Free fatty acid effects on myokine production in combination with exercise mimetics

Molecular Nutrition and Food Research

Volumn 57, Issue 8, 2013, Pages 1456-1467

  Sánchez, Juana ^a   Nozhenko, Yuriy ^a   Palou, Andreu ^a   Rodríguez, Ana M ^a  

^a UNIVERSITAT DE LES ILLES BALEARS   (Spain)

Author keywords

Fat muscle crosstalk; IL15; IL6; Irisin; Muscle Cells

Indexed keywords

4 AMINOIMIDAZOLE; 4-AMINOIMIDAZOLE; 5 AMINO 4 IMIDAZOLECARBOXAMIDE; ADRENALIN; AICA RIBONUCLEOTIDE; DRUG DERIVATIVE; FATTY ACID; FIBRONECTIN; FNDC5 PROTEIN, MOUSE; IMIDAZOLE DERIVATIVE; INTERLEUKIN 15; INTERLEUKIN 6; IRISIN; PPARGC1A PROTEIN, MOUSE; RIBONUCLEOTIDE; TRANSCRIPTION FACTOR;

ANIMAL; ANIMAL EXPERIMENT; ARTICLE; CELL CULTURE; DRUG EFFECT; FAT-MUSCLE CROSSTALK; GENETICS; IL15; IL6; METABOLISM; MOUSE; MUSCLE CELL; MYOBLAST;

FAT-MUSCLE CROSSTALK; IL15; IL6; IRISIN; MUSCLE CELLS;

AMINOIMIDAZOLE CARBOXAMIDE; ANIMALS; CELLS, CULTURED; EPINEPHRINE; FATTY ACIDS, NONESTERIFIED; FIBRONECTINS; IMIDAZOLES; INTERLEUKIN-15; INTERLEUKIN-6; MICE; MUSCLE CELLS; MYOBLASTS; PHYSICAL CONDITIONING, ANIMAL; RIBONUCLEOTIDES; TRANSCRIPTION FACTORS;

EID: 84881296709     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201300126     Document Type: Article

References (51)

