메뉴 건너뛰기




Volumn 32, Issue 45, 2013, Pages 5283-5291

STK38 is a critical upstream regulator of MYC's oncogenic activity in human B-cell lymphoma

Author keywords

MYC post translational modifications; protein turnover; protein protein interaction; STK38; transcriptional activity

Indexed keywords

B LYMPHOCYTE RECEPTOR; MYC PROTEIN; PROTEIN SERINE THREONINE KINASE; PROTEIN SERINE THREONINE KINASE 38; UNCLASSIFIED DRUG;

EID: 84887470070     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2012.543     Document Type: Article
Times cited : (43)

References (52)
  • 1
    • 33646422520 scopus 로고    scopus 로고
    • The human tumour suppressor LATS1 is activated by human MOB1 at the membrane
    • Hergovich A, Schmitz D, Hemmings BA. The human tumour suppressor LATS1 is activated by human MOB1 at the membrane. Biochem Biophys Res Commun 2006; 345: 50-58.
    • (2006) Biochem Biophys Res Commun , vol.345 , pp. 50-58
    • Hergovich, A.1    Schmitz, D.2    Hemmings, B.A.3
  • 3
    • 70249108504 scopus 로고    scopus 로고
    • Genomewide identification of post-translational modulators of transcription factor activity in human B cells
    • Wang K, Saito M, Bisikirska BC, Alvarez MJ, Lim WK, Rajbhandari P et al. Genomewide identification of post-translational modulators of transcription factor activity in human B cells. Nat Biotechnol 2009; 27: 829-839.
    • (2009) Nat Biotechnol , vol.27 , pp. 829-839
    • Wang, K.1    Saito, M.2    Bisikirska, B.C.3    Alvarez, M.J.4    Lim, W.K.5    Rajbhandari, P.6
  • 4
    • 0842278571 scopus 로고    scopus 로고
    • An integrated database of genes responsive to the Myc oncogenic transcription factor: Identification of direct genomic targets
    • Zeller KI, Jegga AG, Aronow BJ, ODonnell KA, Dang CV. An integrated database of genes responsive to the Myc oncogenic transcription factor: identification of direct genomic targets. Genome Biol 2003; 4: R69.
    • (2003) Genome Biol , vol.4
    • Zeller, K.I.1    Jegga, A.G.2    Aronow, B.J.3    Odonnell, K.A.4    Dang, C.V.5
  • 5
    • 0029006372 scopus 로고
    • Molecular cloning and characterization of a conserved nuclear serine(threonine) protein kinase
    • Millward T, Cron P, Hemmings BA. Molecular cloning and characterization of a conserved nuclear serine(threonine) protein kinase. Proc Natl Acad Sci USA 1995; 92(11): 5022-5026.
    • (1995) Proc Natl Acad Sci USA , vol.92 , Issue.11 , pp. 5022-5026
    • Millward, T.1    Cron, P.2    Hemmings, B.A.3
  • 6
    • 33847080309 scopus 로고    scopus 로고
    • Centrosome-associated NDR kinase regulates centrosome duplication
    • Hergovich A, Lamla S, Nigg EA, Hemmings BA. Centrosome-associated NDR kinase regulates centrosome duplication. Mol Cell 2007; 25: 625-634.
    • (2007) Mol Cell , vol.25 , pp. 625-634
    • Hergovich, A.1    Lamla, S.2    Nigg, E.A.3    Hemmings, B.A.4
  • 7
    • 41149105368 scopus 로고    scopus 로고
    • Negative regulation of MEKK1/2 signaling by serine-threonine kinase 38 (STK38)
    • Enomoto A, Kido N, Ito M, Morita A, Matsumoto Y, Takamatsu N et al. Negative regulation of MEKK1/2 signaling by serine-threonine kinase 38 (STK38). Oncogene 2008; 27: 1930-1938.
    • (2008) Oncogene , vol.27 , pp. 1930-1938
    • Enomoto, A.1    Kido, N.2    Ito, M.3    Morita, A.4    Matsumoto, Y.5    Takamatsu, N.6
  • 8
    • 0037470184 scopus 로고    scopus 로고
    • Mechanism of Ca2-mediated regulation of NDR protein kinase through autophosphorylation and phosphorylation by an upstream kinase
    • Tamaskovic R, Bichsel SJ, Rogniaux H, Stegert MR, Hemmings BA. Mechanism of Ca2-mediated regulation of NDR protein kinase through autophosphorylation and phosphorylation by an upstream kinase. J Biol Chem 2003; 278: 6710-6718.
    • (2003) J Biol Chem , vol.278 , pp. 6710-6718
