Superior role of apolipoprotein B48 over apolipoprotein B100 in chylomicron assembly and fat absorption: An investigation of apobec-1 knock-out and wild-type mice

Biochemical Journal

Volumn 356, Issue 3, 2001, Pages 821-827

  Kendrick, J S ^a   Chan, L ^a   Higgins, J A ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Electron microscopy; Intracellular events; Isolated enterocytes; mRNA editing; Triacylglycerol

Indexed keywords

APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 1; APOLIPOPROTEIN B100; APOLIPOPROTEIN B48; CHYLOMICRON; MESSENGER RNA; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DIETARY INTAKE; FAT INTAKE; FEEDING; INTESTINE ABSORPTION; INTESTINE CELL; LIPID ABSORPTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; RNA EDITING; STIMULATION; SYNTHESIS;

ANIMALS; APOLIPOPROTEIN B-100; APOLIPOPROTEIN B-48; APOLIPOPROTEINS B; CHYLOMICRONS; CYTIDINE DEAMINASE; DIETARY FATS; INTESTINAL ABSORPTION; INTESTINE, SMALL; MICE; MICE, KNOCKOUT; MICROSCOPY, ELECTRON;

ANIMALIA; MAMMALIA;

EID: 0035875156     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3560821     Document Type: Article

References (20)

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5. Complete phenotypic characterisation of apobec-1 knockout mice with a wild type genetic background and restoration of apolipoprotein B mRNA editing by somatic transfer of apobec-1
6. Increased dietary triacylglycerol markedly enhances the ability of isolated rabbit enterocytes to secrete chylomicrons: An effect related to the dietary laity acid composition
7. A novel method for the rapid separation of plasma lipoproteins using self-generating gradients of iodixanol
8. Studies on fat digestion, absorption and transport in the suckling rat IV rates of triacylglycerol secretion by intestine and liver
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10. Isolated rabbit enterocytes as a model system for investigations of chylomicron assembly and secretion
11. Intracellular events in the assembly of chylomicrons in rabbit enterocytes
12. Separation of the intracellular secretory compartment of rat liver and isolated rat hepatocytes in a single step using self-generating gradients of iodixanol
13. Targeted disruption of the mouse apobec-1 gene abolishes apolipoprotein B mRNA editing and eliminates apolipoprotein B48
14. Apolipoprotein B RNA editing enzyme deficient mice are viable despite alterations in lipoprotein metabolism
15. Effects of apo-E deficiency on plasma lipid levels in mice lacking apobec-1
16. A genetic model for absent chylomicron formation: Mice producing apolipoprotein B in the liver but not the intestine
17. Chylomicron sized particles are formed in the setting of apolipoprotein B deficiency
18. Intracellular movement of triacylglycerol in the intestine
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