-
1
-
-
77049308856
-
Aging: A theory based on free radical and radiation chemistry
-
HARMAN, D. 1956. Aging: a theory based on free radical and radiation chemistry. J. Gerontol. 11: 298-300.
-
(1956)
J. Gerontol
, vol.11
, pp. 298-300
-
-
HARMAN, D.1
-
2
-
-
0036569401
-
Carbonyl modified proteins in cellular regulation, aging, and disease
-
LEVINE, R.L. 2002. Carbonyl modified proteins in cellular regulation, aging, and disease. Free Radic. Biol. Med. 32: 790-796.
-
(2002)
Free Radic. Biol. Med
, vol.32
, pp. 790-796
-
-
LEVINE, R.L.1
-
3
-
-
0034798361
-
Protein oxidation and 20S proteasome-dependent proteolysis in mammalian cells
-
SHRINGARPURE, R., T. GRUNE & K.J. DAVIES. 2001. Protein oxidation and 20S proteasome-dependent proteolysis in mammalian cells. Cell Mol. Life Sci. 58: 1442-1450.
-
(2001)
Cell Mol. Life Sci
, vol.58
, pp. 1442-1450
-
-
SHRINGARPURE, R.1
GRUNE, T.2
DAVIES, K.J.3
-
4
-
-
0036591853
-
Protein turnover by the proteasome in aging and disease
-
SHRINGARPURE, R. & K.J. DAVIES. 2002. Protein turnover by the proteasome in aging and disease. Free Radic. Biol. Med. 32: 1084-1089.
-
(2002)
Free Radic. Biol. Med
, vol.32
, pp. 1084-1089
-
-
SHRINGARPURE, R.1
DAVIES, K.J.2
-
6
-
-
0023811053
-
Normal oxidative damage to mitochondrial and nuclear DNA is extensive
-
RICHTER, C., J.W. PARK & B.N. AMES. 1988. Normal oxidative damage to mitochondrial and nuclear DNA is extensive. Proc. Natl. Acad. Sci. USA 85: 6465-6467.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 6465-6467
-
-
RICHTER, C.1
PARK, J.W.2
AMES, B.N.3
-
8
-
-
2642580016
-
Premature ageing in mice expressing defective mitochondrial DNA polymerase
-
TRIFUNOVIC, A. et al. 2004. Premature ageing in mice expressing defective mitochondrial DNA polymerase. Nature 429: 417-423.
-
(2004)
Nature
, vol.429
, pp. 417-423
-
-
TRIFUNOVIC, A.1
-
9
-
-
0033796250
-
Mitochondrial free radical generation, oxidative stress, and aging
-
CADENAS, E. & K.J. DAVIES. 2000. Mitochondrial free radical generation, oxidative stress, and aging. Free Radic. Biol. Med. 29: 222-230.
-
(2000)
Free Radic. Biol. Med
, vol.29
, pp. 222-230
-
-
CADENAS, E.1
DAVIES, K.J.2
-
10
-
-
33748201552
-
-
SZETO, H.H. 2006. Mitochondria-targeted peptide antioxidants: novel neuroprotective agents. AAPS J. 8: E521-531.
-
SZETO, H.H. 2006. Mitochondria-targeted peptide antioxidants: novel neuroprotective agents. AAPS J. 8: E521-531.
-
-
-
-
12
-
-
0029984892
-
Degradation of oxidized proteins in K562 human hematopoietic cells by proteasome
-
GRUNE, T., T. REINHECKEL & K.J. DAVIES. 1996. Degradation of oxidized proteins in K562 human hematopoietic cells by proteasome. J. Biol. Chem. 271: 15504-15509.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 15504-15509
-
-
GRUNE, T.1
REINHECKEL, T.2
DAVIES, K.J.3
-
13
-
-
0028912676
-
Proteolysis in cultured liver epithelial cells during oxidative stress. Role of the multicatalytic proteinase complex, proteasome
-
GRUNE, T. et al. 1995. Proteolysis in cultured liver epithelial cells during oxidative stress. Role of the multicatalytic proteinase complex, proteasome. J. Biol. Chem. 270: 2344-2351.
