-
1
-
-
77950362382
-
The inflammasomes
-
Epub 2010/03/23
-
Schroder K, Tschopp J. The inflammasomes. Cell. 2010;140:821-832. Epub 2010/03/23.
-
(2010)
Cell
, vol.140
, pp. 821-832
-
-
Schroder, K.1
Tschopp, J.2
-
2
-
-
0036671894
-
The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
-
Epub 2002/08/23
-
Martinon F, Burns K, Tschopp J. The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol Cell. 2002;10:417-426. Epub 2002/08/23.
-
(2002)
Mol Cell
, vol.10
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
3
-
-
70249138036
-
Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression
-
Epub 2009/07/03
-
Bauernfeind FG, Horvath G, Stutz A, et al. Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression. J Immunol. 2009;183:787-791. Epub 2009/07/03.
-
(2009)
J Immunol
, vol.183
, pp. 787-791
-
-
Bauernfeind, F.G.1
Horvath, G.2
Stutz, A.3
-
4
-
-
47849085872
-
The NALP3 inflammasome is involved in the innate immune response to amyloid-beta
-
Epub 2008/07/08
-
Halle A, Hornung V, Petzold GC, et al. The NALP3 inflammasome is involved in the innate immune response to amyloid-beta. Nat Immunol. 2008;9:857-865. Epub 2008/07/08.
-
(2008)
Nat Immunol
, vol.9
, pp. 857-865
-
-
Halle, A.1
Hornung, V.2
Petzold, G.C.3
-
5
-
-
77951800951
-
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
-
Epub 2010/04/30
-
Duewell P, Kono H, Rayner KJ, et al. NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. Nature. 2010;464:1357-1361. Epub 2010/04/30.
-
(2010)
Nature
, vol.464
, pp. 1357-1361
-
-
Duewell, P.1
Kono, H.2
Rayner, K.J.3
-
6
-
-
80052164574
-
The inflammasome: An integrated view
-
Epub 2011/09/03
-
Gross O, Thomas CJ, Guarda G, et al. The inflammasome: An integrated view. Immunol Rev. 2011;243:136-151. Epub 2011/09/03.
-
(2011)
Immunol Rev
, vol.243
, pp. 136-151
-
-
Gross, O.1
Thomas, C.J.2
Guarda, G.3
-
7
-
-
34047174085
-
A pilot study of IL-1 inhibition by anakinra in acute gout
-
So A, de Smedt T, Revaz S, et al. A pilot study of IL-1 inhibition by anakinra in acute gout. Arthritis Res Ther. 2007;9(2):R28.
-
(2007)
Arthritis Res Ther
, vol.9
, Issue.2
-
-
So, A.1
De Smedt, T.2
Revaz, S.3
-
8
-
-
79953677480
-
Efficacy and safety of anakinra therapy in pediatric and adult patients with the autoinflammatory Muckle-Wells syndrome
-
Kuemmerle-Deschner JB, Tyrrell PN, Koetter I, et al. Efficacy and safety of anakinra therapy in pediatric and adult patients with the autoinflammatory Muckle-Wells syndrome. Arthritis Rheum. 2011; 63(3):840-849.
-
(2011)
Arthritis Rheum
, vol.63
, Issue.3
, pp. 840-849
-
-
Kuemmerle-Deschner, J.B.1
Tyrrell, P.N.2
Koetter, I.3
-
9
-
-
79952053673
-
Canakinumab (ACZ885, a fully human IgG1 anti-IL-1beta mAb) induces sustained remission in pediatric patients with cryopyrin-associated periodic syndrome (CAPS)
-
Kuemmerle-Deschner JB, Ramos E, Blank N, et al. Canakinumab (ACZ885, a fully human IgG1 anti-IL-1beta mAb) induces sustained remission in pediatric patients with cryopyrin-associated periodic syndrome (CAPS). Arthritis Res Ther. 2011;13(1):R34.
