The role of toxicokinetics in xylene-induced ototoxicity in the rat and guinea pig

Toxicology

Volumn 231, Issue 2-3, 2007, Pages 147-158

  Gagnaire, F ^a   Marignac, B ^a   Blachere V ^a   Grossmann, S ^a   Langlais, C ^a  

^a INSTITUT NATIONAL DE RECHERCHE ET DE SÉCURITÉ   (France)

Author keywords

Guinea pig; Ototoxicity; Rat; Toxicokinetics; Xylene

Indexed keywords

META XYLENE; PARA XYLENE; SOLVENT; XYLENE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; BRAIN LEVEL; COCHLEA; GUINEA PIG; HAIR CELL; HEARING LOSS; HISTOPATHOLOGY; MALE; NONHUMAN; OTOTOXICITY; PRIORITY JOURNAL; RAT; SPECIES DIFFERENCE; SPRAGUE DAWLEY RAT; TOXICOKINETICS;

ANIMALS; COCHLEA; DOSE-RESPONSE RELATIONSHIP, DRUG; HAIR CELLS, INNER; HAIR CELLS, OUTER; INHALATION EXPOSURE; ISOMERISM; MALE; RATS; RATS, SPRAGUE-DAWLEY; SOLVENTS; STRUCTURE-ACTIVITY RELATIONSHIP; XYLENES;

CAVIA; RATTUS;

EID: 33847111647     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2006.11.075     Document Type: Article

References (46)

