Thrombin induces MCP-1 expression through Rho-kinase and subsequent p38MAPK/NF-κB signaling pathway activation in vascular endothelial cells

Biochemical and Biophysical Research Communications

Volumn 411, Issue 4, 2011, Pages 798-803

  Kawanami, Daiji ^a   Matoba, Keiichiro ^a   Kanazawa, Yasushi ^a   Ishizawa, Sho ^a   Yokota, Tamotsu ^a   Utsunomiya, Kazunori ^a  

^a JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Atherosclerosis; Endothelial cells; Rho kinase; Thrombin

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; FASUDIL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; THROMBIN;

ANIMAL EXPERIMENT; AORTA; ARTICLE; CELL MIGRATION; CHEMOTAXIS; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENE EXPRESSION; HUMAN; HUMAN CELL; MALE; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; SIGNAL TRANSDUCTION; SUPERNATANT; VASCULAR ENDOTHELIUM;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; AMIDES; ANIMALS; AORTA; CELL MOVEMENT; CELLS, CULTURED; CHEMOKINE CCL2; ENDOTHELIUM, VASCULAR; GENE EXPRESSION; HUMANS; MICE; MICE, INBRED STRAINS; MONOCYTES; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN KINASE INHIBITORS; PYRIDINES; RHO-ASSOCIATED KINASES; THROMBIN;

MUS;

EID: 80051557245     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.07.031     Document Type: Article

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