Neurophysiologic and neurocognitive case profiles of andean patients with chronic environmental lead poisoning

Journal of Toxicology and Environmental Health - Part A: Current Issues

Volumn 72, Issue 19, 2009, Pages 1150-1159

  Counter, S Allen ^a,b   Buchanan, Leo H ^c,d   Ortega, Fernando ^e  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c UNIVERSITY OF MASSACHUSETTS   (United States)

^d HARVARD UNIVERSITY   (United States)

^e UNIVERSIDAD SAN FRANCISCO DE QUITO   (Ecuador)

Author keywords

[No Author keywords available]

Indexed keywords

ENVIRONMENTAL CHEMICAL; LEAD;

ADOLESCENT; ADULT; ARTICLE; AUDITORY MEMORY; AUDITORY NERVOUS SYSTEM; BRAIN STEM; CASE REPORT; CERAMIC INDUSTRY; CHELATION; CHELATION THERAPY; CLINICAL ASSESSMENT; COCHLEA; COGNITION; ELECTROPHYSIOLOGY; EVOKED BRAIN STEM AUDITORY RESPONSE; FAMILY COUNSELING; FEMALE; HUMAN; LEAD BLOOD LEVEL; LEAD POISONING; LEARNING DISORDER; LONG TERM EXPOSURE; MALE; NEUROLOGIC DISEASE; NEUROPHYSIOLOGY; OCCUPATIONAL EXPOSURE; OCCUPATIONAL HAZARD; OTOACOUSTIC EMISSION; PERIPHERAL NERVOUS SYSTEM; PRIORITY JOURNAL; RISK ASSESSMENT; SOMATOSENSORY CORTEX; VISUAL SYSTEM;

ADOLESCENT; CERAMICS; CHELATION THERAPY; CHILD; CHRONIC DISEASE; ECUADOR; ENVIRONMENTAL POLLUTANTS; FEMALE; HEARING; HUMANS; LEAD POISONING, NERVOUS SYSTEM, CHILDHOOD; MALE; SUCCIMER;

EID: 75149169713     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/15287390903091772     Document Type: Article

References (53)

