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Volumn 9, Issue 11, 2013, Pages 1801-1817

The TOMM machinery is a molecular switch in PINK1 and PARK2/PARKIN- dependent mitochondrial clearance

Author keywords

Mitochondria; Mitophagy; Outer mitochondrial membrane; PARK2; Parkinson disease; PINK1; TOMM machinery

Indexed keywords

CARRIER PROTEIN; MITOCHONDRIAL PROTEIN; PARKIN; PARKINSON PROTEIN 2; PTEN INDUCED PUTATIVE KINASE 1; TRANSLOCASE OF OUTER MITOCHONDRIAL MEMBRANE 40; UNCLASSIFIED DRUG;

EID: 84887488527     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.25884     Document Type: Article
Times cited : (109)

References (43)
  • 1
    • 80054787664 scopus 로고    scopus 로고
    • What genetics tells us about the causes and mechanisms of Parkinson's disease
    • PMID: 22013209
    • Corti O, Lesage S, Brice A. What genetics tells us about the causes and mechanisms of Parkinson's disease. Physiol Rev 2011; 91: 1161-218; PMID: 22013209; http://dx.doi.org/10.1152/physrev.00022.2010
    • (2011) Physiol Rev , vol.91 , pp. 1161-1218
    • Corti, O.1    Lesage, S.2    Brice, A.3
  • 2
    • 33745589773 scopus 로고    scopus 로고
    • Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin
    • DOI 10.1038/nature04779, PII N04779
    • Clark IE, Dodson MW, Jiang C, Cao JH, Huh JR, Seol JH, Yoo SJ, Hay BA, Guo M. Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin. Nature 2006; 441: 1162-6; PMID: 16672981; http://dx.doi.org/10.1038/nature04779 (Pubitemid 43990738)
    • (2006) Nature , vol.441 , Issue.7097 , pp. 1162-1166
    • Clark, I.E.1    Dodson, M.W.2    Jiang, C.3    Cao, J.H.4    Huh, J.R.5    Seol, J.H.6    Yoo, S.J.7    Hay, B.A.8    Guo, M.9
  • 3
    • 33745602748 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin
    • DOI 10.1038/nature04788, PII N04788
    • Park J, Lee SB, Lee S, Kim Y, Song S, Kim S, Bae E, Kim J, Shong M, Kim JM, et al. Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin. Nature 2006; 441: 1157-61; PMID: 16672980; http://dx.doi.org/10. 1038/nature04788 (Pubitemid 43990737)
    • (2006) Nature , vol.441 , Issue.7097 , pp. 1157-1161
    • Park, J.1    Lee, S.B.2    Lee, S.3    Kim, Y.4    Song, S.5    Kim, S.6    Bae, E.7    Kim, J.8    Shong, M.9    Kim, J.-M.10    Chung, J.11
  • 5
    • 55749090654 scopus 로고    scopus 로고
    • The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila
    • PMID: 18799731
    • Deng H, Dodson MW, Huang H, Guo M. The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila. Proc Natl Acad Sci U S A 2008; 105: 14503-8; PMID: 18799731; http://dx.doi.org/10.1073/pnas.0803998105
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 14503-14508
    • Deng, H.1    Dodson, M.W.2    Huang, H.3    Guo, M.4
  • 8
    • 58149314211 scopus 로고    scopus 로고
    • Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
    • PMID: 19029340
    • Narendra D, Tanaka A, Suen DF, Youle RJ. Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J Cell Biol 2008; 183: 795-803; PMID: 19029340; http://dx.doi.org/10.1083/jcb.200809125
    • (2008) J Cell Biol , vol.183 , pp. 795-803
    • Narendra, D.1    Tanaka, A.2    Suen, D.F.3    Youle, R.J.4
  • 9
    • 77951181836 scopus 로고    scopus 로고
    • PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
    • PMID: 20404107
