Effect of primary particle size on granule growth and endpoint determination in high-shear wet granulation

Powder Technology

Volumn 108, Issue 1, 2000, Pages 32-45

  MacKaplow, Michael B ^a   Rosen, Lawrence A ^a   Michaels, James N ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Agglomeration; Granulation; Mixers; Particle size; Power curves

Indexed keywords

AGGLOMERATION; CHAOS THEORY; CORRELATION METHODS; MIXERS (MACHINERY); PARTICLE SIZE ANALYSIS; POROSITY; POROUS MATERIALS; SATURATION (MATERIALS COMPOSITION); TORQUE; WATER;

LACTOSE MONOHYDRATE;

GRANULATION;

LACTOSE;

GRANULAR SOLID; PARTICLE SIZE;

ARTICLE; DRUG GRANULATION; PARTICLE SIZE; POWDER; SHEAR RATE; TORQUE;

EID: 0033962715     PISSN: 00325910     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0032-5910(99)00203-X     Document Type: Article

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