메뉴 건너뛰기




Volumn 35, Issue 12, 2013, Pages 1819-1828

Focus on the role of the CXCL12/CXCR4 chemokine axis in head and neck squamous cell carcinoma

Author keywords

epithelial to mesenchymal transition; head and neck cancer; hypoxia; invasion; metastasis; SDF 1

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; MATRIX METALLOPROTEINASE; TUMOR MARKER;

EID: 84888002961     PISSN: 10433074     EISSN: 10970347     Source Type: Journal    
DOI: 10.1002/hed.23217     Document Type: Article
Times cited : (41)

References (91)
  • 2
    • 33747153076 scopus 로고    scopus 로고
    • Racial disparities in patients with head and neck squamous cell carcinoma
    • Gourin CG, Podolsky RH,. Racial disparities in patients with head and neck squamous cell carcinoma. Laryngoscope 2006; 116: 1093-1106.
    • (2006) Laryngoscope , vol.116 , pp. 1093-1106
    • Gourin, C.G.1    Podolsky, R.H.2
  • 3
    • 63449140288 scopus 로고    scopus 로고
    • The changing face of head and neck cancer in the 21st century: The impact of HPV on the epidemiology and pathology of oral cancer
    • Westra WH,. The changing face of head and neck cancer in the 21st century: the impact of HPV on the epidemiology and pathology of oral cancer. Head Neck Pathol 2009; 3: 78-81.
    • (2009) Head Neck Pathol , vol.3 , pp. 78-81
    • Westra, W.H.1
  • 6
    • 51649085865 scopus 로고    scopus 로고
    • Platinum-based chemotherapy plus cetuximab in head and neck cancer
    • Vermorken JB, Mesia R, Rivera F, et al. Platinum-based chemotherapy plus cetuximab in head and neck cancer. N Engl J Med 2008; 359: 1116-1127.
    • (2008) N Engl J Med , vol.359 , pp. 1116-1127
    • Vermorken, J.B.1    Mesia, R.2    Rivera, F.3
  • 7
    • 0035479076 scopus 로고    scopus 로고
    • Elevated tumor lactate concentrations predict for an increased risk of metastases in head-and-neck cancer
    • Brizel DM, Schroeder T, Scher RL, et al. Elevated tumor lactate concentrations predict for an increased risk of metastases in head-and-neck cancer. Int J Radiat Oncol Biol Phys 2001; 51: 349-353.
    • (2001) Int J Radiat Oncol Biol Phys , vol.51 , pp. 349-353
    • Brizel, D.M.1    Schroeder, T.2    Scher, R.L.3
  • 10
    • 0023082510 scopus 로고
    • Tumor hypoxia: Its impact on cancer therapy
    • Moulder JE, Rockwell S,. Tumor hypoxia: its impact on cancer therapy. Cancer Metastasis Rev 1987; 5: 313-341.
    • (1987) Cancer Metastasis Rev , vol.5 , pp. 313-341
    • Moulder, J.E.1    Rockwell, S.2
  • 11
    • 0027460772 scopus 로고
    • Correlation between nodal density in contrasted scans and response to cisplatin-based chemotherapy in head and neck squamous cell cancer: A prospective validation
    • Janot F, Cvitkovic E, Piekarski JD, et al. Correlation between nodal density in contrasted scans and response to cisplatin-based chemotherapy in head and neck squamous cell cancer: a prospective validation. Head Neck 1993; 15: 222-229.
    • (1993) Head Neck , vol.15 , pp. 222-229
    • Janot, F.1    Cvitkovic, E.2    Piekarski, J.D.3
  • 12
    • 0142166332 scopus 로고    scopus 로고
    • Targeting HIF-1 for cancer therapy
    • Semenza GL,. Targeting HIF-1 for cancer therapy. Nat Rev Cancer 2003; 3: 721-732.
    • (2003) Nat Rev Cancer , vol.3 , pp. 721-732
    • Semenza, G.L.1
  • 13
    • 4043184065 scopus 로고    scopus 로고
    • Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1
    • Ceradini DJ, Kulkarni AR, Callaghan MJ, et al. Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1. Nat Med 2004; 10: 858-864.
    • (2004) Nat Med , vol.10 , pp. 858-864
    • Ceradini, D.J.1    Kulkarni, A.R.2    Callaghan, M.J.3
  • 14
    • 10744219598 scopus 로고    scopus 로고
    • Regulation of the chemokine receptor CXCR4 by hypoxia
    • Schioppa T, Uranchimeg B, Saccani A, et al. Regulation of the chemokine receptor CXCR4 by hypoxia. J Exp Med 2003; 198: 1391-1402.
    • (2003) J Exp Med , vol.198 , pp. 1391-1402
    • Schioppa, T.1    Uranchimeg, B.2    Saccani, A.3
  • 15
    • 33751256842 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1 and VEGF upregulate CXCR4 in glioblastoma: Implications for angiogenesis and glioma cell invasion
    • Zagzag D, Lukyanov Y, Lan L, et al. Hypoxia-inducible factor 1 and VEGF upregulate CXCR4 in glioblastoma: implications for angiogenesis and glioma cell invasion. Lab Invest 2006; 86: 1221-1232.
    • (2006) Lab Invest , vol.86 , pp. 1221-1232
    • Zagzag, D.1    Lukyanov, Y.2    Lan, L.3
  • 16
    • 78449300594 scopus 로고    scopus 로고
    • CXCL12/CXCR4/CXCR7 chemokine axis and cancer progression
    • Sun X, Cheng G, Hao M, et al. CXCL12/CXCR4/CXCR7 chemokine axis and cancer progression. Cancer Metastasis Rev 2010; 29: 709-722.
