Na+/K+-ATPase α1 identified as an abundant protein in the blood-labyrinth barrier that plays an essential role in the barrier integrity

PLoS ONE

Volumn 6, Issue 1, 2011, Pages

  Yang, Yue ^a   Dai, Min ^a   Wilson, Teresa M ^a   Omelchenko, Irina ^a   Klimek, John E ^b   Wilmarth, Phillip A ^b   David, Larry L ^b   Nuttall, Alfred L ^a,c,d   Gillespie, Peter G ^a,b   Shi, Xiaorui ^a,d,e  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^d SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^e Chinese Academy of Medical Sciences   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM) ALPHA1; OCCLUDIN; PROTEIN KINASE C ETA; UNCLASSIFIED DRUG; ATP1A1 PROTEIN, MOUSE; MEMBRANE PROTEIN; PROTEIN KINASE C;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLOOD LABYRINTH BARRIER; COCHLEA; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FEMALE; MALE; MASS SPECTROMETRY; MOUSE; NONHUMAN; PERMEABILITY BARRIER; PROTEIN ANALYSIS; PROTEIN DATABASE; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN ISOLATION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEOMICS; SIGNAL TRANSDUCTION; STRIA VASCULARIS; ANIMAL; CAPILLARY; ENZYMOLOGY; INNER EAR; METABOLISM; METHODOLOGY; PHYSIOLOGY; VASCULARIZATION;

ANIMALS; CAPILLARIES; DATABASES, PROTEIN; EAR, INNER; MASS SPECTROMETRY; MEMBRANE PROTEINS; MICE; PROTEIN KINASE C; PROTEOMICS; SODIUM-POTASSIUM-EXCHANGING ATPASE;

EID: 79551626442     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0016547     Document Type: Article

References (55)

