메뉴 건너뛰기




Volumn , Issue , 2010, Pages 757-780

Wet Granulation Processes

Author keywords

Two near elastic granules collision basis for coalescence rebound criteria; Wet granulation processes, and mechanisms in wet granulation liquid, forming wet agglomerates; Wet granule deformation extremes and breakage behavior in diametrical compression

Indexed keywords


EID: 84889289994     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470882221.ch39     Document Type: Chapter
Times cited : (6)

References (108)
  • 1
    • 0035806257 scopus 로고    scopus 로고
    • Nucleation, growth and breakage phenomena in agitated wet granulation processes: a review
    • Iveson SM, Litster JD, Hapgood KP, Ennis BJ. Nucleation, growth and breakage phenomena in agitated wet granulation processes: a review. Powder Technol. 2001;117(1-2): 3-39.
    • (2001) Powder Technol. , vol.117 , Issue.1-2 , pp. 3-39
    • Iveson, S.M.1    Litster, J.D.2    Hapgood, K.P.3    Ennis, B.J.4
  • 2
    • 0032125567 scopus 로고    scopus 로고
    • An investigation into the kinetics of liquid distribution and growth in high shear mixer agglomeration
    • Knight PC, Instone T, Pearson JMK, Hounslow MJ. An investigation into the kinetics of liquid distribution and growth in high shear mixer agglomeration. Powder Technol. 1998;97:246-257.
    • (1998) Powder Technol. , vol.97 , pp. 246-257
    • Knight, P.C.1    Instone, T.2    Pearson, J.M.K.3    Hounslow, M.J.4
  • 5
    • 0034694397 scopus 로고    scopus 로고
    • Direct evidence of heterogeneity during high-shear granulation
    • Scott AC, Hounslow MJ, Instone T. Direct evidence of heterogeneity during high-shear granulation. Powder Technol. 1999;113:215-213.
    • (1999) Powder Technol. , vol.113 , pp. 215-213
    • Scott, A.C.1    Hounslow, M.J.2    Instone, T.3
  • 6
    • 58749085081 scopus 로고    scopus 로고
    • Single drop behaviour in a high shear granulator
    • Chouk V, Reynolds G, Hounslow M, Salman A. Single drop behaviour in a high shear granulator. Powder Technol. 2009;189(2):357-364.
    • (2009) Powder Technol. , vol.189 , Issue.2 , pp. 357-364
    • Chouk, V.1    Reynolds, G.2    Hounslow, M.3    Salman, A.4
  • 7
    • 33746933851 scopus 로고    scopus 로고
    • Amodel for the spray zone in early-stage fluidized bed granulation.
    • Schaafsma SH,Vonk P,KossenNWF, HoffmannAC.Amodel for the spray zone in early-stage fluidized bed granulation. AIChE J. 2006;52(8):2736-2741.
    • (2006) AIChE J. , vol.52 , Issue.8 , pp. 2736-2741
    • Schaafsma, S.H.1    Vonk, P.2    Kossen, N.W.F.3    Hoffmann, A.C.4
  • 10
    • 0037326265 scopus 로고    scopus 로고
    • Nucleation regime map for liquid bound granules
    • Hapgood KP, Litster JD, Smith R. Nucleation regime map for liquid bound granules. AIChE J. 2003;49(2):350-361.
    • (2003) AIChE J. , vol.49 , Issue.2 , pp. 350-361
    • Hapgood, K.P.1    Litster, J.D.2    Smith, R.3
  • 12
    • 2342455847 scopus 로고    scopus 로고
    • Dimensionless spray flux in wet granulation: Monte-Carlo simulations and experimental validation
    • Hapgood KP, Litster JD, White ET, Mort PR, Jones DG. Dimensionless spray flux in wet granulation: Monte-Carlo simulations and experimental validation. Powder Technol. 2004;141(1-2):20-30.
    • (2004) Powder Technol. , vol.141 , Issue.1-2 , pp. 20-30
    • Hapgood, K.P.1    Litster, J.D.2    White, E.T.3    Mort, P.R.4    Jones, D.G.5
  • 14
    • 67649995614 scopus 로고    scopus 로고
    • Rewetting effects and droplet motion on partially wetted powder surfaces
    • Hapgood KP, Nguyen TH, Hauw S, Iveson SM, Shen W. Rewetting effects and droplet motion on partially wetted powder surfaces. AIChE J. 2009;55(6):1402-1415.
    • (2009) AIChE J. , vol.55 , Issue.6 , pp. 1402-1415
    • Hapgood, K.P.1    Nguyen, T.H.2    Hauw, S.3    Iveson, S.M.4    Shen, W.5
  • 16
    • 0003887606 scopus 로고
    • Modelling Axisymmetric Flows: Dynamics of Films, Jets, and Drops
    • Chapter 8, Academic Press, San Diego
    • Middleman S. Modelling Axisymmetric Flows: Dynamics of Films, Jets, and Drops, Chapter 8, Academic Press, San Diego, 1995, p. 299.