    • (2010) Cancer Metastasis Rev , vol.29 , pp. 709-722
    • Sun, X.1    Cheng, G.2    Hao, M.3
  • 17
    • 47749109823 scopus 로고    scopus 로고
    • The role of CXC chemokines and their receptors in cancer
    • Vandercappellen J, Van Damme J, Struyf S,. The role of CXC chemokines and their receptors in cancer. Cancer Lett 2008; 267: 226-244.
    • (2008) Cancer Lett , vol.267 , pp. 226-244
    • Vandercappellen, J.1    Van Damme, J.2    Struyf, S.3
  • 18
    • 0001825042 scopus 로고    scopus 로고
    • Chemokines and their role in tumor growth and metastasis
    • Wang JM, Deng X, Gong W, Su S,. Chemokines and their role in tumor growth and metastasis. J Immunol Methods 1998; 220: 1-17.
    • (1998) J Immunol Methods , vol.220 , pp. 1-17
    • Wang, J.M.1    Deng, X.2    Gong, W.3    Su, S.4
  • 19
    • 70449525704 scopus 로고    scopus 로고
    • Chemokines and chemokine receptors: Standing at the crossroads of immunobiology and neurobiology
    • Ransohoff RM,. Chemokines and chemokine receptors: standing at the crossroads of immunobiology and neurobiology. Immunity 2009; 31: 711-721.
    • (2009) Immunity , vol.31 , pp. 711-721
    • Ransohoff, R.M.1
  • 20
    • 0030002637 scopus 로고    scopus 로고
    • HIV-1 entry cofactor: Functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor
    • Feng Y, Broder CC, Kennedy PE, Berger EA,. HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. Science 1996; 272: 872-877.
    • (1996) Science , vol.272 , pp. 872-877
    • Feng, Y.1    Broder, C.C.2    Kennedy, P.E.3    Berger, E.A.4
  • 21
    • 0031296675 scopus 로고    scopus 로고
    • A chemokine PBSF/SDF-1 and its receptor CXCR4: Function and involvement in HIV-1 infection
    • Nagasawa T,. A chemokine PBSF/SDF-1 and its receptor CXCR4: function and involvement in HIV-1 infection. Seikagaku 1997; 69: 1373-1378.
    • (1997) Seikagaku , vol.69 , pp. 1373-1378
    • Nagasawa, T.1
  • 22
    • 0035383801 scopus 로고    scopus 로고
    • Plasma elevation of stromal cell-derived factor-1 induces mobilization of mature and immature hematopoietic progenitor and stem cells
    • Hattori K, Heissig B, Tashiro K, et al. Plasma elevation of stromal cell-derived factor-1 induces mobilization of mature and immature hematopoietic progenitor and stem cells. Blood 2001; 97: 3354-3360.
    • (2001) Blood , vol.97 , pp. 3354-3360
    • Hattori, K.1    Heissig, B.2    Tashiro, K.3
  • 23
    • 0032104460 scopus 로고    scopus 로고
    • A novel CXC chemokine PBSF/SDF-1 and its receptor CXCR4: Their functions in development, hematopoiesis and HIV infection
    • Nagasawa T, Tachibana K, Kishimoto T,. A novel CXC chemokine PBSF/SDF-1 and its receptor CXCR4: their functions in development, hematopoiesis and HIV infection. Semin Immunol 1998; 10: 179-185.
    • (1998) Semin Immunol , vol.10 , pp. 179-185
    • Nagasawa, T.1    Tachibana, K.2    Kishimoto, T.3
  • 24
    • 2342591450 scopus 로고    scopus 로고
    • The significance of cancer cell expression of the chemokine receptor CXCR4
    • Balkwill F,. The significance of cancer cell expression of the chemokine receptor CXCR4. Semin Cancer Biol 2004; 14: 171-179.
    • (2004) Semin Cancer Biol , vol.14 , pp. 171-179
    • Balkwill, F.1
  • 25
    • 0038206771 scopus 로고    scopus 로고
    • The stromal derived factor-1/CXCL12-CXC chemokine receptor 4 biological axis in non-small cell lung cancer metastases
    • Phillips RJ, Burdick MD, Lutz M, Belperio JA, Keane MP, Strieter RM,. The stromal derived factor-1/CXCL12-CXC chemokine receptor 4 biological axis in non-small cell lung cancer metastases. Am J Respir Crit Care Med 2003; 167: 1676-1686.
    • (2003) Am J Respir Crit Care Med , vol.167 , pp. 1676-1686
    • Phillips, R.J.1    Burdick, M.D.2    Lutz, M.3    Belperio, J.A.4    Keane, M.P.5    Strieter, R.M.6
  • 26
    • 9244234390 scopus 로고    scopus 로고
    • CXCR4 regulates growth of both primary and metastatic breast cancer
    • Smith MC, Luker KE, Garbow JR, et al. CXCR4 regulates growth of both primary and metastatic breast cancer. Cancer Res 2004; 64: 8604-8612.
    • (2004) Cancer Res , vol.64 , pp. 8604-8612
    • Smith, M.C.1    Luker, K.E.2    Garbow, J.R.3
  • 27
    • 33751319000 scopus 로고    scopus 로고
    • Stromal derived factor-1 (SDF-1/CXCL12) and CXCR4 in renal cell carcinoma metastasis
    • Pan J, Mestas J, Burdick MD, et al. Stromal derived factor-1 (SDF-1/CXCL12) and CXCR4 in renal cell carcinoma metastasis. Mol Cancer 2006; 5:Art. 56.