1. Juhn SK, Hunter BA, Odland RM (2001) Blood-labyrinth barrier and fluid dynamics of the inner ear. Int Tinnitus J 7: 72-83.
2. Juhn SK, Rybak LP (1981) Labyrinthine barriers and cochlear homeostasis. Acta Otolaryngol 91: 529-534.
3. Lin DW, Trune DR (1997) Breakdown of stria vascularis blood-labyrinth barrier in C3H/lpr autoimmune disease mice. Otolaryngol Head Neck Surg 117: 530-534.
4. Doi K, Mori N, Matsunaga T (1992) Adenylate cyclase modulation of ion permeability in the guinea pig cochlea: a possible mechanism for the formation of endolymphatic hydrops. Acta Otolaryngol 112: 667-673.
5. Klein M, Koedel U, Kastenbauer S, Pfister HW (2008) Nitrogen and oxygen molecules in meningitis-associated labyrinthitis and hearing impairment. Infection 36: 2-14.
6. Cohen-Salmon M, Regnault B, Cayet N, Caille D, Demuth K, et al. (2007) Connexin30 deficiency causes instrastrial fluid-blood barrier disruption within the cochlear stria vascularis. Proc Natl Acad Sci U S A 104: 6229-6234.
7. Suzuki M, Yamasoba T, Ishibashi T, Miller JM, Kaga K (2002) Effect of noise exposure on blood-labyrinth barrier in guinea pigs. Hear Res 164: 12-18.
8. Calabria AR, Shusta EV (2006) Blood-brain barrier genomics and proteomics: elucidating phenotype, identifying disease targets and enabling brain drug delivery. Drug Discov Today 11: 792-799.
9. Pottiez G, Flahaut C, Cecchelli R, Karamanos Y (2009) Understanding the blood-brain barrier using gene and protein expression profiling technologies. Brain Res Rev 62: 83-98.
10. Motoyama A, Yates JR, 3rd (2008) Multidimensional LC separations in shotgun proteomics. Anal Chem 80: 7187-7193.
11. Geering K (2008) Functional roles of Na,K-ATPase subunits. Curr Opin Nephrol Hypertens 17: 526-532.
12. Skou JC, Esmann M (1992) The Na,K-ATPase. J Bioenerg Biomembr 24: 249-261.
13. Skou JC (2004) The Identification of the Sodium Pump. Biosci Rep 24: 436-451.
14. Violette MI, Madan P, Watson AJ (2006) Na+/K+ -ATPase regulates tight junction formation and function during mouse preimplantation development. Dev Biol 289: 406-419.
15. Wilmarth PA, Riviere MA, David LL (2009) Techniques for accurate protein identification in shotgun proteomic studies of human, mouse, bovine, and chicken lenses. J Ocul Biol Dis Infor 2: 223-234.
16. Shi X (2009) Cochlear pericyte responses to acoustic trauma and the involvement of hypoxia-inducible factor-1alpha and vascular endothelial growth factor. Am J Pathol 174: 1692-1704.
17. Osada S, Mizuno K, Saido TC, Akita Y, Suzuki K, et al. (1990) A phorbol ester receptor/protein kinase, nPKC eta, a new member of the protein kinase C family predominantly expressed in lung and skin. J Biol Chem 265: 22434-22440.
18. Suzuki T, Elias BC, Seth A, Shen L, Turner JR, et al. (2009) PKC eta regulates occludin phosphorylation and epithelial tight junction integrity. Proc Natl Acad Sci U S A 106: 61-66.
19. Takeuchi S, Ando M, Sato T, Kakigi A (2001) Three-dimensional and ultrastructural relationships between intermediate cells and capillaries in the gerbil stria vascularis. Hear Res 155: 103-112.
20. Liu H, Sadygov RG, Yates JR, 3rd (2004) A model for random sampling and estimation of relative protein abundance in shotgun proteomics. Anal Chem 76: 4193-4201.
21. Rajasekaran AK, Gopal J, Rajasekaran SA (2003) Na,K-ATPase in the regulation of epithelial cell structure. Ann N Y Acad Sci 986: 649-651.
22. Rajasekaran SA, Barwe SP, Gopal J, Ryazantsev S, Schneeberger EE, et al. (2007) Na-K-ATPase regulates tight junction permeability through occludin phosphorylation in pancreatic epithelial cells. Am J Physiol Gastrointest Liver Physiol 292: G124-133.
23. Musch MW, Walsh-Reitz MM, Chang EB (2006) Roles of ZO-1, occludin, and actin in oxidant-induced barrier disruption. Am J Physiol Gastrointest Liver Physiol 290: G222-231.
24. Huber JD, Egleton RD, Davis TP (2001) Molecular physiology and pathophysiology of tight junctions in the blood-brain barrier. Trends Neurosci 24: 719-725.
25. Harhaj NS, Antonetti DA (2004) Regulation of tight junctions and loss of barrier function in pathophysiology. Int J Biochem Cell Biol 36: 1206-1237.
26. Stuart RO, Nigam SK (1995) Regulated assembly of tight junctions by protein kinase C. Proc Natl Acad Sci U S A 92: 6072-6076.
27. Seth A, Sheth P, Elias BC, Rao R (2007) Protein phosphatases 2A and 1 interact with occludin and negatively regulate the assembly of tight junctions in the CACO-2 cell monolayer. J Biol Chem 282: 11487-11498.
