Crystal structure of OxyB, a cytochrome P450 implicated in an oxidative phenol coupling reaction during vancomycin biosynthesis

Journal of Biological Chemistry

Volumn 277, Issue 49, 2002, Pages 47476-47485

  Zerbe, Katja ^a   Pylypenko, Olena ^b,c   Vitali, Francesca ^a   Zhang, Weiwen ^a   Rouset, Severine ^a   Heck, Markus ^a   Vrijbloed, Jan W ^a   Bischoff, Daniel ^d   Bister, Bojan ^d   Süssmuth, Roderich D ^d   Pelzer, Stefan ^d   Wohlleben, Wolfgang ^d   Robinson, John A ^a   Schlichting, Ilme ^b,c  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

^c MAX PLANCK INSTITUTE FOR MEDICAL RESEARCH   (Germany)

^d UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTICS; CATALYSIS; CLONING; CRYSTAL STRUCTURE; ESCHERICHIA COLI; GENES; IRON; OXIDATION; PHENOLS; REDUCTION;

COUPLING REACTION;

BIOSYNTHESIS;

CYTOCHROME P450; DITHIONITE; FERREDOXIN; PROTEIN OXYB; UNCLASSIFIED DRUG; VANCOMYCIN;

ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVE SITE; GENE INACTIVATION; GENE SEQUENCE; MOLECULAR CLONING; MOLECULAR SIZE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FOLDING; STRUCTURE ANALYSIS; TURNOVER TIME; ULTRAVIOLET RADIATION;

ACTINOMYCETALES; AMINO ACID SEQUENCE; ASPARAGINE; BINDING SITES; CLONING, MOLECULAR; CRYSTALLOGRAPHY, X-RAY; ELECTRONS; ESCHERICHIA COLI; FERREDOXIN-NADP REDUCTASE; FERREDOXINS; GENE LIBRARY; GENETIC VECTORS; HYDROGEN-ION CONCENTRATION; MODELS, CHEMICAL; MODELS, GENETIC; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; OXYGEN; PEPTIDES; PHENOL; PROTEIN BINDING; RECEPTORS, STEROID; SEQUENCE ANALYSIS, DNA; SPECTROPHOTOMETRY; ULTRAVIOLET RAYS; VANCOMYCIN; X-RAYS;

AMYCOLATOPSIS ORIENTALIS; ESCHERICHIA COLI; SPINACIA OLERACEA;

EID: 0347298786     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M206342200     Document Type: Article

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