-
(2011)
Arthritis Res Ther
, vol.13
, Issue.1
-
-
Kuemmerle-Deschner, J.B.1
Ramos, E.2
Blank, N.3
-
10
-
-
32944468985
-
Gout-associated uric acid crystals activate the NALP3 inflammasome
-
Martinon F, Petrilli V, Mayor A, et al. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature. 2006;440(7081):237-241.
-
(2006)
Nature
, vol.440
, Issue.7081
, pp. 237-241
-
-
Martinon, F.1
Petrilli, V.2
Mayor, A.3
-
11
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Epub 2011/03/08
-
Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;144:646-674. Epub 2011/03/08.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
12
-
-
54549089856
-
Overexpression of interleukin-1beta induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice
-
Epub 2008/11/04
-
Tu S, Bhagat G, Cui G, et al. Overexpression of interleukin-1beta induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice. Cancer Cell. 2008;14:408-419. Epub 2008/11/04.
-
(2008)
Cancer Cell
, vol.14
, pp. 408-419
-
-
Tu, S.1
Bhagat, G.2
Cui, G.3
-
13
-
-
68349102201
-
Interleukin-1beta and fibroblast growth factor receptor 1 cooperate to induce cyclooxygenase-2 during early mammary tumourigenesis
-
Epub 2009/04/28
-
Reed JR, Leon RP, Hall MK, et al. Interleukin-1beta and fibroblast growth factor receptor 1 cooperate to induce cyclooxygenase-2 during early mammary tumourigenesis. Breast Cancer Res. 2009;11:R21. Epub 2009/04/28.
-
(2009)
Breast Cancer Res
, vol.11
-
-
Reed, J.R.1
Leon, R.P.2
Hall, M.K.3
-
14
-
-
33847060965
-
Interleukin-1betaYdriven inflammation promotes the development and invasiveness of chemical carcinogen-induced tumors
-
Epub 2007/02/07
-
Krelin Y, Voronov E, Dotan S, et al. Interleukin-1betaYdriven inflammation promotes the development and invasiveness of chemical carcinogen-induced tumors. Cancer Res. 2007;67:1062-1071. Epub 2007/02/07.
-
(2007)
Cancer Res
, vol.67
, pp. 1062-1071
-
-
Krelin, Y.1
Voronov, E.2
Dotan, S.3
-
15
-
-
78649610261
-
IL-1beta regulates a novel myeloid-derived suppressor cell subset that impairs NK cell development and function
-
Epub 2010/11/27
-
Elkabets M, Ribeiro VS, Dinarello CA, et al. IL-1beta regulates a novel myeloid-derived suppressor cell subset that impairs NK cell development and function. Eur J Immunol. 2010;40:3347-3357. Epub 2010/11/27.
-
(2010)
Eur J Immunol
, vol.40
, pp. 3347-3357
-
-
Elkabets, M.1
Ribeiro, V.S.2
Dinarello, C.A.3
-
16
-
-
84868615556
-
IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine
-
Epub 2012/10/19
-
Huber S, Gagliani N, Zenewicz LA, et al. IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine. Nature. 2012;491:259-263. Epub 2012/10/19.
-
(2012)
Nature
, vol.491
, pp. 259-263
-
-
Huber, S.1
Gagliani, N.2
Zenewicz, L.A.3
-
17
-
-
77955350419
-
MyD88-mediated signaling prevents development of adenocarcinomas of the colon: Role of interleukin
-
Epub 2010/07/14
-
Salcedo R, Worschech A, Cardone M, et al. MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin J Exp Med. 2010;207:1625-1636. Epub 2010/07/14.
-
(2010)
J Exp Med
, vol.207
, pp. 1625-1636
-
-
Salcedo, R.1
Worschech, A.2
Cardone, M.3
-
18
-
-
77949965210
-
Control of intestinal homeostasis, colitis, and colitis-associated colorectal cancer by the inflammatory caspases
-
Dupaul-Chicoine J, Yeretssian G, Doiron K, et al. Control of intestinal homeostasis, colitis, and colitis-associated colorectal cancer by the inflammatory caspases. Immunity. 2010;32(3):367-378.
-
(2010)
Immunity
, vol.32
, Issue.3
, pp. 367-378
-
-
Dupaul-Chicoine, J.1
Yeretssian, G.2
Doiron, K.3
-
19
-
-
78049488908
-
IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation
-
Epub 2010/09/22
-
Zaki MH, Vogel P, Body-Malapel M, et al. IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation. J Immunol. 2010;185:4912-4920. Epub 2010/09/22.
-
(2010)
J Immunol
, vol.185
, pp. 4912-4920
-
-
Zaki, M.H.1
Vogel, P.2
Body-Malapel, M.3
-
20
-
-
0033152023
-
IL-18, a novel immunoregulatory cytokine, is up-regulated in Crohn's disease: Expression and localization in intestinal mucosal cells
-
Pizarro TT, Michie MH, Bentz M, et al. IL-18, a novel immunoregulatory cytokine, is up-regulated in Crohn's disease: expression and localization in intestinal mucosal cells. J Immunol. 1999;162(11):6829-6835.
-
(1999)
J Immunol
, vol.162
, Issue.11
, pp. 6829-6835
-
-
Pizarro, T.T.1
Michie, M.H.2
Bentz, M.3
-
21
-
-
77952303410
-
The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer
-
Epub 2010/04/14
-
Allen IC, TeKippe EM, Woodford RM, et al. The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer. J Exp Med. 2010;207:1045-1056. Epub 2010/04/14.
-
(2010)
J Exp Med
, vol.207
, pp. 1045-1056
-
-
Allen, I.C.1
Tekippe, E.M.2
Woodford, R.M.3
-
22
-
-
78650735879
-
Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4
-
Epub 2010/12/02
-
Hu B, Elinav E, Huber S, et al. Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4. Proc Natl Acad Sci U S A. 2010;107:21635-21640. Epub 2010/12/02.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 21635-21640
-
-
Hu, B.1
Elinav, E.2
Huber, S.3
-
23
-
-
79957576718
-
NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis
-
Epub 2011/05/14
-
Elinav E, Strowig T, Kau AL, et al. NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis. Cell. 2011;145:745-757. Epub 2011/05/14.
-
(2011)
Cell
, vol.145
, pp. 745-757
-
-
Elinav, E.1
Strowig, T.2
Kau, A.L.3
-
24
-
-
84863469984
-
Interleukin-1, inflammasomes, autoinflammation and the skin
-
Epub 2012/06/02
-
Contassot E, Beer HD, French LE. Interleukin-1, inflammasomes, autoinflammation and the skin. Swiss Med Wkly. 2012;142:w13590. Epub 2012/06/02.
-
(2012)
Swiss Med Wkly
, vol.142
-
-
Contassot, E.1
Beer, H.D.2
French, L.E.3
-
25
-
-
34250835251
-
The inflammasome mediates UVB-induced activation and secretion of interleukin-1beta by keratinocytes
-
Epub 2007/06/30
-
Feldmeyer L, Keller M, Niklaus G, et al. The inflammasome mediates UVB-induced activation and secretion of interleukin-1beta by keratinocytes. Curr Biol. 2007;17:1140-1145. Epub 2007/06/30.
-
(2007)
Curr Biol
, vol.17
, pp. 1140-1145
-
-
Feldmeyer, L.1
Keller, M.2
Niklaus, G.3
-
26
-
-
84870551811
-
NLRP3 promotes inflammationinduced skin cancer but is dispensable for asbestos-induced mesothelioma
-
Epub 2012/09/27
-
Chow MT, Tschopp J, Moller A, et al. NLRP3 promotes inflammationinduced skin cancer but is dispensable for asbestos-induced mesothelioma. Immunol Cell Biol. 2012;90:983-986. Epub 2012/09/27.
-
(2012)
Immunol Cell Biol
, vol.90
, pp. 983-986
-
-
Chow, M.T.1
Tschopp, J.2
Moller, A.3
-
27
-
-
84868529740
-
Tissue-specific opposing functions of the inflammasome adaptor ASC in the regulation of epithelial skin carcinogenesis
-
Epub 2012/10/24
-
Drexler SK, Bonsignore L, Masin M, et al. Tissue-specific opposing functions of the inflammasome adaptor ASC in the regulation of epithelial skin carcinogenesis. Proc Natl Acad Sci U S A. 2012;109: 18384-18389. Epub 2012/10/24.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 18384-18389
-
-
Drexler, S.K.1
Bonsignore, L.2
Masin, M.3
-
28
-
-
77949889567
-
Constitutively active inflammasome in human melanoma cells mediating autoinflammation via caspase-1 processing and secretion of interleukin-1beta
-
Epub 2009/12/30
-
Okamoto M, Liu W, Luo Y, et al. Constitutively active inflammasome in human melanoma cells mediating autoinflammation via caspase-1 processing and secretion of interleukin-1beta. J Biol Chem. 2010;285: 6477-6488. Epub 2009/12/30.
-
(2010)
J Biol Chem
, vol.285
, pp. 6477-6488
-
-
Okamoto, M.1
Liu, W.2
Luo, Y.3
-
29
-
-
84872607356
-
Dual role of apoptosis-associated specklike protein containing a CARD (ASC) in tumorigenesis of human melanoma
-
Epub 2012/08/31
-
Liu W, Luo Y, Dunn JH, et al. Dual role of apoptosis-associated specklike protein containing a CARD (ASC) in tumorigenesis of human melanoma. J Invest Dermatol. 2013;133:518-527. Epub 2012/08/31.
-
(2013)
J Invest Dermatol
, vol.133
, pp. 518-527
-
-
Liu, W.1
Luo, Y.2
Dunn, J.H.3
-
30
-
-
0035179970
-
Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome
-
Epub 2001/11/01
-
Hoffman HM, Mueller JL, Broide DH, et al. Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. Nat Genet. 2001;29:301-305. Epub 2001/11/01.
-
(2001)
Nat Genet
, vol.29
, pp. 301-305
-
-
Hoffman, H.M.1
Mueller, J.L.2
Broide, D.H.3
-
31
-
-
77953122347
-
Evidence of interaction of CARD8 rs2043211 with NALP3 rs35829419 in Crohn's disease
-
Epub 2010/02/26
-
Roberts RL, Topless RK, Phipps-Green AJ, et al. Evidence of interaction of CARD8 rs2043211 with NALP3 rs35829419 in Crohn's disease. Genes Immun. 2010;11:351-356. Epub 2010/02/26.
-
(2010)
Genes Immun
, vol.11
, pp. 351-356
-
-
Roberts, R.L.1
Topless, R.K.2
Phipps-Green, A.J.3
-
32
-
-
43049159804
-
Genetic variation in proteins of the cryopyrin inflammasome influences susceptibility and severity of rheumatoid arthritis (the Swedish TIRA project)
-
Epub 2008/02/12
-
Kastbom A, Verma D, Eriksson P, et al. Genetic variation in proteins of the cryopyrin inflammasome influences susceptibility and severity of rheumatoid arthritis (the Swedish TIRA project). Rheumatology (Oxford). 2008;47:415-417. Epub 2008/02/12.
-
(2008)
Rheumatology (Oxford)
, vol.47
, pp. 415-417
-
-
Kastbom, A.1
Verma, D.2
Eriksson, P.3
-
33
-
-
84862646126
-
Inflammasome polymorphisms confer susceptibility to sporadic malignant melanoma
-
Epub 2012/04/25
-
Verma D, Bivik C, Farahani E, et al. Inflammasome polymorphisms confer susceptibility to sporadic malignant melanoma. Pigment Cell Melanoma Res. 2012;25:506-513. Epub 2012/04/25.
-
(2012)
Pigment Cell Melanoma Res
, vol.25
, pp. 506-513
-
-
Verma, D.1
Bivik, C.2
Farahani, E.3
-
34
-
-
84868626486
-
Genetic variation and alterations of genes involved in NFkappaB/TNFAIP3-and NLRP3-inflammasome signaling affect susceptibility and outcome of colorectal cancer
-
Epub 2012/07/31
-
Ungerback J, Belenki D, Jawad ul-Hassan A, et al. Genetic variation and alterations of genes involved in NFkappaB/TNFAIP3-and NLRP3-inflammasome signaling affect susceptibility and outcome of colorectal cancer. Carcinogenesis. 2012;33:2126-2134. Epub 2012/07/31.
-
(2012)
Carcinogenesis
, vol.33
, pp. 2126-2134
-
-
Ungerback, J.1
Belenki, D.2
Jawad Ul-Hassan, A.3
-
35
-
-
43249125839
-
Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
-
Epub 2008/04/12
-
Dostert C, Petrilli V, van Bruggen R, et al. Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science. 2008;320:674-677. Epub 2008/04/12.
-
(2008)
Science
, vol.320
, pp. 674-677
-
-
Dostert, C.1
Petrilli, V.2
Van Bruggen, R.3
-
36
-
-
85040956314
-
NLRP1 polymorphisms in patients with asbestos-associated mesothelioma
-
Epub 2012/10/04
-
Girardelli M, Maestri I, Rinaldi RR, et al. NLRP1 polymorphisms in patients with asbestos-associated mesothelioma. Infect Agent Cancer. 2012;7:25. Epub 2012/10/04.
-
(2012)
Infect Agent Cancer
, vol.7
, pp. 25
-
-
Girardelli, M.1
Maestri, I.2
Rinaldi, R.R.3
-
37
-
-
75649096002
-
Thioredoxin-interacting protein links oxidative stress to inflammasome activation
-
Epub 2009/12/22
-
Zhou R, Tardivel A, Thorens B, et al. Thioredoxin-interacting protein links oxidative stress to inflammasome activation. Nat Immunol. 2010; 11:136-140. Epub 2009/12/22.
-
(2010)
Nat Immunol
, vol.11
, pp. 136-140
-
-
Zhou, R.1
Tardivel, A.2
Thorens, B.3
-
38
-
-
77956958947
-
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1beta in type 2 diabetes
-
Epub 2010/09/14
-
Masters SL, Dunne A, Subramanian SL, et al. Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1beta in type 2 diabetes. Nat Immunol. 2010;11:897-904. Epub 2010/09/14.
-
(2010)
Nat Immunol
, vol.11
, pp. 897-904
-
-
Masters, S.L.1
Dunne, A.2
Subramanian, S.L.3
-
39
-
-
79751512463
-
The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
-
Epub 2011/01/11
-
Vandanmagsar B, Youm YH, Ravussin A, et al. The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance. Nat Med. 2011;17:179-188. Epub 2011/01/11.
-
(2011)
Nat Med
, vol.17
, pp. 179-188
-
-
Vandanmagsar, B.1
Youm, Y.H.2
Ravussin, A.3
-
41
-
-
70449727077
-
Glyburide inhibits the cryopyrin/Nalp3 inflammasome
-
Epub 2009/10/07
-
LamkanfiM,Mueller JL, Vitari AC, et al. Glyburide inhibits the cryopyrin/Nalp3 inflammasome. J Cell Biol. 2009;187:61-70. Epub 2009/10/07.
-
(2009)
J Cell Biol
, vol.187
, pp. 61-70
-
-
Lamkanfimmueller, J.L.1
Vitari, A.C.2
-
42
-
-
79956196320
-
Reactive oxygen species (ROS)Yinduced genetic and epigenetic alterations in human carcinogenesis
-
Epub 2011/03/23
-
Ziech D, Franco R, Pappa A, et al. Reactive oxygen species (ROS)Yinduced genetic and epigenetic alterations in human carcinogenesis. Mutat Res. 2011;711:167-173. Epub 2011/03/23.
-
(2011)
Mutat Res
, vol.711
, pp. 167-173
-
-
Ziech, D.1
Franco, R.2
Pappa, A.3
-
43
-
-
84876285741
-
Succinate is an inflammatory signal that induces IL-1beta through HIF-1alpha
-
Epub 2013/03/29
-
Tannahill GM, Curtis AM, Adamik J, et al. Succinate is an inflammatory signal that induces IL-1beta through HIF-1alpha. Nature. 2013;496:238-242. Epub 2013/03/29.
-
(2013)
Nature
, vol.496
, pp. 238-242
-
-
Tannahill, G.M.1
Curtis, A.M.2
Adamik, J.3
-
44
-
-
70449105185
-
Macrophage-derived IL-1beta stimulates Wnt signaling and growth of colon cancer cells: A crosstalk interrupted by vitamin D3
-
Epub 2009/08/25
-
Kaler P, Augenlicht L, Klampfer L. Macrophage-derived IL-1beta stimulates Wnt signaling and growth of colon cancer cells: A crosstalk interrupted by vitamin D3. Oncogene. 2009;28:3892-3902. Epub 2009/08/25.
-
(2009)
Oncogene
, vol.28
, pp. 3892-3902
-
-
Kaler, P.1
Augenlicht, L.2
Klampfer, L.3
-
45
-
-
48649109203
-
Hepatocyte necrosis induced by oxidative stress and IL-1 alpha release mediate carcinogen-induced compensatory proliferation and liver tumorigenesis
-
Epub 2008/08/12
-
Sakurai T, He G, Matsuzawa A, et al. Hepatocyte necrosis induced by oxidative stress and IL-1 alpha release mediate carcinogen-induced compensatory proliferation and liver tumorigenesis. Cancer Cell. 2008;14:156-165. Epub 2008/08/12.
-
(2008)
Cancer Cell
, vol.14
, pp. 156-165
-
-
Sakurai, T.1
He, G.2
Matsuzawa, A.3
-
46
-
-
0037418208
-
IL-1 is required for tumor invasiveness and angiogenesis
-
Epub 2003/02/25
-
Voronov E, Shouval DS, Krelin Y, et al. IL-1 is required for tumor invasiveness and angiogenesis. Proc Natl Acad Sci U S A. 2003;100: 2645-2650. Epub 2003/02/25.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 2645-2650
-
-
Voronov, E.1
Shouval, D.S.2
Krelin, Y.3
-
47
-
-
33846018602
-
Cell death by necrosis: Towards a molecular definition
-
Epub 2006/12/05
-
Golstein P, Kroemer G. Cell death by necrosis: towards a molecular definition. Trends Biochem Sci. 2007;32:37-43. Epub 2006/12/05.
-
(2007)
Trends Biochem Sci
, vol.32
, pp. 37-43
-
-
Golstein, P.1
Kroemer, G.2
-
48
-
-
0029738195
-
A bacterial invasin induces macrophage apoptosis by binding directly to ICE
-
Epub 1996/08/01
-
Chen Y, Smith MR, Thirumalai K, et al. A bacterial invasin induces macrophage apoptosis by binding directly to ICE. EMBO J. 1996;15: 3853-3860. Epub 1996/08/01.
-
(1996)
EMBO J
, vol.15
, pp. 3853-3860
-
-
Chen, Y.1
Smith, M.R.2
Thirumalai, K.3
-
49
-
-
34548031870
-
The pyroptosome: A supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation
-
Epub 2007/06/30
-
Fernandes-Alnemri T, Wu J, Yu JW, et al. The pyroptosome: A supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation. Cell Death Differ. 2007;14:1590-1604. Epub 2007/06/30.
-
(2007)
Cell Death Differ
, vol.14
, pp. 1590-1604
-
-
Fernandes-Alnemri, T.1
Wu, J.2
Yu, J.W.3
-
50
-
-
0028943734
-
Apoptosis in the pathogenesis and treatment of disease
-
Epub 1995/03/10
-
Thompson CB. Apoptosis in the pathogenesis and treatment of disease. Science. 1995;267:1456-1462. Epub 1995/03/10.
-
(1995)
Science
, vol.267
, pp. 1456-1462
-
-
Thompson, C.B.1
-
51
-
-
0035117041
-
Loss of caspase-1 and caspase-3 protein expression in human prostate cancer
-
Epub 2001/02/28
-
Winter RN, Kramer A, Borkowski A, et al. Loss of caspase-1 and caspase-3 protein expression in human prostate cancer. Cancer Res. 2001;61:1227-1232. Epub 2001/02/28.
-
(2001)
Cancer Res
, vol.61
, pp. 1227-1232
-
-
Winter, R.N.1
Kramer, A.2
Borkowski, A.3
-
52
-
-
3242674432
-
Caspase-1 enhances the apoptotic response of prostate cancer cells to ionizing radiation
-
Epub 2004/07/28
-
Winter RN, Rhee JG, Kyprianou N. Caspase-1 enhances the apoptotic response of prostate cancer cells to ionizing radiation. Anticancer Res. 2004;24:1377-1386. Epub 2004/07/28.
-
(2004)
Anticancer Res
, vol.24
, pp. 1377-1386
-
-
Winter, R.N.1
Rhee, J.G.2
Kyprianou, N.3
-
53
-
-
79952390627
-
Immune parameters affecting the efficacy of chemotherapeutic regimens
-
Zitvogel L, Kepp O, Kroemer G. Immune parameters affecting the efficacy of chemotherapeutic regimens. Nat Rev Clin Oncol. 2011;8(3): 151-160.
-
(2011)
Nat Rev Clin Oncol
, vol.8
, Issue.3
, pp. 151-160
-
-
Zitvogel, L.1
Kepp, O.2
Kroemer, G.3
-
54
-
-
70350569295
-
Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors
-
Epub 2009/09/22
-
Ghiringhelli F, Apetoh L, Tesniere A, et al. Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors. Nat Med. 2009;15:1170-1178. Epub 2009/09/22.
-
(2009)
Nat Med
, vol.15
, pp. 1170-1178
-
-
Ghiringhelli, F.1
Apetoh, L.2
Tesniere, A.3
-
55
-
-
76249128304
-
Tumor cell death and ATP release prime dendritic cells and efficient anticancer immunity
-
Epub 2010/01/21
-
Aymeric L, Apetoh L, Ghiringhelli F, et al. Tumor cell death and ATP release prime dendritic cells and efficient anticancer immunity. Cancer Res. 2010;70:855-858. Epub 2010/01/21.
-
(2010)
Cancer Res
, vol.70
, pp. 855-858
-
-
Aymeric, L.1
Apetoh, L.2
Ghiringhelli, F.3
-
56
-
-
84872086179
-
Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth
-
Epub 2012/12/04
-
Bruchard M, Mignot G, Derangere V, et al. Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth. Nat Med. 2013;19: 57-64. Epub 2012/12/04.
-
(2013)
Nat Med
, vol.19
, pp. 57-64
-
-
Bruchard, M.1
Mignot, G.2
Derangere, V.3
-
57
-
-
78650360196
-
The inflammasome component NLRP3 impairs antitumor vaccine by enhancing the accumulation of tumor-associated myeloid-derived suppressor cells
-
Epub 2010/12/17
-
van Deventer HW, Burgents JE, Wu QP, et al. The inflammasome component NLRP3 impairs antitumor vaccine by enhancing the accumulation of tumor-associated myeloid-derived suppressor cells. Cancer Res. 2010;70:10161-10169. Epub 2010/12/17.
-
(2010)
Cancer Res
, vol.70
, pp. 10161-10169
-
-
Van Deventer, H.W.1
Burgents, J.E.2
Wu, Q.P.3
-
58
-
-
79960605654
-
B regulatory cells and the tumor-promoting actions of TNF-alpha during squamous carcinogenesis
-
Schioppa T, Moore R, Thompson RG, et al. B regulatory cells and the tumor-promoting actions of TNF-alpha during squamous carcinogenesis. Proc Natl Acad Sci U S A. 2011;108(26):10662-10667.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, Issue.26
, pp. 10662-10667
-
-
Schioppa, T.1
Moore, R.2
Thompson, R.G.3
-
59
-
-
84874192617
-
T-helper-1-cell cytokines drive cancer into senescence
-
Epub 2013/02/05
-
Braumuller H, Wieder T, Brenner E, et al. T-helper-1-cell cytokines drive cancer into senescence. Nature. 2013;494:361-365. Epub 2013/02/05.
-
(2013)
Nature
, vol.494
, pp. 361-365
-
-
Braumuller, H.1
Wieder, T.2
Brenner, E.3
|