메뉴 건너뛰기




Volumn , Issue , 2007, Pages 203-230

Biological Implications and Broader-Range Functions for APOBEC-1 and APOBEC-1 Complementation Factor (ACF)

Author keywords

Apobec 1 complementation factor(ACF); Base modification RNA editing; Biochemical and genetic mechanisms

Indexed keywords


EID: 84889390522     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470262269.ch10     Document Type: Chapter
Times cited : (2)

References (105)
  • 1
    • 0033843588 scopus 로고    scopus 로고
    • Changing genetic information through RNA editing
    • Maas, S., and Rich, A. (2000) Changing genetic information through RNA editing. Bioessays 22, 790-802.
    • (2000) Bioessays , vol.22 , pp. 790-802
    • Maas, S.1    Rich, A.2
  • 2
    • 0037449753 scopus 로고    scopus 로고
    • C-to-U RNA editing: Mechanisms leading to genetic diversity
    • Blanc, V., and Davidson, N. O. (2003) C-to-U RNA editing: Mechanisms leading to genetic diversity. J Biol Chem 278, 1395-1398.
    • (2003) J Biol Chem , vol.278 , pp. 1395-1398
    • Blanc, V.1    Davidson, N.O.2
  • 3
    • 0033970066 scopus 로고    scopus 로고
    • Molecular cloning of apobec-1 complementation factor, a novel RNA-binding protein involved in the editing of apolipoprotein B mRNA
    • Mehta, A., Kinter, M. T., Sherman, N. E., and Driscoll, D. M. (2000) Molecular cloning of apobec-1 complementation factor, a novel RNA-binding protein involved in the editing of apolipoprotein B mRNA. Mol Cell Biol 20, 1846-1854.
    • (2000) Mol Cell Biol , vol.20 , pp. 1846-1854
    • Mehta, A.1    Kinter, M.T.2    Sherman, N.E.3    Driscoll, D.M.4
  • 4
    • 0034733528 scopus 로고    scopus 로고
    • Purification and molecular cloning of a novel essential component of the apolipoproteinBmRNAediting enzyme-complex
    • Lellek, H., Kirsten, R., Diehl, I., Apostel, F., Buck, F., and Greeve, J. (2000) Purification and molecular cloning of a novel essential component of the apolipoproteinBmRNAediting enzyme-complex. J Biol Chem 275, 19848-19856.
    • (2000) J Biol Chem , vol.275 , pp. 19848-19856
    • Lellek, H.1    Kirsten, R.2    Diehl, I.3    Apostel, F.4    Buck, F.5    Greeve, J.6
  • 5
    • 0033827087 scopus 로고    scopus 로고
    • APOLIPOPROTEIN B: mRNA editing, lipoprotein assembly, and presecretory degradation
    • Davidson, N. O., and Shelness, G. S. (2000) APOLIPOPROTEIN B: mRNA editing, lipoprotein assembly, and presecretory degradation. Annu Rev Nutr 20, 169-193.
    • (2000) Annu Rev Nutr , vol.20 , pp. 169-193
    • Davidson, N.O.1    Shelness, G.S.2
  • 6
    • 0027172292 scopus 로고
    • ApolipoproteinBmRNA editing in 12 different mammalian species: Hepatic expression is reflected in low concentrations of apoB-containing plasma lipoproteins
    • Greeve, J., Altkemper, I., Dieterich, J. H., Greten, H., andWindler, E. (1993) ApolipoproteinBmRNA editing in 12 different mammalian species: Hepatic expression is reflected in low concentrations of apoB-containing plasma lipoproteins. J Lipid Res 34, 1367-1383.
    • (1993) J Lipid Res , vol.34 , pp. 1367-1383
    • Greeve, J.1    Altkemper, I.2    Dieterich, J.H.3    Greten, H.4    Windler, E.5
  • 8
    • 0028085932 scopus 로고
    • Dimeric structure of ahuman apolipoprotein B mRNA editing protein and cloning and chromosomal localization of its gene
    • Lau, P. P., Zhu, H. J., Baldini, A., Charnsangavej, C., and Chan, L. (1994) Dimeric structure of ahuman apolipoprotein B mRNA editing protein and cloning and chromosomal localization of its gene. Proc Natl Acad Sci USA 91, 8522-8526.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 8522-8526
    • Lau, P.P.1    Zhu, H.J.2    Baldini, A.3    Charnsangavej, C.4    Chan, L.5
  • 9
    • 0025677193 scopus 로고
    • ApolipoproteinBmessengerRNAeditingisdevelopmentally regulated in pig small intestine: nucleotide comparison of apolipoprotein B editing regions in five species
    • Teng, B., Black, D. D.,andDavidson, N. O. (1990) ApolipoproteinBmessengerRNAeditingisdevelopmentally regulated in pig small intestine: nucleotide comparison of apolipoprotein B editing regions in five species. Biochem Biophys Res Commun 173, 74-80.
    • (1990) Biochem Biophys Res Commun , vol.173 , pp. 74-80
    • Teng, B.1    Black, D.D.2    Davidson, N.O.3
  • 10
    • 0025086368 scopus 로고
    • Recent progress in understanding apolipoprotein B
    • Young, S. G. (1990) Recent progress in understanding apolipoprotein B. Circulation 82, 1574-1594.
    • (1990) Circulation , vol.82 , pp. 1574-1594
    • Young, S.G.1
  • 12
    • 0026441405 scopus 로고
    • Three distinct RNA sequence elements are required for efficient apolipoprotein B (apoB) RNA editing in vitro
    • Backus, J. W., and Smith, H. C. (1992) Three distinct RNA sequence elements are required for efficient apolipoprotein B (apoB) RNA editing in vitro. Nucleic Acids Res 20, 6007-6014.
    • (1992) Nucleic Acids Res , vol.20 , pp. 6007-6014
    • Backus, J.W.1    Smith, H.C.2
  • 13
    • 0033520929 scopus 로고    scopus 로고
    • Phylogenetic analysis of the apolipoprotein B mRNA-editing region, Evidence for a secondary structure between the mooring sequence and the 30 efficiency element
    • Hersberger, M., Patarroyo-White, S., Arnold, K. S., and Innerarity, T. L. (1999) Phylogenetic analysis of the apolipoprotein B mRNA-editing region. Evidence for a secondary structure between the mooring sequence and the 30 efficiency element. J Biol Chem 274, 34590-34597.
    • (1999) J Biol Chem , vol.274 , pp. 34590-34597
    • Hersberger, M.1    Patarroyo-White, S.2    Arnold, K.S.3    Innerarity, T.L.4
  • 14
    • 0033610859 scopus 로고    scopus 로고
    • Secondary structure for the apolipoprotein B mRNA editing site, AU-binding proteins interact with a stem loop
    • Richardson, N., Navaratnam, N., and Scott, J. (1998) Secondary structure for the apolipoprotein B mRNA editing site. AU-binding proteins interact with a stem loop. J Biol Chem 274, 31707-31717.