    • (2006) Mol Cancer , vol.5
    • Pan, J.1    Mestas, J.2    Burdick, M.D.3
  • 28
    • 18544373080 scopus 로고    scopus 로고
    • CXCR4/CXCL12 expression and signalling in kidney cancer
    • Schrader AJ, Lechner O, Templin M, et al. CXCR4/CXCL12 expression and signalling in kidney cancer. Br J Cancer 2002; 86: 1250-1256.
    • (2002) Br J Cancer , vol.86 , pp. 1250-1256
    • Schrader, A.J.1    Lechner, O.2    Templin, M.3
  • 30
    • 0033818476 scopus 로고    scopus 로고
    • Expression of stromal cell-derived factor 1 and CXCR4 ligand receptor system in pancreatic cancer: A possible role for tumor progression
    • Koshiba T, Hosotani R, Miyamoto Y, et al. Expression of stromal cell-derived factor 1 and CXCR4 ligand receptor system in pancreatic cancer: a possible role for tumor progression. Clin Cancer Res 2000; 6: 3530-3535.
    • (2000) Clin Cancer Res , vol.6 , pp. 3530-3535
    • Koshiba, T.1    Hosotani, R.2    Miyamoto, Y.3
  • 31
    • 55449122209 scopus 로고    scopus 로고
    • Chemokine receptor CXCR4-prognostic factor for gastrointestinal tumors
    • Schimanski CC, Galle PR, Moehler M,. Chemokine receptor CXCR4-prognostic factor for gastrointestinal tumors. World J Gastroenterol 2008; 14: 4721-4724.
    • (2008) World J Gastroenterol , vol.14 , pp. 4721-4724
    • Schimanski, C.C.1    Galle, P.R.2    Moehler, M.3
  • 32
    • 51049099407 scopus 로고    scopus 로고
    • Involvement of CXCL12 and CXCR4 in lymph node metastases and development of oral squamous cell carcinomas
    • Oliveira-Neto HH, Silva ET, Leles CR, et al. Involvement of CXCL12 and CXCR4 in lymph node metastases and development of oral squamous cell carcinomas. Tumour Biol 2008; 29: 262-271.
    • (2008) Tumour Biol , vol.29 , pp. 262-271
    • Oliveira-Neto, H.H.1    Silva, E.T.2    Leles, C.R.3
  • 33
    • 10044250197 scopus 로고    scopus 로고
    • The clinicopathological significance of the expression of CXCR4 protein in oral squamous cell carcinoma
    • Almofti A, Uchida D, Begum NM, et al. The clinicopathological significance of the expression of CXCR4 protein in oral squamous cell carcinoma. Int J Oncol 2004; 25: 65-71.
    • (2004) Int J Oncol , vol.25 , pp. 65-71
    • Almofti, A.1    Uchida, D.2    Begum, N.M.3
  • 34
    • 33344464945 scopus 로고    scopus 로고
    • CXCR4: A key receptor in the crosstalk between tumor cells and their microenvironment
    • Burger JA, Kipps TJ,. CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment. Blood 2006; 107: 1761-1767.
    • (2006) Blood , vol.107 , pp. 1761-1767
    • Burger, J.A.1    Kipps, T.J.2
  • 35
    • 77953090345 scopus 로고    scopus 로고
    • CXCL12 (SDF-1)/CXCR4 pathway in cancer
    • Teicher BA, Fricker SP,. CXCL12 (SDF-1)/CXCR4 pathway in cancer. Clin Cancer Res 2010; 16: 2927-2931.
    • (2010) Clin Cancer Res , vol.16 , pp. 2927-2931
    • Teicher, B.A.1    Fricker, S.P.2
  • 36
    • 58149332686 scopus 로고    scopus 로고
    • Translating an antagonist of chemokine receptor CXCR4: From bench to bedside
    • Wong D, Korz W,. Translating an antagonist of chemokine receptor CXCR4: from bench to bedside. Clin Cancer Res 2008; 14: 7975-7980.
    • (2008) Clin Cancer Res , vol.14 , pp. 7975-7980
    • Wong, D.1    Korz, W.2
  • 37
    • 85027927015 scopus 로고    scopus 로고
    • Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists
    • Wu B, Chien EY, Mol CD, et al. Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists. Science 2010; 330: 1066-1071.
    • (2010) Science , vol.330 , pp. 1066-1071
    • Wu, B.1    Chien, E.Y.2    Mol, C.D.3
  • 38
    • 77953149880 scopus 로고    scopus 로고
    • Autocrine induction of invasive and metastatic phenotypes by the MIF-CXCR4 axis in drug-resistant human colon cancer cells
    • Dessein AF, Stechly L, Jonckheere N, et al. Autocrine induction of invasive and metastatic phenotypes by the MIF-CXCR4 axis in drug-resistant human colon cancer cells. Cancer Res 2010; 70: 4644-4654.
    • (2010) Cancer Res , vol.70 , pp. 4644-4654
    • Dessein, A.F.1    Stechly, L.2    Jonckheere, N.3
  • 39
    • 70449434574 scopus 로고    scopus 로고
    • Role of chemokines and their receptors in cancer
    • Kruizinga RC, Bestebroer J, Berghuis P, et al. Role of chemokines and their receptors in cancer. Curr Pharm Des 2009; 15: 3396-3416.
    • (2009) Curr Pharm des , vol.15 , pp. 3396-3416
    • Kruizinga, R.C.1    Bestebroer, J.2    Berghuis, P.3
  • 40
    • 77954642877 scopus 로고    scopus 로고
    • CXC chemokines in cancer angiogenesis and metastases
    • Keeley EC, Mehrad B, Strieter RM,. CXC chemokines in cancer angiogenesis and metastases. Adv Cancer Res 2010; 106: 91-111.
