Micelles of TPGS modified apigenin phospholipid complex for oral administration: Preparation, in vitro and in vivo evaluation

Journal of Biomedical Nanotechnology

Volumn 9, Issue 12, 2013, Pages 2034-2047

  Munyendo, Were L L ^a   Zhang, Zhenhai ^b   Abbad, Sarra ^a   Waddad, Ayman Y ^a   Lv, Huxia ^a   Baraza, Lilechi D ^a   Zhou, Jianping ^c  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b Jiangsu Provincial Hospital of Chinese Medicine   (China)

^c MASINDE MULIRO UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Kenya)

Author keywords

Anticancer; Apigenin; Micelles; Oral administration; Phospholipids complex; TPGS

Indexed keywords

ANTICANCER; APIGENIN; FTIR AND NMR SPECTROSCOPY; INTRACELLULAR TRAFFICKING; NEGATIVE ZETA POTENTIALS; ORAL ADMINISTRATION; ORAL BIOAVAILABILITIES; TPGS;

BIOCHEMISTRY; CELL CULTURE; COMPUTER SIMULATION; CYTOTOXICITY; ENCAPSULATION; FILM PREPARATION; FLAVONOIDS; HYDROPHOBICITY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHOSPHOLIPIDS;

MICELLES;

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; AP 1201108261; APIGENIN; MULTIDRUG RESISTANCE PROTEIN; PHOSPHOLIPID; TOCOFERSOLAN; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL MIGRATION; COMPUTER SIMULATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG DESIGN; DRUG ENCAPSULATION; DRUG INHIBITION; DRUG METABOLISM; DRUG PENETRATION; ENCAPSULATION; EXOCYTOSIS; FEMALE; FREEZE DRYING; HYDRATION; HYDROPHOBICITY; IN VITRO STUDY; IN VIVO STUDY; INFRARED SPECTROSCOPY; INTESTINE ABSORPTION; MALE; MICELLE; MORPHOLOGY; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PARTICLE SIZE; RAT; STATIC ELECTRICITY; SURFACE CHARGE; SURFACE TENSIOMETRY; ZETA POTENTIAL;

ANIMALS; APIGENIN; DRUG CARRIERS; FEMALE; HUMANS; INTESTINAL ABSORPTION; MALE; MATERIALS TESTING; MICE; MICE, NUDE; MICELLES; MOLECULAR DOCKING SIMULATION; PHOSPHOLIPIDS; POLYETHYLENE GLYCOLS; POLYMERS; RATS; RATS, SPRAGUE-DAWLEY; TUMOR CELLS, CULTURED; VITAMIN E;

EID: 84888775795     PISSN: 15507033     EISSN: 15507041     Source Type: Journal    
DOI: 10.1166/jbn.2013.1704     Document Type: Article

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