    • (1998) J Biol Chem , vol.274 , pp. 31707-31717
    • Richardson, N.1    Navaratnam, N.2    Scott, J.3
  • 15
    • 0036170283 scopus 로고    scopus 로고
    • The challenge of target sequence specificity in C!U RNA editing
    • Davidson, N. O. (2002) The challenge of target sequence specificity in C!U RNA editing. J Clin Invest 109, 291-294.
    • (2002) J Clin Invest , vol.109 , pp. 291-294
    • Davidson, N.O.1
  • 16
    • 0032540348 scopus 로고    scopus 로고
    • Two efficiency elements flanking the editing site of cytidine 6666 in the apolipoprotein B mRNA support mooring-dependent editing
    • Hersberger, M., and Innerarity, T. L. (1998) Two efficiency elements flanking the editing site of cytidine 6666 in the apolipoprotein B mRNA support mooring-dependent editing. J Biol Chem 273, 9435-9442.
    • (1998) J Biol Chem , vol.273 , pp. 9435-9442
    • Hersberger, M.1    Innerarity, T.L.2
  • 17
    • 0027200620 scopus 로고
    • Molecular cloning ofan apolipoproteinBmessenger RNA editing protein
    • Teng, B., Burant, C. F., andDavidson, N. O. (1993) Molecular cloning ofan apolipoproteinBmessenger RNA editing protein. Science 260, 1816-1819.
    • (1993) Science , vol.260 , pp. 1816-1819
    • Teng, B.1    Burant, C.F.2    Davidson, N.O.3
  • 18
    • 0028105999 scopus 로고
    • Complementation of apolipoprotein B mRNA editing by human liver accompanied by secretion of apolipoprotein B48
    • Giannoni, F., Bonen, D. K., Funahashi, T., Hadjiagapiou, C., Burant, C. F., andDavidson, N. O. (1994) Complementation of apolipoprotein B mRNA editing by human liver accompanied by secretion of apolipoprotein B48. J Biol Chem 269, 5932-5936.
    • (1994) J Biol Chem , vol.269 , pp. 5932-5936
    • Giannoni, F.1    Bonen, D.K.2    Funahashi, T.3    Hadjiagapiou, C.4    Burant, C.F.5    Davidson, N.O.6
  • 20
    • 0032958220 scopus 로고    scopus 로고
    • Mutational analysis of apolipoproteinBmRNAediting enzyme (Apobec-1): Structure-function relationships ofRNAediting and dimerization
    • Teng, B., Ochsner, S., Zhang, Q., Soman, K. V., Lau, P. P., and Chan, L. (1999) Mutational analysis of apolipoproteinBmRNAediting enzyme (Apobec-1): Structure-function relationships ofRNAediting and dimerization. J Lipid Res 40, 623-635.
    • (1999) J Lipid Res , vol.40 , pp. 623-635
    • Teng, B.1    Ochsner, S.2    Zhang, Q.3    Soman, K.V.4    Lau, P.P.5    Chan, L.6
  • 21
    • 0031019881 scopus 로고    scopus 로고
    • Tissue-specific inhibition of apolipoprotein B mRNA editing in the liver by adenovirus-mediated transfer of a dominant negative mutant APOBEC-1 leads to increased lowdensity lipoprotein in mice
    • Oka, K., Kobayashi, K., Sullivan, M., Martinez, J., Teng, B. B., Ishimura-Oka, K., and Chan, L. (1997) Tissue-specific inhibition of apolipoprotein B mRNA editing in the liver by adenovirus-mediated transfer of a dominant negative mutant APOBEC-1 leads to increased lowdensity lipoprotein in mice. J Biol Chem 272, 1456-1460.
    • (1997) J Biol Chem , vol.272 , pp. 1456-1460
    • Oka, K.1    Kobayashi, K.2    Sullivan, M.3    Martinez, J.4    Teng, B.B.5    Ishimura-Oka, K.6    Chan, L.7
  • 23
    • 0026760497 scopus 로고
    • Evolution of intestinal apolipoproteinBmRNAediting, Chicken apolipoprotein B mRNA is not edited, but chicken enterocytes contain in vitro editing enhancement factor(s)
    • Teng, B., andDavidson, N. O. (1992) Evolution of intestinal apolipoproteinBmRNAediting. Chicken apolipoprotein B mRNA is not edited, but chicken enterocytes contain in vitro editing enhancement factor(s). J Biol Chem 267, 21265-21272.
    • (1992) J Biol Chem , vol.267 , pp. 21265-21272
    • Teng, B.1    Davidson, N.O.2
  • 24
    • 0035846449 scopus 로고    scopus 로고
    • Isolation, characterization and developmental regulation of the human apobec-1 complementation factor (ACF) gene
    • Henderson, J. O., Blanc, V., andDavidson, N. O. (2001) Isolation, characterization and developmental regulation of the human apobec-1 complementation factor (ACF) gene. Biochim Biophys Acta 1522, 22-30.
    • (2001) Biochim Biophys Acta , vol.1522 , pp. 22-30
    • Henderson, J.O.1    Blanc, V.2    Davidson, N.O.3
  • 25
    • 23344436132 scopus 로고    scopus 로고
    • Targeted deletion of the murine apobec-1 complementation factor (acf) gene results in embryonic lethality
    • Blanc, V., Henderson, J. O., Newberry, E. P., Kennedy, S., Luo, J., andDavidson, N. O. (2005) Targeted deletion of the murine apobec-1 complementation factor (acf) gene results in embryonic lethality. Mol Cell Biol 25, 7260-7269.
    • (2005) Mol Cell Biol , vol.25 , pp. 7260-7269
    • Blanc, V.1    Henderson, J.O.2    Newberry, E.P.3    Kennedy, S.4    Luo, J.5    Davidson, N.O.6
  • 26
    • 0027450461 scopus 로고
    • Extract-specific heterogeneity in high-order complexes containing apolipoprotein B mRNA editing activity and RNA-binding proteins
    • Harris, S. G., Sabio, I., Mayer, E., Steinberg, M. F., Backus, J. W., Sparks, J. D., Sparks, C. E., and Smith, H. C. (1993) Extract-specific heterogeneity in high-order complexes containing apolipoprotein B mRNA editing activity and RNA-binding proteins. J Biol Chem 268, 7382-7392.
    • (1993) J Biol Chem , vol.268 , pp. 7382-7392
    • Harris, S.G.1    Sabio, I.2    Mayer, E.3    Steinberg, M.F.4    Backus, J.W.5    Sparks, J.D.6    Sparks, C.E.7    Smith, H.C.8
  • 27
    • 0035824516 scopus 로고    scopus 로고
    • Mutagenesis of apobec-1 complementation factor reveals distinct domains that modulate RNA binding, protein-protein interaction with apobec-1, and complementation ofCtoURNA-editing activity
    • Blanc, V., Henderson, J. O., Kennedy, S., and Davidson, N. O. (2001) Mutagenesis of apobec-1 complementation factor reveals distinct domains that modulate RNA binding, protein-protein interaction with apobec-1, and complementation ofCtoURNA-editing activity. J BiolChem 276, 46386-46393.