1. de Lange, P., Moreno, M., Silvestri, E., Lombardi, A. et al., Fuel economy in food-deprived skeletal muscle: signaling pathways and regulatory mechanisms. FASEB J. 2007, 21, 3431-3441.
2. Pedersen, B. K., Febbraio, M. A., Muscles, exercise and obesity: skeletal muscle as a secretory organ. Nat. Rev. Endocrinol. 2012, 8, 457-465.
3. Trayhurn, P., Drevon, C. A., Eckel, J., Secreted proteins from adipose tissue and skeletal muscle: adipokines, myokines and adipose/muscle cross-talk. Arch. Physiol. Biochem. 2011, 117, 47-56.
4. Pedersen, B. K., Exercise-induced myokines and their role in chronic diseases. Brain Behav. Immun. 2011, 25, 811-816.
5. Pedersen, B. K., Febbraio, M. A., Muscle as an endocrine organ: focus on muscle-derived interleukin-6. Physiol. Rev. 2008, 88, 1379-1406.
6. Argilés, J. M., López-Soriano, F. J., Busquets, S., Therapeutic potential of interleukin-15: a myokine involved in muscle wasting and adiposity. Drug Discov. Today 2009, 14, 208-213.
7. Boström, P., Wu, J., Jedrychowski, M. P., Korde, A. et al., A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Nature 2012, 481, 463-468.
8. Fischer, C. P., Hiscock, N. J., Penkowa, M., Basu, S. et al., Supplementation with vitamins C and E inhibits the release of interleukin-6 from contracting human skeletal muscle. J. Physiol. 2004, 558, 633-645.
9. Ostrowski, K., Hermann, C., Bangash, A., Schjerling, P. et al., A trauma-like elevation of plasma cytokines in humans in response to treadmill running. J. Physiol. 1998, 513 (Pt 3), 889-894.
10. Al-Khalili, L., Bouzakri, K., Glund, S., Lönnqvist, F. et al., Signaling specificity of interleukin-6 action on glucose and lipid metabolism in skeletal muscle. Mol. Endocrinol. 2006, 20, 3364-3375.
11. Carey, A. L., Steinberg, G. R., Macaulay, S. L., Thomas, W. G. et al., Interleukin-6 increases insulin-stimulated glucose disposal in humans and glucose uptake and fatty acid oxidation in vitro via AMP-activated protein kinase. Diabetes 2006, 55, 2688-2697.
12. Glund, S., Deshmukh, A., Long, Y. C., Moller, T. et al., Interleukin-6 directly increases glucose metabolism in resting human skeletal muscle. Diabetes 2007, 56, 1630-1637.
13. Kelly, M., Keller, C., Avilucea, P. R., Keller, P., et al., AMPK activity is diminished in tissues of IL-6 knockout mice: the effect of exercise. Biochem. Biophys. Res. Commun. 2004, 320, 449-454.
14. Minokoshi, Y., Kim, Y. B., Peroni, O. D., Fryer, L. G. et al., Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase. Nature 2002, 415, 339-343.
15. Steinberg, G. R., Rush, J. W., Dyck, D. J., AMPK expression and phosphorylation are increased in rodent muscle after chronic leptin treatment. Am. J. Physiol. Endocrinol. Metab. 2003, 284, E648-654.
16. Whitham, M., Chan, M. H., Pal, M., Matthews, V. B. et al., Contraction-induced interleukin-6 gene transcription in skeletal muscle is regulated by c-Jun terminal kinase/activator protein-1. J. Biol. Chem. 2012, 287, 10771-10779.
17. Petersen, E. W., Carey, A. L., Sacchetti, M., Steinberg, G. R. et al., Acute IL-6 treatment increases fatty acid turnover in elderly humans in vivo and in tissue culture in vitro. Am. J. Physiol. Endocrinol. Metab. 2005, 288, E155-E162.
18. van Hall, G., Steensberg, A., Sacchetti, M., Fischer, C. et al., Interleukin-6 stimulates lipolysis and fat oxidation in humans. J. Clin. Endocrinol. Metab. 2003, 88, 3005-3010.
19. Quinn, L. S., Haugk, K. L., Grabstein, K. H., Interleukin-15: a novel anabolic cytokine for skeletal muscle. Endocrinology 1995, 136, 3669-3672.
20. Quinn, L. S., Interleukin-15: a muscle-derived cytokine regulating fat-to-lean body composition. J. Anim. Sci. 2008, 86, E75-83.
21. Quinn, L. S., Anderson, B. G., Drivdahl, R. H., Alvarez, B. et al., Overexpression of interleukin-15 induces skeletal muscle hypertrophy in vitro: implications for treatment of muscle wasting disorders. Exp. Cell Res. 2002, 280, 55-63.
22. Almendro, V., Busquets, S., Ametller, E., Carbó, N. et al., Effects of interleukin-15 on lipid oxidation: disposal of an oral [(14)C]-triolein load. Biochim. Biophys. Acta 2006, 1761, 37-42.
23. Nielsen, A. R., Mounier, R., Plomgaard, P., Mortensen, O. H. et al., Expression of interleukin-15 in human skeletal muscle effect of exercise and muscle fibre type composition. J. Physiol. 2007, 584, 305-312.
24. Nieman, D. C., Davis, J. M., Brown, V. A., Henson, D. A. et al., Influence of carbohydrate ingestion on immune changes after 2 h of intensive resistance training. J. Appl. Physiol. 2004, 96, 1292-1298.
25. Riechman, S. E., Balasekaran, G., Roth, S. M., Ferrell, R. E., Association of interleukin-15 protein and interleukin-15 receptor genetic variation with resistance exercise training responses. J. Appl. Physiol. 2004, 97, 2214-2219.