    • Tamaskovic, R.1    Bichsel, S.J.2    Rogniaux, H.3    Stegert, M.R.4    Hemmings, B.A.5
  • 9
    • 0347481143 scopus 로고    scopus 로고
    • Structure of the Ca2/S100B/NDR kinase peptide complex: Insights into S100 target specificity and activation of the kinase
    • Bhattacharya S, Large E, Heizmann CW, Hemmings B, Chazin WJ. Structure of the Ca2/S100B/NDR kinase peptide complex: insights into S100 target specificity and activation of the kinase. Biochemistry 2003; 42: 14416-14426.
    • (2003) Biochemistry , vol.42 , pp. 14416-14426
    • Bhattacharya, S.1    Large, E.2    Heizmann, C.W.3    Hemmings, B.4    Chazin, W.J.5
  • 10
    • 2642546543 scopus 로고    scopus 로고
    • Human Mob proteins regulate the NDR1 and NDR2 serine-threonine kinases
    • Devroe E, Erdjument-Bromage H, Tempst P, Silver PA. Human Mob proteins regulate the NDR1 and NDR2 serine-threonine kinases. J Biol Chem 2004; 279: 24444-24451.
    • (2004) J Biol Chem , vol.279 , pp. 24444-24451
    • Devroe, E.1    Erdjument-Bromage, H.2    Tempst, P.3    Silver, P.A.4
  • 11
    • 0033607636 scopus 로고    scopus 로고
    • Ndr protein kinase is regulated by phosphorylation on two conserved sequence motifs
    • Millward TA, Hess D, Hemmings BA. Ndr protein kinase is regulated by phosphorylation on two conserved sequence motifs. J Biol Chem 1999; 274: 33847-33850.
    • (1999) J Biol Chem , vol.274 , pp. 33847-33850
    • Millward, T.A.1    Hess, D.2    Hemmings, B.A.3
  • 14
    • 0842303173 scopus 로고    scopus 로고
    • Reversibility of oncogene-induced cancer
    • Felsher DW. Reversibility of oncogene-induced cancer. Curr Opin Genet Dev 2004; 14: 37-42.
    • (2004) Curr Opin Genet Dev , vol.14 , pp. 37-42
    • Felsher, D.W.1
  • 15
    • 0037025173 scopus 로고    scopus 로고
    • Cancer addiction to oncogenes-The Achilles heal of cancer
    • Weinstein IB. Cancer. Addiction to oncogenes-the Achilles heal of cancer.. Science 2002; 297: 63-64.
    • (2002) Science , vol.297 , pp. 63-64
    • Weinstein, I.B.1
  • 16
    • 80053649037 scopus 로고    scopus 로고
    • Survival and death signals can predict tumor response to therapy after oncogene inactivation
    • Tran PT, Bendapudi PK, Lin HJ, Choi P, Koh S, Chen J et al. Survival and death signals can predict tumor response to therapy after oncogene inactivation. Sci Transl Med 2011; 3: 103ra99.
    • (2011) Sci Transl Med , vol.3
    • Tran, P.T.1    Bendapudi, P.K.2    Lin, H.J.3    Choi, P.4    Koh, S.5    Chen, J.6
  • 17
    • 0742304320 scopus 로고    scopus 로고
    • Oncogenes as therapeutic targets
    • Felsher DW. Oncogenes as therapeutic targets. Semin Cancer Biol 2004; 14: 1.
    • (2004) Semin Cancer Biol , vol.14 , pp. 1
    • Felsher, D.W.1
  • 18
    • 57649102412 scopus 로고    scopus 로고
    • NDR kinase is activated by RASSF1A/MST1 in response to Fas receptor stimulation and promotes apoptosis
    • Vichalkovski A, Gresko E, Cornils H, Hergovich A, Schmitz D, Hemmings BA. NDR kinase is activated by RASSF1A/MST1 in response to Fas receptor stimulation and promotes apoptosis. Curr Biol 2008; 18: 1889-1895.
    • (2008) Curr Biol , vol.18 , pp. 1889-1895
    • Vichalkovski, A.1    Gresko, E.2    Cornils, H.3    Hergovich, A.4    Schmitz, D.5    Hemmings, B.A.6
  • 19
    • 0029744422 scopus 로고    scopus 로고
    • Anti-IgMmediated regulation of c-myc and its possible relationship to apoptosis
    • Kaptein JS, Lin CK, Wang CL, Nguyen TT, Kalunta CI, Park E et al. Anti-IgMmediated regulation of c-myc and its possible relationship to apoptosis. J Biol Chem 1996; 271: 18875-18884.
    • (1996) J Biol Chem , vol.271 , pp. 18875-18884
    • Kaptein, J.S.1    Lin, C.K.2    Wang, C.L.3    Nguyen, T.T.4    Kalunta, C.I.5    Park, E.6
  • 20
    • 79953799132 scopus 로고    scopus 로고