    • (1995) , pp. 299
    • Middleman, S.1
  • 17
    • 36248989125 scopus 로고    scopus 로고
    • Influence of liquid binder dispersion on agglomeration in an intensive mixer
    • Ax K, Feise H, Sochon R, Hounslow M, Salman A. Influence of liquid binder dispersion on agglomeration in an intensive mixer. Powder Technol. 2008;179(3):190-194.
    • (2008) Powder Technol. , vol.179 , Issue.3 , pp. 190-194
    • Ax, K.1    Feise, H.2    Sochon, R.3    Hounslow, M.4    Salman, A.5
  • 18
    • 0003416392 scopus 로고    scopus 로고
    • Nucleation and Binder Dispersion in Wet Granulation
    • PhD thesis, Department of Chemical Engineering, University of Queensland, Brisbane, Australia
    • Hapgood KP. Nucleation and Binder Dispersion in Wet Granulation, PhD thesis, Department of Chemical Engineering, University of Queensland, Brisbane, Australia, 2000.
    • (2000)
    • Hapgood, K.P.1
  • 20
    • 0026396882 scopus 로고
    • Growth mechanism and the dependence of granule size on drop size in fluidised bed granulation
    • Waldie B. Growth mechanism and the dependence of granule size on drop size in fluidised bed granulation. Chem. Eng. Sci. 1991;46(11):2781-2785.
    • (1991) Chem. Eng. Sci. , vol.46 , Issue.11 , pp. 2781-2785
    • Waldie, B.1
  • 21
    • 0142026019 scopus 로고    scopus 로고
    • Quantifying liquid coverage and powder flux in high-shear granulators
    • Plank R, Diehl B, Grinstead H, Zega J. Quantifying liquid coverage and powder flux in high-shear granulators. Powder Technol. 2003;134(3):223-234.
    • (2003) Powder Technol. , vol.134 , Issue.3 , pp. 223-234
    • Plank, R.1    Diehl, B.2    Grinstead, H.3    Zega, J.4
  • 22
    • 84889429974 scopus 로고    scopus 로고
    • Improving Liquid Distribution by Reducing Dimensionless Spray Flux in Wet Granulation-A Pharmaceutical Manufacturing Case Study.
    • 9th International Symposium on Agglomeration, Sheffield University, Sheffield, UK
    • Hapgood KP, Amelia R, Zaman MB, Merrett BK, Leslie P. Improving Liquid Distribution by Reducing Dimensionless Spray Flux in Wet Granulation-A Pharmaceutical Manufacturing Case Study. In: 9th International Symposium on Agglomeration, Sheffield University, Sheffield, UK, 2009.
    • (2009)
    • Hapgood, K.P.1    Amelia, R.2    Zaman, M.B.3    Merrett, B.K.4    Leslie, P.5
  • 25
    • 0033039331 scopus 로고    scopus 로고
    • Effects and control of humidity and particle mixing in fluid-bed granulation
    • Schaafsma SH, Kossen NWF, Mos MT, Blauw L, Hoffman AC. Effects and control of humidity and particle mixing in fluid-bed granulation. AIChE J. 1999;45(6):1202-1210.
    • (1999) AIChE J. , vol.45 , Issue.6 , pp. 1202-1210
    • Schaafsma, S.H.1    Kossen, N.W.F.2    Mos, M.T.3    Blauw, L.4    Hoffman, A.C.5
  • 27
    • 69249240298 scopus 로고    scopus 로고
    • Predicting nuclei size distributions in wet granulation using dimensionless spray flux
    • Hapgood KP, Tan MXL, Chow DWY. Predicting nuclei size distributions in wet granulation using dimensionless spray flux. Adv. Powder Technol. 2009; 20(4): p. 293-297.
    • (2009) Adv. Powder Technol. , vol.20 , Issue.4 , pp. 293-297
    • Hapgood, K.P.1    Tan, M.X.L.2    Chow, D.W.Y.3
  • 30
    • 33646822123 scopus 로고    scopus 로고
    • Scaling factors in granular flow: analysis of experimental and simulations results
    • Laurent BFC. Scaling factors in granular flow: analysis of experimental and simulations results. Chem. Eng. Sci. 2006;61(13):4138-4146.
    • (2006) Chem. Eng. Sci. , vol.61 , Issue.13 , pp. 4138-4146
    • Laurent, B.F.C.1
  • 32
    • 0034282075 scopus 로고    scopus 로고
    • Motion in a particle bed agitated by a single blade
    • Laurent BFC, Bridgwater J, Parker DJ. Motion in a particle bed agitated by a single blade. AIChE J. 2000; 46(9):1723-1734.
    • (2000) AIChE J. , vol.46 , Issue.9 , pp. 1723-1734
    • Laurent, B.F.C.1    Bridgwater, J.2    Parker, D.J.3
  • 33
    • 2342505853 scopus 로고    scopus 로고
    • Stress measurements in high-shear granulators using calibrated test particles: application to scale-up
    • Tardos GI, Hapgood KP, Ipadeola OO, Michaels JN. Stress measurements in high-shear granulators using calibrated test particles: application to scale-up. Powder Technol. 2004; 140(3):217-227.
