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Volumn 41, Issue 2, 2009, Pages 221-227

Sequence variants at the TERT-CLPTM1L locus associate with many cancer types

(85)  Rafnar, Thorunn a   Sulem, Patrick a   Stacey, Simon N a   Geller, Frank a   Gudmundsson, Julius a   Sigurdsson, Asgeir a   Jakobsdottir, Margret a   Helgadottir, Hafdis a   Thorlacius, Steinunn a   Aben, Katja K H b,c   Blöndal, Thorarinn a   Thorgeirsson, Thorgeir E a   Thorleifsson, Gudmar a   Kristjansson, Kristleifur a   Thorisdottir, Kristin d   Ragnarsson, Rafn e   Sigurgeirsson, Bardur d   Skuladottir, Halla e   Gudbjartsson, Tomas d,e   Isaksson, Helgi J e   more..


Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN RESISTANCE RELATED PROTEIN; PROTEIN; TELOMERASE REVERSE TRANSCRIPTASE; UNCLASSIFIED DRUG;

EID: 59149091340     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.296     Document Type: Article
Times cited : (539)

References (30)
  • 1
    • 55049127580 scopus 로고    scopus 로고
    • Common variants on 1p36 and 1q42 are associated with cutaneous basal cell carcinoma but not with melanoma or pigmentation traits
    • Stacey, S.N. et al. Common variants on 1p36 and 1q42 are associated with cutaneous basal cell carcinoma but not with melanoma or pigmentation traits. Nat. Genet. 40, 1313-1318 (2008).
    • (2008) Nat. Genet , vol.40 , pp. 1313-1318
    • Stacey, S.N.1
  • 2
    • 34247563453 scopus 로고    scopus 로고
    • Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24
    • Gudmundsson, J. et al. Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24. Nat. Genet. 39, 631-637 (2007).
    • (2007) Nat. Genet , vol.39 , pp. 631-637
    • Gudmundsson, J.1
  • 3
    • 34250002140 scopus 로고    scopus 로고
    • Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor-positive breast cancer
    • Stacey, S.N. et al. Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor-positive breast cancer. Nat. Genet. 39, 865-869 (2007).
    • (2007) Nat. Genet , vol.39 , pp. 865-869
    • Stacey, S.N.1
  • 4
    • 34247548755 scopus 로고    scopus 로고
    • Genome-wide association study of prostate cancer identifies a second risk locus at 8q24
    • Yeager, M. et al. Genome-wide association study of prostate cancer identifies a second risk locus at 8q24. Nat. Genet. 39, 645-649 (2007).
    • (2007) Nat. Genet , vol.39 , pp. 645-649
    • Yeager, M.1
  • 5
    • 34247482327 scopus 로고    scopus 로고
    • Multiple regions within 8q24 independently affect risk for prostate cancer
    • Haiman, C.A. et al. Multiple regions within 8q24 independently affect risk for prostate cancer. Nat. Genet. 39, 638-644 (2007).
    • (2007) Nat. Genet , vol.39 , pp. 638-644
    • Haiman, C.A.1
  • 6
    • 34250006413 scopus 로고    scopus 로고
    • Genome-wide association study identifies novel breast cancer susceptibility loci
    • Easton, D.F. et al. Genome-wide association study identifies novel breast cancer susceptibility loci. Nature 447, 1087-1093 (2007).
    • (2007) Nature , vol.447 , pp. 1087-1093
    • Easton, D.F.1
  • 7
    • 34547498546 scopus 로고    scopus 로고
    • A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21
    • Tomlinson, I. et al. A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21. Nat. Genet. 39, 984-988 (2007).
    • (2007) Nat. Genet , vol.39 , pp. 984-988
    • Tomlinson, I.1
  • 8
    • 45549097424 scopus 로고    scopus 로고
    • ASIP and TYR pigmentation variants associate with cutaneous melanoma and basal cell carcinoma
    • Gudbjartsson, D.F. et al. ASIP and TYR pigmentation variants associate with cutaneous melanoma and basal cell carcinoma. Nat. Genet. 40, 886-891 (2008).
    • (2008) Nat. Genet , vol.40 , pp. 886-891
    • Gudbjartsson, D.F.1
  • 9
    • 41649103052 scopus 로고    scopus 로고
    • A variant associated with nicotine dependence, lung cancer and peripheral arterial disease
    • Thorgeirsson, T.E. et al. A variant associated with nicotine dependence, lung cancer and peripheral arterial disease. Nature 452, 638-642 (2008).