    • (2001) J BiolChem , vol.276 , pp. 46386-46393
    • Blanc, V.1    Henderson, J.O.2    Kennedy, S.3    Davidson, N.O.4
  • 29
    • 0033800453 scopus 로고    scopus 로고
    • Cooperative assembly of an hnRNP complex induced by a tissue-specific homolog of polypyrimidine tract binding protein
    • Markovtsov, V., Nikolic, J. M., Goldman, J. A., Turck, C. W., Chou, M. Y., and Black, D. L. (2000) Cooperative assembly of an hnRNP complex induced by a tissue-specific homolog of polypyrimidine tract binding protein. Mol Cell Biol 20, 7463-7479.
    • (2000) Mol Cell Biol , vol.20 , pp. 7463-7479
    • Markovtsov, V.1    Nikolic, J.M.2    Goldman, J.A.3    Turck, C.W.4    Chou, M.Y.5    Black, D.L.6
  • 30
    • 0036154096 scopus 로고    scopus 로고
    • Spec-ific interaction of Smn, the spinal muscular atrophy determining gene product, with hnRNP-R and gry-rbp/hnRNP-Q: A role for Smn in RNA processing in motor axons?
    • Rossoll, W., Kroning, A. K., Ohndorf, U. M., Steegborn, C., Jablonka, S., and Sendtner, M. (2002) Spec-ific interaction of Smn, the spinal muscular atrophy determining gene product, with hnRNP-R and gry-rbp/hnRNP-Q: A role for Smn in RNA processing in motor axons? Hum Mol Genet 11, 93-105.
    • (2002) Hum Mol Genet , vol.11 , pp. 93-105
    • Rossoll, W.1    Kroning, A.K.2    Ohndorf, U.M.3    Steegborn, C.4    Jablonka, S.5    Sendtner, M.6
  • 31
    • 0025749693 scopus 로고
    • ApolipoproteinBmRNAediting is an intranuclear event that occurs posttranscriptionally coincident with splicing and polyadenylation
    • Lau, P. P., Xiong, W. J., Zhu, H. J., Chen, S. H., and Chan, L. (1991) ApolipoproteinBmRNAediting is an intranuclear event that occurs posttranscriptionally coincident with splicing and polyadenylation. J Biol Chem 266, 20550-20554.
    • (1991) J Biol Chem , vol.266 , pp. 20550-20554
    • Lau, P.P.1    Xiong, W.J.2    Zhu, H.J.3    Chen, S.H.4    Chan, L.5
  • 32
    • 0035476679 scopus 로고    scopus 로고
    • SMN interacts with a novel family of hnRNP and spliceosomal proteins
    • Mourelatos, Z., Abel, L., Yong, J., Kataoka, N., and Dreyfuss, G. (2001) SMN interacts with a novel family of hnRNP and spliceosomal proteins. Embo J 20, 5443-5452.
    • (2001) Embo J , vol.20 , pp. 5443-5452
    • Mourelatos, Z.1    Abel, L.2    Yong, J.3    Kataoka, N.4    Dreyfuss, G.5
  • 33
    • 0035861728 scopus 로고    scopus 로고
    • Novel role for RNA-binding protein CUGBP2 in mammalian RNA editing, CUGBP2 modulates C to U editing of apolipoprotein B mRNA by interacting with apobec-1 and ACF, the apobec-1 complementation factor
    • Anant, S., Henderson, J. O., Mukhopadhyay, D., Navaratnam, N., Kennedy, S., Min, J., and Davidson, N. O. (2001) Novel role for RNA-binding protein CUGBP2 in mammalian RNA editing. CUGBP2 modulates C to U editing of apolipoprotein B mRNA by interacting with apobec-1 and ACF, the apobec-1 complementation factor. J Biol Chem 276, 47338-47351.
    • (2001) J Biol Chem , vol.276 , pp. 47338-47351
    • Anant, S.1    Henderson, J.O.2    Mukhopadhyay, D.3    Navaratnam, N.4    Kennedy, S.5    Min, J.6    Davidson, N.O.7
  • 35
    • 8544241736 scopus 로고    scopus 로고
    • Retroviral restrictionbyAPOBECproteins
    • Harris, R. S.,andLiddament, M. T. (2004) Retroviral restrictionbyAPOBECproteins. NatRevImmunol 4, 868-877.
    • (2004) NatRevImmunol , vol.4 , pp. 868-877
    • Harris, R.S.1    Liddament, M.T.2
  • 36
    • 0030667958 scopus 로고    scopus 로고
    • Multiple protein domains determine the cell type-specific nuclear distribution of the catalytic subunit required for apolipoprotein B mRNA editing
    • Yang, Y., Yang, Y., and Smith, H. C. (1997) Multiple protein domains determine the cell type-specific nuclear distribution of the catalytic subunit required for apolipoprotein B mRNA editing. Proc Natl Acad Sci USA 94, 13075-13080.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 13075-13080
    • Yang, Y.1    Yang, Y.2    Smith, H.C.3
  • 37
    • 0041524056 scopus 로고    scopus 로고
    • TheapolipoproteinBmRNAediting complex performs a multifunctional cycle and suppresses nonsense-mediated decay
    • Chester, A., Somasekaram, A., Tzimina, M., Jarmuz, A., Gisbourne, J., O'Keefe, R., Scott, J., and Navaratnam, N. (2003) TheapolipoproteinBmRNAediting complex performs a multifunctional cycle and suppresses nonsense-mediated decay. EMBO J 22, 3971-3982.
    • (2003) EMBO J , vol.22 , pp. 3971-3982
    • Chester, A.1    Somasekaram, A.2    Tzimina, M.3    Jarmuz, A.4    Gisbourne, J.5    O'Keefe, R.6    Scott, J.7    Navaratnam, N.8
  • 38
    • 0035879114 scopus 로고    scopus 로고
    • Intracellular trafficking determinants in APOBEC-1, the catalytic subunit for cytidine to uridine editing of apolipoprotein BmRNA
    • Yang, Y., Sowden, M. P., Yang, Y., and Smith, H. C. (2001) Intracellular trafficking determinants in APOBEC-1, the catalytic subunit for cytidine to uridine editing of apolipoprotein BmRNA. Exp Cell Res 267, 153-164.
    • (2001) Exp Cell Res , vol.267 , pp. 153-164
    • Yang, Y.1    Sowden, M.P.2    Yang, Y.3    Smith, H.C.4
  • 39
    • 0029143353 scopus 로고
    • Developmental regulation of the catalytic subunit of the apolipoprotein B mRNA editing enzyme (APOBEC-1) in human small intestine
    • Giannoni, F., Chou, S. C., Skarosi, S. F., Verp, M. S., Field, F. J., Coleman, R. A., and Davidson, N. O. (1995) Developmental regulation of the catalytic subunit of the apolipoprotein B mRNA editing enzyme (APOBEC-1) in human small intestine. J Lipid Res 36, 1664-1675.