    • (2004) Powder Technol. , vol.140 , Issue.3 , pp. 217-227
    • Tardos, G.I.1    Hapgood, K.P.2    Ipadeola, O.O.3    Michaels, J.N.4
  • 34
    • 84889361499 scopus 로고    scopus 로고
    • Application of Spray Flux in Scale-Up of High Shear Wet Granulation Processes.
    • AIChE Annual Meeting, AIChE, San Francisco
    • Hapgood K, Jain S, Kline L, Moaddeb M, Zega J. Application of Spray Flux in Scale-Up of High Shear Wet Granulation Processes. In: AIChE Annual Meeting, AIChE, San Francisco, 2003.
    • (2003)
    • Hapgood, K.1    Jain, S.2    Kline, L.3    Moaddeb, M.4    Zega, J.5
  • 35
    • 0037120736 scopus 로고    scopus 로고
    • The dynamic strength of partially saturated powder compacts: the effect of liquid properties
    • Iveson SM, Beathe JA, Page NW. The dynamic strength of partially saturated powder compacts: the effect of liquid properties. Powder Technol. 2002;127:149-161.
    • (2002) Powder Technol. , vol.127 , pp. 149-161
    • Iveson, S.M.1    Beathe, J.A.2    Page, N.W.3
  • 36
    • 84889317426 scopus 로고    scopus 로고
    • Dynamic mechanical properties of liquid bound powder compacts
    • 3rd Australasian Congress on Applied Mechanics (ACAM2002), Sydney, Australia: World Scientific
    • Iveson SM, Page N. Dynamic mechanical properties of liquid bound powder compacts, in 3rd Australasian Congress on Applied Mechanics (ACAM2002), Sydney, Australia: World Scientific, 2002.
    • (2002)
    • Iveson, S.M.1    Page, N.2
  • 37
    • 12344298544 scopus 로고    scopus 로고
    • Brittle to plastic transition in the dynamic mechanical behavior of partially saturated granular materials
    • Iveson SM, Page N. Brittle to plastic transition in the dynamic mechanical behavior of partially saturated granular materials. Trans. ASME 2004;71:470-475.
    • (2004) Trans. ASME , vol.71 , pp. 470-475
    • Iveson, S.M.1    Page, N.2
  • 38
    • 18344393977 scopus 로고    scopus 로고
    • Dynamic strength of liquid-bound granular materials: the effect of particle size and shape
    • Iveson SM, Page N. Dynamic strength of liquid-bound granular materials: the effect of particle size and shape. Powder Technol. 2005;152:79-89.
    • (2005) Powder Technol. , vol.152 , pp. 79-89
    • Iveson, S.M.1    Page, N.2
  • 42
    • 34248667556 scopus 로고    scopus 로고
    • Importance of evaluating the consolidation of granules manufactured by high shear mixer
    • Ohno I, Hasegawa S, Yada S, Kusai A, Moribe K, Yamamoto K. Importance of evaluating the consolidation of granules manufactured by high shear mixer. Int. J. Pharmaceut. 2007;338(1-2):79-86.
    • (2007) Int. J. Pharmaceut. , vol.338 , Issue.1-2 , pp. 79-86
    • Ohno, I.1    Hasegawa, S.2    Yada, S.3    Kusai, A.4    Moribe, K.5    Yamamoto, K.6
  • 43
    • 0037613447 scopus 로고    scopus 로고
    • Use of X-ray tomography to study the porosity and morphology of granules
    • Farber L, Tardos G, Michaels JN. Use of X-ray tomography to study the porosity and morphology of granules. Powder Technol. 2003;132(1):57-63.
    • (2003) Powder Technol. , vol.132 , Issue.1 , pp. 57-63
    • Farber, L.1    Tardos, G.2    Michaels, J.N.3
  • 44
    • 33747360211 scopus 로고    scopus 로고
    • Formation of hollow core granules by fluid bed in situ melt granulation: modelling and experiments
    • Ansari MA, Stepanek F. Formation of hollow core granules by fluid bed in situ melt granulation: modelling and experiments. Int. J. Pharmaceut. 2006;321(1-2):108-116.
    • (2006) Int. J. Pharmaceut. , vol.321 , Issue.1-2 , pp. 108-116
    • Ansari, M.A.1    Stepanek, F.2
  • 45
    • 33750567774 scopus 로고    scopus 로고
    • Design of granule structure: computational methods and experimental realization
    • Ansari MA, Stepanek F. Design of granule structure: computational methods and experimental realization. AIChE J. 2006;52(11):3762-3774.