    • (2008) Nature , vol.452 , pp. 638-642
    • Thorgeirsson, T.E.1
  • 10
    • 39749129053 scopus 로고    scopus 로고
    • Multiple newly identified loci associated with prostate cancer susceptibility
    • Eeles, R.A. et al. Multiple newly identified loci associated with prostate cancer susceptibility. Nat. Genet. 40, 316-321 (2008).
    • (2008) Nat. Genet , vol.40 , pp. 316-321
    • Eeles, R.A.1
  • 11
    • 41649103682 scopus 로고    scopus 로고
    • A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25
    • Hung, R.J. et al. A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25. Nature 452, 633-637 (2008).
    • (2008) Nature , vol.452 , pp. 633-637
    • Hung, R.J.1
  • 12
    • 42649091460 scopus 로고    scopus 로고
    • Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1
    • Amos, C.I. et al. Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1. Nat. Genet. 40, 616-622 (2008).
    • (2008) Nat. Genet , vol.40 , pp. 616-622
    • Amos, C.I.1
  • 13
    • 39749118602 scopus 로고    scopus 로고
    • Multiple loci identified in a genome-wide association study of prostate cancer
    • Thomas, G. et al. Multiple loci identified in a genome-wide association study of prostate cancer. Nat. Genet. 40, 310-315 (2008).
    • (2008) Nat. Genet , vol.40 , pp. 310-315
    • Thomas, G.1
  • 14
    • 55049112064 scopus 로고    scopus 로고
    • Sequence variant on 8q24 confers susceptibility to urinary bladder cancer
    • Kiemeney, L.A. et al. Sequence variant on 8q24 confers susceptibility to urinary bladder cancer. Nat. Genet. 40, 1307-1312 (2008).
    • (2008) Nat. Genet , vol.40 , pp. 1307-1312
    • Kiemeney, L.A.1
  • 15
    • 33745169697 scopus 로고    scopus 로고
    • A common variant associated with prostate cancer in European and African populations
    • Amundadottir, L.T. et al. A common variant associated with prostate cancer in European and African populations. Nat. Genet. 38, 652-658 (2006).
    • (2006) Nat. Genet , vol.38 , pp. 652-658
    • Amundadottir, L.T.1
  • 16
    • 34547121725 scopus 로고    scopus 로고
    • A common genetic risk factor for colorectal and prostate cancer
    • Haiman, C.A. et al. A common genetic risk factor for colorectal and prostate cancer. Nat. Genet. 39, 954-956 (2007).
    • (2007) Nat. Genet , vol.39 , pp. 954-956
    • Haiman, C.A.1
  • 17
    • 42649118126 scopus 로고    scopus 로고
    • Many sequence variants affecting diversity of adult human height
    • Gudbjartsson, D.F. et al. Many sequence variants affecting diversity of adult human height. Nat. Genet. 40, 609-615 (2008).
    • (2008) Nat. Genet , vol.40 , pp. 609-615
    • Gudbjartsson, D.F.1
  • 18
    • 0034805276 scopus 로고    scopus 로고
    • A novel gene, CRR9, which was up-regulated in CDDP-resistant ovarian tumor cell line, was associated with apoptosis
    • Yamamoto, K., Okamoto, A., Isonishi, S., Ochiai, K. & Ohtake, Y. A novel gene, CRR9, which was up-regulated in CDDP-resistant ovarian tumor cell line, was associated with apoptosis. Biochem. Biophys. Res. Commun. 280, 1148-1154 (2001).
    • (2001) Biochem. Biophys. Res. Commun , vol.280 , pp. 1148-1154
    • Yamamoto, K.1    Okamoto, A.2    Isonishi, S.3    Ochiai, K.4    Ohtake, Y.5
  • 19
    • 0035929353 scopus 로고    scopus 로고
    • Switching and signaling at the telomere
    • Blackburn, E.H. Switching and signaling at the telomere. Cell 106, 661-673 (2001).
    • (2001) Cell , vol.106 , pp. 661-673
    • Blackburn, E.H.1
  • 20
    • 0042140590 scopus 로고    scopus 로고
    • Telomere dysfunction: A potential cancer predisposition factor
    • Wu, X. et al. Telomere dysfunction: a potential cancer predisposition factor. J. Natl. Cancer Inst. 95, 1211-1218 (2003).
    • (2003) J. Natl. Cancer Inst , vol.95 , pp. 1211-1218
    • Wu, X.1
  • 21
    • 34347223645 scopus 로고    scopus 로고
    • Short telomere length and breast cancer risk: A study in sister sets
