
    • Hypermethylation at 9q32 33 tumor suppressor region is age-related in normal urothelium and an early and frequent alteration in bladder cancer
    • Habuchi T., Takahashi T., Kakinuma H., et al. Hypermethylation at 9q32 33 tumor suppressor region is age-related in normal urothelium and an early and frequent alteration in bladder cancer. Oncogene 20 (2001) 531-537
    • (2001) Oncogene , vol.20 , pp. 531-537
    • Habuchi, T.1    Takahashi, T.2    Kakinuma, H.3
  • 171
    • 0034194330 scopus 로고    scopus 로고
    • Progressive increases in de novo Methylation of CpG islands in bladder cancer
    • Salem C., Liang G., Tsai Y.C., et al. Progressive increases in de novo Methylation of CpG islands in bladder cancer. Cancer Res 60 (2000) 2473-2476
    • (2000) Cancer Res , vol.60 , pp. 2473-2476
    • Salem, C.1    Liang, G.2    Tsai, Y.C.3
  • 172
    • 0035942497 scopus 로고    scopus 로고
    • Negative regulation of G(1)/S transition by the candidate bladder tumor suppressor gene DBCCR1
    • Nishiyama H., Gill J.H., Pitt E., et al. Negative regulation of G(1)/S transition by the candidate bladder tumor suppressor gene DBCCR1. Oncogene 20 (2001) 2956-2964
    • (2001) Oncogene , vol.20 , pp. 2956-2964
    • Nishiyama, H.1    Gill, J.H.2    Pitt, E.3
  • 173
    • 27244439694 scopus 로고    scopus 로고
    • Loss of heterozygosity on chromosome 9q and p53 alterations in human bladder cancer
    • Hirao S., Hirao T., Marsit C.J., et al. Loss of heterozygosity on chromosome 9q and p53 alterations in human bladder cancer. Cancer 104 (2005) 1918-1923
    • (2005) Cancer , vol.104 , pp. 1918-1923
    • Hirao, S.1    Hirao, T.2    Marsit, C.J.3
  • 174
    • 0034649509 scopus 로고    scopus 로고
    • Chromosome 9 deletions and recurrence of superficial bladder cancer: Identification of 4 regions of prognostic interest
    • Simoneau M., LaRue H., Aboulkassim T.O., et al. Chromosome 9 deletions and recurrence of superficial bladder cancer: Identification of 4 regions of prognostic interest. Oncogene 19 (2000) 6317-6323
    • (2000) Oncogene , vol.19 , pp. 6317-6323
    • Simoneau, M.1    LaRue, H.2    Aboulkassim, T.O.3
  • 175
    • 0036208247 scopus 로고    scopus 로고
    • Identification of loci associated with putative recurrence genes in transitional cell carcinoma of the urinary bladder
    • Edwards J., Duncan P., Going J.J., et al. Identification of loci associated with putative recurrence genes in transitional cell carcinoma of the urinary bladder. J Pathol 196 (2002) 380-385
    • (2002) J Pathol , vol.196 , pp. 380-385
    • Edwards, J.1    Duncan, P.2    Going, J.J.3
  • 176
    • 0034642304 scopus 로고    scopus 로고
    • Molecular evolution of multiple recurrent cancers of the bladder
    • van Tilborg A.A., de Vries A., de Bont M., et al. Molecular evolution of multiple recurrent cancers of the bladder. Hum Mol Genet 9 (2000) 2973-2980
    • (2000) Hum Mol Genet , vol.9 , pp. 2973-2980
    • van Tilborg, A.A.1    de Vries, A.2    de Bont, M.3
  • 177
    • 0033935795 scopus 로고    scopus 로고
    • Initiation development modeling of allelic losses on chromosome 9 in multifocal bladder cancer
    • Louhelainen J., Wijkstrom H., and Hemminki K. Initiation development modeling of allelic losses on chromosome 9 in multifocal bladder cancer. Eur J Cancer 36 (2000) 1441-1451
    • (2000) Eur J Cancer , vol.36 , pp. 1441-1451
    • Louhelainen, J.1    Wijkstrom, H.2    Hemminki, K.3
  • 178
    • 0036840747 scopus 로고    scopus 로고
    • The random development of LOH on chromosome 9q in superficial bladder cancers
    • van Tilborg A.A., de Vries A., de Bont M., et al. The random development of LOH on chromosome 9q in superficial bladder cancers. J Pathol 198 (2002) 352-358
    • (2002) J Pathol , vol.198 , pp. 352-358
    • van Tilborg, A.A.1    de Vries, A.2    de Bont, M.3
  • 179
    • 0028337512 scopus 로고
    • Definition of 2 regions of deletion on chromosome 9 in carcinoma of the bladder
    • Keen A.J., and Knowles M.A. Definition of 2 regions of deletion on chromosome 9 in carcinoma of the bladder. Oncogene 9 (1994) 2083-2088
    • (1994) Oncogene , vol.9 , pp. 2083-2088
    • Keen, A.J.1    Knowles, M.A.2
  • 180
    • 0027362421 scopus 로고