    • (2006) AIChE J. , vol.52 , Issue.11 , pp. 3762-3774
    • Ansari, M.A.1    Stepanek, F.2
  • 46
    • 56949097040 scopus 로고    scopus 로고
    • Agglomeration of hydrophobic powders via solid spreading nucleation
    • Hapgood KP, Farber L, Michaels JN. Agglomeration of hydrophobic powders via solid spreading nucleation. Powder Technol. 2009;188(3):248-254.
    • (2009) Powder Technol. , vol.188 , Issue.3 , pp. 248-254
    • Hapgood, K.P.1    Farber, L.2    Michaels, J.N.3
  • 47
    • 62549138222 scopus 로고    scopus 로고
    • Characterisation of granule structure and strength made in a high shear granulator
    • Rahmanian N, Ghadiri M, Jia X, Stepanek F. Characterisation of granule structure and strength made in a high shear granulator. Powder Technol. 2009;192(2):184-194.
    • (2009) Powder Technol. , vol.192 , Issue.2 , pp. 184-194
    • Rahmanian, N.1    Ghadiri, M.2    Jia, X.3    Stepanek, F.4
  • 49
    • 0035807459 scopus 로고    scopus 로고
    • Effect of drying rate on porosity and tabletting behaviour of cellulose pellets
    • Berggren J, Alderborn G. Effect of drying rate on porosity and tabletting behaviour of cellulose pellets. Int. J. Pharmaceut. 2001;227:81-96.
    • (2001) Int. J. Pharmaceut. , vol.227 , pp. 81-96
    • Berggren, J.1    Alderborn, G.2
  • 50
    • 14644394898 scopus 로고    scopus 로고
    • Scale-up of binder agglomeration processes.
    • Mort PR. Scale-up of binder agglomeration processes. Powder Technol.150(2): 2005; 86-103.
    • (2005) Powder Technol , vol.150 , Issue.2 , pp. 86-103
    • Mort, P.R.1
  • 51
    • 2242441233 scopus 로고    scopus 로고
    • Fundamental Studies of Granulation: Granule Deformation and Consolidation
    • University of Queensland, Brisbane, Australia
    • Iveson SM. Fundamental Studies of Granulation: Granule Deformation and Consolidation, University of Queensland, Brisbane, Australia, 1997.
    • (1997)
    • Iveson, S.M.1
  • 52
    • 0032115497 scopus 로고    scopus 로고
    • Growth regime map for liquid-bound granules
    • Iveson SM, Litster JD. Growth regime map for liquid-bound granules. AIChE J. 1998;44(7):1510-1518.
    • (1998) AIChE J. , vol.44 , Issue.7 , pp. 1510-1518
    • Iveson, S.M.1    Litster, J.D.2
  • 55
    • 43049142992 scopus 로고    scopus 로고
    • The effect of powder size on induction behaviour and binder distribution during high shear melt agglomeration of calcium carbonate
    • TuW-D, Hsiau S-S, Ingram A, Seville J. The effect of powder size on induction behaviour and binder distribution during high shear melt agglomeration of calcium carbonate. Powder Technol. 2008;184(3):298-312.
    • (2008) Powder Technol. , vol.184 , Issue.3 , pp. 298-312
    • Tu, W.-D.1    Hsiau, S.-S.2    Ingram, A.3    Seville, J.4
  • 57
    • 0033962715 scopus 로고    scopus 로고
    • Effect of primary particle size on granule growth and endpoint determination in high-shear wet granulation
    • Mackaplow MB, Rosen LA, Michaels JN. Effect of primary particle size on granule growth and endpoint determination in high-shear wet granulation. Powder Technol. 2000; 108(1):32-45.
    • (2000) Powder Technol. , vol.108 , Issue.1 , pp. 32-45
    • Mackaplow, M.B.1    Rosen, L.A.2    Michaels, J.N.3
  • 58
    • 18644374182 scopus 로고    scopus 로고
    • The Science and Engineering and Granulation Processes
    • Kluwer Academic Publishers, Dordrecht
    • Litster JD, Ennis BJ. The Science and Engineering and Granulation Processes, Kluwer Academic Publishers, Dordrecht, 2004.
    • (2004)
    • Litster, J.D.1    Ennis, B.J.2
  • 59
    • 0025539875 scopus 로고
    • The influence of viscosity on the strength of an axially strained pendular liquid bridge
    • Ennis BJ, Li J, Tardos GI, Pfeffer R. The influence of viscosity on the strength of an axially strained pendular liquid bridge. Chem. Eng. Sci. 1990;45(10):3071-3088.
    • (1990) Chem. Eng. Sci. , vol.45 , Issue.10 , pp. 3071-3088
    • Ennis, B.J.1    Li, J.2    Tardos, G.I.3    Pfeffer, R.4
  • 60
    • 67649699185 scopus 로고    scopus 로고
    • Scale up considerations in granulation. In: Parikh DM, editor, Handbook of Pharmaceutical Granulation
    • Taylor and Francis Group, Boca Raton, FL
    • He Y, Liu LX, Litster JD, Kayrak-Talay D. Scale up considerations in granulation. In: Parikh DM, editor, Handbook of Pharmaceutical Granulation, Taylor and Francis Group, Boca Raton, FL, 2009, pp. 459-490.
