Bone allograft non-union is related to excessive osteoclastic bone resorption: A sheep model study

Histology and Histopathology

Volumn 21, Issue 10-12, 2006, Pages 1277-1285

  Laird, R K ^a   Pavlos, N J ^a   Xu, J ^a   Brankov, B ^a   White, B ^a   Fan, Y ^a   Papadimitriou, J M ^a   Wood, D J ^a   Zheng, M H ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Bone allograft; Bone resorption; Osteoclast; Sheep

Indexed keywords

CALCITONIN RECEPTOR; CARRIER PROTEIN; DRUG ANALYSIS; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MEMBRANE PROTEIN; MESSENGER RNA; OSTEOCLAST DIFFERENTIATION FACTOR;

ADVERSE DRUG REACTION; ALLOTRANSPLANTATION; ANIMAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE ALLOGRAFT; BONE EROSION; BONE TRANSPLANTATION; CELL ACTIVITY; CELL COUNT; CELL SHAPE; CONNECTIVE TISSUE; CONTROLLED STUDY; DISEASE MODEL; ETIOLOGY; FEMUR; FIBROBLAST; GENETICS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MONONUCLEAR CELL; MORPHOMETRICS; NONHUMAN; OSTEOCLAST; OSTEOLYSIS; PATHOLOGY; PROTEIN EXPRESSION; PSEUDARTHROSIS; SHEEP; SYNOVIOCYTE; TRANSPLANTATION;

ADVERSE EFFECTS; ANALYSIS; ANIMALS; BONE RESORPTION; BONE TRANSPLANTATION; CARRIER PROTEINS; CELL COUNT; CONNECTIVE TISSUE; ETIOLOGY; FEMUR; FIBROBLASTS; GENETICS; MEMBRANE GLYCOPROTEINS; MODELS, ANIMAL; NF-KAPPA B; OSTEOCLASTS; PATHOLOGY; RANK LIGAND; RNA, MESSENGER; SHEEP; TRANSPLANTATION; TRANSPLANTATION, HOMOLOGOUS;

OVIS ARIES;