    • Evidence for 2 bladder cancer suppressor loci on human chromosome 9
    • Ruppert J.M., Tokino K., and Sidransky D. Evidence for 2 bladder cancer suppressor loci on human chromosome 9. Cancer Res 53 (1993) 5093-5095
    • (1993) Cancer Res , vol.53 , pp. 5093-5095
    • Ruppert, J.M.1    Tokino, K.2    Sidransky, D.3
  • 181
    • 2542418023 scopus 로고    scopus 로고
    • Identifying superficial, muscle invasive, and metastasizing transitional cell carcinoma of the bladder: Use of cDNA array analysis of gene expression profiles
    • Modlich O., Prisack H.B., Pitschke G., et al. Identifying superficial, muscle invasive, and metastasizing transitional cell carcinoma of the bladder: Use of cDNA array analysis of gene expression profiles. Clin Cancer Res 10 (2004) 3410-3421
    • (2004) Clin Cancer Res , vol.10 , pp. 3410-3421
    • Modlich, O.1    Prisack, H.B.2    Pitschke, G.3
  • 182
    • 33644867290 scopus 로고    scopus 로고
    • Defining molecular profiles of poor outcome in patients with invasive bladder cancer using oligonucleotide microarrays
    • Sanchez-Carbayo M., Socci N.D., Lozano J., et al. Defining molecular profiles of poor outcome in patients with invasive bladder cancer using oligonucleotide microarrays. J Clin Oncol 24 (2006) 778-789
    • (2006) J Clin Oncol , vol.24 , pp. 778-789
    • Sanchez-Carbayo, M.1    Socci, N.D.2    Lozano, J.3
  • 183
    • 11244298063 scopus 로고    scopus 로고
    • High-density single nucleotide polymorphism array defines novel stage and location dependent allelic imbalances in human bladder tumors
    • Koed K., Wiuf C., Christensen L.L., et al. High-density single nucleotide polymorphism array defines novel stage and location dependent allelic imbalances in human bladder tumors. Cancer Res 65 (2005) 34-45
    • (2005) Cancer Res , vol.65 , pp. 34-45
    • Koed, K.1    Wiuf, C.2    Christensen, L.L.3
  • 184
    • 0037699066 scopus 로고    scopus 로고
    • Genome-wide genetic characterization of bladder cancer: A comparison of high-density single-nucleotide polymorphism arrays and PCR-based microsatellite analysis
    • Hoque M.O., Lee C.C., Cairns P., et al. Genome-wide genetic characterization of bladder cancer: A comparison of high-density single-nucleotide polymorphism arrays and PCR-based microsatellite analysis. Cancer Res 63 (2003) 2216-2222
    • (2003) Cancer Res , vol.63 , pp. 2216-2222
    • Hoque, M.O.1    Lee, C.C.2    Cairns, P.3
  • 185
    • 69249131339 scopus 로고    scopus 로고
    • Outcomes and response to therapy in bladder cancer - are biomarkers of any help?
    • Goebell P.J. Outcomes and response to therapy in bladder cancer - are biomarkers of any help?. Minerva Urol Nefrol 61 (2009) 91-107
    • (2009) Minerva Urol Nefrol , vol.61 , pp. 91-107
    • Goebell, P.J.1
  • 186
    • 0032535274 scopus 로고    scopus 로고
    • Clonal and chronological genetic analysis of multifocal cancers of the bladder and upper urinary tract
    • Takahashi T., Habuchi T., Kakehi Y., et al. Clonal and chronological genetic analysis of multifocal cancers of the bladder and upper urinary tract. Cancer Res 58 (1998) 5835-5841
    • (1998) Cancer Res , vol.58 , pp. 5835-5841
    • Takahashi, T.1    Habuchi, T.2    Kakehi, Y.3
  • 187
    • 0035890358 scopus 로고    scopus 로고
    • Identification of cytogenetic subgroups and karyotypic pathways in transitional cell carcinoma
    • Hoglund M., Sall T., Heim S., et al. Identification of cytogenetic subgroups and karyotypic pathways in transitional cell carcinoma. Cancer Res 61 (2001) 8241-8246
    • (2001) Cancer Res , vol.61 , pp. 8241-8246
    • Hoglund, M.1    Sall, T.2    Heim, S.3
  • 188
    • 2942533928 scopus 로고    scopus 로고
    • Pathways of urothelial cancer progression suggested by Bayesian network analysis of allelotyping data
    • Bulashevska S., Szakacs O., Brors B., et al. Pathways of urothelial cancer progression suggested by Bayesian network analysis of allelotyping data. Int J Cancer 110 (2004) 850-856
    • (2004) Int J Cancer , vol.110 , pp. 850-856
    • Bulashevska, S.1    Szakacs, O.2    Brors, B.3
  • 189
    • 13944250290 scopus 로고    scopus 로고
    • Statistical behavior of complex cancer karyotypes