    • (1995) J Lipid Res , vol.36 , pp. 1664-1675
    • Giannoni, F.1    Chou, S.C.2    Skarosi, S.F.3    Verp, M.S.4    Field, F.J.5    Coleman, R.A.6    Davidson, N.O.7
  • 40
    • 0029056474 scopus 로고
    • Evolutionary origins of apoB mRNA editing: Catalysis by a cytidine deaminase that has acquired a novel RNAbinding motif at its active site
    • Navaratnam, N., Bhattacharya, S., Fujino, T., Patel, D., Jarmuz, A. L., and Scott, J. (1995) Evolutionary origins of apoB mRNA editing: Catalysis by a cytidine deaminase that has acquired a novel RNAbinding motif at its active site. Cell 81, 187-195.
    • (1995) Cell , vol.81 , pp. 187-195
    • Navaratnam, N.1    Bhattacharya, S.2    Fujino, T.3    Patel, D.4    Jarmuz, A.L.5    Scott, J.6
  • 41
    • 0028997652 scopus 로고
    • Mutagenesis of apobec-1, the catalytic subunit of the mammalian apolipoprotein B mRNA editing enzyme, reveals distinct domains that mediate cytosine nucleoside deaminase, RNA binding, and RNA editing activity
    • MacGinnitie, A. J., Anant, S., and Davidson, N. O. (1995) Mutagenesis of apobec-1, the catalytic subunit of the mammalian apolipoprotein B mRNA editing enzyme, reveals distinct domains that mediate cytosine nucleoside deaminase, RNA binding, and RNA editing activity. J Biol Chem 270, 14768-14775.
    • (1995) J Biol Chem , vol.270 , pp. 14768-14775
    • MacGinnitie, A.J.1    Anant, S.2    Davidson, N.O.3
  • 42
    • 0029004350 scopus 로고
    • apobec-1, the catalyticsubunit of themammalian apolipoprotein B mRNA editing enzyme, is a novel RNA-binding protein
    • Anant, S., MacGinnitie, A. J.,and Davidson, N. O.(1995) apobec-1, the catalyticsubunit of themammalian apolipoprotein B mRNA editing enzyme, is a novel RNA-binding protein. J Biol Chem 270, 14762-14767.
    • (1995) J Biol Chem , vol.270 , pp. 14762-14767
    • Anant, S.1    MacGinnitie, A.J.2    Davidson, N.O.3
  • 43
    • 2542542827 scopus 로고    scopus 로고
    • The structure of a yeast RNA-editing deaminase provides insight into the fold and function of activation-induced deaminase and APOBEC-1
    • Xie, K., Sowden, M. P., Dance, G. S., Torelli, A. T., Smith, H. C., andWedekind, J. E. (2004) The structure of a yeast RNA-editing deaminase provides insight into the fold and function of activation-induced deaminase and APOBEC-1. Proc Natl Acad Sci USA 101, 8114-8119.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 8114-8119
    • Xie, K.1    Sowden, M.P.2    Dance, G.S.3    Torelli, A.T.4    Smith, H.C.5    Wedekind, J.E.6
  • 44
    • 12844281639 scopus 로고    scopus 로고
    • NMRstructure of the apoB mRNA stem-loop and its interaction with the C-to-U editing APOBEC1 complementary factor
    • Maris, C., Masse, J., Chester, A., Navaratnam, N., and Allain, F. H. (2005) NMRstructure of the apoB mRNA stem-loop and its interaction with the C-to-U editing APOBEC1 complementary factor. RNA 11, 173-186.
    • (2005) RNA , vol.11 , pp. 173-186
    • Maris, C.1    Masse, J.2    Chester, A.3    Navaratnam, N.4    Allain, F.H.5
  • 45
    • 0033998026 scopus 로고    scopus 로고
    • AnAU-rich sequence element (UUUN[A/U]U) downstream of the edited C in apolipoprotein B mRNA is a high-affinity binding site for Apobec-1: Binding of Apobec-1 to this motif in the 30 untranslated region of c-myc increasesmRNAstability
    • Anant, S., and Davidson, N. O. (2000) AnAU-rich sequence element (UUUN[A/U]U) downstream of the edited C in apolipoprotein B mRNA is a high-affinity binding site for Apobec-1: Binding of Apobec-1 to this motif in the 30 untranslated region of c-myc increasesmRNAstability. Mol Cell Biol 20, 1982-1992.
    • (2000) Mol Cell Biol , vol.20 , pp. 1982-1992
    • Anant, S.1    Davidson, N.O.2
  • 46
    • 31144448042 scopus 로고    scopus 로고
    • AU-rich elements and associated factors: Are there unifying principles?
    • Barreau, C., Paillard, L., and Osborne, H. B. (2005) AU-rich elements and associated factors: Are there unifying principles? Nucleic Acids Res 33, 7138-7150.
    • (2005) Nucleic Acids Res , vol.33 , pp. 7138-7150
    • Barreau, C.1    Paillard, L.2    Osborne, H.B.3
  • 48
    • 0029670088 scopus 로고    scopus 로고
    • The neurofibromatosis type I messenger RNA undergoes base-modification RNA editing
    • Skuse, G. R., Cappione, A. J., Sowden, M., Metheny, L. J., andSmith, H. C. (1996) The neurofibromatosis type I messenger RNA undergoes base-modification RNA editing. Nucleic Acids Res 24, 478-485.
    • (1996) Nucleic Acids Res , vol.24 , pp. 478-485
    • Skuse, G.R.1    Cappione, A.J.2    Sowden, M.3    Metheny, L.J.4    Smith, H.C.5
  • 49
    • 0036006807 scopus 로고    scopus 로고
    • C!U editing of neurofibromatosis 1 mRNA occurs in tumors that express both the type II transcript and apobec-1, the catalytic subunit of the apolipoprotein BmRNA-editing enzyme
    • Mukhopadhyay, D., Anant, S., Lee, R. M., Kennedy, S., Viskochil, D., and Davidson, N. O. (2002) C!U editing of neurofibromatosis 1 mRNA occurs in tumors that express both the type II transcript and apobec-1, the catalytic subunit of the apolipoprotein BmRNA-editing enzyme. Am J Hum Genet 70, 38-50.
    • (2002) Am J Hum Genet , vol.70 , pp. 38-50
    • Mukhopadhyay, D.1    Anant, S.2    Lee, R.M.3    Kennedy, S.4    Viskochil, D.5    Davidson, N.O.6
  • 50
    • 0036500884 scopus 로고    scopus 로고
    • The editosome for cytidine to uridine mRNA editing has a native complexity of 27S: identification of intracellular domains containing active and inactive editing factors
    • Sowden, M. P., Ballatori, N., Jensen, K. L., Reed, L. H., and Smith, H. C. (2002) The editosome for cytidine to uridine mRNA editing has a native complexity of 27S: identification of intracellular domains containing active and inactive editing factors. J Cell Sci 115, 1027-1039.