    • (2009) , pp. 459-490
    • He, Y.1    Liu, L.X.2    Litster, J.D.3    Kayrak-Talay, D.4
  • 61
    • 0003323543 scopus 로고    scopus 로고
    • Size reduction and size enlargement.
    • Green D, editor, Perry's Chemical Engineers' Handbook, McGraw-Hill, New York
    • Ennis BJ, Litster JD. Size reduction and size enlargement., In: Green D, editor, Perry's Chemical Engineers' Handbook, McGraw-Hill, New York, 1997.
    • (1997)
    • Ennis, B.J.1    Litster, J.D.2
  • 64
    • 0342378046 scopus 로고    scopus 로고
    • Critical parameters and limiting conditions in binder granulation of fine powders
    • Tardos GI, Khan MI, Mort PR. Critical parameters and limiting conditions in binder granulation of fine powders. Powder Technol. 1997;94:245-258.
    • (1997) Powder Technol. , vol.94 , pp. 245-258
    • Tardos, G.I.1    Khan, M.I.2    Mort, P.R.3
  • 65
    • 61349178482 scopus 로고    scopus 로고
    • Wet Granule Breakage in High Shear Mixer Granulators
    • PhD Thesis, Department of Chemical Engineering, University of Queensland, Brisbane, Australia
    • Smith R. Wet Granule Breakage in High Shear Mixer Granulators, PhD Thesis, Department of Chemical Engineering, University of Queensland, Brisbane, Australia, 2008.
    • (2008)
    • Smith, R.1
  • 66
  • 67
    • 0037453852 scopus 로고    scopus 로고
    • The importance of wetpowder dynamic mechanical properties in understanding granulation
    • Iveson SM, Page NW, Litster JD. The importance of wetpowder dynamic mechanical properties in understanding granulation. Powder Technol. 2003;130:97-101.
    • (2003) Powder Technol. , vol.130 , pp. 97-101
    • Iveson, S.M.1    Page, N.W.2    Litster, J.D.3
  • 68
    • 0043124405 scopus 로고    scopus 로고
    • Granule breakage phenomena in a high shear mixer; influence of process and formulation variables and consequences on granule homogeneity
    • van den Dries K, Vegt OMd, Girard V, Vromans H. Granule breakage phenomena in a high shear mixer; influence of process and formulation variables and consequences on granule homogeneity. Powder Technol. 2003;113:228-236.
    • (2003) Powder Technol. , vol.113 , pp. 228-236
    • van den Dries, K.1    Vegt, O.M.D.2    Girard, V.3    Vromans, H.4
  • 69
    • 77957349470 scopus 로고    scopus 로고
    • Breakage of drop nucleated granules in a breakage only high shear mixer
    • doi 10.1016/j.ces.2010.06.037
    • Smith RM, Liu LX, Litster JD. Breakage of drop nucleated granules in a breakage only high shear mixer. Chem. Eng. Sci. 2010; doi:10.1016/j.ces.2010.06.037.
    • (2010) Chem. Eng. Sci.
    • Smith, R.M.1    Liu, L.X.2    Litster, J.D.3
  • 70
    • 58349106657 scopus 로고    scopus 로고
    • Wet granule breakage in a breakage only high-hear mixer: effect of formulation properties on breakage behaviour
    • Liu LX, Smith R, Litster JD. Wet granule breakage in a breakage only high-hear mixer: effect of formulation properties on breakage behaviour. Powder Technol. 2009; 189(2):158-164.
    • (2009) Powder Technol. , vol.189 , Issue.2 , pp. 158-164
    • Liu, L.X.1    Smith, R.2    Litster, J.D.3
  • 71
    • 0034640762 scopus 로고    scopus 로고
    • An investigation of the effects on agglomeration of changing the speed of a mechanical mixer
    • Knight PC, Johansen A, Kristensen HG, Schæfer T, Seville JPK. An investigation of the effects on agglomeration of changing the speed of a mechanical mixer. Powder Technol. 2000;110:204-209.
    • (2000) Powder Technol. , vol.110 , pp. 204-209
    • Knight, P.C.1    Johansen, A.2    Kristensen, H.G.3    Schæfer, T.4    Seville, J.P.K.5
  • 72
    • 0013059296 scopus 로고    scopus 로고
    • Tracer studies of high-shear granulation I: experimental results
    • Pearson JKM, Hounslow MJ, Instone T. Tracer studies of high-shear granulation I: experimental results. AIChE J. 2001;47(9):1978-1983.
    • (2001) AIChE J. , vol.47 , Issue.9 , pp. 1978-1983
    • Pearson, J.K.M.1    Hounslow, M.J.2    Instone, T.3
  • 73
    • 0344110493 scopus 로고    scopus 로고
    • Scaledown of a high shear pelletisation process: flow profile and growth kinetics
    • Ramaker JS, Jelgersma MA, Vonk P, Kossen NWF. Scaledown of a high shear pelletisation process: flow profile and growth kinetics. Int. J. Pharmaceut. 1998;166:89-97.