-
(1995)
J. Biol. Chem
, vol.270
, pp. 2344-2351
-
-
GRUNE, T.1
-
14
-
-
0036713692
-
Lon protease preferentially degrades oxidized mitochondrial aconitase by an ATP-stimulated mechanism
-
BOTA, D.A. & K.J. DAVIES. 2002. Lon protease preferentially degrades oxidized mitochondrial aconitase by an ATP-stimulated mechanism. Nat. Cell Biol. 4: 674-680.
-
(2002)
Nat. Cell Biol
, vol.4
, pp. 674-680
-
-
BOTA, D.A.1
DAVIES, K.J.2
-
15
-
-
33746578414
-
Slicing a protease: Structural features of the ATP-dependent Lon proteases gleaned from investigations of isolated domains
-
ROTANOVA, T.V. et al. 2006. Slicing a protease: structural features of the ATP-dependent Lon proteases gleaned from investigations of isolated domains. Protein Sci. 15: 1815-1828.
-
(2006)
Protein Sci
, vol.15
, pp. 1815-1828
-
-
ROTANOVA, T.V.1
-
16
-
-
0032969563
-
AAA+: A class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes
-
NEUWALD, A.F. et al. 1999. AAA+: a class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes. Genome Res. 9: 27-43.
-
(1999)
Genome Res
, vol.9
, pp. 27-43
-
-
NEUWALD, A.F.1
-
17
-
-
21644454699
-
Cleavage site selection within a folded substrate by the ATP-dependent lon protease
-
ONDROVICOVA, G. et al. 2005. Cleavage site selection within a folded substrate by the ATP-dependent lon protease. J. Biol. Chem. 280: 25103-25110.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 25103-25110
-
-
ONDROVICOVA, G.1
-
18
-
-
1842690145
-
DNA and RNA binding by the mitochondrial lon protease is regulated by nucleotide and protein substrate
-
LIU, T. et al. 2004. DNA and RNA binding by the mitochondrial lon protease is regulated by nucleotide and protein substrate. J. Biol. Chem. 279: 13902-13910.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 13902-13910
-
-
LIU, T.1
-
19
-
-
0033610079
-
Gene expression profile of aging and its retardation by caloric restriction
-
LEE, C.K. et al. 1999. Gene expression profile of aging and its retardation by caloric restriction. Science 285: 1390-1393.
-
(1999)
Science
, vol.285
, pp. 1390-1393
-
-
LEE, C.K.1
-
20
-
-
0037021453
-
Modulation of Lon protease activity and aconitase turnover during aging and oxidative stress
-
BOTA, D.A., H. VAN REMMEN & K.J. DAVIES. 2002. Modulation of Lon protease activity and aconitase turnover during aging and oxidative stress. FEBS Lett. 532: 103-106.
-
(2002)
FEBS Lett
, vol.532
, pp. 103-106
-
-
BOTA, D.A.1
VAN REMMEN, H.2
DAVIES, K.J.3
-
21
-
-
15744384860
-
Downregulation of the human Lon protease impairs mitochondrial structure and function and causes cell death
-
BOTA, D.A., J.K. NGO & K.J. DAVIES. 2005. Downregulation of the human Lon protease impairs mitochondrial structure and function and causes cell death. Free Radic. Biol. Med. 38: 665-677.
-
(2005)
Free Radic. Biol. Med
, vol.38
, pp. 665-677
-
-
BOTA, D.A.1
NGO, J.K.2
DAVIES, K.J.3
-
22
-
-
0037517056
-
Changes in rat liver mitochondria with aging. Lon protease-like reactivity and N(epsilon)-carboxymethyllysine accumulation in the matrix
-
BAKALA, H. et al. 2003. Changes in rat liver mitochondria with aging. Lon protease-like reactivity and N(epsilon)-carboxymethyllysine accumulation in the matrix. Eur. J. Biochem. 270: 2295-2302.