    • (2002) J Cell Sci , vol.115 , pp. 1027-1039
    • Sowden, M.P.1    Ballatori, N.2    Jensen, K.L.3    Reed, L.H.4    Smith, H.C.5
  • 51
    • 0025165398 scopus 로고
    • ApolipoproteinBmessengerRNAediting in the rat liver, Modulation by fasting and refeeding a high carbohydrate diet
    • Baum, C. L., Teng, B. B., and Davidson, N. O. (1990) ApolipoproteinBmessengerRNAediting in the rat liver. Modulation by fasting and refeeding a high carbohydrate diet. J Biol Chem 265, 19263-19270.
    • (1990) J Biol Chem , vol.265 , pp. 19263-19270
    • Baum, C.L.1    Teng, B.B.2    Davidson, N.O.3
  • 52
    • 0027930426 scopus 로고
    • REPRand complementation factor(s) interact to modulate rat apolipoprotein B mRNA editing in response to alterations in cellular cholesterol flux
    • Inui, Y., Giannoni, F., Funahashi, T., andDavidson, N. O. (1994)REPRand complementation factor(s) interact to modulate rat apolipoprotein B mRNA editing in response to alterations in cellular cholesterol flux. J Lipid Res. 35, 1477-1489.
    • (1994) J Lipid Res. , vol.35 , pp. 1477-1489
    • Inui, Y.1    Giannoni, F.2    Funahashi, T.3    Davidson, N.O.4
  • 53
    • 34548587816 scopus 로고    scopus 로고
    • Mousemodels as tools to exploreCtoURNAediting
    • Cho, S. J., Blanc, V., andDavidson, N. O. (2007) Mousemodels as tools to exploreCtoURNAediting. Meth Enzymol 424, 417-435.
    • (2007) Meth Enzymol , vol.424 , pp. 417-435
    • Cho, S.J.1    Blanc, V.2    Davidson, N.O.3
  • 54
    • 0030020790 scopus 로고    scopus 로고
    • Overexpression of APOBEC-1 results in mooring sequence-dependent promiscuous RNA editing
    • Sowden, M., Hamm, J. K., and Smith, H. C. (1996) Overexpression of APOBEC-1 results in mooring sequence-dependent promiscuous RNA editing. J Biol Chem 271, 3011-3017.
    • (1996) J Biol Chem , vol.271 , pp. 3011-3017
    • Sowden, M.1    Hamm, J.K.2    Smith, H.C.3
  • 55
    • 0037440117 scopus 로고    scopus 로고
    • Regulatable liver expression of the rabbit apolipoprotein B mRNA-editing enzyme catalytic polypeptide 1 (APOBEC-1) in mice lacking endogenous APOBEC-1 leads to aberrant hyperediting
    • Hersberger, M., Patarroyo-White, S., Qian, X., Arnold, K. S., Rohrer, L., Balestra, M. E., and Innerarity, T. L. (2003) Regulatable liver expression of the rabbit apolipoprotein B mRNA-editing enzyme catalytic polypeptide 1 (APOBEC-1) in mice lacking endogenous APOBEC-1 leads to aberrant hyperediting. Biochem J 369, 255-262.
    • (2003) Biochem J , vol.369 , pp. 255-262
    • Hersberger, M.1    Patarroyo-White, S.2    Qian, X.3    Arnold, K.S.4    Rohrer, L.5    Balestra, M.E.6    Innerarity, T.L.7
  • 56
    • 15844373417 scopus 로고    scopus 로고
    • Hyperediting of multiple cytidines of apolipoprotein B mRNA by APOBEC-1 requires auxiliary protein(s) but not a mooring sequence motif
    • Yamanaka, S., Poksay, K. S., Driscoll, D. M., and Innerarity, T. L. (1996) Hyperediting of multiple cytidines of apolipoprotein B mRNA by APOBEC-1 requires auxiliary protein(s) but not a mooring sequence motif. J Biol Chem 271, 11506-11510.
    • (1996) J Biol Chem , vol.271 , pp. 11506-11510
    • Yamanaka, S.1    Poksay, K.S.2    Driscoll, D.M.3    Innerarity, T.L.4
  • 58
    • 0031048641 scopus 로고    scopus 로고
    • Anovel translational repressor mRNAis edited extensively in livers containing tumors caused by the transgene expression of the apoB mRNA-editing enzyme
    • Yamanaka, S., Poksay, K. S., Arnold, K. S., and Innerarity, T. L. (1997)Anovel translational repressor mRNAis edited extensively in livers containing tumors caused by the transgene expression of the apoB mRNA-editing enzyme. Genes Dev 11, 321-333.
    • (1997) Genes Dev , vol.11 , pp. 321-333
    • Yamanaka, S.1    Poksay, K.S.2    Arnold, K.S.3    Innerarity, T.L.4
  • 60
    • 0029874937 scopus 로고    scopus 로고
    • Targeted disruption of the mouse apobec-1 gene abolishes apolipoprotein B mRNA editing and eliminates apolipoprotein B48
    • Hirano, K., Young, S. G., Farese, R.V., Jr., Ng, J., Sande, E., Warburton, C., Powell-Braxton, L. M., and Davidson, N. O. (1996) Targeted disruption of the mouse apobec-1 gene abolishes apolipoprotein B mRNA editing and eliminates apolipoprotein B48. J Biol Chem 271, 9887-9890.
    • (1996) J Biol Chem , vol.271 , pp. 9887-9890
    • Hirano, K.1    Young, S.G.2    Farese Jr, R.V.3    Ng, J.4    Sande, E.5    Warburton, C.6    Powell-Braxton, L.M.7    Davidson, N.O.8
  • 61
    • 0029900758 scopus 로고    scopus 로고
    • Apolipoprotein B RNA editing enzyme-deficient mice are viable despite alterations in lipoprotein metabolism
    • Morrison, J. R., Paszty, C., Stevens, M. E., Hughes, S. D., Forte, T., Scott, J., and Rubin, E. M. (1996) Apolipoprotein B RNA editing enzyme-deficient mice are viable despite alterations in lipoprotein metabolism. Proc Natl Acad Sci USA 93, 7154-7159.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 7154-7159
    • Morrison, J.R.1    Paszty, C.2    Stevens, M.E.3    Hughes, S.D.4    Forte, T.5    Scott, J.6    Rubin, E.M.7
  • 62
    • 0035875156 scopus 로고    scopus 로고
    • Superior role of apolipoprotein B48 over apolipoprotein B100 in chylomicron assembly and fat absorption: An investigation of apobec-1 knock-out and wild-type mice
    • Kendrick, J. S., Chan, L., and Higgins, J. A. (2001) Superior role of apolipoprotein B48 over apolipoprotein B100 in chylomicron assembly and fat absorption: An investigation of apobec-1 knock-out and wild-type mice. Biochem J 356, 821-827.
    • (2001) Biochem J , vol.356 , pp. 821-827
    • Kendrick, J.S.1    Chan, L.2    Higgins, J.A.3
  • 63
    • 0141813341 scopus 로고    scopus 로고
    • Intestinal lipoprotein assembly in apobec-1-/- mice reveals subtle alterations in triglyceride secretion coupled with a shift to larger lipoproteins
    • Xie, Y., Nassir, F., Luo, J., Buhman, K., and Davidson, N. O. (2003) Intestinal lipoprotein assembly in apobec-1-/- mice reveals subtle alterations in triglyceride secretion coupled with a shift to larger lipoproteins. Am J Physiol Gastrointest Liver Physiol 285, G735-G746.