    • (1998) Int. J. Pharmaceut. , vol.166 , pp. 89-97
    • Ramaker, J.S.1    Jelgersma, M.A.2    Vonk, P.3    Kossen, N.W.F.4
  • 74
    • 0001011075 scopus 로고    scopus 로고
    • Tracer studies of high-shear granulation: II population balance modeling
    • Hounslow MJ, Pearson JMK, Instone T. Tracer studies of high-shear granulation: II population balance modeling. AIChE J. 2001;47(9):1984-1999.
    • (2001) AIChE J. , vol.47 , Issue.9 , pp. 1984-1999
    • Hounslow, M.J.1    Pearson, J.M.K.2    Instone, T.3
  • 75
    • 33745488845 scopus 로고    scopus 로고
    • The use of Stokes deformation number as a predictive tool for material exchange behaviour of granules in the ?equilibrium phase?
    • Bouwman AM, Visser MR, Meesters GMH, FrijlinkHW. The use of Stokes deformation number as a predictive tool for material exchange behaviour of granules in the ?equilibrium phase? in high shear granulation. Int. J. Pharmaceut. 2006; 318(1-2):78-85.
    • (2006) in high shear granulation. Int. J. Pharmaceut. , vol.318 , Issue.1-2 , pp. 78-85
    • Bouwman, A.M.1    Visser, M.R.2    Meesters, G.M.H.3    Frijlink, H.W.4
  • 76
    • 84889457137 scopus 로고    scopus 로고
    • Powder flow in mixer granulators.
    • Chemical Engineering, University of Queensland, Brisbane, Australia
    • Tran A. Powder flow in mixer granulators. In: Chemical Engineering, University of Queensland, Brisbane, Australia, 2010.
    • (2010)
    • Tran, A.1
  • 79
    • 0040279872 scopus 로고
    • Effect of impeller and chopper design on granulation in a high speed mixer
    • Holm P. Effect of impeller and chopper design on granulation in a high speed mixer. Drug Dev. Ind. Pharm. 1987; 13(9-11):1675-1701.
    • (1987) Drug Dev. Ind. Pharm. , vol.13 , Issue.9-11 , pp. 1675-1701
    • Holm, P.1
  • 80
    • 0033663970 scopus 로고    scopus 로고
    • Effects of interactions between powder particle size and binder viscosity on agglomerate growth mechanisms in a high shear mixer
    • Johansen A, Schæfer T. Effects of interactions between powder particle size and binder viscosity on agglomerate growth mechanisms in a high shear mixer. Eur. J. Pharmaceut. Sci. 2001;12:297-309.
    • (2001) Eur. J. Pharmaceut. Sci. , vol.12 , pp. 297-309
    • Johansen, A.1    Schæfer, T.2
  • 82
    • 0011733758 scopus 로고
    • The factors affecting fluidised bed granulation
    • Aulton M, Banks M. The factors affecting fluidised bed granulation. Manuf. Chemist Aer. N. 1978;49:50-56.
    • (1978) Manuf. Chemist Aer. N. , vol.49 , pp. 50-56
    • Aulton, M.1    Banks, M.2
  • 83
    • 0004205647 scopus 로고
    • Particle Size Enlargement
    • Elsevier Scientific Publishing Company, Amsterdam
    • Capes CE. Particle Size Enlargement, Elsevier Scientific Publishing Company, Amsterdam, 1980.
    • (1980)
    • Capes, C.E.1
  • 84
    • 0037452433 scopus 로고    scopus 로고
    • Scaling up of the fluidized bed granulation process
    • Rambali B, Baert L, Massart DL. Scaling up of the fluidized bed granulation process. Int. J. Pharmaceut. 2003;252:197-206.
    • (2003) Int. J. Pharmaceut. , vol.252 , pp. 197-206
    • Rambali, B.1    Baert, L.2    Massart, D.L.3
  • 85
    • 84889321060 scopus 로고    scopus 로고
    • Use of Dimensionless Spray Flux to Scale Up aWet Granulated Product
    • World Congress on Particle Technology 4, Sydney, Australia
    • Hapgood K, Plank R, Zega J. Use of Dimensionless Spray Flux to Scale Up aWet Granulated Product. In: World Congress on Particle Technology 4, Sydney, Australia, 2002.
    • (2002)
    • Hapgood, K.1    Plank, R.2    Zega, J.3
  • 86
    • 0035828741 scopus 로고    scopus 로고
    • Simulated and measured flow of granules in a bladed mixer-a detailed comparison
    • Stewart RL, Bridgwater J, Zhou YC, Yu AB. Simulated and measured flow of granules in a bladed mixer-a detailed comparison. Chem. Eng. Sci. 2001;56:5457-5471.