    • (2010) Adv Cancer Res , vol.106 , pp. 91-111
    • Keeley, E.C.1    Mehrad, B.2    Strieter, R.M.3
  • 42
    • 1942442183 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1alpha promotes melanoma cell invasion across basement membranes involving stimulation of membrane-type 1 matrix metalloproteinase and Rho GTPase activities
    • Bartolome RA, Galvez BG, Longo N, et al. Stromal cell-derived factor-1alpha promotes melanoma cell invasion across basement membranes involving stimulation of membrane-type 1 matrix metalloproteinase and Rho GTPase activities. Cancer Res 2004; 64: 2534-2543.
    • (2004) Cancer Res , vol.64 , pp. 2534-2543
    • Bartolome, R.A.1    Galvez, B.G.2    Longo, N.3
  • 43
    • 25844480604 scopus 로고    scopus 로고
    • CXCR4 and CXCL12 are inversely expressed in colorectal cancer cells and modulate cancer cell migration, invasion and MMP-9 activation
    • Brand S, Dambacher J, Beigel F, et al. CXCR4 and CXCL12 are inversely expressed in colorectal cancer cells and modulate cancer cell migration, invasion and MMP-9 activation. Exp Cell Res 2005; 310: 117-130.
    • (2005) Exp Cell Res , vol.310 , pp. 117-130
    • Brand, S.1    Dambacher, J.2    Beigel, F.3
  • 44
    • 34247130586 scopus 로고    scopus 로고
    • Involvement of matrix metalloproteinase-13 in stromal-cell-derived factor 1 alpha-directed invasion of human basal cell carcinoma cells
    • Chu CY, Cha ST, Chang CC, et al. Involvement of matrix metalloproteinase-13 in stromal-cell-derived factor 1 alpha-directed invasion of human basal cell carcinoma cells. Oncogene 2007; 26: 2491-2501.
    • (2007) Oncogene , vol.26 , pp. 2491-2501
    • Chu, C.Y.1    Cha, S.T.2    Chang, C.C.3
  • 46
    • 58049192716 scopus 로고    scopus 로고
    • A cross-talk between stromal cell-derived factor-1 and transforming growth factor-beta controls the quiescence/cycling switch of CD34(+) progenitors through FoxO3 and mammalian target of rapamycin
    • Chabanon A, Desterke C, Rodenburger E, et al. A cross-talk between stromal cell-derived factor-1 and transforming growth factor-beta controls the quiescence/cycling switch of CD34(+) progenitors through FoxO3 and mammalian target of rapamycin. Stem Cells 2008; 26: 3150-3161.
    • (2008) Stem Cells , vol.26 , pp. 3150-3161
    • Chabanon, A.1    Desterke, C.2    Rodenburger, E.3
  • 47
    • 0032948123 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and basic fibroblast growth factor induce expression of CXCR4 on human endothelial cells: In vivo neovascularization induced by stromal-derived factor-1alpha
    • Salcedo R, Wasserman K, Young HA, et al. Vascular endothelial growth factor and basic fibroblast growth factor induce expression of CXCR4 on human endothelial cells: in vivo neovascularization induced by stromal-derived factor-1alpha. Am J Pathol 1999; 154: 1125-1135.
    • (1999) Am J Pathol , vol.154 , pp. 1125-1135
    • Salcedo, R.1    Wasserman, K.2    Young, H.A.3
  • 48
    • 0034666724 scopus 로고    scopus 로고
    • SDF-1 activity on microvascular endothelial cells: Consequences on angiogenesis in in vitro and in vivo models
    • Mirshahi F, Pourtau J, Li H, et al. SDF-1 activity on microvascular endothelial cells: consequences on angiogenesis in in vitro and in vivo models. Thromb Res 2000; 99: 587-594.
    • (2000) Thromb Res , vol.99 , pp. 587-594
    • Mirshahi, F.1    Pourtau, J.2    Li, H.3
  • 49
    • 19944431949 scopus 로고    scopus 로고
    • CXCL12 and vascular endothelial growth factor synergistically induce neoangiogenesis in human ovarian cancers
    • Kryczek I, Lange A, Mottram P, et al. CXCL12 and vascular endothelial growth factor synergistically induce neoangiogenesis in human ovarian cancers. Cancer Res 2005; 65: 465-472.
    • (2005) Cancer Res , vol.65 , pp. 465-472
    • Kryczek, I.1    Lange, A.2    Mottram, P.3
  • 50
    • 34250323467 scopus 로고    scopus 로고
    • CXCR4/CXCL12 axis promotes VEGF-mediated tumor angiogenesis through Akt signaling pathway
    • Liang Z, Brooks J, Willard M, et al. CXCR4/CXCL12 axis promotes VEGF-mediated tumor angiogenesis through Akt signaling pathway. Biochem Biophys Res Commun 2007; 359: 716-722.
    • (2007) Biochem Biophys Res Commun , vol.359 , pp. 716-722
    • Liang, Z.1    Brooks, J.2    Willard, M.3
  • 52
    • 42549134455 scopus 로고    scopus 로고
    • Role of Twist in head and neck carcinoma with lymph node metastasis
    • Ou DL, Chien HF, Chen CL, Lin TC, Lin LI,. Role of Twist in head and neck carcinoma with lymph node metastasis. Anticancer Res 2008; 28: 1355-1359.
