Preservation of hepatic phenotype in lentiviral-transduced primary human hepatocytes

Chemico-Biological Interactions

Volumn 173, Issue 3, 2008, Pages 179-186

  Zamule, Stephanie M ^a   Strom, Stephen C ^b   Omiecinski, Curtis J ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

CAR; Differentiation; Lentivirus; Primary human hepatocytes; siRNA

Indexed keywords

CYTOCHROME P450 2B6; GREEN FLUORESCENT PROTEIN; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; LENTIVIRUS VECTOR; NUCLEAR FACTOR; NUCLEAR FACTOR CAR; NUCLEAR FACTOR HNF4 ALPHA; NUCLEAR FACTOR PXR; NUCLEAR FACTOR PXR ALPHA;

ADULT; AGED; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL LINE; CELL THERAPY; CONTROLLED STUDY; FEMALE; GENE OVEREXPRESSION; GENOMICS; HUMAN; HUMAN CELL; LIVER CELL; LIVER DYSFUNCTION; MALE; MODULATION; PHENOTYPE; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSITIVITY ANALYSIS; TOXICOLOGY;

ADULT; AGED; ARYL HYDROCARBON HYDROXYLASES; BASE SEQUENCE; CELL LINE; CELLS, CULTURED; CYTOCHROME P-450 CYP3A; FEMALE; GENE EXPRESSION REGULATION; GENETIC VECTORS; HEPATOCYTE NUCLEAR FACTOR 4; HEPATOCYTES; HUMANS; LENTIVIRUS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; OXIDOREDUCTASES, N-DEMETHYLATING; PHENOTYPE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, STEROID; RETINOID X RECEPTOR ALPHA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; SERUM ALBUMIN; TRANSCRIPTION FACTORS; TRANSDUCTION, GENETIC;

LENTIVIRUS;

EID: 44349133270     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2008.03.015     Document Type: Article

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