-
1
-
-
83055173820
-
Efficient conversion of astrocytes to functional midbrain dopaminergic neurons using a single polycistronic vector
-
Addis RC, Hsu FC, Wright RL, Dichter MA, Coulter DA, Gearhart JD. Efficient conversion of astrocytes to functional midbrain dopaminergic neurons using a single polycistronic vector. PLoS One. 2011 ; 6 ( 12 ):
-
(2011)
PLoS One
, vol.6
, Issue.12
-
-
Addis, R.C.1
Hsu, F.C.2
Wright, R.L.3
Dichter, M.A.4
Coulter, D.A.5
Gearhart, J.D.6
-
2
-
-
83255189758
-
Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage
-
Amps K, Andrews PW, Anyfantis G, Armstrong L, Avery S, Baharvand H. Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage. Nat Biotechnol. 2011 ; 29 (12). 1132-44
-
(2011)
Nat Biotechnol
, vol.29
, Issue.12
, pp. 1132-1144
-
-
Amps, K.1
Andrews, P.W.2
Anyfantis, G.3
Armstrong, L.4
Avery, S.5
Baharvand, H.6
-
3
-
-
84864631163
-
Genetic correction of Huntington's disease phenotypes in induced pluripotent stem cells
-
An MC, Zhang N, Scott G, Montoro D, Wittkop T, Mooney S. Genetic correction of Huntington's disease phenotypes in induced pluripotent stem cells. Cell Stem Cell. 2012 ; 11 (2). 253-63
-
(2012)
Cell Stem Cell
, vol.11
, Issue.2
, pp. 253-263
-
-
An, M.C.1
Zhang, N.2
Scott, G.3
Montoro, D.4
Wittkop, T.5
Mooney, S.6
-
4
-
-
31044445499
-
Identification of intrinsic determinants of midbrain dopamine neurons
-
Andersson E, Tryggvason U, Deng Q, Friling S, Alekseenko Z, Robert B. Identification of intrinsic determinants of midbrain dopamine neurons. Cell. 2006 ; 124 (2). 393-405
-
(2006)
Cell
, vol.124
, Issue.2
, pp. 393-405
-
-
Andersson, E.1
Tryggvason, U.2
Deng, Q.3
Friling, S.4
Alekseenko, Z.5
Robert, B.6
-
5
-
-
0028907753
-
Embryonic stem cells express neuronal properties in vitro
-
Bain G, Kitchens D, Yao M, Huettner JE, Gottlieb DI. Embryonic stem cells express neuronal properties in vitro. Dev Biol. 1995 ; 168 (2). 342-57
-
(1995)
Dev Biol
, vol.168
, Issue.2
, pp. 342-357
-
-
Bain, G.1
Kitchens, D.2
Yao, M.3
Huettner, J.E.4
Gottlieb, D.I.5
-
6
-
-
33846879559
-
Adaptation to culture of human embryonic stem cells and oncogenesis in vivo
-
Baker DE, Harrison NJ, Maltby E, Smith K, Moore HD, Shaw PJ. Adaptation to culture of human embryonic stem cells and oncogenesis in vivo. Nat Biotechnol. 2007 ; 25 (2). 207-15
-
(2007)
Nat Biotechnol
, vol.25
, Issue.2
, pp. 207-215
-
-
Baker, D.E.1
Harrison, N.J.2
Maltby, E.3
Smith, K.4
Moore, H.D.5
Shaw, P.J.6
-
7
-
-
84867839464
-
Induced pluripotent stem cells: The new patient?
-
Bellin M, Marchetto MC, Gage FH, Mummery CL. Induced pluripotent stem cells: the new patient?. Nat Rev Mol Cell Biol. 2012 ; 13 (11). 713-26
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, Issue.11
, pp. 713-726
-
-
Bellin, M.1
Marchetto, M.C.2
Gage, F.H.3
Mummery, C.L.4
-
8
-
-
0020960766
-
Cytoplasmic activation of human nuclear genes in stable heterocaryons
-
Blau HM, Chiu CP, Webster C. Cytoplasmic activation of human nuclear genes in stable heterocaryons. Cell. 1983 ; 32 (4). 1171-80
-
(1983)
Cell
, vol.32
, Issue.4
, pp. 1171-1180
-
-
Blau, H.M.1
Chiu, C.P.2
Webster, C.3
-
9
-
-
0022367980
-
Plasticity of the differentiated state
-
Blau HM, Pavlath GK, Hardeman EC, Chiu CP, Silberstein L, Webster SG. Plasticity of the differentiated state. Science. 1985 ; 230 (4727). 758-66
-
(1985)
Science
, vol.230
, Issue.4727
, pp. 758-766
-
-
Blau, H.M.1
Pavlath, G.K.2
Hardeman, E.C.3
Chiu, C.P.4
Silberstein, L.5
Webster, S.G.6
-
10
-
-
79551665440
-
A functionally characterized test set of human induced pluripotent stem cells
-
Boulting GL, Kiskinis E, Croft GF, Amoroso MW, Oakley DH, Wainger BJ. A functionally characterized test set of human induced pluripotent stem cells. Nat Biotechnol. 2011 ; 29 (3). 279-86
-
(2011)
Nat Biotechnol
, vol.29
, Issue.3
, pp. 279-286
-
-
Boulting, G.L.1
Kiskinis, E.2
Croft, G.F.3
Amoroso, M.W.4
Oakley, D.H.5
Wainger, B.J.6
-
11
-
-
80051674431
-
Direct generation of functional dopaminergic neurons from mouse and human fibroblasts
-
Caiazzo M, Dell'Anno MT, Dvoretskova E, Lazarevic D, Taverna S, Leo D. Direct generation of functional dopaminergic neurons from mouse and human fibroblasts. Nature. 2011 ; 476 (7359). 224-7