    • (2003) Am J Physiol Gastrointest Liver Physiol , vol.285
    • Xie, Y.1    Nassir, F.2    Luo, J.3    Buhman, K.4    Davidson, N.O.5
  • 64
    • 0031927755 scopus 로고    scopus 로고
    • A mouse model of human familial hypercholesterolemia: Markedly elevated low density lipoprotein cholesterol levels and severe atherosclerosis on a low-fat chow diet
    • Powell-Braxton, L., Veniant, M., Latvala, R. D., Hirano, K. I., Won, W. B., Ross, J., Dybdal, N., Zlot, C. H., Young, S. G., and Davidson, N. O. (1998) A mouse model of human familial hypercholesterolemia: Markedly elevated low density lipoprotein cholesterol levels and severe atherosclerosis on a low-fat chow diet. Nat Med 4, 934-938.
    • (1998) Nat Med , vol.4 , pp. 934-938
    • Powell-Braxton, L.1    Veniant, M.2    Latvala, R.D.3    Hirano, K.I.4    Won, W.B.5    Ross, J.6    Dybdal, N.7    Zlot, C.H.8    Young, S.G.9    Davidson, N.O.10
  • 65
    • 0036202559 scopus 로고    scopus 로고
    • Identification of domains in apobec-1 complementation factor required for RNA binding and apolipoprotein-B mRNA editing
    • Mehta, A., and Driscoll, D. M. (2002) Identification of domains in apobec-1 complementation factor required for RNA binding and apolipoprotein-B mRNA editing. RNA 8, 69-82.
    • (2002) RNA , vol.8 , pp. 69-82
    • Mehta, A.1    Driscoll, D.M.2
  • 66
    • 0028129989 scopus 로고
    • Conserved structures and diversity of functions of RNA-binding proteins
    • Burd, C. G., and Dreyfuss, G. (1994) Conserved structures and diversity of functions of RNA-binding proteins. Science 265, 615-621.
    • (1994) Science , vol.265 , pp. 615-621
    • Burd, C.G.1    Dreyfuss, G.2
  • 67
    • 0347052885 scopus 로고    scopus 로고
    • Identification of novel alternative splice variants of APOBEC-1 complementation factor with different capacities to support apolipoprotein B mRNA editing
    • Sowden, M. P., Lehmann, D. M., Lin, X., Smith, C. O., and Smith, H. C. (2004) Identification of novel alternative splice variants of APOBEC-1 complementation factor with different capacities to support apolipoprotein B mRNA editing. J Biol Chem 279, 197-206.
    • (2004) J Biol Chem , vol.279 , pp. 197-206
    • Sowden, M.P.1    Lehmann, D.M.2    Lin, X.3    Smith, C.O.4    Smith, H.C.5
  • 68
    • 33846122238 scopus 로고    scopus 로고
    • ApoB mRNA editing is mediated by a coordinated modulation of multiple apoB mRNA editing enzyme components
    • Chen, Z., Eggerman, T. L., and Patterson, A. P. (2007) ApoB mRNA editing is mediated by a coordinated modulation of multiple apoB mRNA editing enzyme components. Am J Physiol Gastrointest Liver Physiol 292, G53-G65.
    • (2007) Am J Physiol Gastrointest Liver Physiol , vol.292
    • Chen, Z.1    Eggerman, T.L.2    Patterson, A.P.3
  • 69
    • 0033638939 scopus 로고    scopus 로고
    • Direct effects of growth hormone on production and secretion of apolipoprotein B from rat hepatocytes
    • Linden, D., Sjoberg, A., Asp, L., Carlsson, L., and Oscarsson, J. (2000) Direct effects of growth hormone on production and secretion of apolipoprotein B from rat hepatocytes. Am J Physiol Endocrinol Metab 279, E1335-E1346.
    • (2000) Am J Physiol Endocrinol Metab , vol.279
    • Linden, D.1    Sjoberg, A.2    Asp, L.3    Carlsson, L.4    Oscarsson, J.5
  • 70
    • 0028900372 scopus 로고
    • Tissue-specific, developmental and nutritional regulation of the gene encoding the catalytic subunit of the rat apolipoprotein B mRNA editing enzyme: Functional role in the modulation of apoB mRNA editing
    • Funahashi, T., Giannoni, F., DePaoli, A. M., Skarosi, S. F., andDavidson, N. O. (1995)Tissue-specific, developmental and nutritional regulation of the gene encoding the catalytic subunit of the rat apolipoprotein B mRNA editing enzyme: Functional role in the modulation of apoB mRNA editing. J Lipid Res 36, 414-428.
    • (1995) J Lipid Res , vol.36 , pp. 414-428
    • Funahashi, T.1    Giannoni, F.2    DePaoli, A.M.3    Skarosi, S.F.4    Davidson, N.O.5
  • 71
    • 0035930937 scopus 로고    scopus 로고
    • Ethanol stimulates apolipoprotein B mRNA editing in the absence of de novo RNA or protein synthesis
    • Giangreco, A., Sowden, M. P., Mikityansky, I., and Smith, H. C. (2001) Ethanol stimulates apolipoprotein B mRNA editing in the absence of de novo RNA or protein synthesis. Biochem Biophys Res Commun 289, 1162-1167.
    • (2001) Biochem Biophys Res Commun , vol.289 , pp. 1162-1167
    • Giangreco, A.1    Sowden, M.P.2    Mikityansky, I.3    Smith, H.C.4
  • 72
    • 33746281453 scopus 로고    scopus 로고
    • Metabolic regulation of apoB mRNA editing is associated with phosphorylation of APOBEC-1 complementation factor
    • Lehmann, D. M., Galloway, C. A., Sowden, M. P., and Smith, H. C. (2006)Metabolic regulation of apoB mRNA editing is associated with phosphorylation of APOBEC-1 complementation factor. Nucleic Acids Res 34, 3299-3308.
    • (2006) Nucleic Acids Res , vol.34 , pp. 3299-3308
    • Lehmann, D.M.1    Galloway, C.A.2    Sowden, M.P.3    Smith, H.C.4
  • 75
    • 0037245474 scopus 로고    scopus 로고
    • Coupled mRNAstabilization and translational silencing of cyclooxygenase-2 by a novelRNAbinding protein, CUGBP2
    • Mukhopadhyay, D., Houchen, C.W., Kennedy, S., Dieckgraefe, B. K., and Anant, S. (2003) Coupled mRNAstabilization and translational silencing of cyclooxygenase-2 by a novelRNAbinding protein, CUGBP2. Mol Cell 11, 113-126.
