Crystal Structure of OxyC, a Cytochrome P450 Implicated in an Oxidative C-C Coupling Reaction during Vancomycin Biosynthesis

Journal of Biological Chemistry

Volumn 278, Issue 47, 2003, Pages 46727-46733

  Pylypenko, Olena ^a,b   Vitali, Francesca ^c   Zerbe, Katja ^c   Robinson, John A ^c   Schlichting, Ilme ^a,b  

^a MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

^b MAX PLANCK INSTITUTE FOR MEDICAL RESEARCH   (Germany)

^c UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTICS; BIOSYNTHESIS; CATALYSIS; CRYSTAL STRUCTURE; CYTOLOGY; POLYPEPTIDES; SPECTRUM ANALYSIS; ULTRAVIOLET RADIATION;

LIGANDS; OXIDATIVE COUPLING;

BIOCHEMISTRY;

CARRIER PROTEIN; CYTOCHROME P450; HEMOPROTEIN; IRON DERIVATIVE; PEPTIDE DERIVATIVE; THIOESTER; VANCOMYCIN;

AMINO ACID SEQUENCE; ARTICLE; CHEMICAL REACTION; COUPLING REACTION; CRYSTAL STRUCTURE; CRYSTALLIZATION; DRUG SYNTHESIS; ENZYME ACTIVE SITE; ENZYME SUBSTRATE; ESCHERICHIA COLI; MOLECULAR BIOLOGY; NONHUMAN; OXIDATION; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN FUNCTION; STRUCTURE ANALYSIS; ULTRAVIOLET SPECTROSCOPY;

ACTINOMYCETALES; BACTERIAL PROTEINS; BINDING SITES; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; CYTOCHROME P-450 ENZYME SYSTEM; ELECTRON TRANSPORT; IRON; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; SPECTRUM ANALYSIS; VANCOMYCIN; WATER;

AMYCOLATOPSIS; AMYCOLATOPSIS ORIENTALIS; ESCHERICHIA COLI;

EID: 0345306647     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M306486200     Document Type: Article

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