Lead exposure results in hearing loss and disruption of the cochlear blood-labyrinth barrier and the protective role of iron supplement

NeuroToxicology

Volumn 39, Issue , 2013, Pages 173-181

  Liu, Xinqin ^a   Zheng, Gang ^a   Wu, Yongxiang ^a   Shen, Xuefeng ^a   Jing, Jinfei ^a   Yu, Tao ^a   Song, Han ^a   Chen, Jingyuan ^a   Luo, Wenjing ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Blood labyrinth barrier; Hearing loss; Lead; Outer hair cells; Tight junction proteins

Indexed keywords

CLAUDIN 5; IRON; LEAD; OCCLUDIN; PROTEIN ZO1; TIGHT JUNCTION PROTEIN;

ACOUSTIC NERVE FIBER; ANIMAL EXPERIMENT; ARTICLE; AUDITORY SYSTEM; BASILAR MEMBRANE; COCHLEA BLOOD FLOW; CONTROLLED STUDY; DOWN REGULATION; ENDOTHELIUM CELL; EVOKED AUDITORY RESPONSE; GUINEA PIG; HAIR CELL; HEARING IMPAIRMENT; HEAVY METAL POISONING; IMMUNOFLUORESCENCE; INNER EAR; IRON THERAPY; MALE; MOLECULAR MECHANICS; NONHUMAN; PERMEABILITY BARRIER; PRIORITY JOURNAL; RAT; STRIA VASCULARIS;

CAVIA; RATTUS;

ABR; AUDITORY NERVE-BRAINSTEM EVOKED RESPONSES; BBB; BCB; BLB; BLOOD-BRAIN BARRIER; BLOOD-CEREBROSPINAL FLUID BARRIER; BLOOD-LABYRINTH BARRIER; HEARING LOSS; IHC; LEAD; OHCS; OUTER HAIR CELLS; SINNER HAIR CELLS; TEM; TIGHT JUNCTION PROTEINS; TJPS; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; ANIMALS, NEWBORN; CLAUDINS; COCHLEA; DIETARY SUPPLEMENTS; DISEASE MODELS, ANIMAL; DOWN-REGULATION; ELECTROENCEPHALOGRAPHY; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; GUINEA PIGS; HAIR CELLS, AUDITORY; HEARING LOSS; MALE; MICROSCOPY, ELECTRON, TRANSMISSION; OCCLUDIN; ORGANOMETALLIC COMPOUNDS; RATS; RATS, SPRAGUE-DAWLEY; ZONULA OCCLUDENS-1 PROTEIN;

EID: 84887537139     PISSN: 0161813X     EISSN: 18729711     Source Type: Journal    
DOI: 10.1016/j.neuro.2013.10.002     Document Type: Article

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