    • (2008) Anticancer Res , vol.28 , pp. 1355-1359
    • Ou, D.L.1    Chien, H.F.2    Chen, C.L.3    Lin, T.C.4    Lin, L.I.5
  • 53
    • 84887996787 scopus 로고    scopus 로고
    • Prognostic value of the chemokine receptor CXCR4 and epithelial-to- mesenchymal transition in patients with squamous cell carcinoma of the mobile tongue
    • Albert S, Hourseau M, Halimi C, et al. Prognostic value of the chemokine receptor CXCR4 and epithelial-to-mesenchymal transition in patients with squamous cell carcinoma of the mobile tongue. Oral Oncol 2012; 35: 312-321.
    • (2012) Oral Oncol , vol.35 , pp. 312-321
    • Albert, S.1    Hourseau, M.2    Halimi, C.3
  • 54
    • 33644798943 scopus 로고    scopus 로고
    • CXCR4 expression is associated with lymph-node metastasis of oral squamous cell carcinoma
    • Ishikawa T, Nakashiro K, Hara S, et al. CXCR4 expression is associated with lymph-node metastasis of oral squamous cell carcinoma. Int J Oncol 2006; 28: 61-66.
    • (2006) Int J Oncol , vol.28 , pp. 61-66
    • Ishikawa, T.1    Nakashiro, K.2    Hara, S.3
  • 55
    • 49649102137 scopus 로고    scopus 로고
    • CXCL12/CXCR4 promotes laryngeal and hypopharyngeal squamous cell carcinoma metastasis through MMP-13-dependent invasion via the ERK1/2/AP-1 pathway
    • Tan CT, Chu CY, Lu YC, et al. CXCL12/CXCR4 promotes laryngeal and hypopharyngeal squamous cell carcinoma metastasis through MMP-13-dependent invasion via the ERK1/2/AP-1 pathway. Carcinogenesis 2008; 29: 1519-1527.
    • (2008) Carcinogenesis , vol.29 , pp. 1519-1527
    • Tan, C.T.1    Chu, C.Y.2    Lu, Y.C.3
  • 56
    • 0142121466 scopus 로고    scopus 로고
    • Possible role of stromal-cell-derived factor-1/CXCR4 signaling on lymph node metastasis of oral squamous cell carcinoma
    • Uchida D, Begum NM, Almofti A, et al. Possible role of stromal-cell-derived factor-1/CXCR4 signaling on lymph node metastasis of oral squamous cell carcinoma. Exp Cell Res 2003; 290: 289-302.
    • (2003) Exp Cell Res , vol.290 , pp. 289-302
    • Uchida, D.1    Begum, N.M.2    Almofti, A.3
  • 57
    • 17144413337 scopus 로고    scopus 로고
    • Expression of CXCR4 and its down-regulation by IFN-gamma in head and neck squamous cell carcinoma
    • Katayama A, Ogino T, Bandoh N, Nonaka S, Harabuchi Y,. Expression of CXCR4 and its down-regulation by IFN-gamma in head and neck squamous cell carcinoma. Clin Cancer Res 2005; 11: 2937-2946.
    • (2005) Clin Cancer Res , vol.11 , pp. 2937-2946
    • Katayama, A.1    Ogino, T.2    Bandoh, N.3    Nonaka, S.4    Harabuchi, Y.5
  • 58
    • 84869491433 scopus 로고    scopus 로고
    • Expression and clinical significance of chemokine receptor 4 in oral squamous cell carcinoma
    • Yin D, Gao Z,. Expression and clinical significance of chemokine receptor 4 in oral squamous cell carcinoma. Hua Xi Kou Qiang Yi Xue Za Zhi 2007; 25: 392-395.
    • (2007) Hua Xi Kou Qiang Yi Xue Za Zhi , vol.25 , pp. 392-395
    • Yin, D.1    Gao, Z.2
  • 59
    • 34547111065 scopus 로고    scopus 로고
    • Involvement of an autocrine stromal cell derived factor-1/CXCR4 system on the distant metastasis of human oral squamous cell carcinoma
    • Uchida D, Onoue T, Tomizuka Y, et al. Involvement of an autocrine stromal cell derived factor-1/CXCR4 system on the distant metastasis of human oral squamous cell carcinoma. Mol Cancer Res 2007; 5: 685-694.
    • (2007) Mol Cancer Res , vol.5 , pp. 685-694
    • Uchida, D.1    Onoue, T.2    Tomizuka, Y.3
  • 60
    • 79953319891 scopus 로고    scopus 로고
    • Expression of chemokine receptor CXCR4 and CCR7 in laryngeal carcinoma
    • Zhang L, Yang C, Li M,. Expression of chemokine receptor CXCR4 and CCR7 in laryngeal carcinoma. Lin Chuang Er Bi Yan Hou Ke Za Zhi 2005; 19: 985-987, 991.
    • (2005) Lin Chuang Er Bi Yan Hou Ke Za Zhi , vol.19 , pp. 985-987
    • Zhang, L.1    Yang, C.2    Li, M.3
  • 61
    • 0347419442 scopus 로고    scopus 로고
    • Investigation of CXCR4 in squamous cell carcinoma of the tongue
    • Delilbasi CB, Okura M, Iida S, Kogo M,. Investigation of CXCR4 in squamous cell carcinoma of the tongue. Oral Oncol 2004; 40: 154-157.