    • Matsuda N, Sato S, Shiba K, Okatsu K, Saisho K, Gautier CA, Sou YS, Saiki S, Kawajiri S, Sato F, et al. PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy. J Cell Biol 2010; 189: 211-21; PMID: 20404107; http://dx.doi.org/10. 1083/jcb.200910140
    • (2010) J Cell Biol , vol.189 , pp. 211-221
    • Matsuda, N.1    Sato, S.2    Shiba, K.3    Okatsu, K.4    Saisho, K.5    Gautier, C.A.6    Sou, Y.S.7    Saiki, S.8    Kawajiri, S.9    Sato, F.10
  • 13
    • 78650467974 scopus 로고    scopus 로고
    • Mechanisms of mitophagy
    • PMID: 21179058
    • Youle RJ, Narendra DP. Mechanisms of mitophagy. Nat Rev Mol Cell Biol 2011; 12: 9-14; PMID: 21179058; http://dx.doi.org/10.1038/nrm3028
    • (2011) Nat Rev Mol Cell Biol , vol.12 , pp. 9-14
    • Youle, R.J.1    Narendra, D.P.2
  • 14
    • 78650729600 scopus 로고    scopus 로고
    • Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
    • PMID 2117 3115
    • Tanaka A, Cleland MM, Xu S, Narendra DP, Suen DF, Karbowski M, Youle RJ. Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin. J Cell Biol 2010; 191: 1367-80; PMID: 2117 3115; http://dx.doi.org/10. 1083/jcb.201007013
    • (2010) J Cell Biol , vol.191 , pp. 1367-1380
    • Tanaka, A.1    Cleland, M.M.2    Xu, S.3    Narendra, D.P.4    Suen, D.F.5    Karbowski, M.6    Youle, R.J.7
  • 15
  • 16
    • 79957472437 scopus 로고    scopus 로고
    • Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane
    • PMID: 21454557
    • Yoshii SR, Kishi C, Ishihara N, Mizushima N. Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane. J Biol Chem 2011; 286: 19630-40; PMID: 21454557; http://dx.doi.org/10. 1074/jbc.M110.209338
    • (2011) J Biol Chem , vol.286 , pp. 19630-19640
    • Yoshii, S.R.1    Kishi, C.2    Ishihara, N.3    Mizushima, N.4
  • 17
    • 68749112707 scopus 로고    scopus 로고
    • Importing mitochondrial proteins: Machineries and mechanisms
    • PMID: 19703392
    • Chacinska A, Koehler CM, Milenkovic D, Lithgow T, Pfanner N. Importing mitochondrial proteins: machineries and mechanisms. Cell 2009; 138: 628-44; PMID: 19703392; http://dx.doi.org/10.1016/j. cell.2009.08.005
    • (2009) Cell , vol.138 , pp. 628-644
    • Chacinska, A.1    Koehler, C.M.2    Milenkovic, D.3    Lithgow, T.4    Pfanner, N.5
  • 18
    • 84857032953 scopus 로고    scopus 로고
    • Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase Parkin
    • PMID: 22280891
    • Lazarou M, Jin SM, Kane LA, Youle RJ. Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase Parkin. Dev Cell 2012; 22: 320-33; PMID: 22280891; http://dx.doi.org/10.1016/j. devcel.2011.12.014
    • (2012) Dev Cell , vol.22 , pp. 320-333
    • Lazarou, M.1    Jin, S.M.2    Kane, L.A.3    Youle, R.J.4
  • 19
    • 36549006049 scopus 로고    scopus 로고
    • Importance of the lon protease in mitochondrial maintenance and the significance of declining lon in aging
    • DOI 10.1196/annals.1404.015, Molecular Mechanisms of Aging
    • Ngo JK, Davies KJ. Importance of the lon protease in mitochondrial maintenance and the significance of declining lon in aging. Ann N Y Acad Sci 2007; 1119: 78-87; PMID: 18056957; http://dx.doi.org/10.1196/annals.1404.015 (Pubitemid 350191233)
    • (2007) Annals of the New York Academy of Sciences , vol.1119 , Issue.1 , pp. 78-87
    • Ngo, J.K.1    Davies, K.J.A.2
  • 20
    • 0028049082 scopus 로고
    • PIM1 encodes a mitochondrial ATP-dependent protease that is required for mitochondrial function in the yeast Saccharomyces cerevisiae
