Thrombin mediates migration of rat brain astrocytes via PLC, Ca 2+, CaMKII, PKCα, and AP-1-dependent matrix metalloproteinase-9 expression

Molecular Neurobiology

Volumn 48, Issue 3, 2013, Pages 616-630

  Lin, Chih Chung ^a   Lee, I Ta ^a   Wu, Wen Bin ^b   Liu, Chiung Ju ^c   Hsieh, Hsi Lung ^d   Hsiao, Li Der ^c   Yang, Chien Chung ^c   Yang, Chuen Mao ^c  

^a CHANG GUNG UNIVERSITY   (Taiwan)

^b FU JEN CATHOLIC UNIVERSITY   (Taiwan)

^c CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^d CHANG GUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

Author keywords

Astrocytes; Matrix metalloproteinase 9; Neurodegeneration; Signaling pathway; Thrombin

Indexed keywords

1 [N,O BIS(5 ISOQUINOLINESULFONYL) N METHYLTYROSYL] 4 PHENYLPIPERAZINE; 1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; GELATINASE B; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE 9; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN C FOS; PROTEIN C JUN; PROTEIN KINASE C ALPHA; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE 1; THROMBIN; TRICYCLO[4.3.0.1]DECAN 9 YL XANTHOGENATE;

ANIMAL CELL; ASTROCYTE; CALCIUM CELL LEVEL; CELL MIGRATION; CONTROLLED STUDY; NONHUMAN; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; ASTROCYTES; BRAIN; CALCIUM; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CALMODULIN; CELL MOVEMENT; CELLS, CULTURED; ENZYME PRECURSORS; MATRIX METALLOPROTEINASE 9; MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN BIOSYNTHESIS; PROTEIN KINASE C-ALPHA; RATS; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; THROMBIN; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION, GENETIC; TYPE C PHOSPHOLIPASES;

EID: 84888002850     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-013-8450-6     Document Type: Article

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