Chronic inflammation in biomaterial-induced periprosthetic osteolysis: NF-κB as a therapeutic target

Acta Biomaterialia

Volumn 10, Issue 1, 2014, Pages 1-10

  Lin, Tzu Hua ^a   Tamaki, Yasunobu ^a   Pajarinen, Jukka ^a   Waters, Heather A ^a   Woo, Deanna K ^a   Yao, Zhenyu ^a   Goodman, Stuart B ^a,b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Stanford University   (United States)

Author keywords

Biomaterials; Chronic inflammation; NF B; Periprosthetic osteolysis

Indexed keywords

ARTHROPLASTY; BIOMATERIALS; BONE; JOINT PROSTHESES; PATHOLOGY; SIGNALING;

BIOMATERIAL INDUCED; BONE DESTRUCTION; CHRONIC INFLAMMATION; IL-1Β; NF-ΚB; PERIPROSTHETIC OSTEOLYSIS; SIGNALLING PATHWAYS; THERAPEUTIC TARGETS; TNF Α; WEAR PARTICLES;

CHEMICAL ACTIVATION;

BIOMATERIAL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; OSTEOCLAST DIFFERENTIATION FACTOR; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

BONE DESTRUCTION; CELL MATURATION; CHRONIC INFLAMMATION; CYTOKINE PRODUCTION; OSSIFICATION; OSTEOCLASTOGENESIS; OSTEOLYSIS; PATHOGENESIS; PRIORITY JOURNAL; REVIEW;

BIOMATERIALS; CHRONIC INFLAMMATION; NF-ΚB; PERIPROSTHETIC OSTEOLYSIS;

ANIMALS; BIOCOMPATIBLE MATERIALS; CHRONIC DISEASE; HUMANS; INFLAMMATION; JOINT PROSTHESIS; NF-KAPPA B; OSTEOLYSIS; SIGNAL TRANSDUCTION;

EID: 84888639357     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2013.09.034     Document Type: Review

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