Expression of CXCR4 and its down-regulation by IFN-γ in head and neck squamous cell carcinoma

Clinical Cancer Research

Volumn 11, Issue 8, 2005, Pages 2937-2946

  Katayama, Akihiro ^a   Ogino, Takeshi ^a   Bandoh, Nobuyuki ^a   Nonaka, Satoshi ^a   Harabuchi, Yasuaki ^a  

^a ASAHIKAWA MEDICAL COLLEGE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ANTINEOPLASTIC AGENT; CHEMOKINE RECEPTOR CXCR4; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 1BETA; MATRIGEL; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; STROMAL CELL DERIVED FACTOR 1; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ARTICLE; CANCER CHEMOTHERAPY; CANCER SURVIVAL; CELL MIGRATION; CELL PROLIFERATION; CHEMOTAXIS; CLINICAL FEATURE; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOKINE RELEASE; DOWN REGULATION; ENZYME PHOSPHORYLATION; FEMALE; FLOW CYTOMETRY; HEAD CANCER; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOLOGY; MALE; METASTASIS; MULTIVARIATE ANALYSIS; NECK CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SQUAMOUS CELL CARCINOMA; TUMOR BIOPSY; WESTERN BLOTTING;

ADULT; AGED; BLOTTING, WESTERN; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; DOWN-REGULATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HEAD AND NECK NEOPLASMS; HUMANS; IMMUNOHISTOCHEMISTRY; INTERFERON TYPE II; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; NEOPLASM STAGING; RECEPTORS, CXCR4; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SURVIVAL ANALYSIS;

EID: 17144413337     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-04-1470     Document Type: Article

References (44)

1. Wang JM, Deng X, Gong W, Su S. Chemokines and their role in tumor growth and metastasis. J Immunol Methods 1998;220:1-17.
2. Kim CH, Broxmeyer HE. SLC/exodus2/6Ckine/TCA4 induces chemotaxis of hematopoietic progenitor cells: differential activity of ligands of CCR7, CXCR3, or CXCR4 in chemotaxis vs. suppression of progenitor proliferation. J Leukoc Biol 1999;66:455-61.
3. Muller A, Homey B, Soto H, et al. Involvement of chemokine receptors in breast cancer metastasis. Nature 1999;410:50-6.
4. Scotton C, Milliken D, Wilson J, Raju S, Balkwill F. Analysis of CC chemokine and chemokine receptor expression in solid ovarian tumours. Br J Cancer 2001;85:891-7.
5. Phillips RJ, Burdick MD, Lutz M, Belperio JA, Keane MP, Strieter RM. The stromal derived factor-1/CXCL12-CXC chemokine receptor 4 biological axis in non-small cell lung cancer metastases. Am J Respir Crit Care Med 2003;167:1676-86.
6. Taichman RS, Cooper C, Keller ET, Pienta KJ, Taichman NS, McCauley LK. Use of the stromal cell-derived factor-1/CXCR4 pathway in prostate cancer metastasis to bone. Cancer Res 2002;62:1832-7.
7. Sun YX, Wang J, Shelburne CE, et al. Expression of CXCR4 and CXCL12 (SDF-1) in human prostate cancers (PCa) in vivo. J Cell Biochem 2003;89:462-73.
8. Koshiba T, Hosotani R, Miyamoto Y, et al. Expression of stromal cell-derived factor 1 and CXCR4 ligand receptor system in pancreatic cancer: a possible role for tumor progression. Clin Cancer Res 2000;6:3530-5.
9. Hwang JH, Chung HK, Kim DW, et al. CXC chemokine receptor 4 expression and function in human anaplastic thyroid cancer cells. J Clin Endocrinol Metab 2003;88:408-16.
10. Staller P, Sulitkova J, Lisztwan J, Moch H, Oakeley EJ, Krek W. Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL. Nature 2003;425:307-11.
11. Kijima T, Maulik G, Ma PC, et al. Regulation of cellular proliferation, cytoskeletal function, and signal transduction through CXCR4 and c-Kit in small cell lung cancer cells. Cancer Res 2002;62:6304-11.
12. Barbero S, Bonavia R, Bajetto A, et al. Stromal cell-derived factor 1α stimulates human glioblastoma cell growth through the activation of both extracellular signal-regulated kinases 1/2 and Akt. Cancer Res 2003;63:1969-74.
13. Nagase H, Miyamasu M, Yamaguchi M, et al. Cytokine-mediated regulation of CXCR4 expression in human neutrophils. J Leukoc Biol 2002;71:711-7.
14. Shirazi Y, Pitha PM. Interferon downregulates CXCR4 (fusin) gene expression in peripheral blood mononuclear cells. J Hum Virol 1998;1:69-76.
15. Gupta SK, Lysko PG, Pillarisetti K, Ohlstein E, Stadel JM. Chemokine receptors in human endothelial cells. Functional expression of CXCR4 and its transcriptional regulation by inflammatory cytokines. J Biol Chem 1998;273:4282-7.
16. Nagase H, Miyamasu M, Yamaguchi M, et al. Expression of CXCR4 in eosinophils: functional analyses and cytokine-mediated regulation. J Immunol 2000;164:5935-43.
17. Patterson BK, Czerniewski M, Andersson J, et al. Regulation of CCR5 and CXCR4 expression by type 1 and type 2 cytokines: CCR5 expression is downregulated by IL-10 in CD4-positive lymphocytes. Clin Immunol 1999;91:254-62.
18. Eddleston J, Christiansen SC, Zuraw BL. Functional expression of the C-X-C chemokine receptor CXCR4 by human bronchial epithelial cells: regulation by proinflammatory mediators. J Immunol 2002;169:6445-51.
19. Takahashi K, Kanazawa H, Akiyama Y, et al. Establishment and characterization of a cell line (SAS) from poorly differentiated human squamous cell carcinoma of the tongue. J Jpn Stomatol Soc 1989;38:20-8.
20. Miyauchi S, Moroyama T, Sakamoto T, Okamoto T, Takada K. Establishment of human tumor cell line (Ueda-1) derived from squamous cell carcinoma of the floor of the mouth. Jpn J Oral Maxillofac Surg 1985;31:1347-51.
21. Horikoshi M, Kimura Y, Nagura H, Ono T, Ito H. A new cell line derived from human carcinoma of the gingiva I. Its establishment and morphological studies. Jpn J Oral Surg 1974;2:100-6.
22. Wakamatsu Y, Nakayama K, Nakagawa K, et al. Influence of verapamil on effectiveness of cisplatin to the cell-line delivered from human squamous cell carcinoma. Nippon Univ Dent J 1991;65:1070-7.
