Impact of excipients on the absorption of P-glycoprotein substrates in vitro and in vivo

International Journal of Pharmaceutics

Volumn 278, Issue 1, 2004, Pages 119-131

  Cornaire, Gilles ^a   Woodley, John ^a   Hermann, Philippe ^b   Cloarec, Alix ^b   Arellano, Cécile ^a   Houin, Georges ^a,c  

^a CNRS   (France)

^b UPSA Laboratories   (France)

^c CHU RANGUEIL   (France)

Author keywords

Celiprolol; Digoxin; Everted sacs; Excipients; P glycoprotein; Surfactants

Indexed keywords

CELIPROLOL; CREMOPHOR; DIGOXIN; EXCIPIENT; GLYCOPROTEIN P; LABRASOL; MIGLYOL; POLYSORBATE 20; POLYSORBATE 80; SOLUTOL HS 15; SUCROSE LAURATE; SURFACTANT; TOCOFERSOLAN;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; INTESTINE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; DIGOXIN; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCIPIENTS; INTESTINAL ABSORPTION; INTESTINAL MUCOSA; L-LACTATE DEHYDROGENASE; MALE; P-GLYCOPROTEIN; RATS; RATS, SPRAGUE-DAWLEY;

EID: 2442671307     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2004.03.001     Document Type: Article

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