Antiprotozoal activity of chloroquinoline based chalcones

European Journal of Medicinal Chemistry

Volumn 46, Issue 5, 2011, Pages 1897-1905

  Hayat, Faisal ^a   Moseley, Emma ^b   Salahuddin, Attar ^a   Van Zyl, Robyn L ^b   Azam, Amir ^a  

^a JAMIA MILLIA ISLAMIA CENTRAL UNIVERSITY   (India)

^b UNIVERSITY OF THE WITWATERSRAND   (South Africa)

Author keywords

Haematin; 2 Chloro 3 formylquinolines; Anti oxidant; Aromatic ketones; Chalcones; Cytotoxicity; Entamoeba histolytica; Haemolysis; Plasmodium falciparum

Indexed keywords

1 (3 BROMOPHENYL) 3 (2 CHLORO 6 METHYLQUINOLIN 3 YL) 2 METHYLPROP 2 EN 1 ONE; 1 (3 BROMOPHENYL) 3 (2 CHLORO 6 METHYLQUINOLIN 3 YL)PROP 2 EN 1 ONE; 1 (3 BROMOPHENYL) 3 (2 CHLORO 7 METHYLQUINOLINE 3YL) 2 METHYLPROP 2 EN 1 ONE; 1 (3 BROMOPHENYL) 3 (2 CHLORO 7 METHYLQUINOLINE 3YL)PROP 2 EN 1 ONE; 1 (3 BROMOPHENYL) 3 (2 CHLOROQUINOLINE 3YL) 2 METHYLPROP 2 EN 1 ONE; 1 (3 BROMOPHENYL) 3 (2 CHLOROQUINOLINE 3YL) PROP 2 EN 1 ONE; 1 (4 BROMOPHENYL) 3 (2 CHLORO 6 METHYLQUINOLINE 3YL)PROP 2 EN 1 ONE; 1 (4 BROMOPHENYL) 3 (2 CHLOROQUINOLINE 3YL)PROP 2 EN 1 ONE; 1 (4 CHLOROPHENYL) 3 (2 CHLOROQUINOLINE 3YL)PROP 2 EN 1 ONE; 2 CHLORO 3 FORMYLQUINOLINE DERIVATIVE; 3 (2 CHLORO 6 METHYLQUINOLIN 3 YL) 1 (3 CHLOROPHENYL) 2 METHYLPROP 2 EN 1 ONE; 3 (2 CHLORO 6 METHYLQUINOLINE 3YL) 1 (PYRIDINE 2YL)PROP 2 EN 1 ONE; 3 (2 CHLORO 7 METHYLQUINOLIN 3 YL) 1 (4 CHLOROPHENYL)PROP 2 EN 1 ONE; 3 (2 CHLORO 7 METHYLQUINOLINE 3YL) 1 (3 CHLOROPHENYL) 2 METHYLPROP 2 EN 1 ONE; 3 (2 CHLORO 7 METHYLQUINOLINE 3YL) 1 (PYRIDINE 2YL)PROP 2 EN 1 ONE; 3 (2 CHLOROQUINOLINE 3YL) 1 (PYRIDINE 2YL)PROP 2 EN 1 ONE; ANTIPROTOZOAL AGENT; CHALCONE DERIVATIVE; CHLOROQUINE; CHLOROQUINOLINE; METRONIDAZOLE; QUININE; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ANTIPROTOZOAL ACTIVITY; ARTICLE; CELL STRAIN MCF 7; DRUG STRUCTURE; DRUG SYNTHESIS; ENTAMOEBA HISTOLYTICA; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; NONHUMAN; PLASMODIUM FALCIPARUM;

ANTIPROTOZOAL AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; CHALCONES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; ENTAMOEBA HISTOLYTICA; HUMANS; MOLECULAR STRUCTURE; PARASITIC SENSITIVITY TESTS; PLASMODIUM FALCIPARUM; QUINOLINES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79953209677     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2011.02.004     Document Type: Article

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