    • Van D yck L, Pearce DA, Sherman F. PIM1 encodes a mitochondrial ATP-dependent protease that is required for mitochondrial function in the yeast Saccharomyces cerevisiae. J Biol Chem 1994; 269: 238-42; PMID: 8276800 (Pubitemid 24026650)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.1 , pp. 238-242
    • Van Dyck, L.1    Pearce, D.A.2    Sherman, F.3
  • 21
  • 22
    • 0030871088 scopus 로고    scopus 로고
    • Functional cooperation of the mitochondrial processing peptidase subunits
    • DOI 10.1006/jmbi.1997.1231
    • Luciano P, Geoffroy S, Brandt A, Hernandez JF, Géli V. Functional cooperation of the mitochondrial processing peptidase subunits. J Mol Biol 1997; 272: 213-25; PMID: 9299349; http://dx.doi.org/10.1006/jmbi.1997.1231 (Pubitemid 27397346)
    • (1997) Journal of Molecular Biology , vol.272 , Issue.2 , pp. 213-225
    • Luciano, P.1    Geoffroy, S.2    Brandt, A.3    Hernandez, J.-F.4    Geli, V.5
  • 25
    • 0033615958 scopus 로고    scopus 로고
    • The TOM core complex: The general protein import pore of the outer membrane of mitochondria
    • PMID: 10579717
    • Ahting U, Thun C, Hegerl R, Ty p k e D, Nargang FE, Neupert W, Nussberger S. The TOM core complex: the general protein import pore of the outer membrane of mitochondria. J Cell Biol 1999; 147: 959-68; PMID: 10579717; http://dx.doi.org/10.1083/jcb.147.5.959
    • (1999) J Cell Biol , vol.147 , pp. 959-968
    • Ahting, U.1    Thun, C.2    Hegerl, R.3    Typke, D.4    Nargang, F.E.5    Neupert, W.6    Nussberger, S.7
  • 26
    • 0032511189 scopus 로고    scopus 로고
    • The preprotein translocation channel of the outer membrane of mitochondria
    • DOI 10.1016/S0092-8674(00)81206-4
    • Künkele KP, Heins S, Dembowski M, Nargang FE, Benz R, Thieffry M, Walz J, Lill R, Nussberger S, Neupert W. The preprotein translocation channel of the outer membrane of mitochondria. Cell 1998; 93: 1009-19; PMID: 9635430; http://dx.doi.org/10.1016/S0092-8674(00)81206-4 (Pubitemid 28280794)
    • (1998) Cell , vol.93 , Issue.6 , pp. 1009-1019
    • Kunkele, K.-P.1    Heins, S.2    Dembowski, M.3    Nargang, F.E.4    Benz, R.5    Thieffry, M.6    Walz, J.7    Lill, R.8    Nussberger, S.9    Neupert, W.10
  • 27
    • 43249119207 scopus 로고    scopus 로고
    • Rational design and evaluation of FRET experiments to measure protein proximities in cells
    • Chapter 17:Unit 179
    • Snapp EL, Hegde RS. Rational design and evaluation of FRET experiments to measure protein proximities in cells. Curr Protoc Cell Biol 2006; Chapter 17:Unit 17 9
    • (2006) Curr Protoc Cell Biol
    • Snapp, E.L.1    Hegde, R.S.2
  • 29
    • 78649300971 scopus 로고    scopus 로고
    • P62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both
    • PMID: 20890124
    • Narendra D, Kane LA, Hauser DN, Fearnley IM, Youle RJ. p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both. Autophagy 2010; 6: 1090-106; PMID: 20890124; http://dx.doi.org/10.4161/auto.6.8.13426
    • (2010) Autophagy , vol.6 , pp. 1090-1106
    • Narendra, D.1    Kane, L.A.2    Hauser, D.N.3    Fearnley, I.M.4    Youle, R.J.5
  • 31
    • 84870013071 scopus 로고    scopus 로고
    • Voltage-dependent anion channels (VDACs) recruit Parkin to defective mitochondria to promote mitochondrial autophagy
    • PMID: 23060438