1. Backes W.L., Sequeira D.J., Cawley G.F., and Eyer C.S. Relationship between hydrocarbon structure and induction of P450: effects on protein levels and enzyme activities. Xenobiotica 23 (1993) 1353-1366
2. Benignus V.A., Muller K.E., Barton C.N., and Bittikofer J.A. Toluene levels in blood and brain of rats during and after respiratory exposure. Toxicol. Appl. Pharmacol. 61 (1981) 326-334
3. Campo P., Lataye R., and Bonnet P. No interaction between noise and toluene on cochlea in the guinea pig. Acta Acoust. 1 (1993) 35-42
4. Campo P., Lataye R., Cossec B., and Placidi V. Toluene-induced hearing loss: a mid-frequency location of the cochlear lesions. Neurotoxicol. Teratol. 19 (1997) 129-140
5. Campo P., Loquet G., Blachere V., and Roure M. Toluene and styrene intoxication route in the rat cochlea. Neurotoxicol. Teratol. 21 (1999) 427-434
6. Campo P., Blachère V., Payan J.-P., Pouyatos B., and Lataye R. Toxicokinetic parameters of toluene in the rat and guinea pig: a comparative study. Environ. Toxicol. Pharmacol. 19 (2005) 555-559
7. Campo P., Blachère V., Payan J.-P., Cossec B., and Ducos P. Toluene toxicokinetics and metabolism parameters in the rat and guinea pig. Environ. Toxicol. Pharmacol. 21 (2006) 276-282
8. Cappaert N.L.M., Klis S.F., Muijser H., de Groot J.C.J., Kulig B.M., and Smoorenburg G. The ototoxic effects of ethyl benzene in rats. Hear. Res. 137 (1999) 91-102
9. Cappaert N.L., Klis S.F., Baretta A.B., Muijser H., and Smoorenburg G.F. Ethyl benzene-induced ototoxicity in rats: a dose-dependent mid-frequency hearing loss. J. Assoc. Res. Otolaryngol. 1 (2000) 292-299
10. Cappaert N.L., Klis S.F.L., Muijser H., Kulig B.M., and Smoorenburg G.F. Simultaneous exposure to ethyl benzene and noise: synergistic effects on outer cells. Hear. Res. 162 (2001) 67-79
11. Cappaert N.L.M., Klis S.F.L., Muijser H., Kulig B.M., Ravensberg L.C., and Smoorenburg G.F. Differential susceptibility of rats and guinea pigs to the toxic effects of ethyl benzene. Neurotoxicol. Teratol. 24 (2002) 503-510
12. Carpenter C.P., Kinkead E.R., Geary D.L., Sullivan L.J., and King J.M. Petroleum hydrocarbon toxicity studies. V. Animal and human response to vapors of mixed xylenes. Toxicol. Appl. Pharmacol. 33 (1975) 543-558
13. Crofton K.M., Lassiter T.L., and Rebert C.S. Solvent-induced ototoxicity in rats: an atypical selective mid-frequency hearing deficit. Hear. Res. 80 (1994) 25-30
14. Davis R.R., Murphy W.J., Snawder J.E., Striley C.A., Henderson D., Khan A., and Krieg E.F. Susceptibility to the ototoxic properties of toluene is species specific. Hear. Res. 166 (2002) 24-32
15. Elovaara E. Dose-related effects of meta-xylene inhalation on the xenobiotic metabolism of the rat. Xenobiotica 12 (1982) 345-352
16. European Centre for Ecotoxicology and Toxicology (ECETOC), 1986. Joint Assessment of Commodity Chemicals No. 6: Xylenes. ECETOC, Brussels, Belgium, pp. 1-61.
17. Fay M., Eisenmann C., Diwan S., and de Rosa C. ATSDR evaluation of health effects of chemicals. V. Xylenes: health effects, toxicokinetics, human exposure, and environmental fate. Toxicol. Ind. Health 14 (1998) 571-781
18. Fechter L.D. Effects of acute styrene and simultaneous noise exposure on auditory function in the guinea pig. Neurotoxicol. Teratol. 15 (1993) 151-155
19. Gagnaire F., Marignac B., Langlais C., and Bonnet P. Ototoxicity in rats exposed to ortho-, meta- and para-xylene vapours for 13 weeks. Pharmacol. Toxicol. 89 (2001) 6-14
20. Gagnaire F., and Langlais C. Relative ototoxicity of 21 aromatic solvents. Arch. Toxicol. 79 (2005) 346-354
21. Gagnaire F., Langlais C., Grossmann S., and Wild P. Ototoxicity in rats exposed to ethylbenzene and to two technical xylene vapours for 13 weeks. Arch. Toxicol. 81 (2007) 127-143
22. Gut I., Terelius Y., Frantik E., Linhart I., Soucek P., Filipcova B., and Kluckova H. Exposure to various benzene derivatives differently induces cytochromes P450 2B1 and P450 2E1 in rat liver. Arch. Toxicol. 67 (1993) 237-243
23. Johnson A.-C., and Canlon B. Progressive hair cell loss induced by toluene exposure. Hear. Res. 75 (1994) 201-208