    • (2001) Chem. Eng. Sci. , vol.56 , pp. 5457-5471
    • Stewart, R.L.1    Bridgwater, J.2    Zhou, Y.C.3    Yu, A.B.4
  • 87
    • 0037118273 scopus 로고    scopus 로고
    • Performance of single and six-bladed powder mixers
    • Laurent BFC, Bridgwater J. Performance of single and six-bladed powder mixers. Chem. Eng. Sci. 2002;57: 1695-1709.
    • (2002) Chem. Eng. Sci. , vol.57 , pp. 1695-1709
    • Laurent, B.F.C.1    Bridgwater, J.2
  • 89
    • 39049156707 scopus 로고    scopus 로고
    • Direct measurement of surface granular temperature in a high shear granulator
    • Reynolds GK, Nilpawar AM, Salman AD, Hounslow MJ. Direct measurement of surface granular temperature in a high shear granulator. Powder Technol. 2008;182(2):211-217.
    • (2008) Powder Technol. , vol.182 , Issue.2 , pp. 211-217
    • Reynolds, G.K.1    Nilpawar, A.M.2    Salman, A.D.3    Hounslow, M.J.4
  • 90
    • 84889316362 scopus 로고    scopus 로고
    • Positron Emission Particle Tracking Studies of Powder Mixing in a Planetary Mixer.
    • Control of Particulate Processes IV, Engineering Foundation, Delft, Netherlands
    • Hiseman MJP, Bridgwater J, Wilson DI. Positron Emission Particle Tracking Studies of Powder Mixing in a Planetary Mixer. In: Control of Particulate Processes IV, Engineering Foundation, Delft, Netherlands, 1997.
    • (1997)
    • Hiseman, M.J.P.1    Bridgwater, J.2    Wilson, D.I.3
  • 92
    • 84889480073 scopus 로고    scopus 로고
    • Scale-Up of Mixer Granulators for Effective Liquid Distribution.
    • Control of Particulate Processes 6, Engineering Foundation, Fraser Island, Australia
    • Litster JD, Hapgood KP, Michaels JN, Kamineni SK, Sims A, Roberts M, Hsu T. Scale-Up of Mixer Granulators for Effective Liquid Distribution. In: Control of Particulate Processes 6, Engineering Foundation, Fraser Island, Australia, 1999.
    • (1999)
    • Litster, J.D.1    Hapgood, K.P.2    Michaels, J.N.3    Kamineni, S.K.4    Sims, A.5    Roberts, M.6    Hsu, T.7
  • 93
    • 37549045980 scopus 로고    scopus 로고
    • Effect of scale of operation on granule strength in high shear granulators
    • Rahmanian N, Ghadiri M, Ding Y. Effect of scale of operation on granule strength in high shear granulators. Chem. Eng. Sci. 2008;63(4):915-923.
    • (2008) Chem. Eng. Sci. , vol.63 , Issue.4 , pp. 915-923
    • Rahmanian, N.1    Ghadiri, M.2    Ding, Y.3
  • 96
    • 36249009562 scopus 로고    scopus 로고
    • Modeling of agglomerate behavior under shear deformation: effect of velocity field of a high shear mixer granulator on the structure of agglomerates
    • Hassanpour A, Antony SJ, Ghadiri M. Modeling of agglomerate behavior under shear deformation: effect of velocity field of a high shear mixer granulator on the structure of agglomerates. Adv. Powder Technol. 2007;18:803-811.
    • (2007) Adv. Powder Technol. , vol.18 , pp. 803-811
    • Hassanpour, A.1    Antony, S.J.2    Ghadiri, M.3
  • 97
    • 84889353643 scopus 로고    scopus 로고
    • Characterisation of impact stress from main impeller on granules during granulation processes in a high shear mixer
    • Salman AD, editor, 9th International Symposium on Agglomeration, Sheffield University, Sheffield, UK
    • Fu J, Chan EL, Jones MR, Kemp IC, Gilmour CM, Hounslow MJ, Salman AD. Characterisation of impact stress from main impeller on granules during granulation processes in a high shear mixer. In: Salman AD, editor, 9th International Symposium on Agglomeration, Sheffield University, Sheffield, UK, 2009.
    • (2009)
    • Fu, J.1    Chan, E.L.2    Jones, M.R.3    Kemp, I.C.4    Gilmour, C.M.5    Hounslow, M.J.6    Salman, A.D.7
  • 98
    • 58349095167 scopus 로고    scopus 로고
    • Scale-up and control of binder agglomeration processes-flow and stress fields
    • Mort PR. Scale-up and control of binder agglomeration processes-flow and stress fields. Powder Technol. 2009;189(2):313-317.
    • (2009) Powder Technol. , vol.189 , Issue.2 , pp. 313-317
    • Mort, P.R.1
  • 99
    • 0032920861 scopus 로고    scopus 로고
    • Applicability of a scale-up method for wet granulation processes in Collette Gral high shear mixer-granulators
    • Faure A, Grimsey IM, Rowe RC, York P, Cliff MJ. Applicability of a scale-up method for wet granulation processes in Collette Gral high shear mixer-granulators. Eur. J. Pharmaceut. Sci. 1999;8:85-93.
