Nematocidal and trichomonacidal activities of 2-substituted quinolines

Farmaco

Volumn 60, Issue 3, 2005, Pages 219-224

  Martínez Grueiro, Mercedes ^a   Giménez Pardo, Consuelo ^b   Gómez Barrio, Alicia ^a   Franck, Xavier ^c   Fournet, Alain ^c,d   Hocquemiller, Reynald ^c   Figadère, Bruno ^c,e   Casado Escribano, Nieves ^b,e  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b UNIVERSITY OF ALCALÁ   (Spain)

^c UNIVERSITÉ PARIS SACLAY   (France)

^d Institut de Recherche Pour le Développe Ment   (France)

^e UNIVERSITÉ PARIS SUD   (France)

Author keywords

Nematocidal and Trichomonacidal activities; Substituted quinolines; Synthesis

Indexed keywords

ALBENDAZOLE; LEVAMISOLE; MEBENDAZOLE; METRONIDAZOLE; QUINOLINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTHELMINTIC ACTIVITY; ANTIPROTOZOAL ACTIVITY; ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; HELIGMOSOMOIDES POLYGYRUS; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NEMATOCIDAL ACTIVITY; NEMATODE; NEMATODIASIS; NONHUMAN; PROTOZOAL INFECTION; PROTOZOON; SINGLE DRUG DOSE; TRICHINELLA SPIRALIS; TRICHINOSIS; TRICHOMONACIDAL ACTIVITY; TRICHOMONAS VAGINALIS;

EID: 15244355255     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.farmac.2004.11.010     Document Type: Article

References (20)

1. R. Kaminsky Drug resistance in nematodes: a paper tiger or a real problem? Curr. Opin. Infect. Dis. 16 2003 559 564
2. H. Swygard, A.C. Sena, M.M. Hobbs, and M.S. Cohen Trichomoniasis: clinical manifestations, diagnosis and management Sex. Transm. Infect. 80 2004 91 95
3. A. Fournet, R. Hocquemiller, F. Roblot, A. Cav́, P. Richomme, and J. Bruneton Les chimanines, nouvelles quinoĺines substitúes en 2, isoĺes de Galipea longiflora Kr J. Nat. Prod. 56 1993 1547 1552
4. M.A. Fakhfakh, X. Franck, A. Fournet, R. Hocquemiller, and B. Figad̀re Expeditive preparation of 2-substituted quinolines Tetrahedron Lett. 42 2001 3847 3850
5. M.A. Fakhfakh, X. Franck, R. Hocquemiller, and B. Figad̀re Iron catalyzed hydrobromination of 2-aryl-1,1-dibromo-1-alkenes J. Organomet. Chem. 624 2001 131 135
6. M.A. Fakhfakh, X. Franck, A. Fournet, R. Hocquemiller, and B. Figad̀re Preparation of quinolines substituted at the 2- or 3-position by an alkenyl or alkynyl chain Synth. Commun. 32 2002 2863 2875
7. A. Fournet, M.E. Ferreira, S. Torres de Ortiz, S. Fuentes, H. Nakayama, and A. Rojas de Arias In vivo efficacy of 2-substituted quinolines in experimental treatment of New World cutaneous leishmaniasis caused by Leishmania amazonensis Antimicrob Agents Chemother 40 1996 2447 2451
8. H. Nakayama, M.E. Ferreira, A. Rojas de Arias, A.N.V. de Bilbao, A. Schinini, and A. Fournet Experimental treatment of chronic Trypanosoma cruzi infection in mice with 2-n-propylquinoline Phytother. Res. 15 2001 630 632
9. J.C. Gantier, A. Fournet, A.M.H. Munos, and R. Hocquemiller The effect of some 2-substituted quinolines isolated from Galipea longiflora on Plasmodium vinckei petteri infected mice Planta Med. 62 1996 285 286
10. K. Mekouar, J.F. Mouscadet, D. Desmaële, F. Subra, H. Leh, D. Savouŕ, C. Auclair, and J. d'Angelo Styrylquinoline derivatives: a new class of potent HIV-1 integrase inhibitors that block HIV-1 replication in CEM cells J. Med. Chem. 41 1998 2846 2857
11. F. Zouhiri, J.F. Mouscadet, K. Mekouar, D. Desmaële, D. Savouŕ, H. Leh, F. Subra, M. Le Bret, C. Auclair, and J. d'Angelo Structure-activity relationships and binding mode of styrylquinolines as potent inhibitors of HIV-1 integrase and replication of HIV-1 in cell culture J. Med. Chem. 43 2000 1533 1540
12. M.A. Fakhfakh, A. Fournet, E. Prina, J.F. Mouscadet, X. Franck, R. Hocquemiller, and B. Figad̀re Synthesis and biological evaluation of substituted quinolines: potential treatment of protozoal and retroviral co-infections Bioorg. Med. Chem. 11 2003 5013 5023
13. A. Fournet, R. Mahieux, M.A. Fakhfakh, X. Franck, R. Hocquemiller, and B. Figad̀re Substituted quinolines induce inhibition of proliferation of HTLV-1 infected cells Bioorg. Med. Chem. Lett. 13 2003 891 894
14. M. Reiter, T. Testerman, R. Miller, C. Weeks, and M. Tomai Cytokine induction in mice by the immunomodulator imiquimod J. Leuk. Biol. 55 1994 234 240
15. T.R. Hoye, P.R. Hanson, and J.R. Vyvyan A practical guide to first-order multiplet analysis in 1H NMR spectroscopy J. Org. Chem. 59 1994 4096 4103
16. K.G. Simpkin, and G.C. Coles The use of Caenorhabditis elegans for anthelmintic screening J. Chem. Tech. Biotechnol. 31 1981 66 69
17. F. Fonseca-Salamanca, M.M. Martinez-Grueiro, and A.R. Martinez-Fernandez Nematocidal activity of nitazoxanide in laboratory models Parasitol. Res. 91 2003 321 324
18. M.M. Martínez-Grueiro Acid phosphatase activity in excretion/secretion products from Heligmosomoides polygyrus adults: an indicator of the physiological status of the worms Parasitol. Res. 88 2002 946 949
19. P. Alonso-Villalobos, and M.M. Martínez-Grueiro The in vitro secretion of acetylcholinesterase by adult stages of Heligmosomoides polygyrus: the effects of broad-spectrum anthelmintics J. Vet. Med. B 47 2000 1 8
20. D. Denham, and A.R. Martinez Studies with methyridine and Trichinella spiralis. 2. The use of the drug to study the rate of larval production in mice J. Helminthol. 44 1970 357 363