24. Kim S.K., and Kim Y.C. Effect of a single administration of benzene, toluene or meta-xylene on carboxyhaemoglobin elevation and metabolism of dichloromethane in rats. J. Appl. Toxicol. 16 (1996) 437-444
25. Lataye R., Campo P., Pouyatos B., Cossec B., Blachere V., and Morel G. Solvent ototoxicity in the rat and guinea pig. Neurotoxicol. Teratol. 25 (2003) 39-50
26. Lautermann J., Crann S.A., McLaren J., and Schacht J. Glutathione-dependent antioxidant systems in the mammalian inner ear: effects of aging, ototoxic drugs and noise. Hear. Res. 114 (1997) 75-82
27. Low L.K., Meeks J.R., and Mackerer C.R. Health effects of the alkylbenzenes. II. Xylenes. Toxicol. Ind. Health 5 (1989) 85-105
28. Nakajima T. Cytochrome P450 isoforms and the metabolism of volatile hydrocarbons of low relative molecular mass. J. Occup. Health 39 (1997) 83-91
29. Pathiratne A., Puyear R.L., and Brammer J.D. A comparative study of the effects of benzene, toluene, and xylenes on their in vitro metabolism and drug-metabolizing enzymes in rat liver. Toxicol. Appl. Pharmacol. 82 (1986) 272-280
30. Pryor G.T., Dickinson J., Howd R.A., and Rebert C.S. Neurobehavioral effects of subchronic exposure of weanling rats to toluene or hexane. Neurobehav. Toxicol. Teratol. 5 (1983) 47-52
31. Pryor G.T., Dickinson J., Feeney E., and Rebert C.S. Hearing loss in rats exposed to toluene as weanlings or as young adults. Neurobehav. Toxicol. Teratol. 6 (1984) 111-119
32. Pryor G.T., Rebert C.S., and Howd R.A. Hearing loss in rats caused by inhalation of mixed xylenes and styrene. J. Appl. Toxicol. 7 (1987) 55-61
33. Pryor G., Rebert C., Kassay K., Kuiper H., and Gordon R. The hearing loss associated with exposure to toluene is not caused by a metabolite. Brain Res. Bull. 27 (1991) 109-113
34. Pryor G.T. Assessment of auditory dysfunction. In: Chang L.W. (Ed). Principles of Neurotoxicology (1994), Marcel Dekker, New York 345-371
35. Raunio H., Liira J., Elovaara E., Riihimaki V., and Pelkonen O. Cytochrome P450 isozyme induction by methyl ethyl ketone and meta-xylene in rat liver. Toxicol. Appl. Pharmacol. 103 (1990) 175-179
36. Rebert C.S., Sorenson S.S., Howd R.A., and Pryor G.T. Toluene induced hearing loss in rats evidenced by the brainstem auditory-evoked response. Neurobehav. Toxicol. Teratol. 5 (1983) 59-62
37. SRI International, 1994. Directory of Chemical Producers. Menlo Park, CA, USA, pp. 997-998.
38. Sullivan M.J., Rarey K.E., and Conolly R.B. Ototoxicity of toluene in rats. Neurotoxicol. Teratol. 10 (1988) 525-530
39. Tassaneeyakul W., Birkett D.J., Edwards J.W., Veronese M.E., Tassaneeyakul W., Tukey R.H., and Miners J.O. Human cytochrome P450 isoform specificity in the regioselective metabolism of toluene and o-, m- and para-xylene. J. Pharmacol. Exp. Ther. 276 (1996) 101-108
40. Toftgard R., Nilsen O.G., and Gustafsson J.A. Changes in rat liver microsomal cytochrome P-450 and enzymatic activities after the inhalation of n-hexane, xylene, methyl ethyl ketone and methylchloroform for four weeks. Scand. J. Work Environ. Health 7 (1981) 31-37
41. Toftgard R., and Nilsen O.G. Effects of xylene isomers on cytochrome P-450 and in vitro enzymatic activities in rat liver, kidney and lung. Toxicology 23 (1982) 197-212
42. Toftgard R., Halpert J., and Gustafsson J.A. Xylene induces a cytochrome P-450 isozyme in rat liver similar to the major isozyme induced by phenobarbital. Mol. Pharmacol. 23 (1983) 265-271
43. Toftgard R., Nilsen O.G., Glaumann H., and Gustafsson J.A. Induction of cytochrome P-450 in the rat liver after exposure to xylenes, dose-response relationship and dependence on endocrine factors. Toxicology 27 (1983) 119-137
44. US Environmental Protection Agency (US EPA), 2003. Toxicological Review of Xylenes. EPA 635/R-03/001.
45. Yano B.L., Dittenber D.A., Albee R.R., and Mattsson J.L. Abnormal auditory brainstem responses and cochlear pathology in rats induced by an exaggerated styrene exposure regimen. Toxicol. Pathol. 20 (1992) 1-6
46. Yuan W., White T.B., White J.W., Strobel H.W., and Backes W.L. Relationship between hydrocarbon structure and induction of P450: effect on RNA levels. Xenobiotica 25 (1995) 9-16