Mechanistic understanding of gene delivery mediated by highly efficient multicomponent envelope-type nanoparticle systems

Molecular Pharmaceutics

Volumn 10, Issue 12, 2013, Pages 4654-4665

  Pozzi, D ^a   Marchini, C ^b   Cardarelli, F ^c   Rossetta, A ^a   Colapicchioni, V ^a,d   Amici, A ^b   Montani, M ^b   Motta, S ^e   Brocca, P ^e   Cantu L ^e   Caracciolo, G ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b UNIVERSITY OF CAMERINO   (Italy)

^c CENTER FOR NANOTECHNOLOGY INNOVATION NEST   (Italy)

^d ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

^e UNIVERSITY OF MILAN   (Italy)

Author keywords

endosomal escape; gene delivery; nanoparticles; transfection

Indexed keywords

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; DIOLEOYLPHOSPHATIDYLETHANOLAMINE; LIPOSOME; MICROSPHERE; NANOCARRIER; NANOMATERIAL; NANOPARTICLE; PROTAMINE;

ACTIVE TRANSPORT; ANIMAL CELL; ARTICLE; ATOMIC FORCE MICROSCOPY; CELL VIABILITY; CHO CELL; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOSOL; DNA DEGRADATION; DRUG FORMULATION; ENDOCYTOSIS; ENDOSOME; FEMALE; FLOW CYTOMETRY; GENE TARGETING; HYDRODYNAMICS; LIGHT SCATTERING; LIPID BILAYER; LIPID VESICLE; LIPOSOMAL DELIVERY; LYSOSOME; MICROELECTROPHORESIS; MICROTUBULE; MULTICOMPONENT ENVELOPE NANOPARTICLE SYSTEM; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PARTICLE SIZE; PINOCYTOSIS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SPECTROSCOPY; SYNCHROTRON; X RAY CRYSTALLOGRAPHY; ZETA POTENTIAL;

ANIMALS; CHO CELLS; CHOLESTEROL; CRICETULUS; DNA; ENDOCYTOSIS; ENDOSOMES; FATTY ACIDS, MONOUNSATURATED; GENE TRANSFER TECHNIQUES; LIPIDS; LIPOSOMES; NANOPARTICLES; PHOSPHATIDYLCHOLINES; PHOSPHATIDYLETHANOLAMINES; PROTAMINES; QUATERNARY AMMONIUM COMPOUNDS; TRANSFECTION;

EID: 84889260209     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp400470p     Document Type: Article

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