Definition of an electronic profile of compounds with inhibitory activity against hematin aggregation in malaria parasite

Bioorganic and Medicinal Chemistry

Volumn 12, Issue 12, 2004, Pages 3313-3321

  Portela, César ^a   Afonso, Carlos M M ^a   Pinto, Madalena M M ^a   Ramos, Maria João ^a  

^a UNIVERSITY OF PORTO   (Portugal)

Author keywords

Antimalarial; Hematin; Hemozoin; Malaria

Indexed keywords

4 AMINOQUINOLINE; AMODIAQUINE; AMOPYROQUINE; ANTIMALARIAL AGENT; CHLOROQUINE; HALOFANTRINE; HEMATIN; MEFLOQUINE; MEPACRINE; PYRONARIDINE; QUINOLINE; TEBUQUINE; XANTHONE DERIVATIVE;

ARTICLE; DENSITY FUNCTIONAL THEORY; DETOXIFICATION; DRUG STRUCTURE; IC 50; MALARIA; PLASMODIUM; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTIMALARIALS; ELECTROSTATICS; HEMIN; INHIBITORY CONCENTRATION 50; MALARIA; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; XANTHONES;

EID: 2542443667     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2004.03.060     Document Type: Article

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