Cloning and analysis of a peptide synthetase gene of the balhimycin producer Amycolatopsis mediterranei DSM5908 and development of a gene disruption/replacement system

Journal of Biotechnology

Volumn 56, Issue 2, 1997, Pages 115-128

  Pelzer, Stefan ^a   Reichert, Wolfgang ^a   Huppert, Michaela ^a   Heckmann, Dorothée ^a   Wohlleben, Wolfgang ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Amycolatopsis mediterranei; Direct transformation; Gene disruption gene replacement; Glycopeptide antibiotic; Peptide synthetase

Indexed keywords

AMINO ACIDS; ANTIBIOTICS; BIOSYNTHESIS; CELL CULTURE; COLIFORM BACTERIA; DNA SEQUENCES; ENZYMES; FUNGI; GENES;

AMYCOLATOPSIS MEDITERRANEI; ESCHERICHIA COLI; GENE REPLACEMENT SYSTEM; GLYCOPEPTIDE ANTIBIOTICS; PEPTIDE SYNTHETASE;

CLONING;

ANTIBIOTIC AGENT; BALHIMYCIN; GLYCOPEPTIDE; UNCLASSIFIED DRUG;

ACTINOBACTERIA; ARTICLE; DRUG SYNTHESIS; GENE DISRUPTION; GENE EXPRESSION; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL;

ACTINOBACTERIA; AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BASE SEQUENCE; BLOTTING, SOUTHERN; CLONING, MOLECULAR; ESCHERICHIA COLI; GENES, BACTERIAL; MOLECULAR SEQUENCE DATA; PEPTIDE SYNTHASES; PLASMIDS; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; TRANSFECTION; TRANSFORMATION, GENETIC; VANCOMYCIN;

ACTINOBACTERIA (CLASS); AMYCOLATOPSIS MEDITERRANEI; ESCHERICHIA; ESCHERICHIA COLI; FUNGI;

EID: 0343376474     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-1656(97)00082-5     Document Type: Article

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