    • Human NDR kinases control G(1)/S cell cycle transition by directly regulating p21 stability
    • Cornils H, Kohler RS, Hergovich A, Hemmings BA. Human NDR kinases control G(1)/S cell cycle transition by directly regulating p21 stability. Mol Cell Biol 2011; 31: 1382-1395.
    • (2011) Mol Cell Biol , Issue.31 , pp. 1382-1395
    • Cornils, H.1    Kohler, R.S.2    Hergovich, A.3    Hemmings, B.A.4
  • 24
    • 0033180211 scopus 로고    scopus 로고
    • Reversible tumorigenesis by MYC in hematopoietic lineages
    • Felsher DW, Bishop JM. Reversible tumorigenesis by MYC in hematopoietic lineages. Mol Cell 1999; 4: 199-207.
    • (1999) Mol Cell , vol.4 , pp. 199-207
    • Felsher, D.W.1    Bishop, J.M.2
  • 25
    • 80555139622 scopus 로고    scopus 로고
    • Genome-wide dissection of posttranscriptional and posttranslational interactions
    • Bansal M, Califano A. Genome-wide dissection of posttranscriptional and posttranslational interactions. Methods Mol Biol 2012; 786: 131-149.
    • (2012) Methods Mol Biol , Issue.786 , pp. 131-149
    • Bansal, M.1    Califano, A.2
  • 27
    • 0032531742 scopus 로고    scopus 로고
    • Calcium regulation of Ndr protein kinase mediated by S100 calcium-binding proteins
    • Millward TA, Heizmann CW, Schafer BW, Hemmings BA. Calcium regulation of Ndr protein kinase mediated by S100 calcium-binding proteins. EMBO J 1998; 17: 5913-5922.
    • (1998) EMBO J , vol.17 , pp. 5913-5922
    • Millward, T.A.1    Heizmann, C.W.2    Schafer, B.W.3    Hemmings, B.A.4
  • 30
    • 33748138585 scopus 로고    scopus 로고
    • Role of post-translational modifications in regulating c-Myc proteolysis, transcriptional activity and biological function
    • Hann SR. Role of post-translational modifications in regulating c-Myc proteolysis, transcriptional activity and biological function. Semin Cancer Biol 2006; 16: 288-302.
    • (2006) Semin Cancer Biol , vol.16 , pp. 288-302
    • Hann, S.R.1
  • 32
    • 0033551388 scopus 로고    scopus 로고
    • New Myc-interacting proteins: A second Myc network emerges
    • Sakamuro D, Prendergast GC. New Myc-interacting proteins: a second Myc network emerges. Oncogene 1999; 18: 2942-2954.
    • (1999) Oncogene , vol.18 , pp. 2942-2954
    • Sakamuro, D.1    Prendergast, G.C.2
  • 34
    • 2342507059 scopus 로고    scopus 로고
    • Multiple cell-type-specific elements regulate Myc protein stability
    • Herbst A, Salghetti SE, Kim SY, Tansey WP. Multiple cell-type-specific elements regulate Myc protein stability. Oncogene 2004; 23: 3863-3871.
    • (2004) Oncogene , vol.23 , pp. 3863-3871
    • Herbst, A.1    Salghetti, S.E.2    Kim, S.Y.3    Tansey, W.P.4
  • 35
    • 0025166030 scopus 로고
    • An amino-terminal c-myc domain required for neoplastic transformation activates transcription
    • Kato GJ, Barrett J, Villa-Garcia M, Dang CV. An amino-terminal c-myc domain required for neoplastic transformation activates transcription. Mol Cell Biol 1990; 10: 5914-5920.
    • (1990) Mol Cell Biol , vol.10 , pp. 5914-5920
    • Kato, G.J.1    Barrett, J.2    Villa-Garcia, M.3    Dang, C.V.4
  • 37
    • 1642441902 scopus 로고    scopus 로고
    • Docking interactions in the c-Jun N-terminal kinase pathway
    • Mooney LM, Whitmarsh AJ. Docking interactions in the c-Jun N-terminal kinase pathway. J Biol Chem 2004; 279: 11843-11852.
    • (2004) J Biol Chem , vol.279 , pp. 11843-11852
    • Mooney, L.M.1    Whitmarsh, A.J.2
  • 38
    • 0033571527 scopus 로고    scopus 로고
    • Proteasome-mediated degradation of transcriptional activators correlates with activation domain potency in vivo
    • Molinari E, Gilman M, Natesan S. Proteasome-mediated degradation of transcriptional activators correlates with activation domain potency in vivo. EMBO J 1999; 18: 6439-6447.