1. Banks, E. C., Ferretti, L. E., and Shucard, D. W. 1997. Effects of low level lead exposure on cognitive function in children: A review of behavioral, neuropsychological and biological evidence. Neurotoxicology 18:237-282.
2. Bellinger, D. 1996. Learning and behavioral sequelae of lead poisoning. In Lead poisoning in childhood, eds. S. M. Pueschel, J. G. Linakis, and A. C. Anderson, pp. 97- 115. Baltimore, MD: Paul H. Brookes Publishing.
3. Benetou-Marantidou, A., Nakou, S., and Mich-eloyannis, J. 1988. Neurobehavioral estimation of children with life-long increased lead exposure. Arch. Environ. Health 43:392-395.
4. Bleecker, M. L., Ford, D. P, Lingren, K. N., Hoese, V. M., Walsh, K. S., and Vaughan, C. G. 2005. Differential effects of lead exposure on components of verbal memory. Occup. Environ. Med. 62:181-187.
5. Bleecker, M. L., Ford, D. P., Lindgren, K. N., Scheetz, K., and Tiburzi, M. J. 2003 Association of chronic and current measures of lead exposure with different components of brainstem auditory evoked potentials. Neurotoxicology 24:625-631.
6. Bouton, C. M., Frelin, L. P., Forde, C. E., Arnold-Godwin, H., and Pevsner, J. 2001. Synaptotagmin I is a molecular target for lead. J. Neurochem. 76:1724-1735.
7. Buchanan, L. H., Counter, S. A., Ortega, F., and Laurell, G. 1999. Distortion product oto-acoustic emissions in Andean children and adults with chronic lead intoxication. Acta Otolaryngol. 119:652-658.
8. Canfield, R. L., Kreher, D. A., Cornwell, C., and Henderson, C. R., Jr. 2003a. Low-level lead exposure, executive functioning, and learning in early childhood. Child. Neuropsychol. 9:35-53.
9. Canfield, R. L., Henderson, C. R., Cory-Slechta, D. A., Cox, C., Jusko, T. A., and Lanphear, B. P. 2003b. Intellectual impairment in children with blood lead concentrations below 10 ?g per deciliter. N. Engl. J. Med. 348:1517-1526.
10. Centers for Disease Control and Prevention. 1991. Preventing lead poisoning in young children: A statement by the U.S. Department of Health and Human Services. Atlanta, GA: CDC. U.S. Government Printing Office (No.537), October.
11. Counter, S. A. 2002. Brainstem neural conduction biomarkers in leadexposed children of Andean lead-glaze workers. J. Occup. Environ. Med. 44:855-864.
12. Counter, S. A., and Buchanan, L. H. 2002. Neuro-ototoxicity in Andean adults with chronic lead and noise exposure. J. Occup. Environ. Med. 44:30-38.
13. Counter, S. A., Buchanan, L. H., and Ortega, F. 2004. Current pediatric and maternal lead levels in blood and breast milk in Andean inhabitants of a lead-glazing enclave. J. Occup. Environ. Med. 46:967-973.
14. Counter, S. A., Buchanan, L. H., and Ortega, F. 2007a. Lead concentrations in maternal blood and breast milk and pediatric blood of Andean villagers: 2006 Follow-up investigation. J. Occup. Environ. Med. 49:302-309.
15. Counter, S. A., Buchanan, L. H., and Ortega, F. 2005. Neurocognitive impairment in lead-exposed children of Andean lead-glazing workers. J. Occup. Environ. Med. 47:306-312.
16. Counter, S. A., Buchanan, L. H., Ortega, F., Amarisiriwardena, C., and Hu, H. 2000. Environmental lead contamination and pediatric lead intoxication in an Ecuadorian Andean village. Int. J. Occup. Environ. Health 6:169-176.
17. Counter, S. A., Buchanan, L. H., Laurell, G., and Ortega, F. 1998a. Field screening of blood lead levels in remote Andean villages. Neurotoxicology 19:871-878.
18. Counter, S. A., Buchanan, L. H., Ortega, F., and Laurell, G. 1997a. Normal auditory brainstem and cochlear function in extreme pediatric plumbism. J. Neurol. Sci. 152:85-92.
19. Counter, S. A., Buchanan, L. H., Ortega, F., Rifai, N., and Shannon, M. W. 2007b. Comparative analysis of zinc protoporphyrin and blood lead levels in lead-exposed Andean children. Clin. Biochem. 40:787-792.
20. Counter, S. A., Buchanan, L. H., Rosas, H. D., and Ortega, F. 1998b. Neurocognitive effects of chronic lead intoxication in Andean children. J. Neurol. Sci. 160:47-53.
21. Counter, S. A., Ortega, F., Shannon, M. W., and Buchanan, L. H. 2003. Succimer (meso-2,3-dimercaptosuccinic acid (DMSA) treatment of Andean children with environmental lead exposure. Int. J. Occup. Environ. Health 9:164-168.
22. Counter, S. A, Vather, M., Laurell, G., Buchanan, L. H., Ortega, F., and Skerfving, S. 1997b. High lead exposure and auditory sensory-neural function in Andean children. Environ. Health Perspect. 105:522-526.
23. David, O.J., Hoffman, P., Sverd, J., Clark, J., and Voeller, K. 1976. Lead and hyperactivity. Behavioral response to chelation: A pilot study. Am. J. Psychiat. 133:1155-1158.
24. De Gennaro, L. D. 2002. Lead and the developing nervous system. Growth Dev. Aging 66:43-50.
25. Dietrich, K. N., Succop, P. A., Bornschein, R. L., Krafft, K. M., Berger, O., Hammond, P. B., and Buncher, C. R. 1990. Lead exposure and neurobehavioral development in later infancy. Environ. Health Perspect. 89:13-19.
26. Dietrich, K. N., Ware, J. H., Salganik, M., Radcliffe, J., Rogan, W. J., Rhoads, G. G., Fay, M. E., Davoli, C. T., Denckla, M. B., Bornschein, R. L., Schwarz, D., Dockery, D. W., Adubato, S., and Jones, R. L. 2004. Treatment of leadexposed children clinical trial group. Effect of chelation therapy on the neuropsychological and behavioral development of lead-exposed children after school entry. Pediatrics 114:19-26.