-
(2003)
Eur. J. Biochem
, vol.270
, pp. 2295-2302
-
-
BAKALA, H.1
-
23
-
-
9644301105
-
Age-related impairment of mitochondrial matrix aconitase and ATP-stimulated protease in rat liver and heart
-
DELAVAL, E., M. PERICHON & B. FRIGUET. 2004. Age-related impairment of mitochondrial matrix aconitase and ATP-stimulated protease in rat liver and heart. Eur. J. Biochem. 271: 4559-4564.
-
(2004)
Eur. J. Biochem
, vol.271
, pp. 4559-4564
-
-
DELAVAL, E.1
PERICHON, M.2
FRIGUET, B.3
-
24
-
-
0029762950
-
-
REP, M. et al. 1996. Promotion of mitochondrial membrane complex assembly by a proteolytically inactive yeast Lon. Science 274: 103-106.
-
REP, M. et al. 1996. Promotion of mitochondrial membrane complex assembly by a proteolytically inactive yeast Lon. Science 274: 103-106.
-
-
-
-
25
-
-
13244277441
-
Aconitase couples metabolic regulation to mitochondrial DNA maintenance
-
CHEN, X.J. et al. 2005. Aconitase couples metabolic regulation to mitochondrial DNA maintenance. Science 307: 714-717.
-
(2005)
Science
, vol.307
, pp. 714-717
-
-
CHEN, X.J.1
-
26
-
-
20444369173
-
MitochondrialDNA, aconitase 'wraps' it up
-
SHADEL, G.S. 2005. MitochondrialDNA, aconitase 'wraps' it up. Trends Biochem. Sci. 30: 294-296.
-
(2005)
Trends Biochem. Sci
, vol.30
, pp. 294-296
-
-
SHADEL, G.S.1
-
27
-
-
0000989147
-
Aconitase as Ironminus signSulfur Protein, Enzyme, and Iron-Regulatory Protein
-
BEINERT, H., M.C. KENNEDY & C.D. STOUT. 1996. Aconitase as Ironminus signSulfur Protein, Enzyme, and Iron-Regulatory Protein. Chem. Rev. 96: 2335-2374.
-
(1996)
Chem. Rev
, vol.96
, pp. 2335-2374
-
-
BEINERT, H.1
KENNEDY, M.C.2
STOUT, C.D.3
-
28
-
-
0036121191
-
Aconitase: Sensitive target and measure of superoxide
-
GARDNER, P.R. 2002. Aconitase: sensitive target and measure of superoxide. Methods Enzymol. 349: 9-23.
-
(2002)
Methods Enzymol
, vol.349
, pp. 9-23
-
-
GARDNER, P.R.1
-
29
-
-
0346365099
-
Redox-dependent modulation of aconitase activity in intact mitochondria
-
BULTEAU, A.L., M. IKEDA-SAITO & L.I. SZWEDA. 2003. Redox-dependent modulation of aconitase activity in intact mitochondria. Biochemistry 42: 14846-14855.
-
(2003)
Biochemistry
, vol.42
, pp. 14846-14855
-
-
BULTEAU, A.L.1
IKEDA-SAITO, M.2
SZWEDA, L.I.3
-
30
-
-
33745378112
-
Control of mitochondrial gene expression in the aging rat myocardium
-
LEMOINE, C.M. et al. 2006. Control of mitochondrial gene expression in the aging rat myocardium. Biochem. Cell Biol. 84: 191-198.
-
(2006)
Biochem. Cell Biol
, vol.84
, pp. 191-198
-
-
LEMOINE, C.M.1
-
31
-
-
32444443812
-
Age-dependent cell death and the role of ATP in hydrogen peroxide-induced apoptosis and necrosis
-
MIYOSHI, N. et al. 2006. Age-dependent cell death and the role of ATP in hydrogen peroxide-induced apoptosis and necrosis. Proc. Natl. Acad. Sci. USA 103: 1727-1731.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 1727-1731
-
-
MIYOSHI, N.1
|