    • (1999) EMBO J , vol.18 , pp. 6439-6447
    • Molinari, E.1    Gilman, M.2    Natesan, S.3
  • 42
    • 56049097680 scopus 로고    scopus 로고
    • Structural rationale for the coupled binding and unfolding of the c-Myc oncoprotein by small molecules
    • Follis AV, Hammoudeh DI, Wang H, Prochownik EV, Metallo SJ. Structural rationale for the coupled binding and unfolding of the c-Myc oncoprotein by small molecules. Chem Biol 2008; 15: 1149-1155.
    • (2008) Chem Biol , vol.15 , pp. 1149-1155
    • Follis, A.V.1    Hammoudeh, D.I.2    Wang, H.3    Prochownik, E.V.4    Metallo, S.J.5
  • 43
    • 1542358787 scopus 로고    scopus 로고
    • Prediction and functional analysis of native disorder in proteins from the three kingdoms of life
    • Ward JJ, Sodhi JS, McGuffin LJ, Buxton BF, Jones DT. Prediction and functional analysis of native disorder in proteins from the three kingdoms of life. J Mol Biol 2004; 337: 635-645.
    • (2004) J Mol Biol , vol.337 , pp. 635-645
    • Ward, J.J.1    Sodhi, J.S.2    McGuffin, L.J.3    Buxton, B.F.4    Jones, D.T.5
  • 44
    • 70350308428 scopus 로고    scopus 로고
    • Susceptibility of p53 unstructured N terminus to 20 S proteasomal degradation programs the stress response
    • Tsvetkov P, Reuven N, Prives C, Shaul Y. Susceptibility of p53 unstructured N terminus to 20 S proteasomal degradation programs the stress response. J Biol Chem 2009; 284: 26234-26242.
    • (2009) J Biol Chem , vol.284 , pp. 26234-26242
    • Tsvetkov, P.1    Reuven, N.2    Prives, C.3    Shaul, Y.4
  • 46
    • 3042522892 scopus 로고    scopus 로고
    • Stress-activated protein kinases-tumor suppressors or tumor initiators?
    • Engelberg D. Stress-activated protein kinases-tumor suppressors or tumor initiators? Semin Cancer Biol 2004; 14: 271-282.
    • (2004) Semin Cancer Biol , vol.14 , pp. 271-282
    • Engelberg, D.1
  • 47
    • 79959240968 scopus 로고    scopus 로고
    • Downstream of human NDR kinases: Impacting on c-myc and p21 protein stability to control cell cycle progression
    • Cornils H, Kohler RS, Hergovich A, Hemmings BA. Downstream of human NDR kinases: impacting on c-myc and p21 protein stability to control cell cycle progression. Cell Cycle 2011; 10: 1897-1904.
    • (2011) Cell Cycle , pp. 10
    • Cornils, H.1    Kohler, R.S.2    Hergovich, A.3    Hemmings, B.A.4
  • 48
    • 0037025201 scopus 로고    scopus 로고
    • Sustained loss of a neoplastic phenotype by brief inactivation of MYC
    • Jain M, Arvanitis C, Chu K, Dewey W, Leonhardt E, Trinh M et al. Sustained loss of a neoplastic phenotype by brief inactivation of MYC. Science 2002; 297: 102-104.
    • (2002) Science , vol.297 , pp. 102-104
    • Jain, M.1    Arvanitis, C.2    Chu, K.3    Dewey, W.4    Leonhardt, E.5    Trinh, M.6
  • 49
    • 0038107350 scopus 로고    scopus 로고
    • Genomically complex lymphomas undergo sustained tumor regression upon MYC inactivation unless they acquire novel chromosomal translocations
    • Karlsson A, Giuriato S, Tang F, Fung-Weier J, Levan G, Felsher DW. Genomically complex lymphomas undergo sustained tumor regression upon MYC inactivation unless they acquire novel chromosomal translocations. Blood 2003; 101: 2797-2803.
    • (2003) Blood , vol.101 , pp. 2797-2803
    • Karlsson, A.1    Giuriato, S.2    Tang, F.3    Fung-Weier, J.4    Levan, G.5    Felsher, D.W.6
  • 51
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
    • Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. ProcNatl Acad SciUSA 2005; 102(43): 15545-15550.
    • (2005) ProcNatl Acad SciUSA , vol.102 , Issue.43 , pp. 15545-15550
    • Subramanian, A.1    Tamayo, P.2    Mootha, V.K.3    Mukherjee, S.4    Ebert, B.L.5    Gillette, M.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.