    • (2004) Oral Oncol , vol.40 , pp. 154-157
    • Delilbasi, C.B.1    Okura, M.2    Iida, S.3    Kogo, M.4
  • 62
    • 77950090243 scopus 로고    scopus 로고
    • Expression of CC-chemokine receptor 7 (CCR7) and CXC-chemokine receptor 4 (CXCR4) in head and neck squamous cell carcinoma
    • Ueda M, Shimada T, Goto Y, et al. Expression of CC-chemokine receptor 7 (CCR7) and CXC-chemokine receptor 4 (CXCR4) in head and neck squamous cell carcinoma. Auris Nasus Larynx 2010; 37: 488-495.
    • (2010) Auris Nasus Larynx , vol.37 , pp. 488-495
    • Ueda, M.1    Shimada, T.2    Goto, Y.3
  • 63
    • 0030742284 scopus 로고    scopus 로고
    • Development of distant metastasis after treatment of advanced-stage head and neck cancer
    • Alvi A, Johnson JT,. Development of distant metastasis after treatment of advanced-stage head and neck cancer. Head Neck 1997; 19: 500-505.
    • (1997) Head Neck , vol.19 , pp. 500-505
    • Alvi, A.1    Johnson, J.T.2
  • 64
    • 80054807678 scopus 로고    scopus 로고
    • Intratumoural level of SDF-1 correlates with survival in head and neck squamous cell carcinoma
    • Clatot F, Picquenot JM, Choussy O, et al. Intratumoural level of SDF-1 correlates with survival in head and neck squamous cell carcinoma. Oral Oncol 2011; 47: 1062-1068.
    • (2011) Oral Oncol , vol.47 , pp. 1062-1068
    • Clatot, F.1    Picquenot, J.M.2    Choussy, O.3
  • 65
    • 4444322817 scopus 로고    scopus 로고
    • CXCR4-mediated adhesion and MMP-9 secretion in head and neck squamous cell carcinoma
    • Samara GJ, Lawrence DM, Chiarelli CJ, et al. CXCR4-mediated adhesion and MMP-9 secretion in head and neck squamous cell carcinoma. Cancer Lett 2004; 214: 231-241.
    • (2004) Cancer Lett , vol.214 , pp. 231-241
    • Samara, G.J.1    Lawrence, D.M.2    Chiarelli, C.J.3
  • 66
    • 50649083968 scopus 로고    scopus 로고
    • SDF-1alpha promotes invasion of head and neck squamous cell carcinoma by activating NF-kappaB
    • Rehman AO, Wang CY,. SDF-1alpha promotes invasion of head and neck squamous cell carcinoma by activating NF-kappaB. J Biol Chem 2008; 283: 19888-19894.
    • (2008) J Biol Chem , vol.283 , pp. 19888-19894
    • Rehman, A.O.1    Wang, C.Y.2
  • 67
    • 58449097297 scopus 로고    scopus 로고
    • CXCR-4 knockdown by small interfering RNA inhibits cell proliferation and invasion of oral squamous cell carcinoma cells
    • Hong JS, Pai HK, Hong KO, et al. CXCR-4 knockdown by small interfering RNA inhibits cell proliferation and invasion of oral squamous cell carcinoma cells. J Oral Pathol Med 2009; 38: 214-219.
    • (2009) J Oral Pathol Med , vol.38 , pp. 214-219
    • Hong, J.S.1    Pai, H.K.2    Hong, K.O.3
  • 68
    • 84856525336 scopus 로고    scopus 로고
    • RNAi targeting CXCR4 inhibits tumor growth through inducing cell cycle arrest and apoptosis
    • Yu T, Wu Y, Huang Y, et al. RNAi targeting CXCR4 inhibits tumor growth through inducing cell cycle arrest and apoptosis. Mol Ther 2011; 20: 398-407.
    • (2011) Mol Ther , vol.20 , pp. 398-407
    • Yu, T.1    Wu, Y.2    Huang, Y.3
  • 69
    • 34547634399 scopus 로고    scopus 로고
    • CXC chemokine receptor-4 antagonist blocks both growth of primary tumor and metastasis of head and neck cancer in xenograft mouse models
    • Yoon Y, Liang Z, Zhang X, et al. CXC chemokine receptor-4 antagonist blocks both growth of primary tumor and metastasis of head and neck cancer in xenograft mouse models. Cancer Res 2007; 67: 7518-7524.
    • (2007) Cancer Res , vol.67 , pp. 7518-7524
    • Yoon, Y.1    Liang, Z.2    Zhang, X.3
  • 70
    • 77955355932 scopus 로고    scopus 로고
    • CXCL12/SDF-1 alpha activates NF-kappaB and promotes oral cancer invasion through the Carma3/Bcl10/Malt1 complex
    • Rehman AO, Wang CY,. CXCL12/SDF-1 alpha activates NF-kappaB and promotes oral cancer invasion through the Carma3/Bcl10/Malt1 complex. Int J Oral Sci 2009; 1: 105-118.
    • (2009) Int J Oral Sci , vol.1 , pp. 105-118
    • Rehman, A.O.1    Wang, C.Y.2
  • 71
    • 53249130662 scopus 로고    scopus 로고
    • Molecular signature and therapeutic perspective of the epithelial-to-mesenchymal transitions in epithelial cancers
    • Sabbah M, Emami S, Redeuilh G, et al. Molecular signature and therapeutic perspective of the epithelial-to-mesenchymal transitions in epithelial cancers. Drug Resist Updat 2008; 11: 123-151.
    • (2008) Drug Resist Updat , vol.11 , pp. 123-151
    • Sabbah, M.1    Emami, S.2    Redeuilh, G.3
  • 72
    • 34347330516 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition induced by the stromal cell-derived factor-1/CXCR4 system in oral squamous cell carcinoma cells
    • Onoue T, Uchida D, Begum NM, Tomizuka Y, Yoshida H, Sato M,. Epithelial-mesenchymal transition induced by the stromal cell-derived factor-1/CXCR4 system in oral squamous cell carcinoma cells. Int J Oncol 2006; 29: 1133-1138.