-
(2011)
Nature
, vol.476
, Issue.7359
, pp. 224-227
-
-
Caiazzo, M.1
Dell'Anno, M.T.2
Dvoretskova, E.3
Lazarevic, D.4
Taverna, S.5
Leo, D.6
-
12
-
-
84863230167
-
The first reported generation of several induced pluripotent stem cell lines from homozygous and heterozygous Huntington's disease patients demonstrates mutation related enhanced lysosomal activity
-
Camnasio S, Carri AD, Lombardo A, Grad I, Mariotti C, Castucci A. The first reported generation of several induced pluripotent stem cell lines from homozygous and heterozygous Huntington's disease patients demonstrates mutation related enhanced lysosomal activity. Neurobiol Dis. 2012 ; 46 (1). 41-51
-
(2012)
Neurobiol Dis
, vol.46
, Issue.1
, pp. 41-51
-
-
Camnasio, S.1
Carri, A.D.2
Lombardo, A.3
Grad, I.4
Mariotti, C.5
Castucci, A.6
-
13
-
-
84866161727
-
SOX2 gene regulates the transcriptional network of oncogenes and affects tumorigenesis of human lung cancer cells
-
Chen S, Xu Y, Chen Y, Li X, Mou W, Wang L. SOX2 gene regulates the transcriptional network of oncogenes and affects tumorigenesis of human lung cancer cells. PLoS One. 2012 ; 7 (5). e36326
-
(2012)
PLoS One
, vol.7
, Issue.5
, pp. 36326
-
-
Chen, S.1
Xu, Y.2
Chen, Y.3
Li, X.4
Mou, W.5
Wang, L.6
-
14
-
-
67649222358
-
Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures
-
Chin MH, Mason MJ, Xie W, Volinia S, Singer M, Peterson C. Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures. Cell Stem Cell. 2009 ; 5 (1). 111-23
-
(2009)
Cell Stem Cell
, vol.5
, Issue.1
, pp. 111-123
-
-
Chin, M.H.1
Mason, M.J.2
Xie, W.3
Volinia, S.4
Singer, M.5
Peterson, C.6
-
15
-
-
84863584524
-
Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease
-
Cooper O, Seo H, Andrabi S, Guardia-Laguarta C, Graziotto J, Sundberg M. Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease. Sci Transl Med. 2012 ; 4 (141). 141ra90
-
(2012)
Sci Transl Med
, vol.4
, Issue.141
-
-
Cooper, O.1
Seo, H.2
Andrabi, S.3
Guardia-Laguarta, C.4
Graziotto, J.5
Sundberg, M.6
-
16
-
-
50149098605
-
Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons
-
Dimos JT, Rodolfa KT, Niakan KK, Weisenthal LM, Mitsumoto H, Chung W. Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons. Science. 2008 ; 321 (5893). 1218-21
-
(2008)
Science
, vol.321
, Issue.5893
, pp. 1218-1221
-
-
Dimos, J.T.1
Rodolfa, K.T.2
Niakan, K.K.3
Weisenthal, L.M.4
Mitsumoto, H.5
Chung, W.6
-
17
-
-
0242321829
-
The glial identity of neural stem cells
-
Doetsch F. The glial identity of neural stem cells. Nat Neurosci. 2003 ; 6 (11). 1127-34
-
(2003)
Nat Neurosci
, vol.6
, Issue.11
, pp. 1127-1134
-
-
Doetsch, F.1
-
18
-
-
58249110796
-
Induced pluripotent stem cells from a spinal muscular atrophy patient
-
Ebert AD, Yu J, Rose FF, Mattis VB, Lorson CL, Thomson JA. Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature. 2009 ; 457 (7227). 277-80
-
(2009)
Nature
, vol.457
, Issue.7227
, pp. 277-280
-
-
Ebert, A.D.1
Yu, J.2
Rose, F.F.3
Mattis, V.B.4
Lorson, C.L.5
Thomson, J.A.6
-
19
-
-
79952273710
-
Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy
-
Efe JA, Hilcove S, Kim J, Zhou H, Ouyang K, Wang G. Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy. Nat Cell Biol. 2011 ; 13 (3). 215-22
-
(2011)
Nat Cell Biol
, vol.13
, Issue.3
, pp. 215-222
-
-
Efe, J.A.1
Hilcove, S.2
Kim, J.3
Zhou, H.4
Ouyang, K.5
Wang, G.6
-
20
-
-
84864542080
-
Drug screening for ALS using patient-specific induced pluripotent stem cells
-
Egawa N, Kitaoka S, Tsukita K, Naitoh M, Takahashi K, Yamamoto T. Drug screening for ALS using patient-specific induced pluripotent stem cells. Sci Transl Med. 2012 ; 4 (145). 145ra104
-
(2012)
Sci Transl Med
, vol.4
, Issue.145
-
-
Egawa, N.1
Kitaoka, S.2
Tsukita, K.3
Naitoh, M.4
Takahashi, K.5
Yamamoto, T.6
-
21
-
-
78149314205
-
Specification and morphogenesis of astrocytes
-
Freeman MR. Specification and morphogenesis of astrocytes. Science. 2010 ; 330 (6005). 774-8
-
(2010)
Science
, vol.330
, Issue.6005
, pp. 774-778
-
-
Freeman, M.R.1
-
22
-
-
70450265981
-
Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome
-
Fusaki N, Ban H, Nishiyama A, Saeki K, