-
1
-
-
0034611791
-
Obesity as a medical problem
-
Kopelman P. G., Obesity as a medical problem. Nature 2000 404 6778 635 643 2-s2.0-0034611791 (Pubitemid 30205068)
-
(2000)
Nature
, vol.404
, Issue.6778
, pp. 635-643
-
-
Kopelman, P.G.1
-
2
-
-
81355164063
-
Obesity: Overview of an epidemic
-
2-s2.0-81355164063 10.1016/j.psc.2011.08.005
-
Mitchell N. S., Catenacci V. A., Wyatt H. R., Hill J. O., Obesity: overview of an epidemic. Psychiatric Clinics of North America 2011 34 4 717 732 2-s2.0-81355164063 10.1016/j.psc.2011.08.005
-
(2011)
Psychiatric Clinics of North America
, vol.34
, Issue.4
, pp. 717-732
-
-
Mitchell, N.S.1
Catenacci, V.A.2
Wyatt, H.R.3
Hill, J.O.4
-
3
-
-
84875642011
-
Physical activity in obesity and metabolic syndrome
-
10.1111/j.1749-6632.2012.06785.x
-
Strasser B., Physical activity in obesity and metabolic syndrome. Annals of the New York Academy of Sciences 2013 1281 141 159 10.1111/j.1749-6632.2012. 06785.x
-
(2013)
Annals of the New York Academy of Sciences
, vol.1281
, pp. 141-159
-
-
Strasser, B.1
-
4
-
-
34548449306
-
Role of myokines in exercise and metabolism
-
DOI 10.1152/japplphysiol.00080.2007
-
Pedersen B. K., Åkerström T. C. A., Nielsen A. R., Fischer C. P., Role of myokines in exercise and metabolism. Journal of Applied Physiology 2007 103 3 1093 1098 2-s2.0-34548449306 10.1152/japplphysiol.00080.2007 (Pubitemid 47358897)
-
(2007)
Journal of Applied Physiology
, vol.103
, Issue.3
, pp. 1093-1098
-
-
Pedersen, B.K.1
Akerstrom, T.C.A.2
Nielsen, A.R.3
Fischer, C.P.4
-
5
-
-
84864283300
-
Muscles, exercise and obesity: Skeletal muscle as a secretory organ
-
2-s2.0-84859095015 10.1038/nrendo.2012.49
-
Pedersen B. K., Febbraio M. A., Muscles, exercise and obesity: skeletal muscle as a secretory organ. Nature Reviews Endocrinology 2012 8 457 465 2-s2.0-84859095015 10.1038/nrendo.2012.49
-
(2012)
Nature Reviews Endocrinology
, vol.8
, pp. 457-465
-
-
Pedersen, B.K.1
Febbraio, M.A.2
-
6
-
-
64349105205
-
Identification and importance of brown adipose tissue in adult humans
-
2-s2.0-64349105205 10.1056/NEJMoa0810780
-
Cypess A. M., Lehman S., Williams G., Tal I., Rodman D., Goldfine A. B., Kuo F. C., Palmer E. L., Tseng Y., Doria A., Kolodny G. M., Kahn C. R., Identification and importance of brown adipose tissue in adult humans. New England Journal of Medicine 2009 360 15 1509 1517 2-s2.0-64349105205 10.1056/NEJMoa0810780
-
(2009)
New England Journal of Medicine
, vol.360
, Issue.15
, pp. 1509-1517
-
-
Cypess, A.M.1
Lehman, S.2
Williams, G.3
Tal, I.4
Rodman, D.5
Goldfine, A.B.6
Kuo, F.C.7
Palmer, E.L.8
Tseng, Y.9
Doria, A.10
Kolodny, G.M.11
Kahn, C.R.12
-
8
-
-
64349095231
-
Cold-activated brown adipose tissue in healthy men
-
2-s2.0-64349095231 10.1056/NEJMoa0808718
-
van Marken Lichtenbelt W. D., Vanhommerig J. W., Smulders N. M., Drossaerts J. M. A. F. L., Kemerink G. J., Bouvy N. D., Schrauwen P., Teule G. J. J., Cold-activated brown adipose tissue in healthy men. New England Journal of Medicine 2009 360 15 1500 1508 2-s2.0-64349095231 10.1056/NEJMoa0808718
-
(2009)
New England Journal of Medicine
, vol.360
, Issue.15
, pp. 1500-1508
-
-
Van Marken Lichtenbelt, W.D.1
Vanhommerig, J.W.2
Smulders, N.M.3
Drossaerts, J.M.A.F.L.4
Kemerink, G.J.5
Bouvy, N.D.6
Schrauwen, P.7
Teule, G.J.J.8
-
9
-
-
64349123664
-
Functional brown adipose tissue in healthy adults
-
2-s2.0-64349123664 10.1056/NEJMoa0808949
-
Virtanen K. A., Lidell M. E., Orava J., Heglind M., Westergren R., Niemi T., Taittonen M., Laine J., Savisto N., Enerbäck S., Nuutila P., Functional brown adipose tissue in healthy adults. New England Journal of Medicine 2009 360 15 1518 1525 2-s2.0-64349123664 10.1056/NEJMoa0808949
-
(2009)
New England Journal of Medicine
, vol.360
, Issue.15
, pp. 1518-1525
-
-
Virtanen, K.A.1
Lidell, M.E.2
Orava, J.3
Heglind, M.4
Westergren, R.5
Niemi, T.6
Taittonen, M.7
Laine, J.8
Savisto, N.9
Enerbäck, S.10
Nuutila, P.11
-
10
-
-
0347989317
-
Brown Adipose Tissue: Function and Physiological Significance
-
DOI 10.1152/physrev.00015.2003
-
Cannon B., Nedergaard J., Brown adipose tissue: function and physiological significance. Physiological Reviews 2004 84 1 277 359 2-s2.0-0347989317 10.1152/physrev.00015.2003 (Pubitemid 38054374)
-
(2004)
Physiological Reviews
, vol.84
, Issue.1
, pp. 277-359
-
-
Cannon, B.1
Nedergaard, J.2
-
11
-
-
0032549811
-
A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
-
DOI 10.1016/S0092-8674(00)81410-5
-
Puigserver P., Wu Z., Park C. W., Graves R., Wright M., Spiegelman B. M., A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell 1998 92 6 829 839 2-s2.0-0032549811 10.1016/S0092-8674(00) 81410-5 (Pubitemid 28155321)
-
(1998)
Cell
, vol.92
, Issue.6
, pp. 829-839
-
-
Puigserver, P.1
Wu, Z.2
Park, C.W.3
Graves, R.4
Wright, M.5
Spiegelman, B.M.6
-
12
-
-
33646124709
-
Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation
-
2-s2.0-33646124709 10.1016/j.cmet.2006.04.002
-
Uldry M., Yang W., St-Pierre J., Lin J., Seale P., Spiegelman B. M., Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation. Cell Metabolism 2006 3 5 333 341 2-s2.0-33646124709 10.1016/j.cmet.2006.04.002
-
(2006)
Cell Metabolism
, vol.3
, Issue.5
, pp. 333-341
-
-
Uldry, M.1
Yang, W.2
St-Pierre, J.3
Lin, J.4
Seale, P.5
Spiegelman, B.M.6
-
13
-
-
0036866036
-
Mitochondrial biogenesis in brown adipose tissue is associated with differential expression of transcription regulatory factors
-
DOI 10.1007/PL00012516
-
Villena J. A., Carmona M. C., Rodriguez de la Concepción M., Rossmeisl M., Viñas O., Mampel T., Iglesias R., Giralt M., Villarroya F., Mitochondrial biogenesis in brown adipose tissue is associated with differential expression of transcription regulatory factors. Cellular and Molecular Life Sciences 2002 59 11 1934 1944 2-s2.0-0036866036 10.1007/PL00012516 (Pubitemid 36015866)
-
(2002)
Cellular and Molecular Life Sciences
, vol.59
, Issue.11
, pp. 1934-1944
-
-
Villena, J.A.1
Carmona, M.C.2
Rodriguez De La Concepcion, M.3
Rossmeisl, M.4
Vinas, O.5
Mampel, T.6
Iglesias, R.7
Giralt, M.8
Villarroya, F.9
-
14
-
-
0033538473
-
Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1
-
DOI 10.1016/S0092-8674(00)80611-X
-
Wu Z., Puigserver P., Andersson U., Zhang C., Adelmant G., Mootha V., Troy A., Cinti S., Lowell B., Scarpulla R. C., Spiegelman B. M., Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. Cell 1999 98 1 115 124 2-s2.0-0033538473 10.1016/S0092- 8674(00)80611-X (Pubitemid 29331201)
-
(1999)
Cell
, vol.98
, Issue.1
, pp. 115-124
-
-
Wu, Z.1
Puigserver, P.2
Andersson, U.3
Zhang, C.4
Adelmant, G.5
Mootha, V.6
Troy, A.7
Cinti, S.8
Lowell, B.9
Scarpulla, R.C.10
Spiegelman, B.M.11
-
15
-
-
0036903174
-
Adaptations of skeletal muscle to exercise: Rapid increase in the transcriptional coactivator PGC-1
-
DOI 10.1096/fj.02-0367com
-
Baar K., Wende A. R., Jones T. E., Marison M., Nolte L. A., Chen M., Kelly D. P., Holloszy J. O., Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1. FASEB Journal 2002 16 14 1879 1886 2-s2.0-0036903174 10.1096/fj.02-0367com (Pubitemid 35462607)
-
(2002)
FASEB Journal
, vol.16
, Issue.14
, pp. 1879-1886
-
-
Baar, K.1
Wende, A.R.2
Jones, T.E.3
Marison, M.4
Nolte, L.A.5
Chen, M.6
Kelly, D.P.7
Holloszy, J.O.8
-
16
-
-
0037322888
-
Exercise induces transient transcriptional activation of the PGC-1α gene in human skeletal muscle
-
DOI 10.1113/jphysiol.2002.034850
-
Pilegaard H., Saltin B., Neufer D. P., Exercise induces transient transcriptional activation of the PGC-1 α gene in human skeletal muscle. Journal of Physiology 2003 546 3 851 858 2-s2.0-0037322888 10.1113/jphysiol. 2002.034850 (Pubitemid 36204518)
-
(2003)
Journal of Physiology
, vol.546
, Issue.3
, pp. 851-858
-
-
Pilegaard, H.1
Saltin, B.2
Neufer, D.P.3
-
17
-
-
34547545892
-
AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α
-
DOI 10.1073/pnas.0705070104
-
Jäer S., Handschin C., St-Pierre J., Spiegelman B. M., AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1 α Proceedings of the National Academy of Sciences of the United States of America 2007 104 29 12017 12022 2-s2.0-34547545892 10.1073/pnas.0705070104 (Pubitemid 47185622)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.29
, pp. 12017-12022
-
-
Jaer, S.1
Handschin, C.2
St-Pierre, J.3
Spiegelman, B.M.4
-
18
-
-
10744228606
-
Endurance Training in Humans Leads to Fiber Type-Specific Increases in Levels of Peroxisome Proliferator-Activated Receptor-γ Coactivator-1 and Peroxisome Proliferator-Activated Receptor-α in Skeletal Muscle
-
DOI 10.2337/diabetes.52.12.2874
-
Russell A. P., Feilchenfeldt J., Schreiber S., Praz M., Crettenand A., Gobelet C., Meier C. A., Bell D. R., Kralli A., Giacobino J., Dériaz O., Endurance training in humans leads to fiber type-specific increases in levels of peroxisome proliferator-activated receptor- γ coactivator-1 and peroxisome proliferator-activated receptor- α in skeletal muscle. Diabetes 2003 52 12 2874 2881 2-s2.0-10744228606 10.2337/diabetes.52.12.2874 (Pubitemid 37466855)
-
(2003)
Diabetes
, vol.52
, Issue.12
, pp. 2874-2881
-
-
Russell, A.P.1
Feilchenfeldt, J.2
Schreiber, S.3
Praz, M.4
Crettenand, A.5
Gobelet, C.6
Meier, C.A.7
Bell, D.R.8
Kralli, A.9
Giacobino, J.-P.10
Deriaz, O.11
-
19
-
-
73949099327
-
Increased muscle PGC-1 α expression protects from sarcopenia and metabolic disease during aging
-
2-s2.0-73949099327 10.1073/pnas.0911570106
-
Wenz T., Rossi S. G., Rotundo R. L., Spiegelman B. M., Moraes C. T., Increased muscle PGC-1 α expression protects from sarcopenia and metabolic disease during aging. Proceedings of the National Academy of Sciences of the United States of America 2009 106 48 20405 20410 2-s2.0-73949099327 10.1073/pnas.0911570106
-
(2009)
Proceedings of the National Academy of Sciences of the United States of America
, vol.106
, Issue.48
, pp. 20405-20410
-
-
Wenz, T.1
Rossi, S.G.2
Rotundo, R.L.3
Spiegelman, B.M.4
Moraes, C.T.5
-
20
-
-
84862776702
-
A PGC1- α -dependent myokine that drives brown-fat-like development of white fat and thermogenesis
-
2-s2.0-84856218208 10.1038/nature10777
-
Boström P., Wu J., Jedrychowski M. P., Korde A., Ye L., Lo J. C., Rasbach K. A., Boström E. A., Choi J. H., Long J. Z., Kajimura S., Zingaretti M. C., Vind B. F., Tu H., Cinti S., Højlund K., Gygi S. P., Spiegelman B. M., A PGC1- α -dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature 2012 481 7382 463 468 2-s2.0-84856218208 10.1038/nature10777
-
(2012)
Nature
, vol.481
, Issue.7382
, pp. 463-468
-
-
Boström, P.1
Wu, J.2
Jedrychowski, M.P.3
Korde, A.4
Ye, L.5
Lo, J.C.6
Rasbach, K.A.7
Boström, E.A.8
Choi, J.H.9
Long, J.Z.10
Kajimura, S.11
Zingaretti, M.C.12
Vind, B.F.13
Tu, H.14
Cinti, S.15
Højlund, K.16
Gygi, S.P.17
Spiegelman, B.M.18
-
21
-
-
79955755051
-
Exercise ameliorates high-fat diet-induced metabolic and vascular dysfunction, and increases adipocyte progenitor cell population in brown adipose tissue
-
2-s2.0-79955755051 10.1152/ajpregu.00806.2010
-
Xu X., Ying Z., Cai M., Xu Z., Li Y., Jiang S. Y., Tzan K., Wang A., Parthasarathy S., He G., Rajagopalan S., Sun Q., Exercise ameliorates high-fat diet-induced metabolic and vascular dysfunction, and increases adipocyte progenitor cell population in brown adipose tissue. American Journal of Physiology 2011 300 5 R1115 R1125 2-s2.0-79955755051 10.1152/ajpregu.00806.2010
-
(2011)
American Journal of Physiology
, vol.300
, Issue.5
-
-
Xu, X.1
Ying, Z.2
Cai, M.3
Xu, Z.4
Li, Y.5
Jiang, S.Y.6
Tzan, K.7
Wang, A.8
Parthasarathy, S.9
He, G.10
Rajagopalan, S.11
Sun, Q.12
-
22
-
-
0035988932
-
Mouse PeP: A novel peroxisomal protein linked to myoblast differentiation and development
-
DOI 10.1002/dvdy.10099
-
Ferrer-Martínez A., Ruiz-Lozano P., Chien K. R., Mouse PeP: a novel peroxisomal protein linked to myoblast differentiation and development. Developmental Dynamics 2002 224 2 154 167 2-s2.0-0035988932 10.1002/dvdy.10099 (Pubitemid 34569057)
-
(2002)
Developmental Dynamics
, vol.224
, Issue.2
, pp. 154-167
-
-
Ferrer-Martinez, A.1
Ruiz-Lozano, P.2
Chien, K.R.3
-
23
-
-
0037019815
-
Frcp1 and Frcp2, two novel fibronectin type III repeat containing genes
-
DOI 10.1016/S0378-1119(02)00828-4, PII S0378111902008284
-
Teufel A., Malik N., Mukhopadhyay M., Westphal H., Frcp1 and Frcp2, two novel fibronectin type III repeat containing genes. Gene 2002 297 1-2 79 83 2-s2.0-0037019815 10.1016/S0378-1119(02)00828-4 (Pubitemid 35217782)
-
(2002)
Gene
, vol.297
, Issue.1-2
, pp. 79-83
-
-
Teufel, A.1
Malik, N.2
Mukhopadhyay, M.3
Westphal, H.4
-
24
-
-
84888386052
-
Irisin and FNDC5 in retrospect: An exercise hormone or a transmembrane receptor?
-
10.4161/adip.26082
-
Erickson H. P., Irisin and FNDC5 in retrospect: an exercise hormone or a transmembrane receptor? Adipocyte 2013 2 289 293 10.4161/adip.26082
-
(2013)
Adipocyte
, vol.2
, pp. 289-293
-
-
Erickson, H.P.1
-
25
-
-
84876133911
-
FNDC5/irisin is not only a myokine but also an adipokine
-
Roca-Rivada A., Castelao C., Senin L. L., Landrove M. O., Baltar J., Belen C. A., Seoane L. M., Casanueva F. F., Pardo M., FNDC5/irisin is not only a myokine but also an adipokine. PLoS One 2013 8 e60563
-
(2013)
PLoS One
, vol.8
-
-
Roca-Rivada, A.1
Castelao, C.2
Senin, L.L.3
Landrove, M.O.4
Baltar, J.5
Belen, C.A.6
Seoane, L.M.7
Casanueva, F.F.8
Pardo, M.9
-
26
-
-
84878240625
-
Banting lecture 2012: Regulation of adipogenesis: Toward new therapeutics for metabolic disease
-
10.2337/db12-1665
-
Spiegelman B. M., Banting lecture 2012: regulation of adipogenesis: toward new therapeutics for metabolic disease. Diabetes 2013 62 6 1774 1782 10.2337/db12-1665
-
(2013)
Diabetes
, vol.62
, Issue.6
, pp. 1774-1782
-
-
Spiegelman, B.M.1
-
27
-
-
84881016307
-
Muscle-to-organ cross talk mediated by myokines
-
10.4161/adip.20344
-
Pedersen L., Hojman P., Muscle-to-organ cross talk mediated by myokines. Adipocyte 2012 1 3 164 167 10.4161/adip.20344
-
(2012)
Adipocyte
, vol.1
, Issue.3
, pp. 164-167
-
-
Pedersen, L.1
Hojman, P.2
-
28
-
-
84879295847
-
Adipo-myokines: Two sides of the same coin - Mediators of inflammation and mediators of exercise
-
320724 10.1155/2013/320724
-
Raschke S., Eckel J., Adipo-myokines: two sides of the same coin-mediators of inflammation and mediators of exercise. Mediators of Inflammation 2013 2013 16 320724 10.1155/2013/320724
-
(2013)
Mediators of Inflammation
, vol.2013
, pp. 16
-
-
Raschke, S.1
Eckel, J.2
-
29
-
-
79958767884
-
Myostatin: A novel insight into its role in metabolism, signal pathways, and expression regulation
-
2-s2.0-79958767884 10.1016/j.cellsig.2011.05.003
-
Huang Z., Chen X., Chen D., Myostatin: a novel insight into its role in metabolism, signal pathways, and expression regulation. Cellular Signalling 2011 23 9 1441 1446 2-s2.0-79958767884 10.1016/j.cellsig.2011.05.003
-
(2011)
Cellular Signalling
, vol.23
, Issue.9
, pp. 1441-1446
-
-
Huang, Z.1
Chen, X.2
Chen, D.3
-
30
-
-
84877147751
-
Myostatin knockout drives browning of white adipose tissue through activating the AMPK-PGC1alpha-Fndc5 pathway in muscle
-
10.1096/fj.12-225755
-
Shan T., Liang X., Bi P., Kuang S., Myostatin knockout drives browning of white adipose tissue through activating the AMPK-PGC1alpha-Fndc5 pathway in muscle. The FASEB Journal 2013 27 5 1981 1989 10.1096/fj.12-225755
-
(2013)
The FASEB Journal
, vol.27
, Issue.5
, pp. 1981-1989
-
-
Shan, T.1
Liang, X.2
Bi, P.3
Kuang, S.4
-
31
-
-
84867346134
-
Greater insulin sensitivity in calorie restricted rats occurs with unaltered circulating levels of several important myokines and cytokines
-
10.1186/1743-7075-9-90
-
Sharma N., Castorena C. M., Cartee G. D., Greater insulin sensitivity in calorie restricted rats occurs with unaltered circulating levels of several important myokines and cytokines. Nutrition & Metabolism 2012 9 90 10.1186/1743-7075-9-90
-
(2012)
Nutrition & Metabolism
, vol.9
, pp. 90
-
-
Sharma, N.1
Castorena, C.M.2
Cartee, G.D.3
-
32
-
-
84881296709
-
Free fatty acid effects on myokine production in combination with exercise mimetics
-
10.1002/mnfr.201300126
-
Sanchez J., Nozhenko Y., Palou A., Rodriguez A. M., Free fatty acid effects on myokine production in combination with exercise mimetics. Molecular Nutrition & Food Research 2013 57 8 1456 1467 10.1002/mnfr.201300126
-
(2013)
Molecular Nutrition & Food Research
, vol.57
, Issue.8
, pp. 1456-1467
-
-
Sanchez, J.1
Nozhenko, Y.2
Palou, A.3
Rodriguez, A.M.4
-
33
-
-
84867899565
-
Conjugated linoleic acid or omega 3 fatty acids increase mitochondrial biosynthesis and metabolism in skeletal muscle cells
-
10.1186/1476-511X-11-142
-
Vaughan R. A., Garcia-Smith R., Bisoffi M., Conn C. A., Trujillo K. A., Conjugated linoleic acid or omega 3 fatty acids increase mitochondrial biosynthesis and metabolism in skeletal muscle cells. Lipids in Health and Disease 2012 11 142 10.1186/1476-511X-11-142
-
(2012)
Lipids in Health and Disease
, vol.11
, pp. 142
-
-
Vaughan, R.A.1
Garcia-Smith, R.2
Bisoffi, M.3
Conn, C.A.4
Trujillo, K.A.5
-
34
-
-
84863229962
-
Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes
-
10.1172/JCI59701
-
Bordicchia M., Liu D., Amri E., Ailhaud G., Dessì-Fulgheri P., Zhang C., Takahashi N., Sarzani R., Collins S., Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes. Journal of Clinical Investigation 2012 122 3 1022 1036 10.1172/JCI59701
-
(2012)
Journal of Clinical Investigation
, vol.122
, Issue.3
, pp. 1022-1036
-
-
Bordicchia, M.1
Liu, D.2
Amri, E.3
Ailhaud, G.4
Dessì-Fulgheri, P.5
Zhang, C.6
Takahashi, N.7
Sarzani, R.8
Collins, S.9
-
35
-
-
84859507081
-
Medicine: Irisin, light my fire
-
2-s2.0-84859507081 10.1126/science.1221688
-
Kelly D. P., Medicine: Irisin, light my fire. Science 2012 335 6077 42 43 2-s2.0-84859507081 10.1126/science.1221688
-
(2012)
Science
, vol.335
, Issue.6077
, pp. 42-43
-
-
Kelly, D.P.1
-
36
-
-
84857855831
-
NPs-heart hormones that regulate brown fat?
-
2-s2.0-84857855831 10.1172/JCI62595
-
Whittle A. J., Vidal-Puig A., NPs-heart hormones that regulate brown fat? Journal of Clinical Investigation 2012 122 3 804 807 2-s2.0-84857855831 10.1172/JCI62595
-
(2012)
Journal of Clinical Investigation
, vol.122
, Issue.3
, pp. 804-807
-
-
Whittle, A.J.1
Vidal-Puig, A.2
-
37
-
-
84880573265
-
Elevated skeletal muscle irisin precursor FNDC5 mRNA in obese OLETF rats
-
10.1016/j.metabol.2013.02.002
-
Roberts M. D., Bayless D. S., Company J. M., Jenkins N. T., Padilla J., Childs T. E., Martin J. S., Dalbo V. J., Booth F. W., Rector R. S., Laughlin M. H., Elevated skeletal muscle irisin precursor FNDC5 mRNA in obese OLETF rats. Metabolism 2013 62 8 1052 1056 10.1016/j.metabol.2013.02.002
-
(2013)
Metabolism
, vol.62
, Issue.8
, pp. 1052-1056
-
-
Roberts, M.D.1
Bayless, D.S.2
Company, J.M.3
Jenkins, N.T.4
Padilla, J.5
Childs, T.E.6
Martin, J.S.7
Dalbo, V.J.8
Booth, F.W.9
Rector, R.S.10
Laughlin, M.H.11
-
38
-
-
84878656502
-
Leptin's role in lipodystrophic and nonlipodystrophic insulin-resistant and diabetic individuals
-
10.1210/er.2012-1053
-
Moon H. S., Dalamaga M., Kim S. Y., Polyzos S. A., Hamnvik O. P., Magkos F., Paruthi J., Mantzoros C. S., Leptin's role in lipodystrophic and nonlipodystrophic insulin-resistant and diabetic individuals. Endocrine Reviews 2013 34 3 377 412 10.1210/er.2012-1053
-
(2013)
Endocrine Reviews
, vol.34
, Issue.3
, pp. 377-412
-
-
Moon, H.S.1
Dalamaga, M.2
Kim, S.Y.3
Polyzos, S.A.4
Hamnvik, O.P.5
Magkos, F.6
Paruthi, J.7
Mantzoros, C.S.8
-
39
-
-
79959641960
-
Parkin' control: Regulation of PGC-1 α through PARIS in Parkinson's disease
-
2-s2.0-79959641960 10.1242/dmm.008227
-
Castillo-Quan J. I., Parkin' control: regulation of PGC-1 α through PARIS in Parkinson's disease. DMM Disease Models and Mechanisms 2011 4 4 427 429 2-s2.0-79959641960 10.1242/dmm.008227
-
(2011)
DMM Disease Models and Mechanisms
, vol.4
, Issue.4
, pp. 427-429
-
-
Castillo-Quan, J.I.1
-
40
-
-
33749042331
-
Transcriptional Repression of PGC-1α by Mutant Huntingtin Leads to Mitochondrial Dysfunction and Neurodegeneration
-
DOI 10.1016/j.cell.2006.09.015, PII S0092867406012050
-
Cui L., Jeong H., Borovecki F., Parkhurst C. N., Tanese N., Krainc D., Transcriptional repression of PGC-1 α by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration. Cell 2006 127 1 59 69 2-s2.0-33749042331 10.1016/j.cell.2006.09.015 (Pubitemid 44466642)
-
(2006)
Cell
, vol.127
, Issue.1
, pp. 59-69
-
-
Cui, L.1
Jeong, H.2
Borovecki, F.3
Parkhurst, C.N.4
Tanese, N.5
Krainc, D.6
-
41
-
-
5344252327
-
Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1α null mice
-
DOI 10.1016/j.cell.2004.09.013, PII S0092867404008864
-
Lin J., Wu P., Tarr P. T., Lindenberg K. S., St-Pierre J., Zhang C., Mootha V. K., Jäger S., Vianna C. R., Reznick R. M., Cui L., Manieri M., Donovan M. X., Wu Z., Cooper M. P., Fan M. C., Rohas L. M., Zavacki A. M., Cinti S., Shulman G. I., Lowell B. B., Krainc D., Spiegelman B. M., Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1 α null mice. Cell 2004 119 1 121 135 2-s2.0-5344252327 10.1016/j.cell.2004.09.013 (Pubitemid 39349325)
-
(2004)
Cell
, vol.119
, Issue.1
, pp. 121-135
-
-
Lin, J.1
Wu, P.-H.2
Tarr, P.T.3
Lindenberg, K.S.4
St-Pierre, J.5
Zhang, C.-Y.6
Mootha, V.K.7
Jager, S.8
Vianna, C.R.9
Reznick, R.M.10
Cui, L.11
Manieri, M.12
Donovan, M.X.13
Wu, Z.14
Cooper, M.P.15
Fan, M.C.16
Rohas, L.M.17
Zavacki, A.M.18
Cinti, S.19
Shulman, G.I.20
Lowell, B.B.21
Krainc, D.22
Spiegelman, B.M.23
more..
-
42
-
-
84875859444
-
Irisin-immunoreactivity in neural and non-neural cells of the rodent
-
10.1016/j.neuroscience.2013.02.050
-
Dun S. L., Lyu R. M., Chen Y. H., Chang J. K., Luo J. J., Dun N. J., Irisin-immunoreactivity in neural and non-neural cells of the rodent. Neuroscience 2013 240 155 162 10.1016/j.neuroscience.2013.02.050
-
(2013)
Neuroscience
, vol.240
, pp. 155-162
-
-
Dun, S.L.1
Lyu, R.M.2
Chen, Y.H.3
Chang, J.K.4
Luo, J.J.5
Dun, N.J.6
-
43
-
-
84872288553
-
Fndc5 knockdown significantly decreased neural differentiation rate of mouse embryonic stem cells
-
10.1016/j.neuroscience.2012.11.041
-
Hashemi M. S., Ghaedi K., Salamian A., Karbalaie K., Emadi-Baygi M., Tanhaei S., Nasr-Esfahani M. H., Baharvand H., Fndc5 knockdown significantly decreased neural differentiation rate of mouse embryonic stem cells. Neuroscience 2013 231 296 304 10.1016/j.neuroscience.2012.11.041
-
(2013)
Neuroscience
, vol.231
, pp. 296-304
-
-
Hashemi, M.S.1
Ghaedi, K.2
Salamian, A.3
Karbalaie, K.4
Emadi-Baygi, M.5
Tanhaei, S.6
Nasr-Esfahani, M.H.7
Baharvand, H.8
-
44
-
-
84880571772
-
Pharmacological concentrations of irisin increase cell proliferation without influencing markers of neurite outgrowth and synaptogenesis in mouse H19-7 hippocampal cell lines
-
Moon H. S., Dincer F., Mantzoros C. S., Pharmacological concentrations of irisin increase cell proliferation without influencing markers of neurite outgrowth and synaptogenesis in mouse H19-7 hippocampal cell lines. Metabolism 2013 62 8 1131 1136
-
(2013)
Metabolism
, vol.62
, Issue.8
, pp. 1131-1136
-
-
Moon, H.S.1
Dincer, F.2
Mantzoros, C.S.3
-
45
-
-
84871659929
-
Physical activity, brain plasticity, and Alzheimer's disease
-
10.1016/j.arcmed.2012.09.008
-
Erickson K. I., Weinstein A. M., Lopez O. L., Physical activity, brain plasticity, and Alzheimer's disease. Archives of Medical Research 2012 43 8 615 621 10.1016/j.arcmed.2012.09.008
-
(2012)
Archives of Medical Research
, vol.43
, Issue.8
, pp. 615-621
-
-
Erickson, K.I.1
Weinstein, A.M.2
Lopez, O.L.3
-
46
-
-
84870540270
-
Energy intake and exercise as determinants of brain health and vulnerability to injury and disease
-
Mattson M. P., Energy intake and exercise as determinants of brain health and vulnerability to injury and disease. Cell Metabolism 2012 16 6 706 722
-
(2012)
Cell Metabolism
, vol.16
, Issue.6
, pp. 706-722
-
-
Mattson, M.P.1
-
47
-
-
84869497609
-
FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. MRNA expression and circulating concentrations in response to weight loss and exercise
-
Huh J. Y., Panagiotou G., Mougios V., Brinkoetter M., Vamvini M. T., Schneider B. E., Mantzoros C. S., FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in response to weight loss and exercise. Metabolism 2012 61 12 1725 1738
-
(2012)
Metabolism
, vol.61
, Issue.12
, pp. 1725-1738
-
-
Huh, J.Y.1
Panagiotou, G.2
Mougios, V.3
Brinkoetter, M.4
Vamvini, M.T.5
Schneider, B.E.6
Mantzoros, C.S.7
-
48
-
-
84876222786
-
Irisin is expressed and produced by human muscle and adipose tissue in association with obesity and insulin resistance
-
10.1210/jc.2012-2749
-
Moreno-Navarrete J. M., Ortega F., Serrano M., Guerra E., Pardo G., Tinahones F., Ricart W., Fernandez-Real J. M., Irisin is expressed and produced by human muscle and adipose tissue in association with obesity and insulin resistance. Journal of Clinical Endocrinology & Metabolism 2013 98 4 E769 E778 10.1210/jc.2012-2749
-
(2013)
Journal of Clinical Endocrinology & Metabolism
, vol.98
, Issue.4
-
-
Moreno-Navarrete, J.M.1
Ortega, F.2
Serrano, M.3
Guerra, E.4
Pardo, G.5
Tinahones, F.6
Ricart, W.7
Fernandez-Real, J.M.8
-
50
-
-
84886769757
-
Are skeletal muscle FNDC5 gene expression and Irisin release regulated by exercise and related to health?
-
Pekkala S., Wiklund P., Hulmi J. J., Ahtiainen J. P., Horttanainen M., Pollanen E., Makela K. A., Kainulainen H., Hakkinen K., Nyman K., Alen M., Herzig K. H., Cheng S., Are skeletal muscle FNDC5 gene expression and Irisin release regulated by exercise and related to health? Journal of Physiology 2013
-
(2013)
Journal of Physiology
-
-
Pekkala, S.1
Wiklund, P.2
Hulmi, J.J.3
Ahtiainen, J.P.4
Horttanainen, M.5
Pollanen, E.6
Makela, K.A.7
Kainulainen, H.8
Hakkinen, K.9
Nyman, K.10
Alen, M.11
Herzig, K.H.12
Cheng, S.13
-
51
-
-
84887839049
-
Resistance exercise training does not affect plasma Irisin levels of hemodialysis patients
-
Moraes C., Leal V. O., Marinho S. M., Barroso S. G., Rocha G. S., Boaventura G. T., Mafra D., Resistance exercise training does not affect plasma Irisin levels of hemodialysis patients. Hormone and Metabolic Research 2013
-
(2013)
Hormone and Metabolic Research
-
-
Moraes, C.1
Leal, V.O.2
Marinho, S.M.3
Barroso, S.G.4
Rocha, G.S.5
Boaventura, G.T.6
Mafra, D.7
-
52
-
-
84888879117
-
Circulating Irisin in relation to insulin resistance and the metabolic syndrome
-
Park K. H., Zaichenko L., Brinkoetter M., Thakkar B., Sahin-Efe A., Joung K. E., Tsoukas M., Geladari E. V., Young H. J., Dincer F., Davis C. R., Crowell J. A., Mantzoros C. S., Circulating Irisin in relation to insulin resistance and the metabolic syndrome. Journal of Clinical Endocrinology & Metabolism 2013
-
(2013)
Journal of Clinical Endocrinology & Metabolism
-
-
Park, K.H.1
Zaichenko, L.2
Brinkoetter, M.3
Thakkar, B.4
Sahin-Efe, A.5
Joung, K.E.6
Tsoukas, M.7
Geladari, E.V.8
Young, H.J.9
Dincer, F.10
Davis, C.R.11
Crowell, J.A.12
Mantzoros, C.S.13
-
53
-
-
84871587312
-
Circulating levels of irisin in patients with anorexia nervosa and different stages of obesity - Correlation with body mass index
-
10.1016/j.peptides.2012.11.014
-
Stengel A., Hofmann T., Goebel-Stengel M., Elbelt U., Kobelt P., Klapp B. F., Circulating levels of irisin in patients with anorexia nervosa and different stages of obesity-correlation with body mass index. Peptides 2013 39 125 130 10.1016/j.peptides.2012.11.014
-
(2013)
Peptides
, vol.39
, pp. 125-130
-
-
Stengel, A.1
Hofmann, T.2
Goebel-Stengel, M.3
Elbelt, U.4
Kobelt, P.5
Klapp, B.F.6
-
54
-
-
84876736157
-
Serum irisin levels in new-onset type 2 diabetes
-
Choi Y. K., Kim M. K., Bae K. H., Seo H. A., Jeong J. Y., Lee W. K., Kim J. G., Lee I. K., Park K. G., Serum irisin levels in new-onset type 2 diabetes. Diabetes Research and Clinical Practice 2013 100 1 96 101
-
(2013)
Diabetes Research and Clinical Practice
, vol.100
, Issue.1
, pp. 96-101
-
-
Choi, Y.K.1
Kim, M.K.2
Bae, K.H.3
Seo, H.A.4
Jeong, J.Y.5
Lee, W.K.6
Kim, J.G.7
Lee, I.K.8
Park, K.G.9
-
55
-
-
84879915581
-
Lower circulating irisin is associated with type 2 diabetes mellitus
-
Liu J. J., Wong M. D., Toy W. C., Tan C. S., Liu S., Ng X. W., Tavintharan S., Sum C. F., Lim S. C., Lower circulating irisin is associated with type 2 diabetes mellitus. Journal of Diabetes and its Complications 2013 27 4 365 369
-
(2013)
Journal of Diabetes and Its Complications
, vol.27
, Issue.4
, pp. 365-369
-
-
Liu, J.J.1
Wong, M.D.2
Toy, W.C.3
Tan, C.S.4
Liu, S.5
Ng, X.W.6
Tavintharan, S.7
Sum, C.F.8
Lim, S.C.9
-
56
-
-
84876744461
-
Common genetic variation in the human FNDC5 locus, encoding the novel muscle-derived "browning" factor Irisin, determines insulin sensitivity
-
Staiger H., Bohm A., Scheler M., Berti L., Machann J., Schick F., Machicao F., Fritsche A., Stefan N., Weigert C., Krook A., Haring H. U., de Angelis M. H., Common genetic variation in the human FNDC5 locus, encoding the novel muscle-derived "Browning" factor Irisin, determines insulin sensitivity. PLoS One 2013 8 e61903
-
(2013)
PLoS One
, vol.8
-
-
Staiger, H.1
Bohm, A.2
Scheler, M.3
Berti, L.4
MacHann, J.5
