High gene delivery in tumor by intratumoral injection of tetraarginine-PEG lipid-coated protamine/DNA

Journal of Controlled Release

Volumn 129, Issue 2, 2008, Pages 124-127

  Fujita, Takashi ^a   Furuhata, Masahiko ^a   Hattori, Yoshiyuki ^a   Kawakami, Hiroko ^b   Toma, Kazunori ^b   Maitani, Yoshie ^a  

^a HOSHI UNIVERSITY   (Japan)

^b NOGUCHI INSTITUTE   (Japan)

Author keywords

DNA delivery; In vivo transfection; Intratumor injection; Oligoarginine; Protamine

Indexed keywords

COATINGS; DNA; GENETIC ENGINEERING; LIPIDS; SYNTHESIS (CHEMICAL);

DNA DELIVERY; INTRATUMOR INJECTION; OLIGOARGININE; PROTAMINE;

POLYETHYLENE GLYCOLS;

ARGININE DERIVATIVE; DNA PROTAMINE COMPLEX; OLIGOARGININE PLUS 3,5 BIS(DODECYLOXY)BENZAMIDE LIPID PLUS MACROGOL CONJUGATE; PEPTIDES AND PROTEINS;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; FEMALE; GENE TARGETING; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO GENE TRANSFER; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NONVIRAL GENE THERAPY; PRIORITY JOURNAL; UTERINE CERVIX CARCINOMA; XENOGRAFT;

ANIMALS; ARGININE; DNA; FEMALE; GENE THERAPY; HELA CELLS; HUMANS; INJECTIONS, INTRALESIONAL; LIPIDS; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASMS; OLIGOPEPTIDES; PARTICLE SIZE; POLYETHYLENE GLYCOLS; PROTAMINES; TRANSFECTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 46549083593     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2008.04.010     Document Type: Article

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