Direct effects of growth hormone on production and secretion of apolipoprotein B from rat hepatocytes

American Journal of Physiology - Endocrinology and Metabolism

Volumn 279, Issue 6 42-6, 2000, Pages

  Lindén, Daniel ^a   Sjöberg, Anders ^a   Asp, Lennart ^a   Carlsson, Linda ^a   Oscarsson, Jan ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Apolipoprotein B 100; Apolipoprotein B 48; Fatty acids; Insulin; Very low density lipoproteins

Indexed keywords

APOLIPOPROTEIN B; APOLIPOPROTEIN B100; APOLIPOPROTEIN B48; FATTY ACID; OLEIC ACID; VERY LOW DENSITY LIPOPROTEIN;

ANIMAL CELL; ARTICLE; DEAMINATION; ENZYME ACTIVITY; FATTY ACID TRANSPORT; GROWTH HORMONE RELEASE; INSULIN RESISTANCE; LIPOPROTEIN METABOLISM; LIVER CELL; LIVER PERFUSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DEGRADATION; PROTEIN PROCESSING; RAT; RNA EDITING;

EID: 0033638939     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.2000.279.6.e1335     Document Type: Article

References (50)

1. The effects of glucocorticoids on insulin-stimulated lipogenesis in primary cultures of rat hepatocytes
2. Apolipoprotein B messenger RNA editing in the rat liver: Modulation by fasting and refeeding a high carbohydrate diet
3. Support of cultured hepatocytes by a laminin-rich gel: Evidence for functionally significant subendothelial matrix in normal rat liver
4. A rapid method of total lipid extraction and purification
5. Metabolic actions of pituitary growth hormone I. Inhibition of acetyl CoA carboxylase by human growth hormone and a carboxyl terminal part sequence acting through a second messenger
6. Hormonal regulation of liver fatty acid-binding protein in vivo and in vitro: Effects of growth hormone and insulin
7. Apolipoprotein B-48 is the product of a messenger RNA with an organ-specific in-frame stop codon
8. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
9. Effects of growth hormone (GH) replacement therapy on very low density lipoprotein apolipoprotein B100 kinetics in patients with adult GH deficiency: A stable isotope study
10. Effect of growth hormone on fatty acid oxidation: Growth hormone increases the activity of 2,4-dienoyl-CoA reductase in mitochondria
11. Developmental coordinate expression of triacylglycerol and small molecular weight apoB synthesis and secretion by rat hepatocytes
12. Insulin-like growth factor-1 binding in hepatocytes from human liver, human hepatoma, and normal, regenerating, and fetal rat liver
13. Selective recruitment of apoB-48 for the assembly of VLDL in rat triglyceride-enriched hepatocytes
14. Effect of growth hormone on carbohydrate and lipid metabolism
15. Thyroid hormone modulates the introduction of a stop codon in rat liver apolipoprotein B messenger RNA
16. The growth hormone dependent decrease in hepatic fatty acid synthase mRNA is the result of a decrease in gene transcription
17. Stimulation of in vitro triglyceride synthesis in the rat hepatocyte by growth hormone treatment in vivo
18. In vivo growth hormone treatment stimulates secretion of very low density lipoprotein by the isolated perfused rat liver
19. Mechanisms by which somatotropin decreases adipose tissue growth
20. Induction of the estrogen receptor by growth hormone and glucocorticoid substitution in primary cultures of rat hepatocytes
21. Assembly and secretion of hepatic very-low-density lipoprotein
22. Apolipoprotein B synthesis by human liver and intestine in vitro
23. Influence of gonadal steroids on age- and sex-related secretory patterns of growth hormone in the rat
24. Effect of 1 year growth hormone therapy on serum lipoprotein levels in growth hormone deficient adults: Influence of gender and apo(a) and apoE phenotypes
25. A simple, rapid, and sensitive DNA assay procedure
26. Fasting decreases apolipoprotein B mRNA editing and the secretion of small molecular weight apoB by rat hepatocytes: Evidence that the total amount of apoB secreted is regulated post-transcriptionally
27. Fatty acid regulation of very low density lipoprotein production
28. Dexamethasone enhanced by insulin, but not thyroid hormones stimulates apolipoprotein B mRNA editing in cultured rat hepatocytes depending on the developmental stage
29. Mechanism of estrogen and progesterone effects on lipid and carbohydrate metabolism: Alteration in the insulin:glucagon molar ratio and hepatic enzyme activity
30. The assembly and secretion of apolipoprotein B-containing lipoproteins
31. Differential effects of continuous versus intermittent administration of growth hormone to hypophysectomized female rats on serum lipoproteins and their apoproteins
32. Effects of growth hormone on lipoprotein lipase and hepatic lipase
33. Growth hormone specifically stimulates the expression of low density lipoprotein receptors in human hepatoma cells
34. Effects of growth hormone on insulin release in the rat
35. Insulin antagonises the growth hormone-mediated increase in the activity of phosphatidate phosphohydrolase in isolated rat hepatocytes
36. A novel form of tissue specific RNA processing produces apolipoprotein B-48 in intestine
37. Importance of growth hormone for the induction of hepatic low density lipoprotein receptors
38. Effects of oleic acid on the biosynthesis of lipoprotein apoproteins and distribution into the very-low-density lipoprotein by the isolated perfused rat liver
39. Mode of growth hormone administration influences triacylglycerol synthesis and assembly of apolipoproteinB-containing lipoproteins in cultured rat hepatocytes
40. Effects of growth hormone on apolipoprotein B (apoB) messenger ribonucleic acid editing, and apoB-48 and apoB- 100 synthesis and secretion in the rat liver
41. Insulin-like growth factor-I and growth hormone have different effects on serum lipoproteins and secretion of lipoproteins from cultured rat hepatocytes
42. Insulin regulation of triglyceride-rich lipoprotein synthesis and secretion
43. Hormonal and nutritional stimuli modulate apolipoprotein B mRNA editing in mouse liver
44. Growth hormone induces CCAAT/enhancer binding protein α (C/EBPα) in cultured rat hepatocytes
45. Insulin promotes the biosynthesis and secretion of apolipoprotein B-48 by altering apolipoprotein B mRNA editing
46. Growth hormone (GH) regulation of cytochrome P-450IIC12, insulin-like growth factor-I (IGF-I), and GH receptor messenger RNA expression in primary rat hepatocytes: A hormonal interplay with insulin, IGF-I, and thyroid hormone
47. The role of the LDL receptor in apolipoprotein B secretion
48. Hepatic lipid metabolism in experimental diabetes. V. The effect of concentration of oleate on metabolism of triglycerides and on ketogenesis
49. Pulse-chase studies of the synthesis of apolipoproteinB in a human hepatoma cell line, Hep G2
50. Apolipoprotein B mRNA editing: Validation of a sensitive assay and developmental biology of RNA editing in the rat