Thrombin activation of PI3K/PDK1/Akt signaling promotes cyclin D1 upregulation and RPE cell proliferation

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1813, Issue 10, 2011, Pages 1758-1766

  Parrales, A ^a   Lopez E ^a   Lopez Colome A M ^a  

^a INSTITUTO DE FISIOLOGÍA CELULAR   (Mexico)

Author keywords

Akt; Cyclin D1; Proliferation; Thrombin

Indexed keywords

CYCLIN D1; G PROTEIN COUPLED RECEPTOR; GLYCOGEN SYNTHASE KINASE 3BETA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; THROMBIN; VISUAL PIGMENT;

ARTICLE; CELL PROLIFERATION; HUMAN; HUMAN CELL; MOLECULAR MECHANICS; NUCLEAR EXPORT SIGNAL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; UPREGULATION; VITREORETINOPATHY;

ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; CYCLIN D1; MODELS, BIOLOGICAL; ONCOGENE PROTEIN V-AKT; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RATS; RATS, LONG-EVANS; RETINAL PIGMENT EPITHELIUM; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; THROMBIN; UP-REGULATION;

EID: 80051795873     PISSN: 01674889     EISSN: 18792596     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2011.06.009     Document Type: Article

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