    • Sun Y, Vashisht AA, Tc h i e u J, Wohlschlegel JA, Dreier L. Voltage-dependent anion channels (VDACs) recruit Parkin to defective mitochondria to promote mitochondrial autophagy. J Biol Chem 2012; 287: 40652-60; PMID: 23060438; http://dx.doi.org/10.1074/jbc.M112.419721
    • (2012) J Biol Chem , vol.287 , pp. 40652-40660
    • Sun, Y.1    Vashisht, A.A.2    Tchieu, J.3    Wohlschlegel, J.A.4    Dreier, L.5
  • 33
    • 78649685455 scopus 로고    scopus 로고
    • Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL
    • PMID 211158 03
    • Jin SM, Lazarou M, Wang C, Kane LA, Narendra DP, Youle RJ. Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL. J Cell Biol 2010; 191: 933-42; PMID: 211158 03; http://dx.doi.org/10.1083/ jcb.201008084
    • (2010) J Cell Biol , vol.191 , pp. 933-942
    • Jin, S.M.1    Lazarou, M.2    Wang, C.3    Kane, L.A.4    Narendra, D.P.5    Youle, R.J.6
  • 34
    • 84868384387 scopus 로고    scopus 로고
    • Mitochondrial hexokinase HKI is a novel substrate of the Parkin ubiquitin ligase
    • PMID: 23068103
    • Okatsu K, Iemura S, Koyano F, Go E, Kimura M, Natsume T, Tanaka K, Matsuda N. Mitochondrial hexokinase HKI is a novel substrate of the Parkin ubiquitin ligase. Biochem Biophys Res Commun 2012; 428: 197-202; PMID: 23068103; http://dx.doi.org/10.1016/j.bbrc.2012.10.041
    • (2012) Biochem Biophys Res Commun , vol.428 , pp. 197-202
    • Okatsu, K.1    Iemura, S.2    Koyano, F.3    Go, E.4    Kimura, M.5    Natsume, T.6    Tanaka, K.7    Matsuda, N.8
  • 35
    • 84876296881 scopus 로고    scopus 로고
    • Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
    • PMID: 23503661
    • Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW. Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Nature 2013; 496: 372-6; PMID: 23503661; http://dx.doi.org/10.1038/nature12043
    • (2013) Nature , vol.496 , pp. 372-376
    • Sarraf, S.A.1    Raman, M.2    Guarani-Pereira, V.3    Sowa, M.E.4    Huttlin, E.L.5    Gygi, S.P.6    Harper, J.W.7
  • 36
    • 58549084167 scopus 로고    scopus 로고
    • Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes
    • PMID 19074260
    • Kim PK, Hailey DW, Mullen RT, Lippincott-Schwartz J. Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes. Proc Natl Acad Sci U S A 2008; 105: 20567-74; PMID: 19 074260; http://dx.doi.org/10.1073/pnas. 0810611105
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 20567-20574
    • Kim, P.K.1    Hailey, D.W.2    Mullen, R.T.3    Lippincott-Schwartz, J.4
  • 37
    • 0030613796 scopus 로고    scopus 로고
    • Bcl-x(L) regulates the membrane potential and volume homeostasis of mitochondria
    • Vander Heiden MG, Chandel NS, Williamson EK, Schumacker PT, Thompson CB. Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria. Cell 1997; 91: 627-37; PMID: 9393856; http://dx.doi.org/10.1016/S0092-8674(00) 80450-X (Pubitemid 27513654)
    • (1997) Cell , vol.91 , Issue.5 , pp. 627-637
    • Vander Heiden, M.G.1    Chandel, N.S.2    Williamson, E.K.3    Schumacker, P.T.4    Thompson, C.B.5
  • 38
    • 33745950626 scopus 로고    scopus 로고
    • Mitochondrial outer membrane permeabilization during apoptosis: The innocent bystander scenario
    • DOI 10.1038/sj.cdd.4401963, PII 4401963