23. Komiyama S, Matsui K, Miyazaki H, Kudoh S, Mizoguchi H, Shimizu N. Heterogeneity in epidermal growth factor responsiveness and tumor growth of human maxillary cancer cell lines. Ann Otol Rhinol Laryngol 1992;101:519-24.
24. Eura M, Chikamatsu K, Ogi K, Nakano K, Masuyama K, Ishikawa T. Expression of genes MAGE-1, -2, and -3 by human maxillary carcinoma cells. Anticancer Res 1995;15:55-9.
25. Bandoh N, Hayashi T, Kishibe K, et al. Prognostic value of p53 mutations, bax, and spontaneous apoptosis in maxillary sinus squamous cell carcinoma. Cancer 2002;94:1968-80.
26. Kato M, Kitayama J, Kazama S, Nagawa H. Expression pattern of CXC chemokine receptor-4 is correlated with lymph node metastasis in human invasive ductal carcinoma. Breast Cancer Res 2003;5:R144-50.
27. Lane WJ, Dias S, Hattori K, et al. Stromal-derived factor 1-induced megakaryocyte migration and platelet production is dependent on matrix metalloproteinases. Blood 2000;96:4152-9.
28. Libura J, Drukala J, Majka M, et al. CXCR4-SDF-1 signaling is active in rnabdomyosarcoma cells and regulates locomotion, chemotaxis, and adhesion. Blood 2002;100:2597-606.
29. Janowska-Wieczorek A, Marquez LA, Dobrowsky A, Ratajczak MZ, Cabuhat ML. Differential MMP and TIMP production by human marrow and peripheral blood CD34 (+) cells in response to chemokines. Exp Hematol 2000;28:1274-85.
30. Shirozu M, Nakano T, Inazawa J, et al. Structure and chromosomal localization of the human stromal cell-derived factor 1 (SDF1) gene. Genomics 1995;28:495-500.
31. Scotton CJ, Wilson JL, Scott K, et al. Multiple actions of the chemokine CXCL12 on epithelial tumor cells in human ovarian cancer. Cancer Res 2002;62:5930-8.
32. Begum NA, Shibuta K, Mori M, Barnard GF. Reduced expression of the CXCR4 receptor mRNA in hepatocellular carcinoma and lack of inducibility of its ligand α-chemokine hlRH/SDF1α/PBSF in vitro. Int J Oncol 1999;14:927-34.
33. Shibuta K, Begum NA, Mori M, Shimoda K, Akiyoshi T, Barnard GF. Reduced expression of the CXC chemokine hlRH/SDF-1α mRNA in hepatoma and digestive tract cancer. Int J Cancer 1997;73:656-62.
34. Spano JP, Andre F, Morat L, et al. Chemokine receptor CXCR4 and early-stage non-small cell lung cancer: pattern of expression and correlation with outcome. Ann Oncol 2004;15:613-7.
35. Uchida D, Begum NM, Almofti A, et al. Possible role of stromal-cell-derived factor-1/CXCR4 signaling on lymph node metastasis of oral squamous cell carcinoma. Exp Cell Res 2003;290:289-302.
36. Oh JW, Drabik K, Kutsch O, Choi C, Tousson A, Benveniste EN. CXC chemokine receptor 4 expression and function in human astroglioma cells. J Immunol 2001;166:2695-704.
37. Han Y, Wang J, He T, Ransohoff RM. TNF-α downregulates CXCR4 expression in primary murine astrocytes. Brain Res 2001;888:1-10.
38. Moriuchi M, Moriuchi H, Turner W, Fauci AS. Cloning and analysis of the promoter region of CXCR4, a coreceptor for HIV-1 entry. J Immunol 1997;159:4322-9.
39. Xie RL, Gupta S, Miele A, et al. The tumor suppressor interferon regulatory factor 1 interferes with SP1 activation to repress the human CDK2 promoter. J Biol Chem 2003;278:26589-96.
40. Mamane Y, Heylbroeck C, Genin P, et al. Interferon regulatory factors: the next generation. Gene 1999;237:1-14.
41. Cristillo AD, Highbarger HC, Dewar RL, Dimitrov DS, Golding H, Bierer BE. Up-regulation of HIV coreceptor CXCR4 expression in human T lymphocytes is mediated in part by a cAMP-responsive element. FASEB J 2002;16:354-64.
42. Odemis V, Moepps B, Gierschik P, Engele J. Interleukin-6 and cAMP induce stromal cell-derived factor-1 chemotaxis in astroglia by up-regulating CXCR4 cell surface expression. Implications for brain inflammation. J Biol Chem 2002;277:39801-8.
43. Gagliardi MC, De Magistris MT. Maturation of human dendritic cells induced by the adjuvant cholera toxin: role of cAMP on chemokine receptor expression. Vaccine 2003;21:856-61.
44. Christian M, Marangos P, Mak I, et al. Interferon-γ modulates prolactin and tissue factor expression in differentiating human endometrial stromal cells. Endocrinology 2001;142:3142-51.