EID: 33750357085     PISSN: 02133911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Aro H.T. and Aho A.J. (1993). Clinical use of bone allografts. Ann. Med. 25, 403-412.
2. Bonucci E. (2003). Reactions of normal and osteoporotic bone to fixation devices. In: Orthopaedic issues in osteoporosis. 1st ed. An Y.H. (ed). CRC Press. Boca Raton. pp 249-268.
3. Buck B.E. and Malinin T.I. (1994). Human bone and tissue allografts. Preparation and safety. Clin. Orthop. Relat. Res. 303, 8-17.
4. Burchardt H. (1983). The biology of bone graft repair. Clin. Orthop. Relat. Res. 174, 28-42,
5. Childs L.M., Pashalis E.P., Xing L., Dougall W.C., Anderson D., Boskey A.L., Puzas J.E., Rosier R.N., O'Keefe R.J., Boyce B.F. and Schwarz E.M. (2002). In vivo RANK signaling blockade using receptor activator of NF-kappaB:Fc effectively prevents and ameliorates wear debris-induced osteolysis via osteoclast depletion without inhibiting osteogensis. J. Bone Miner. Res. 17, 192-199.
6. Delloye C., Verhelpen M., d'Hemricourt J., Govaerts B. and Bourgois, R. (1992). Morphometric and physical investigations of segmental cortical bone autografts and allografts in canine ulnar defects. Clin. Orthop. Relat. Res. 282, 273-292.
7. Enneking W.F., Eady J.L. and Burchardt H. (1980). Autogenous cortical bone grafts in the reconstruction of segmental skeletal defects. J. Bone Joint Surg. Am. 62, 1039-1058.
8. Enneking W.F. and Mindell E.R. (1991). Observations on massive retrieved human allografts. J. Bone Joint Surg. Am. 73, 1123-1142.
9. Friedlander G.E. (1987). Morphologic and immunologic responses to bone allografts in humans: A preliminary report. In: Limb salvage in musculoskeletal oncology. Enneking W. (ed). Churchill Livingstone. New York. pp 562-566.
10. Garbuz D.S., Masri B.A. and Czitrom A.A. (1998). Biology of allografting. Orthop. Clin. North Am. 29,199-204.
11. Gie G.A., Linder L., Ling R.S., Simon J.P., Slooff T J. and Timperley A.J. (1993). Impacted cancellous allografts and cement for revision total hip arthroplasty. J. Bone Joint Surg. Br. 75, 14-21.
12. Greenfield E.M., Bi Y., Ragab A.A., Goldberg V.M. and Van De Motter R.R. (2002). The role of osteoclast differentiation in aseptic loosening. J. Orthop. Res. 20, 1-8.
13. Griffiths H.J., Anderson J.R., Thompson R.C., Amundson P. and Detlie T. (1995). Radiographic evaluation of the complications of long bone allografts. Skeletal Radiol. 24, 283-286.
14. Harrington K.D., Johnston J.O., Kaufer H.N., Luck J.V. Jr. and Moore T.M. (1986). Limb salvage and prosthetic joint reconstruction for low-grade and selected high-grade sarcomas of bone after wide resection and replacement by autoclaved [corrected] autogeneic grafts. Clin. Orthop. Relat. Res. 211, 180-214.
15. Haynes D.R., Crotti T.N., Loric M., Bain G.I., Atkins G.J. and Findlay, D.M. (2001a). Osteoprotegerin and receptor activator of nuclear factor kappaB ligand (RANKL) regulate osteoclast formation by cells in the human rheumatoid arthritic joint. Rheumatology (Oxford) 40, 623-630.
16. Haynes D.R., Crotti T.N., Potter A.E., Loric M., Atkins G.J., Howie D.W. and Findlay D. M. (2001b). The osteoclastogenic molecules RANKL and RANK are associated with periprosthetic osteolysis. J. Bone Joint Surg. Br. 83, 902-911.
17. Helfrich M.H. (2003). Osteoclast diseases. Microsc. Res. Tech. 61, 514-532.
18. Huang L., Xu J., Wood D.J. and Zheng M.H. (2000). Gene expression of osteoprotegerin ligand, osteoprotegerin, and receptor activator of NF-kappaB in giant cell tumor of bone: possible involvement in tumor cell-induced osteoclast-like cell formation. Am. J. Pathol. 156, 761-767.
19. Lacey D.L., Timms E., Tan H.L., Kelley M.J., Dunstan C.R., Burgess T., Elliott R., Colombero A., Elliott G., Scully S., Hsu H., Sullivan J., Hawkins N., Davy E., Capparelli C., Eli A., Qian Y.X., Kaufman S., Sarosi I., Shalhoub V., Senaldi G., Guo J., Delaney J. and Boyle W.J. (1998). Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell 93, 165-176.
20. Li X.Q., Stevenson S., Klein L., Davy D.T., Shaffer J. and Goldberg V.M. (1991). Differential patterns of incorporation and remodeling among various types of bone grafts. Acta. Anat. 140, 236-244.
21. Liu D., Xu, J., Figliomeni L., Huang L., Pavlos N.J., Rogers M., Tan A., Price P. and Zheng M.H. (2003). Expression of RANKL and OPG mRNA in periodontal disease: Possible involvement in bone destruction. Int. J. Mol. Med. 11, 17-21.
22. Mankin H.J., Doppelt S. and Tomford, W. (1983). Clinical experience with allograft implantation. The first ten years. Clin. Orthop. Relat. Res. 174, 69-86,
23. Martin W.R. and Sutherland C.J. (1993). Complications of proximal femoral allografts in revision total hip arthroplasty. Clin. Orthop. Relat. Res. 295, 161-167.
24. McEvoy A., Jeyam M., Ferrier G., Evans C.E. and Andrew J.G. (2002). Synergistic effect of particles and cyclic pressure on cytokine production in human monocyte/macrophages: proposed role in periprosthetic osteolysis. Bone 30, 171-177.
25. Quinn J.M., Morfis M., Lam M.H., Elliott J., Kartsogiannis V., Williams E.D., Gillespie M.T., Martin T.J. and Sexton P.M. (1999). Calcitonin receptor antibodies in the identification of osteoclasts. Bone 25, 1-8.
26. Takayanagi H., Oda H., Yamamoto S., Kawaguchi H., Tanaka S., Nishikawa T. and Koshihara Y. (1997). A new mechanism of bone destruction in rheumatoid arthritis: synovial fibroblasts induce osteoclastogenesis. Blochem. Biophys. Res. Commun. 240, 279-286.
27. Thompson R.C. Jr., Garg A., Clohisy D.R. and Cheng E.Y. (2000). Fractures in large-segment allografts. Clin. Orthop. Relat. Res. 370, 227-235.
28. Xu J., Tan J.W., Huang L., Gao X.H., Laird R., Liu D., Wysocki S. and Zheng M.H. (2000). Cloning, sequencing, and functional characterization of the rat homologue of receptor activator of NF-kappaB ligand. J. Bone Miner. Res. 15, 2178-2186.
29. Yasuda H., Shima N., Nakagawa N., Yamaguchi K., Kinosaki M., Mochizuki S., Tomoyasu A., Yano K., Goto M., Murakami A., Tsuda E., Morinaga T., Higashio K., Udagawa N., Takahashi N. and Suda T. (1998). Osteoclast differentiation factor is a ligand for osteoprotegerin/ osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. Proc. Natl. Acad. Sci. USA. 95, 3597-3602.
30. Zabka A. G., Pluhar G.E., Edwards R.B.3rd, Manley P.A., Hayashi K., Heiner J.P., Kalscheur V.L., Seeherman H.J. and Markel (2001). Histomorphometric description of allograft bone remodeling and union in a canine segmental femoral defect model: a comparison of rhBMP-2, cancellous bone graft, and absorbable collagen sponge. J. Orthop. Res. 19, 318-327.