    • (2006) Int J Oncol , vol.29 , pp. 1133-1138
    • Onoue, T.1    Uchida, D.2    Begum, N.M.3    Tomizuka, Y.4    Yoshida, H.5    Sato, M.6
  • 73
    • 43849086665 scopus 로고    scopus 로고
    • Up-regulation of stromal cell-derived factor-1alpha and its receptor CXCR4 expression accompanied with epithelial-mesenchymal transition in human oral squamous cell carcinoma
    • Taki M, Higashikawa K, Yoneda S, et al. Up-regulation of stromal cell-derived factor-1alpha and its receptor CXCR4 expression accompanied with epithelial-mesenchymal transition in human oral squamous cell carcinoma. Oncol Rep 2008; 19: 993-998.
    • (2008) Oncol Rep , vol.19 , pp. 993-998
    • Taki, M.1    Higashikawa, K.2    Yoneda, S.3
  • 74
    • 0037462477 scopus 로고    scopus 로고
    • Twist regulates cytokine gene expression through a negative feedback loop that represses NF-kappaB activity
    • Sosic D, Richardson JA, Yu K, Ornitz DM, Olson EN,. Twist regulates cytokine gene expression through a negative feedback loop that represses NF-kappaB activity. Cell 2003; 112: 169-180.
    • (2003) Cell , vol.112 , pp. 169-180
    • Sosic, D.1    Richardson, J.A.2    Yu, K.3    Ornitz, D.M.4    Olson, E.N.5
  • 75
    • 77956301181 scopus 로고    scopus 로고
    • Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs): Positive and negative regulators in tumor cell adhesion
    • Bourboulia D, Stetler-Stevenson WG,. Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs): positive and negative regulators in tumor cell adhesion. Semin Cancer Biol 2010; 20: 161-168.
    • (2010) Semin Cancer Biol , vol.20 , pp. 161-168
    • Bourboulia, D.1    Stetler-Stevenson, W.G.2
  • 76
    • 0034997035 scopus 로고    scopus 로고
    • The role of matrix metalloproteinases in tumor invasion, metastasis, and angiogenesis
    • Stetler-Stevenson WG,. The role of matrix metalloproteinases in tumor invasion, metastasis, and angiogenesis. Surg Oncol Clin N Am 2001; 10: 383-392.
    • (2001) Surg Oncol Clin N Am , vol.10 , pp. 383-392
    • Stetler-Stevenson, W.G.1
  • 77
    • 79951841782 scopus 로고    scopus 로고
    • CXCR4 promotes oral squamous cell carcinoma migration and invasion through inducing expression of MMP-9 and MMP-13 via the ERK signaling pathway
    • Yu T, Wu Y, Helman JI, Wen Y, Wang C, Li L,. CXCR4 promotes oral squamous cell carcinoma migration and invasion through inducing expression of MMP-9 and MMP-13 via the ERK signaling pathway. Mol Cancer Res 2011; 9: 161-172.
    • (2011) Mol Cancer Res , vol.9 , pp. 161-172
    • Yu, T.1    Wu, Y.2    Helman, J.I.3    Wen, Y.4    Wang, C.5    Li, L.6
  • 78
    • 0036512208 scopus 로고    scopus 로고
    • New functions for the matrix metalloproteinases in cancer progression
    • Egeblad M, Werb Z,. New functions for the matrix metalloproteinases in cancer progression. Nat Rev Cancer 2002; 2: 161-174.
    • (2002) Nat Rev Cancer , vol.2 , pp. 161-174
    • Egeblad, M.1    Werb, Z.2
  • 79
    • 10044252233 scopus 로고    scopus 로고
    • Acquisition of lymph node, but not distant metastatic potentials, by the overexpression of CXCR4 in human oral squamous cell carcinoma
    • Uchida D, Begum NM, Tomizuka Y, et al. Acquisition of lymph node, but not distant metastatic potentials, by the overexpression of CXCR4 in human oral squamous cell carcinoma. Lab Invest 2004; 84: 1538-1546.
    • (2004) Lab Invest , vol.84 , pp. 1538-1546
    • Uchida, D.1    Begum, N.M.2    Tomizuka, Y.3
  • 80
    • 34548295350 scopus 로고    scopus 로고
    • Expression of CC chemokine receptor 7 in tonsillar cancer predicts cervical nodal metastasis, systemic relapse and survival
    • Pitkin L, Luangdilok S, Corbishley C, et al. Expression of CC chemokine receptor 7 in tonsillar cancer predicts cervical nodal metastasis, systemic relapse and survival. Br J Cancer 2007; 97: 670-677.
    • (2007) Br J Cancer , vol.97 , pp. 670-677
    • Pitkin, L.1    Luangdilok, S.2    Corbishley, C.3
  • 81
    • 67349255226 scopus 로고    scopus 로고
    • Expression of chemokine receptor CCR7 is associated with cervical lymph node metastasis of oral squamous cell carcinoma
    • Shang ZJ, Liu K, Shao Z,. Expression of chemokine receptor CCR7 is associated with cervical lymph node metastasis of oral squamous cell carcinoma. Oral Oncol 2009; 45: 480-485.