27. Dudek, B., and Merecz, D. 1997. Impairment of psychological functions in children environmentally exposed to lead. Int. J. Occup. Med. Environ. Health 10:37-46.
28. Harari, R., and Cullen, M. R. 1995. Childhood lead intoxication associated with manufacture of roof tiles and ceramics in the Ecuadorian Andes. Arch. Environ Health 50:393.
29. Harcourt Assessment, Inc. 2005. Escala de Inteligencia de Wechsler para Niños- IV (WISC-IV). Madrid: Impreso en España. Edita: TEA Ediciones, S.A.
30. Holdstein, Y., Pratt, H., Goldsher, M., Rosen, G., Shenhav, R., Linn, S., Mor, A., and Barkai, A. 1986. Auditory brainstem evoked potentials in asymptomatic lead-exposed subjects. J. Laryngol. Otol. 100:1031-1036.
31. Kaul, B., and Mukerjee, H. 1999. Elevated blood lead and erythrocyte protoporphyrin levels of children near a battery-recycling plant in Haina, Dominican Republic. Int. J. Occup. Environ. Health 5:307-312.
32. Kaul, B., Sandhu, R. S., Depratt, C., and Reyes, F. 1999. Follow-up screening of lead-poisoned children near an auto battery recycling plant, Haina, Dominican Republic. Environ. Health Perspect. 107:917-920.
33. Lalor, G. C., Vutchkov, M. K., Bryan, S. T., Christie, C. D., Donaldson, D., Young, J., and Chambers, S. 2006. Acute lead poisoning associated with backyard lead smelting in Jamaica. West Indian Med. J. 55:394-398.
34. Lalor, G., Vutchkov, M., and Bryan, S. 2007. Blood lead levels of Jamaican children island-wide. Sci. Total Environ. 374: 235-241.
35. Lanphear, B. P., Dietrich, K., Auinger, P., and Cox, C. 2000. Cognitive deficits associated with blood lead concentrations 10 microg/dL in US children and adolescents. Public Health Rep 115: 521-529.
36. Lanphear, B. P., Hornung, R., Khoury, J., Yolton, K., Baghurst, P., Bellinger, D. C., Canfield, R. L., Dietrich, K. N., Bornschein, R., Greene, T., Rothenberg, S. J., Needleman, H. L., Schnaas, L., Wasserman, G., Graziano, J., and Roberts, R. 2005. Low-level environmental lead exposure and children's intellectual function: An international pooled analysis. Environ. Health Perspect. 113:894-899.
37. Lidsky, T. I., and Schneider, J. S. 2003. Lead neurotoxicity in children: Basic mechanisms and clinical correlates. Brain 126:5-19.
38. Liu, X., Dietrich, K. N., Radcliffe, J., Ragan, N. B., Rhoads, G. G., and Rogan, W. J. 2002. Do children with falling blood lead levels have improved cognition? Pediatrics 110:787-791.
39. Manor, E., and Freundlich, E. 1983. Lead poisoning from ceramics in the Arab population. Arch. Toxicol. Suppl. 6:275-278.
40. Matte, T. D., Figueroa, J. P., Burr, G., Flesch, J. P., Keenlyside, R. A., and Baker, E. L. 1989. Lead exposure among lead-acid battery workers in Jamaica. Am. J. Ind. Med. 16:167-177.
41. National Research Council. 1993. Measuring lead exposure in infants, children, and other sensitive populations. Washington, DC: National Academy Press.
42. Needleman, H. L., Gunnoe, C., Leviton, A., Reed, R., Peresie, H., Maher, C., and Barrett, P. 1979. Deficits in psychologic and classroom performance of children with elevated dentin lead levels. N. Engl. J. Med. 300:689-695.
43. Raven, J., Raven, J. C., and Court, J. H. 1998. Manual for Raven's Progressive Matrices and Vocabulary Scales: Section 2 Coloured Progressive Matrices. London: Oxford Psychologists Press.
44. Rogan, W. J., Dietrich, K. N., Ware, J. H., Dockery, D. W., Salganik, M., Radcliffe, J., Jones, R. L., Ragan, N. B., Chisolm, J. J., Jr., and Rhoads, G. G. 2001. Treatment of lead-exposed children trial. The effect of chelation therapy with succimer on neuropsychological development in children exposed to lead. N. Engl. J. Med. 344:1421-1426.
45. Rothenberg, S. J., Poblano, A., and Garza-Morales, S. 1994. Prenatal and perinatal low-level lead exposure alters brainstem auditory evoked responses in infants. Neurotoxicology 15:695-700.
46. Ruff, H. A., Bijur, P. E., Markowitz, M. E., Ma, Y. C., and Rosen, J. F. 1993. Declining blood lead levels and cognitive changes in moderately leadpoisoned children. J. Am. Med. Assoc. 269:1641-1646.
47. Schwartz, J., and Otto, D. 1987. Blood lead, hearing thresholds and neurobehavioral development in children and youth. Arch. Environ. Health 42: 153-160.
48. Schwartz, J., and Otto, D. 1991. Lead and minor hearing impairment. Arch. Environ. Health 46:300-305.
49. Shannon, M. W. 1998. Lead. In Clinical management of poisoning and drug overdose, 3rd ed., eds. L. M. Haddad, M. W. Shannon, and J. F. Winchester, pp. 767-783. Philadelphia: W. B. Saunders.
50. Sizemore, O. J., and Amler, R. W. 1996. Characteristics of ATSDR's adult and pediatric environmental neurobehavioral test batteries. Neurotoxicology 17:229-236.
51. Surkan, P. J., Zhang, A., Trachtenberg, F., Daniel, D. B., McKinlay, S., and Bellinger, D. C. 2007. Neurophyschological function in children with blood lead levels 10 ?g/dl. Neurotoxicology 28: 1170 -1177.
52. Trepka, M. J., Pekovic, V., Santana, J. C., and Zhang, G. 2005. Risk factors for lead poisoning among Cuban refugee children. Public Health Rep. 120: 179-185.
53. Zou, C., Zhao, Z., Tang, L., Chen, Z., and Du. L. 2003. The effect of lead on brainstem auditory evoked potentials in children. Chin. Med. J. 116:565-568.