    • (1999) Eur. J. Pharmaceut. Sci. , vol.8 , pp. 85-93
    • Faure, A.1    Grimsey, I.M.2    Rowe, R.C.3    York, P.4    Cliff, M.J.5
  • 100
    • 84889381085 scopus 로고    scopus 로고
    • Determination of the Coalescence Probability ofWet Granules by Mesoscale Modeling
    • AIChE Annual Meeting, AIChE, San Francisco, CA
    • Stepanek F, Rajniak P, Mancinelli C, Chern R, Determination of the Coalescence Probability ofWet Granules by Mesoscale Modeling. In: AIChE Annual Meeting, AIChE, San Francisco, CA, 2006.
    • (2006)
    • Stepanek, F.1    Rajniak, P.2    Mancinelli, C.3    Chern, R.4
  • 101
    • 58349117900 scopus 로고    scopus 로고
    • A narrow size distribution on a high shear mixer by applying a flux number approach
    • Boerefijn R, Juvin PY, Garzon P. A narrow size distribution on a high shear mixer by applying a flux number approach. Powder Technol. 2009;189(2):172-176.
    • (2009) Powder Technol. , vol.189 , Issue.2 , pp. 172-176
    • Boerefijn, R.1    Juvin, P.Y.2    Garzon, P.3
  • 102
    • 58349112120 scopus 로고    scopus 로고
    • Granulation of hydrophobic powders
    • Hapgood KP, Khanmohammadi B. Granulation of hydrophobic powders. Powder Technol. 2009;189(2):253-262.
    • (2009) Powder Technol. , vol.189 , Issue.2 , pp. 253-262
    • Hapgood, K.P.1    Khanmohammadi, B.2
  • 103
    • 18644363185 scopus 로고    scopus 로고
    • Continuous granulation in the pharmaceutical industry
    • Vervaet C, Remon JP. Continuous granulation in the pharmaceutical industry. Chem. Eng. Sci. 2005;60(14):3949-3957.
    • (2005) Chem. Eng. Sci. , vol.60 , Issue.14 , pp. 3949-3957
    • Vervaet, C.1    Remon, J.P.2
  • 104
    • 55749091428 scopus 로고    scopus 로고
    • Impact of screw elements on continuous granulation with a twin-screw extruder
    • Djuric D, Kleinebudde P. Impact of screw elements on continuous granulation with a twin-screw extruder. J. Pharmaceut. Sci. 2009;97(11):4934-4942.
    • (2009) J. Pharmaceut. Sci. , vol.97 , Issue.11 , pp. 4934-4942
    • Djuric, D.1    Kleinebudde, P.2
  • 105
    • 36549008702 scopus 로고    scopus 로고
    • Study growth kinetics in fluidized bed granulation with at-line FBRM
    • Hu X, Cunningham JC,Winstead D. Study growth kinetics in fluidized bed granulation with at-line FBRM. Int. J. Pharmaceut. 2008;347(1-2):54-61.
    • (2008) Int. J. Pharmaceut. , vol.347 , Issue.1-2 , pp. 54-61
    • Hu, X.1    Cunningham, J.C.2    Winstead, D.3
  • 106
    • 67649447344 scopus 로고    scopus 로고
    • Evaluation of the physical and mechanical properties of high drug load formulations: wet granulation vs
    • Cantor SL, Kothari S, Koo OMY. Evaluation of the physical and mechanical properties of high drug load formulations: wet granulation vs. novel foam granulation. Powder Technol. 2009;195(1):15-24.
    • (2009) novel foam granulation. Powder Technol. , vol.195 , Issue.1 , pp. 15-24
    • Cantor, S.L.1    Kothari, S.2    Koo, O.M.Y.3
  • 107
    • 5444256444 scopus 로고    scopus 로고
    • Preliminary report of the discovery of a new pharmaceutical granulation process using foamed aqueous binders
    • Keary CM, Sheskey PJ. Preliminary report of the discovery of a new pharmaceutical granulation process using foamed aqueous binders. Drug Dev. Ind. Pharm. 2004;30(8):831-845.
    • (2004) Drug Dev. Ind. Pharm. , vol.30 , Issue.8 , pp. 831-845
    • Keary, C.M.1    Sheskey, P.J.2
  • 108
    • 67349272010 scopus 로고    scopus 로고
    • Foam and drop penetration kinetics into loosely packed powder beds.
    • Tan MXL, Wong LS, Lum KH, Hapgood KP. Foam and drop penetration kinetics into loosely packed powder beds. Chem. Eng. Sci. 2009;64(12):2826-2836.
    • (2009) Chem. Eng. Sci , vol.64 , Issue.12 , pp. 2826-2836
    • Tan, M.X.L.1    Wong, L.S.2    Lum, K.H.3    Hapgood, K.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.