28. Munoz DJ, Kendrick IS, Rassam M, Thorne PR (2001) Vesicular storage of adenosine triphosphate in the guinea-pig cochlear lateral wall and concentrations of ATP in the endolymph during sound exposure and hypoxia. Acta Otolaryngol 121: 10-15.
29. Gratton MA, Smyth BJ, Schulte BA, Vincent DA, Jr. (1995) Na,K-ATPase activity decreases in the cochlear lateral wall of quiet-aged gerbils. Hear Res 83: 43-50.
30. Rajasekaran SA, Palmer LG, Moon SY, Peralta Soler A, Apodaca GL, et al. (2001) Na,K-ATPase activity is required for formation of tight junctions, desmosomes, and induction of polarity in epithelial cells. Mol Biol Cell 12: 3717-3732.
31. Durr E, Yu J, Krasinska KM, Carver LA, Yates JR, et al. (2004) Direct proteomic mapping of the lung microvascular endothelial cell surface in vivo and in cell culture. Nat Biotechnol 22: 985-992.
32. Stockwin LH, Blonder J, Bumke MA, Lucas DA, Chan KC, et al. (2006) Proteomic analysis of plasma membrane from hypoxia-adapted malignant melanoma. J Proteome Res 5: 2996-3007.
33. Eisenberg HM, Suddith RL (1979) Cerebral vessels have the capacity to transport sodium and potassium. Science 206: 1083-1085.
34. Shull GE, Schwartz A, Lingrel JB (1985) Amino-acid sequence of the catalytic subunit of the (Na+ + K+)ATPase deduced from a complementary DNA. Nature 316: 691-695.
35. Shull GE, Lane LK, Lingrel JB (1986) Amino-acid sequence of the beta-subunit of the (Na+ + K+)ATPase deduced from a cDNA. Nature 321: 429-431.
36. Morth JP, Pedersen BP, Toustrup-Jensen MS, Sorensen TL, Petersen J, et al. (2007) Crystal structure of the sodium-potassium pump. Nature 450: 1043-1049.
37. Xie Z (2003) Molecular mechanisms of Na/K-ATPase-mediated signal transduction. Ann N Y Acad Sci 986: 497-503.
38. Betz WJ, Caldwell JH, Ribchester RR, Robinson KR, Stump RF (1980) Endogenous electric field around muscle fibres depends on the Na+-K+ pump. Nature 287: 235-237.
39. Cornelius F, Mahmmoud YA (2009) Interaction between cardiotonic steroids and Na,K-ATPase. Effects of pH and ouabain-induced changes in enzyme conformation. Biochemistry 48: 10056-10065.
40. Chen YH, Lu Q, Goodenough DA, Jeansonne B (2002) Nonreceptor tyrosine kinase c-Yes interacts with occludin during tight junction formation in canine kidney epithelial cells. Mol Biol Cell 13: 1227-1237.
41. Tian J, Cai T, Yuan Z, Wang H, Liu L, et al. (2006) Binding of Src to Na+/K+- ATPase forms a functional signaling complex. Mol Biol Cell 17: 317-326.
42. Hirose K, Liberman MC (2003) Lateral wall histopathology and endocochlear potential in the noise-damaged mouse cochlea. J Assoc Res Otolaryngol 4: 339-352.
43. Ohlemiller KK (2008) Recent findings and emerging questions in cochlear noise injury. Hear Res 245: 5-17.
44. Clifford RE, Rogers RA (2009) Impulse noise: theoretical solutions to the quandary of cochlear protection. Ann Otol Rhinol Laryngol 118: 417-427.
45. Liberman MC, Kiang NY (1978) Acoustic trauma in cats. Cochlear pathology and auditory-nerve activity. Acta Otolaryngol Suppl 358: 1-63.
46. Gratton MA, Schulte BA (1995) Alterations in microvasculature are associated with atrophy of the stria vascularis in quiet-aged gerbils. Hear Res 82: 44-52.
47. Lamm K, Arnold W (1996) Noise-induced cochlear hypoxia is intensity dependent, correlates with hearing loss and precedes reduction of cochlear blood flow. Audiol Neurootol 1: 148-160.
48. Nuttall AL (1999) Sound-Induced Cochlear Ischemia/Hypoxia as a Mechanism of Hearing Loss. Noise Health 2: 17-32.
49. Santi PA, Duvall AJ, 3rd (1978) Stria vascularis pathology and recovery following noise exposure. Otolaryngology 86: ORL354-361.
50. Minami SB, Yamashita D, Ogawa K, Schacht J, Miller JM (2007) Creatine and tempol attenuate noise-induced hearing loss. Brain Res 1148: 83-89.
51. Le Prell CG, Hughes LF, Miller JM (2007) Free radical scavengers vitamins A, C, and E plus magnesium reduce noise trauma. Free Radic Biol Med 42: 1454-1463.
52. Fechter LD, Gearhart C, Fulton S, Campbell J, Fisher J, et al. (2007) JP-8 jet fuel can promote auditory impairment resulting from subsequent noise exposure in rats. Toxicol Sci 98: 510-525.
53. McFadden SL, Ohlemiller KK, Ding D, Shero M, Salvi RJ (2001) The influence of superoxide dismutase and glutathione peroxidase deficiencies on noiseinduced hearing loss in mice. Noise Health 3: 49-64.
54. Hsu CJ, Shau WY, Chen YS, Liu TC, Lin-Shiau SY (2000) Activities of Na(+),K(+)-ATPase and Ca(2+)-ATPase in cochlear lateral wall after acoustic trauma. Hear Res 142: 203-211.
55. Muto S, Nemoto J, Okada K, Miyata Y, Kawakami K, et al. (2000) Intracellular Na+ directly modulates Na+,K+-ATPase gene expression in normal rat kidney epithelial cells. Kidney Int 57: 1617-1635.