    • Hoglund M., Frigyesi A., Sall T., et al. Statistical behavior of complex cancer karyotypes. Genes Chromosomes Cancer 42 (2005) 327-341
    • (2005) Genes Chromosomes Cancer , vol.42 , pp. 327-341
    • Hoglund, M.1    Frigyesi, A.2    Sall, T.3
  • 190
    • 33751569082 scopus 로고    scopus 로고
    • Natural history of urothelial inverted papilloma
    • Sung M.T., Maclennan G.T., Lopez-Beltran A., et al. Natural history of urothelial inverted papilloma. Cancer 107 (2006) 2622-2627
    • (2006) Cancer , vol.107 , pp. 2622-2627
    • Sung, M.T.1    Maclennan, G.T.2    Lopez-Beltran, A.3
  • 191
    • 33748872729 scopus 로고    scopus 로고
    • Inverted papilloma of the urinary bladder: A molecular genetic appraisal
    • Sung M.T., Eble J.N., Wang M., et al. Inverted papilloma of the urinary bladder: A molecular genetic appraisal. Mod Pathol 19 (2006) 1289-1294
    • (2006) Mod Pathol , vol.19 , pp. 1289-1294
    • Sung, M.T.1    Eble, J.N.2    Wang, M.3
  • 192
    • 34447301827 scopus 로고    scopus 로고
    • Low frequency of molecular changes and tumor recurrence in inverted papillomas of the urinary tract
    • Eiber M., van Oers J.M., Zwarthoff E.C., et al. Low frequency of molecular changes and tumor recurrence in inverted papillomas of the urinary tract. Am J Surg Pathol 31 (2007) 938-946
    • (2007) Am J Surg Pathol , vol.31 , pp. 938-946
    • Eiber, M.1    van Oers, J.M.2    Zwarthoff, E.C.3
  • 193
    • 0033030354 scopus 로고    scopus 로고
    • Frequent genetic alterations in simple urothelial hyperplasias of the bladder in patients with papillary urothelial carcinoma
    • Hartmann A., Moser K., Kriegmair M., et al. Frequent genetic alterations in simple urothelial hyperplasias of the bladder in patients with papillary urothelial carcinoma. Am J Pathol 154 (1999) 721-727
    • (1999) Am J Pathol , vol.154 , pp. 721-727
    • Hartmann, A.1    Moser, K.2    Kriegmair, M.3
  • 194
    • 0037222796 scopus 로고    scopus 로고
    • Frequent genetic alterations in flat urothelial hyperplasias and concomitant papillary bladder cancer as detected by CGH, LOH, and FISH analyses
    • Obermann E.C., Junker K., Stoehr R., et al. Frequent genetic alterations in flat urothelial hyperplasias and concomitant papillary bladder cancer as detected by CGH, LOH, and FISH analyses. J Pathol 199 (2003) 50-57
    • (2003) J Pathol , vol.199 , pp. 50-57
    • Obermann, E.C.1    Junker, K.2    Stoehr, R.3
  • 195
    • 33746376029 scopus 로고    scopus 로고
    • Chromosome 9 deletions are more frequent than FGFR3 mutations in flat urothelial hyperplasias of the bladder
    • van Oers J.M., Adam C., and Denzinger S. Chromosome 9 deletions are more frequent than FGFR3 mutations in flat urothelial hyperplasias of the bladder. Int J Cancer 119 (2006) 1212-1215
    • (2006) Int J Cancer , vol.119 , pp. 1212-1215
    • van Oers, J.M.1    Adam, C.2    Denzinger, S.3
  • 196
    • 0033896830 scopus 로고    scopus 로고
    • Genetic and epigenetic alterations in normal bladder epithelium in patients with metachronous bladder cancer
    • Muto S., Horie S., Takahashi S., et al. Genetic and epigenetic alterations in normal bladder epithelium in patients with metachronous bladder cancer. Cancer Res 60 (2000) 4021-4025
    • (2000) Cancer Res , vol.60 , pp. 4021-4025
    • Muto, S.1    Horie, S.2    Takahashi, S.3
  • 197
    • 67649810755 scopus 로고    scopus 로고
    • Prediction models for transitional cell carcinoma
    • Kattan M.W. Prediction models for transitional cell carcinoma. J Urol 182 (2009) 423-424
    • (2009) J Urol , vol.182 , pp. 423-424
    • Kattan, M.W.1
  • 198
    • 77249163101 scopus 로고    scopus 로고
    • Prediction models in urology: Are they any good, and how would we know anyway?
    • Vickers A. Prediction models in urology: Are they any good, and how would we know anyway?. Eur Urol 57 (2010) 571-573
    • (2010) Eur Urol , vol.57 , pp. 571-573
    • Vickers, A.1
  • 199
    • 76249132458 scopus 로고    scopus 로고
    • Ten steps towards improving prognosis research
    • Hemingway H., Riley R.D., and Altman D.G. Ten steps towards improving prognosis research. BMJ 339 (2009) b4184
    • (2009) BMJ , vol.339
    • Hemingway, H.1    Riley, R.D.2    Altman, D.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.