26. Yang, H., Chang, J., Chen, W., Zhao, L. et al., Treadmill exercise promotes interleukin 15 expression in skeletal muscle and interleukin 15 receptor alpha expression in adipose tissue of high-fat diet rats. Endocrine 2012, doi: 10.1007/s12020-012-9809-6.
27. Carbó, N., López-Soriano, J., Costelli, P., Busquets, S. et al., Interleukin-15 antagonizes muscle protein waste in tumour-bearing rats. Br. J. Cancer 2000, 83, 526-531.
28. Carbó, N., López-Soriano, J., Costelli, P., Alvarez, B. et al., Interleukin-15 mediates reciprocal regulation of adipose and muscle mass: a potential role in body weight control. Biochim. Biophys. Acta 2001, 1526, 17-24.
29. Handschin, C., Spiegelman, B. M., The role of exercise and PGC1alpha in inflammation and chronic disease. Nature 2008, 454, 463-469.
30. Puigserver, P., Wu, Z., Park, C. W., Graves, R. et al., A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell 1998, 92, 829-839.
31. Huh, J. Y., Panagiotou, G., Mougios, V., Brinkoetter, M., et al., FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in response to weight loss and exercise. Metabolism 2012, 61, 1725-1738.
32. Timmons, J. A., Baar, K., Davidsen, P. K., Atherton, P. J., Is irisin a human exercise gene? Nature 2012, 488, E9-10, discussion E10-11.
33. Kelly, D. P., Medicine. Irisin, light my fire. Science 2012, 336, 42-43.
34. Galbo, H., Hormonal and Metabolic Adaptation to Exercise, Georg Thieme Verlag; Thieme-Stratton, Stuttgart, New York 1983.
35. Cantó, C., Auwerx, J., AMP-activated protein kinase and its downstream transcriptional pathways. Cell Mol. Life Sci. 2010, 67, 3407-3423.
36. Rodríguez, A. M., Sánchez, J., Tobaruela, A., Priego, T. et al., Time-course effects of increased fatty acid supply on the expression of genes involved in lipid/glucose metabolism in muscle cells. Cell Physiol. Biochem. 2010, 25, 337-346.
37. Witczak, C. A., Sharoff, C. G., Goodyear, L. J., AMP-activated protein kinase in skeletal muscle: from structure and localization to its role as a master regulator of cellular metabolism. Cell Mol. Life Sci. 2008, 65, 3737-3755.
38. Spector, A. A., Fatty acid binding to plasma albumin. J. Lipid Res. 1975, 16, 165-179.
39. Yuzefovych, L., Wilson, G., Rachek, L., Different effects of oleate vs. palmitate on mitochondrial function, apoptosis, and insulin signaling in L6 skeletal muscle cells: role of oxidative stress. Am. J. Physiol. Endocrinol. Metab. 2010, 299, E1096-E1105.
40. Picó, C., Oliver, P., Sánchez, J., Miralles, O. et al., The intake of physiological doses of leptin during lactation in rats prevents obesity in later life. Int. J. Obes. (Lond.) 2007, 31, 1199-1209.
41. Handschin, C., Choi, C. S., Chin, S., Kim, S. et al., Abnormal glucose homeostasis in skeletal muscle-specific PGC-1alpha knockout mice reveals skeletal muscle-pancreatic beta cell crosstalk. J. Clin. Invest. 2007, 117, 3463-3474.
42. Watt, M. J., Southgate, R. J., Holmes, A. G., Febbraio, M. A., Suppression of plasma free fatty acids upregulates peroxisome proliferator-activated receptor (PPAR) alpha and delta and PPAR coactivator 1alpha in human skeletal muscle, but not lipid regulatory genes. J. Mol. Endocrinol. 2004, 33, 533-544.
43. Suwa, M., Nakano, H., Kumagai, S., Effects of chronic AICAR treatment on fiber composition, enzyme activity, UCP3, and PGC-1 in rat muscles. J. Appl. Physiol. 2003, 95, 960-968.
44. Annibalini, G., Guescini, M., Agostini, D., Matteis, R. D. et al., The expression analysis of mouse interleukin-6 splice variants argued against their biological relevance. BMB Rep. 2012, 45, 32-37.
45. Frost, R. A., Nystrom, G. J., Lang, C. H., Epinephrine stimulates IL-6 expression in skeletal muscle and C2C12 myoblasts: role of c-Jun NH2-terminal kinase and histone deacetylase activity. Am. J. Physiol. Endocrinol. Metab. 2004, 286, E809-817.
46. Granados, N., Amengual, J., Ribot, J., Palou, A. et al., Distinct effects of oleic acid and its trans-isomer elaidic acid on the expression of myokines and adipokines in cell models. Br. J. Nutr. 2011, 105, 1226-1234.
47. Forman, B. M., Chen, J., Evans, R. M., Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta. Proc. Natl. Acad. Sci. USA 1997, 94, 4312-4317.
48. Narkar, V. A., Downes, M., Yu, R. T., Embler, E. et al., AMPK and PPARdelta agonists are exercise mimetics. Cell 2008, 134, 405-415.
49. Giri, J. G., Kumaki, S., Ahdieh, M., Friend, D. J. et al., Identification and cloning of a novel IL-15 binding protein that is structurally related to the alpha chain of the IL-2 receptor. EMBO J. 1995, 14, 3654-3663.
50. Bergamaschi, C., Bear, J., Rosati, M., Beach, R. K. et al., Circulating IL-15 exists as heterodimeric complex with soluble IL-15Rα in human and mouse serum. Blood 2012, 120, e1-e8.
51. Baar, K., Wende, A. R., Jones, T. E., Marison, M. et al., Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1. FASEB J. 2002, 16, 1879-1886.