    • (2003) Mol Cell , vol.11 , pp. 113-126
    • Mukhopadhyay, D.1    Houchen, C.W.2    Kennedy, S.3    Dieckgraefe, B.K.4    Anant, S.5
  • 76
    • 0028838519 scopus 로고
    • Ethanol modulates apolipoprotein B mRNA editing in the rat
    • Lau, P. P., Cahill, D. J., Zhu, H. J., and Chan, L. (1995) Ethanol modulates apolipoprotein B mRNA editing in the rat. J Lipid Res 36, 2069-2078.
    • (1995) J Lipid Res , vol.36 , pp. 2069-2078
    • Lau, P.P.1    Cahill, D.J.2    Zhu, H.J.3    Chan, L.4
  • 77
    • 0034101197 scopus 로고    scopus 로고
    • The 30 untranslated region of messengerRNA:Amolecular 'hotspot' for pathology?
    • Conne, B., Stutz, A., andVassalli, J. D. (2000) The 30 untranslated region of messengerRNA:Amolecular 'hotspot' for pathology? Nat Med 6, 637-641.
    • (2000) Nat Med , vol.6 , pp. 637-641
    • Conne, B.1    Stutz, A.2    Vassalli, J.D.3
  • 78
    • 0028788194 scopus 로고
    • AU-rich elements: Characterization and importance in mRNA degradation
    • Chen, C. Y. and Shyu, A. B. (1995) AU-rich elements: Characterization and importance in mRNA degradation. Trends Biochem Sci 20, 465-470.
    • (1995) Trends Biochem Sci , vol.20 , pp. 465-470
    • Chen, C.Y.1    Shyu, A.B.2
  • 79
    • 0025769412 scopus 로고
    • Primary response genes induced by growth factors and tumor promoters
    • Herschman, H. R. (1991) Primary response genes induced by growth factors and tumor promoters. Annu Rev Biochem 60, 281-319.
    • (1991) Annu Rev Biochem , vol.60 , pp. 281-319
    • Herschman, H.R.1
  • 80
    • 0029801756 scopus 로고    scopus 로고
    • Transcriptional and translational control of TNF-alpha gene expression inhumanmonocytes by major histocompatibility complex class II ligands
    • Espel, E., Garcia-Sanz, J. A., Aubert, V., Menoud, V., Sperisen, P., Fernandez, N., and Spertini, F. (1996)Transcriptional and translational control of TNF-alpha gene expression inhumanmonocytes by major histocompatibility complex class II ligands. Eur J Immunol 26, 2417-2424.
    • (1996) Eur J Immunol , vol.26 , pp. 2417-2424
    • Espel, E.1    Garcia-Sanz, J.A.2    Aubert, V.3    Menoud, V.4    Sperisen, P.5    Fernandez, N.6    Spertini, F.7
  • 81
    • 16844362149 scopus 로고    scopus 로고
    • Post-transcriptional regulation in cancer
    • Audic, Y., and Hartley, R. S. (2004) Post-transcriptional regulation in cancer. Biol Cell 96, 479-498.
    • (2004) Biol Cell , vol.96 , pp. 479-498
    • Audic, Y.1    Hartley, R.S.2
  • 83
    • 0034040576 scopus 로고    scopus 로고
    • Lipopolysaccharide is radioprotective in the mouse intestine through a prostaglandin-mediated mechanism
    • Riehl, T., Cohn, S., Tessner, T., Schloemann, S., and Stenson, W. F. (2000) Lipopolysaccharide is radioprotective in the mouse intestine through a prostaglandin-mediated mechanism. Gastroenterology 118, 1106-1116.
    • (2000) Gastroenterology , vol.118 , pp. 1106-1116
    • Riehl, T.1    Cohn, S.2    Tessner, T.3    Schloemann, S.4    Stenson, W.F.5
  • 84
    • 0032567649 scopus 로고    scopus 로고
    • Dissociation of basal turnover and cytokine-induced transcript stabilization of the human cyclooxygenase-2 mRNA by mutagenesis of the 30-untranslated region
    • Gou, Q., Liu, C. H., Ben-Av, P., and Hla, T. (1998) Dissociation of basal turnover and cytokine-induced transcript stabilization of the human cyclooxygenase-2 mRNA by mutagenesis of the 30-untranslated region. Biochem Biophys Res Commun 242, 508-512.
    • (1998) Biochem Biophys Res Commun , vol.242 , pp. 508-512
    • Gou, Q.1    Liu, C.H.2    Ben-Av, P.3    Hla, T.4
  • 85
    • 0035933736 scopus 로고    scopus 로고
    • The 30-untranslated region ofmurine cyclooxygenase-2 contains multiple regulatory elements that alter message stability and translational efficiency
    • Cok, S. J., andMorrison, A. R. (2001) The 30-untranslated region ofmurine cyclooxygenase-2 contains multiple regulatory elements that alter message stability and translational efficiency. J Biol Chem 276, 23179-23185.
    • (2001) J Biol Chem , vol.276 , pp. 23179-23185
    • Cok, S.J.1    Morrison, A.R.2
  • 86
    • 33846653409 scopus 로고    scopus 로고
    • Prostaglandins and epithelial response to injury
    • Stenson, W. F. (2007) Prostaglandins and epithelial response to injury. Curr Opin Gastroenterol 23, 107-110.
    • (2007) Curr Opin Gastroenterol , vol.23 , pp. 107-110
    • Stenson, W.F.1
  • 87
    • 0027993458 scopus 로고
    • Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas
    • Eberhart, C. E., Coffey, R. J., Radhika, A., Giardiello, F. M., Ferrenbach, S., and DuBois, R. N. (1994) Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas. Gastroenterology 107, 1183-1188.
    • (1994) Gastroenterology , vol.107 , pp. 1183-1188
    • Eberhart, C.E.1    Coffey, R.J.2    Radhika, A.3    Giardiello, F.M.4    Ferrenbach, S.5    DuBois, R.N.6
  • 88
    • 0029913633 scopus 로고    scopus 로고
    • Increased cyclooxygenase-2 levels in carcinogen-induced rat colonic tumors
    • DuBois, R. N., Radhika, A., Reddy, B. S., and Entingh, A. J. (1996) Increased cyclooxygenase-2 levels in carcinogen-induced rat colonic tumors. Gastroenterology 110, 1259-1262.
    • (1996) Gastroenterology , vol.110 , pp. 1259-1262
    • DuBois, R.N.1    Radhika, A.2    Reddy, B.S.3    Entingh, A.J.4
  • 91
  • 93
    • 5044232017 scopus 로고    scopus 로고
    • Liver regeneration: From myth to mechanism
    • Taub, R. (2004) Liver regeneration: From myth to mechanism. Nat Rev Mol Cell Biol 5, 836-847.
    • (2004) Nat Rev Mol Cell Biol , vol.5 , pp. 836-847
    • Taub, R.1
  • 94
    • 0029780653 scopus 로고    scopus 로고
    • N-nitrosodiethylamine mechanistic data and risk assessment: Bioactivation, DNA-adduct formation, mutagenicity, and tumor initiation
    • Verna, L., Whysner, J., andWilliams, G. M. (1996) N-nitrosodiethylamine mechanistic data and risk assessment: Bioactivation, DNA-adduct formation, mutagenicity, and tumor initiation. Pharmacol Ther 71, 57-81.