    • Shen, J. et al. Short telomere length and breast cancer risk: a study in sister sets. Cancer Res. 67, 5538-5544 (2007).
    • (2007) Cancer Res , vol.67 , pp. 5538-5544
    • Shen, J.1
  • 22
    • 34249001353 scopus 로고    scopus 로고
    • Short telomeres in aggressive non-Hodgkin's lymphoma as a risk factor in lymphomagenesis
    • Widmann, T.A., Herrmann, M., Taha, N., Konig, J. & Pfreundschuh, M. Short telomeres in aggressive non-Hodgkin's lymphoma as a risk factor in lymphomagenesis. Exp. Hematol. 35, 939-946 (2007).
    • (2007) Exp. Hematol , vol.35 , pp. 939-946
    • Widmann, T.A.1    Herrmann, M.2    Taha, N.3    Konig, J.4    Pfreundschuh, M.5
  • 23
    • 38949140844 scopus 로고    scopus 로고
    • Leukocyte telomere length predicts cancer risk in Barrett's esophagus
    • Risques, R.A. et al. Leukocyte telomere length predicts cancer risk in Barrett's esophagus. Cancer Epidemiol. Biomarkers Prev. 16, 2649-2655 (2007).
    • (2007) Cancer Epidemiol. Biomarkers Prev , vol.16 , pp. 2649-2655
    • Risques, R.A.1
  • 24
    • 58549092034 scopus 로고    scopus 로고
    • Han, J. et al. A prospective study of telomere length and the risk of skin cancer. J. Invest. Dermatol. advance online publication, doi: 10.1038/jid.2008.238 (31 July 2008).
    • Han, J. et al. A prospective study of telomere length and the risk of skin cancer. J. Invest. Dermatol. advance online publication, doi: 10.1038/jid.2008.238 (31 July 2008).
  • 25
    • 0037057508 scopus 로고    scopus 로고
    • Genetic alterations in cervical carcinomas: Frequent low-level amplifications of oncogenes are associated with human papillomavirus infection
    • Zhang, A. et al. Genetic alterations in cervical carcinomas: frequent low-level amplifications of oncogenes are associated with human papillomavirus infection. Int. J. Cancer 101, 427-433 (2002).
    • (2002) Int. J. Cancer , vol.101 , pp. 427-433
    • Zhang, A.1
  • 26
    • 40049087659 scopus 로고    scopus 로고
    • Gain at chromosomal region 5p15.33, containing TERT, is the most frequent genetic event in early stages of non-small cell lung cancer
    • Kang, J.U., Koo, S.H., Kwon, K.C., Park, J.W. & Kim, J.M. Gain at chromosomal region 5p15.33, containing TERT, is the most frequent genetic event in early stages of non-small cell lung cancer. Cancer Genet. Cytogenet. 182, 1-11 (2008).
    • (2008) Cancer Genet. Cytogenet , vol.182 , pp. 1-11
    • Kang, J.U.1    Koo, S.H.2    Kwon, K.C.3    Park, J.W.4    Kim, J.M.5
  • 27
    • 42649136554 scopus 로고    scopus 로고
    • A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3
    • Tomlinson, I.P. et al. A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3. Nat. Genet. 40, 623-630 (2008).
    • (2008) Nat. Genet , vol.40 , pp. 623-630
    • Tomlinson, I.P.1
  • 28
    • 23844517498 scopus 로고    scopus 로고
    • Obesity, cigarette smoking, and telomere length in women
    • Valdes, A.M. et al. Obesity, cigarette smoking, and telomere length in women. Lancet 366, 662-664 (2005).
    • (2005) Lancet , vol.366 , pp. 662-664
    • Valdes, A.M.1
  • 29
    • 13144305133 scopus 로고    scopus 로고
    • The rate of telomere sequence loss in human leukocytes varies with age
    • Frenck, R.W. Jr., Blackburn, E.H. & Shannon, K.M. The rate of telomere sequence loss in human leukocytes varies with age. Proc. Natl. Acad. Sci. USA 95, 5607-5610 (1998).
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 5607-5610
    • Frenck Jr., R.W.1    Blackburn, E.H.2    Shannon, K.M.3
  • 30
    • 0027993344 scopus 로고
    • Genetic determination of telomere size in humans: A twin study of three age groups
    • Slagboom, P.E., Droog, S. & Boomsma, D.I. Genetic determination of telomere size in humans: a twin study of three age groups. Am. J. Hum. Genet. 55, 876-882 (1994).
    • (1994) Am. J. Hum. Genet , vol.55 , pp. 876-882
    • Slagboom, P.E.1    Droog, S.2    Boomsma, D.I.3


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