    • (2009) Oral Oncol , vol.45 , pp. 480-485
    • Shang, Z.J.1    Liu, K.2    Shao, Z.3
  • 82
    • 41749086697 scopus 로고    scopus 로고
    • Autocrine and paracrine chemokine receptor 7 activation in head and neck cancer: Implications for therapy
    • Wang J, Seethala RR, Zhang Q, et al. Autocrine and paracrine chemokine receptor 7 activation in head and neck cancer: implications for therapy. J Natl Cancer Inst 2008; 100: 502-512.
    • (2008) J Natl Cancer Inst , vol.100 , pp. 502-512
    • Wang, J.1    Seethala, R.R.2    Zhang, Q.3
  • 83
    • 1642290776 scopus 로고    scopus 로고
    • Expression pattern of chemokine receptor 6 (CCR6) and CCR7 in squamous cell carcinoma of the head and neck identifies a novel metastatic phenotype
    • Wang J, Xi L, Hunt JL, et al. Expression pattern of chemokine receptor 6 (CCR6) and CCR7 in squamous cell carcinoma of the head and neck identifies a novel metastatic phenotype. Cancer Res 2004; 64: 1861-1866.
    • (2004) Cancer Res , vol.64 , pp. 1861-1866
    • Wang, J.1    Xi, L.2    Hunt, J.L.3
  • 84
    • 33644511733 scopus 로고    scopus 로고
    • Oral and oropharyngeal squamous cell carcinomas expressing CCR7 have poor prognoses
    • Tsuzuki H, Takahashi N, Kojima A, et al. Oral and oropharyngeal squamous cell carcinomas expressing CCR7 have poor prognoses. Auris Nasus Larynx 2006; 33: 37-42.
    • (2006) Auris Nasus Larynx , vol.33 , pp. 37-42
    • Tsuzuki, H.1    Takahashi, N.2    Kojima, A.3
  • 85
    • 51649105726 scopus 로고    scopus 로고
    • Roles of CXCL8 in squamous cell carcinoma proliferation and migration
    • Christofakis EP, Miyazaki H, Rubink DS, Yeudall WA,. Roles of CXCL8 in squamous cell carcinoma proliferation and migration. Oral Oncol 2008; 44: 920-926.
    • (2008) Oral Oncol , vol.44 , pp. 920-926
    • Christofakis, E.P.1    Miyazaki, H.2    Rubink, D.S.3    Yeudall, W.A.4
  • 86
    • 10644283729 scopus 로고    scopus 로고
    • Serum concentrations of interleukin-8, vascular endothelial growth factor, and epidermal growth factor receptor in patients with squamous cell cancer of the head and neck
    • Gokhale AS, Haddad RI, Cavacini LA, et al. Serum concentrations of interleukin-8, vascular endothelial growth factor, and epidermal growth factor receptor in patients with squamous cell cancer of the head and neck. Oral Oncol 2005; 41: 70-76.
    • (2005) Oral Oncol , vol.41 , pp. 70-76
    • Gokhale, A.S.1    Haddad, R.I.2    Cavacini, L.A.3
  • 88
    • 77954756627 scopus 로고    scopus 로고
    • Expression of tumour-suppressing chemokine BRAK/CXCL14 reduces cell migration rate of HSC-3 tongue carcinoma cells and stimulates attachment to collagen and formation of elongated focal adhesions in vitro
    • Sato K, Ozawa S, Izukuri K, Kato Y, Hata R,. Expression of tumour-suppressing chemokine BRAK/CXCL14 reduces cell migration rate of HSC-3 tongue carcinoma cells and stimulates attachment to collagen and formation of elongated focal adhesions in vitro. Cell Biol Int 2010; 34: 513-522.
    • (2010) Cell Biol Int , vol.34 , pp. 513-522
    • Sato, K.1    Ozawa, S.2    Izukuri, K.3    Kato, Y.4    Hata, R.5
  • 89
    • 77954699174 scopus 로고    scopus 로고
    • Expression of a chemokine BRAK/CXCL14 in oral floor carcinoma cells reduces the settlement rate of the cells and suppresses their proliferation in vivo
    • Ito S, Ozawa S, Ikoma T, Yajima N, Kiyono T, Hata R,. Expression of a chemokine BRAK/CXCL14 in oral floor carcinoma cells reduces the settlement rate of the cells and suppresses their proliferation in vivo. Biomed Res 2010; 31: 199-206.
    • (2010) Biomed Res , vol.31 , pp. 199-206
    • Ito, S.1    Ozawa, S.2    Ikoma, T.3    Yajima, N.4    Kiyono, T.5    Hata, R.6
  • 90
    • 78149471244 scopus 로고    scopus 로고
    • Chemokine CXCL14/BRAK transgenic mice suppress growth of carcinoma cell transplants. [corrected]
    • Izukuri K, Suzuki K, Yajima N, et al. Chemokine CXCL14/BRAK transgenic mice suppress growth of carcinoma cell transplants. [corrected]. Transgenic Res 2010; 19: 1109-1117.
    • (2010) Transgenic Res , vol.19 , pp. 1109-1117
    • Izukuri, K.1    Suzuki, K.2    Yajima, N.3
  • 91
    • 16644396832 scopus 로고    scopus 로고
    • Chemokine receptors 6 and 7 identify a metastatic expression pattern in squamous cell carcinoma of the head and neck
    • Wang J, Xi L, Gooding W, Godfrey TE, Ferris RL,. Chemokine receptors 6 and 7 identify a metastatic expression pattern in squamous cell carcinoma of the head and neck. Adv Otorhinolaryngol 2005; 62: 121-133.
    • (2005) Adv Otorhinolaryngol , vol.62 , pp. 121-133
    • Wang, J.1    Xi, L.2    Gooding, W.3    Godfrey, T.E.4    Ferris, R.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.