    • (1996) Pharmacol Ther , vol.71 , pp. 57-81
    • Verna, L.1    Whysner, J.2    Williams, G.M.3
  • 95
    • 0037462454 scopus 로고    scopus 로고
    • Liver tumor development, c-Jun antagonizes the proapoptotic activity of p53
    • Eferl, R., Ricci, R., Kenner, L., Zenz, R., David, J. P., Rath, M., andWagner, E. F. (2003) Liver tumor development. c-Jun antagonizes the proapoptotic activity of p53. Cell 112, 181-192.
    • (2003) Cell , vol.112 , pp. 181-192
    • Eferl, R.1    Ricci, R.2    Kenner, L.3    Zenz, R.4    David, J.P.5    Rath, M.6    Wagner, E.F.7
  • 96
    • 0025361155 scopus 로고
    • Detection of the anti-Hu antibody in the serum of patients with small cell lung cancer-aquantitative western blot analysis
    • Dalmau, J., Furneaux, H. M., Gralla, R. J., Kris, M. G., and Posner, J. B. (1990) Detection of the anti-Hu antibody in the serum of patients with small cell lung cancer-aquantitative western blot analysis. Ann Neurol 27, 544-552.
    • (1990) Ann Neurol , vol.27 , pp. 544-552
    • Dalmau, J.1    Furneaux, H.M.2    Gralla, R.J.3    Kris, M.G.4    Posner, J.B.5
  • 97
    • 0026094583 scopus 로고
    • HuD, a paraneoplastic encephalomyelitis antigen, contains RNA-binding domains and is homologous to Elav and Sex-lethal
    • Szabo, A., Dalmau, J., Manley, G., Rosenfeld, M., Wong, E., Henson, J., Posner, J. B., and Furneaux, H. M. (1991) HuD, a paraneoplastic encephalomyelitis antigen, contains RNA-binding domains and is homologous to Elav and Sex-lethal. Cell 67, 325-333.
    • (1991) Cell , vol.67 , pp. 325-333
    • Szabo, A.1    Dalmau, J.2    Manley, G.3    Rosenfeld, M.4    Wong, E.5    Henson, J.6    Posner, J.B.7    Furneaux, H.M.8
  • 99
    • 0032431026 scopus 로고    scopus 로고
    • HNS, a nuclear-cytoplasmic shuttling sequence in HuR
    • Fan, X. C., and Steitz, J. A. (1998) HNS, a nuclear-cytoplasmic shuttling sequence in HuR. Proc Natl Acad Sci USA 95, 15293-15298.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 15293-15298
    • Fan, X.C.1    Steitz, J.A.2
  • 100
    • 0034657686 scopus 로고    scopus 로고
    • HuRregulates cyclinAand cyclin B1 mRNA stability during cell proliferation
    • Wang, W., Caldwell, M. C., Lin, S., Furneaux, H., and Gorospe, M. (2000)HuRregulates cyclinAand cyclin B1 mRNA stability during cell proliferation. EMBO J 19, 2340-2350.
    • (2000) EMBO J , vol.19 , pp. 2340-2350
    • Wang, W.1    Caldwell, M.C.2    Lin, S.3    Furneaux, H.4    Gorospe, M.5
  • 101
    • 0034908634 scopus 로고    scopus 로고
    • Loss ofHuRis linked to reduced expression of proliferative genes during replicative senescence
    • Wang, W., Yang, X., Cristofalo, V. J., Holbrook, N. J., and Gorospe, M. (2001) Loss ofHuRis linked to reduced expression of proliferative genes during replicative senescence. Mol Cell Biol 21, 5889-5898.
    • (2001) Mol Cell Biol , vol.21 , pp. 5889-5898
    • Wang, W.1    Yang, X.2    Cristofalo, V.J.3    Holbrook, N.J.4    Gorospe, M.5
  • 102
    • 0035213198 scopus 로고    scopus 로고
    • Altered expression of the mRNA stability factor HuR promotes cyclooxygenase-2 expression in colon cancer cells
    • Dixon, D. A., Tolley, N. D., King, P. H., Nabors, L. B., McIntyre, T. M., Zimmerman, G. A., and Prescott, S. M. (2001) Altered expression of the mRNA stability factor HuR promotes cyclooxygenase-2 expression in colon cancer cells. J Clin Invest 108, 1657-1665.
    • (2001) J Clin Invest , vol.108 , pp. 1657-1665
    • Dixon, D.A.1    Tolley, N.D.2    King, P.H.3    Nabors, L.B.4    McIntyre, T.M.5    Zimmerman, G.A.6    Prescott, S.M.7
  • 103
    • 2542596992 scopus 로고    scopus 로고
    • Roles ofAUF1 isoforms, HuR and BRF1 in ARE-dependent mRNA turnover studied by RNA interference
    • Raineri, I., Wegmueller, D., Gross, B., Certa, U., and Moroni, C. (2004) Roles ofAUF1 isoforms, HuR and BRF1 in ARE-dependent mRNA turnover studied by RNA interference. Nucleic Acids Res 32, 1279-1288.
    • (2004) Nucleic Acids Res , vol.32 , pp. 1279-1288
    • Raineri, I.1    Wegmueller, D.2    Gross, B.3    Certa, U.4    Moroni, C.5
  • 104
    • 9144266290 scopus 로고    scopus 로고
    • Overexpression of the embryonic-lethal abnormal vision-like protein HuR in ovarian carcinoma is a prognostic factor and is associated with increased cyclooxygenase 2 expression
    • Denkert, C., Weichert, W., Pest, S., Koch, I., Licht, D., Kobel, M., Reles, A., Sehouli, J., Dietel, M., and Hauptmann, S. (2004) Overexpression of the embryonic-lethal abnormal vision-like protein HuR in ovarian carcinoma is a prognostic factor and is associated with increased cyclooxygenase 2 expression. Cancer Res 64, 189-195.
    • (2004) Cancer Res , vol.64 , pp. 189-195
    • Denkert, C.1    Weichert, W.2    Pest, S.3    Koch, I.4    Licht, D.5    Kobel, M.6    Reles, A.7    Sehouli, J.8    Dietel, M.9    Hauptmann, S.10
  • 105
    • 0033933196 scopus 로고    scopus 로고
    • Differential expression and localization of the mRNA binding proteins, AU-rich element mRNA binding protein (AUF1) and Hu antigen R (HuR), in neoplastic lung tissue
    • Blaxall, B. C., Dwyer-Nield, L. D., Bauer, A. K., Bohlmeyer, T. J., Malkinson, A. M. and Port, J. D. (2000) Differential expression and localization of the mRNA binding proteins, AU-rich element mRNA binding protein (AUF1) and Hu antigen R (HuR), in neoplastic lung tissue. Mol Carcinog 28, 76-83.
    • (2000) Mol Carcinog , vol.28 , pp. 76-83
    • Blaxall, B.C.1    Dwyer-Nield, L.D.2    Bauer, A.K.3    Bohlmeyer, T.J.4    Malkinson, A.M.5    Port, J.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.