Schick, F.6
MacHicao, F.7
Fritsche, A.8
Stefan, N.9
Weigert, C.10
Krook, A.11
Haring, H.U.12
De Angelis, M.H.13
-
57
-
-
84873512773
-
Expression of the irisin precursor FNDC5 in skeletal muscle correlates with aerobic exercise performance in patients with heart failure
-
10.1161/CIRCHEARTFAILURE.112.969543
-
Lecker S. H., Zavin A., Cao P., Arena R., Allsup K., Daniels K. M., Joseph J., Schulze P. C., Forman D. E., Expression of the irisin precursor FNDC5 in skeletal muscle correlates with aerobic exercise performance in patients with heart failure. Circulation 2012 5 812 818 10.1161/CIRCHEARTFAILURE.112. 969543
-
(2012)
Circulation
, vol.5
, pp. 812-818
-
-
Lecker, S.H.1
Zavin, A.2
Cao, P.3
Arena, R.4
Allsup, K.5
Daniels, K.M.6
Joseph, J.7
Schulze, P.C.8
Forman, D.E.9
-
58
-
-
84877129604
-
Decrease in irisin in patients with chronic kidney disease
-
Wen M. S., Wang C. Y., Lin S. L., Hung K. C., Decrease in irisin in patients with chronic kidney disease. PLoS One 2013 8 e64025
-
(2013)
PLoS One
, vol.8
-
-
Wen, M.S.1
Wang, C.Y.2
Lin, S.L.3
Hung, K.C.4
-
59
-
-
84882890178
-
Irisin is inversely associated with intrahepatic triglyceride contents in obese adults
-
10.1016/j.jhep.2013.04.030
-
Zhang H. J., Zhang X. F., Ma Z. M., Pan L. L., Chen Z., Han H. W., Han C. K., Zhuang X. J., Lu Y., Li X. J., Yang S. Y., Li X. Y., Irisin is inversely associated with intrahepatic triglyceride contents in obese adults. Journal of Hepatology 2013 59 3 557 562 10.1016/j.jhep.2013.04.030
-
(2013)
Journal of Hepatology
, vol.59
, Issue.3
, pp. 557-562
-
-
Zhang, H.J.1
Zhang, X.F.2
Ma, Z.M.3
Pan, L.L.4
Chen, Z.5
Han, H.W.6
Han, C.K.7
Zhuang, X.J.8
Lu, Y.9
Li, X.J.10
Yang, S.Y.11
Li, X.Y.12
-
60
-
-
84880570314
-
Irisin levels correlate with energy expenditure in a subgroup of humans with energy expenditure greater than predicted by fat free mass
-
Swick A. G., Orena S., O'Connor A., Irisin levels correlate with energy expenditure in a subgroup of humans with energy expenditure greater than predicted by fat free mass. Metabolism 2013 62 8 1070 1073
-
(2013)
Metabolism
, vol.62
, Issue.8
, pp. 1070-1073
-
-
Swick, A.G.1
Orena, S.2
O'Connor, A.3
-
61
-
-
84873180673
-
Interactive effects of fitness and statin treatment on mortality risk in veterans with dyslipidaemia: A cohort study
-
10.1016/S0140-6736(12)61426-3
-
Kokkinos P. F., Faselis C., Myers J., Panagiotakos D., Doumas M., Interactive effects of fitness and statin treatment on mortality risk in veterans with dyslipidaemia: a cohort study. The Lancet 2013 381 9864 394 399 10.1016/S0140-6736(12)61426-3
-
(2013)
The Lancet
, vol.381
, Issue.9864
, pp. 394-399
-
-
Kokkinos, P.F.1
Faselis, C.2
Myers, J.3
Panagiotakos, D.4
Doumas, M.5
-
62
-
-
84888859188
-
Effects of lipid-lowering drugs on irisin in human subjects in vivo and in human skeletal muscle cells ex vivo
-
Gouni-Berthold I., Berthold H. K., Huh J. Y., Berman R., Spenrath N., Krone W., Mantzoros C. S., Effects of lipid-lowering drugs on irisin in human subjects in vivo and in human skeletal muscle cells ex vivo. PLoS One 2013 8 e72858
-
(2013)
PLoS One
, vol.8
-
-
Gouni-Berthold, I.1
Berthold, H.K.2
Huh, J.Y.3
Berman, R.4
Spenrath, N.5
Krone, W.6
Mantzoros, C.S.7
-
63
-
-
84888377939
-
Evidence against a beneficial effect of Irisin in humans
-
Raschke S., Elsen M., Gassenhuber H., Sommerfeld M., Schwahn U., Brockmann B., Jung R., Wisloff U., Tjonna A. E., Raastad T., Hallen J., Norheim F., Drevon C. A., Romacho T., Eckardt K., Eckel J., Evidence against a beneficial effect of Irisin in humans. PLoS One 2013 8 e73680
-
(2013)
PLoS One
, vol.8
-
-
Raschke, S.1
Elsen, M.2
Gassenhuber, H.3
Sommerfeld, M.4
Schwahn, U.5
Brockmann, B.6
Jung, R.7
Wisloff, U.8
Tjonna, A.E.9
Raastad, T.10
Hallen, J.11
Norheim, F.12
Drevon, C.A.13
Romacho, T.14
Eckardt, K.15
Eckel, J.16
|