An expedient domino three-component [3+2]-cycloaddition/annulation protocol: Regio- and stereoselective assembly of novel polycyclic hybrid heterocycles with five contiguous stereocentres

Tetrahedron Letters

Volumn 54, Issue 51, 2013, Pages 7044-7048

  Uma Maheswari, Shanmugavel ^a   Perumal, Subbu ^a  

^a MADURAI KAMARAJ UNIVERSITY   (India)

Author keywords

1,3 Dipolar cycloaddition; 2 Arylmethylidene 3,4 dihydro 1(2H) acridinones; Azomethine ylide; Domino reactions; Intramolecular aldol type reactions

Indexed keywords

1,4 NAPHTHOQUINONE DERIVATIVE; 2 [ARYLMETHYLIDENE] 3,4 DIHYDRO 1(2H) ACRIDINONES; ACRIDONE DERIVATIVE; AZOMETHINE YLIDE; HETEROCYCLIC COMPOUND; PYRROLIDINE DERIVATIVE; QUINOLINE DERIVATIVE; SARCOSINE; TIMONACIC; UNCLASSIFIED DRUG;

ALDOL REACTION; ANNULATION REACTION; ARTICLE; CLINICAL PROTOCOL; COVALENT BOND; CYCLOADDITION; DRUG SYNTHESIS; STEREOCHEMISTRY;

EID: 84888013133     PISSN: 00404039     EISSN: 18733581     Source Type: Journal    
DOI: 10.1016/j.tetlet.2013.10.074     Document Type: Article

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83. Crystallographic data (excluding structure factors) for compound 4c in this letter have been deposited with the Cambridge Crystallographic Data Centre as supplementary publication number CCDC 954127. Copies of the data can be obtained, free of charge, on application to CCDC, 12 Union Road, Cambridge CB2 1EZ, UK [fax: +44 (0)1223-336033 or e-mail: deposit@ccdc.cam.ac.uk ].