    • Chipuk JE, Bouchier-Hayes L, Green DR. Mitochondrial outer membrane permeabilization during apoptosis: the innocent bystander scenario. Cell Death Differ 2006; 13: 1396-402; PMID: 16710362; http://dx.doi.org/10.1038/sj.c d d. 4 4 019 63 (Pubitemid 44057475)
    • (2006) Cell Death and Differentiation , vol.13 , Issue.8 , pp. 1396-1402
    • Chipuk, J.E.1    Bouchier-Hayes, L.2    Green, D.R.3
  • 39
    • 84879138893 scopus 로고    scopus 로고
    • Selective escape of proteins from the mitochondria during mitophagy
    • PMID: 23361001
    • Saita S, Shirane M, Nakayama KI. Selective escape of proteins from the mitochondria during mitophagy. Nat Commun 2013; 4: 1410; PMID: 23361001; http://dx.doi.org/10.1038/ncomms2400
    • (2013) Nat Commun , vol.4 , pp. 1410
    • Saita, S.1    Shirane, M.2    Nakayama, K.I.3
  • 40
    • 84861091750 scopus 로고    scopus 로고
    • Promising genetic biomarkers of preclinical Alzheimer's disease: The influence of APOE and TOMM40 on brain integrity
    • PMID: 22550605
    • Ferencz B, Karlsson S, Kalpouzos G. Promising genetic biomarkers of preclinical Alzheimer's disease: the influence of APOE and TOMM40 on brain integrity. Int J Alzheimers Dis 2012; 2012: 421452; PMID: 22550605; http://dx.doi.org/10.1155/2012/421452
    • (2012) Int J Alzheimers Dis , vol.2012 , pp. 421452
    • Ferencz, B.1    Karlsson, S.2    Kalpouzos, G.3
  • 41
    • 78650503526 scopus 로고    scopus 로고
    • ALS-linked mutant superoxide dismutase 1 (SOD1) alters mitochondrial protein composition and decreases protein import
    • PMID: 21078990
    • Li Q, Vande Velde C, Israelson A, Xie J, Bailey AO, Dong MQ, Chun SJ, Roy T, Winer L, Yates JR, et al. ALS-linked mutant superoxide dismutase 1 (SOD1) alters mitochondrial protein composition and decreases protein import. Proc Natl Acad Sci U S A 2010; 107: 21146-51; PMID: 21078990; http://dx.doi.org/10.1073/ pnas.1014862107
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 21146-21151
    • Li, Q.1    Vande Velde, C.2    Israelson, A.3    Xie, J.4    Bailey, A.O.5    Dong, M.Q.6    Chun, S.J.7    Roy, T.8    Winer, L.9    Yates, J.R.10
  • 42
    • 66749163493 scopus 로고    scopus 로고
    • Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration
    • PMID: 19492057
    • Gispert S, Ricciardi F, Kurz A, Azizov M, Hoepken HH, Becker D, Voos W, Leuner K, Müller WE, Kudin A P, et al. Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration. PLoS One 2009; 4:e5777; PMID: 19492057; http://dx.doi.org/10.1371/journal. pone.0005777
    • (2009) PLoS One , vol.4
    • Gispert, S.1    Ricciardi, F.2    Kurz, A.3    Azizov, M.4    Hoepken, H.H.5    Becker, D.6    Voos, W.7    Leuner, K.8    Müller, W.E.9    Kudin, A.P.10
  • 43
    • 33745280651 scopus 로고    scopus 로고
    • Biochemical analysis of Parkinson's disease-causing variants of Parkin, an E3 ubiquitin - Protein ligase with monoubiquitylation capacity
    • DOI 10.1093/hmg/ddl131
    • Hampe C, Ardila-Osorio H, Fournier M, Brice A, Corti O. Biochemical analysis of Parkinson's disease-causing variants of Parkin, an E3 ubiquitin-protein ligase with monoubiquitylation capacity. Hum Mol Genet 2006; 15: 2059-75; PMID: 1671430 0; http://dx.doi.org/10.1093/hmg/ddl131 (Pubitemid 43923396)
    • (2006) Human Molecular Genetics , vol.15 , Issue.13 , pp. 2059-2075
    • Hampe, C.1    Ardila-Osorio, H.2    Fournier, M.3    Brice, A.4    Corti, O.5


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