Biosynthesis of chloro-β-hydroxytyrosine, a nonproteinogenic amino acid of the peptidic backbone of glycopeptide antibiotics

Journal of Bacteriology

Volumn 186, Issue 18, 2004, Pages 6093-6100

  Puk, Oliver ^a,c   Bischoff, Daniel ^b,d   Kittel, Claudia ^a   Pelzer, Stefan ^a,e   Weist, Stefan ^b   Stegmann, Efthimia ^a   Süssmuth, Roderich D ^b   Wohlleben, Wolfgang ^a,b  

^a Mikrobiologisches Institut   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

^d B Ingelheim Pharma GmbH/Co KG   (Germany)

^e MerLion Pharmaceuticals GmbH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; ANTIBIOTIC AGENT; BALHIMYCIN; CHLORO BETA HYDROXYTYROSINE; CHLOROEREMOMYCIN; CYTOCHROME P450; CYTOCHROME P450 MONOOXYGENASE OXYD; GLYCOPEPTIDE; HYDROLASE; NONRIBOSOMAL PEPTIDE SYNTHETASE D; OXYGENASE; PEPTIDE SYNTHASE; PERHYDROLASE; PHENYLGLYCINE; RNA DIRECTED DNA POLYMERASE; TYROSINE DERIVATIVE; UNCLASSIFIED DRUG; VANCOMYCIN;

ACTINOBACTERIA; AMINO ACID SYNTHESIS; AMYCOLATOPSIS BALHIMYCINA; ANTIBIOTIC BIOSYNTHESIS; ARTICLE; BACTERIAL GENE; BACTERIUM MUTANT; BHP GENE; BPSD GENE; CHLORINATION; CONTROLLED STUDY; CULTURE MEDIUM; ELECTROSPRAY MASS SPECTROMETRY; GENE DELETION; GENE INACTIVATION; GENETIC COMPLEMENTATION; LIQUID CHROMATOGRAPHY; NONHUMAN; NUCLEOTIDE SEQUENCE; OPERON; OXYD GENE; PEPTIDE SYNTHESIS; PRIORITY JOURNAL;

ACTINOMYCETALES; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; CYTOCHROME P-450 ENZYME SYSTEM; DIHYDROXYPHENYLALANINE; DNA, BACTERIAL; GENE DELETION; GENES, BACTERIAL; GENETIC COMPLEMENTATION TEST; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; OPERON; PEPTIDE SYNTHASES; SEQUENCE ANALYSIS, DNA; VANCOMYCIN;

ACTINOBACTERIA (CLASS); AMYCOLATOPSIS; AMYCOLATOPSIS BALHIMYCINA; BACTERIA (MICROORGANISMS); UNCULTURED ACTINOMYCETE;

EID: 4444240578     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.186.18.6093-6100.2004     Document Type: Article

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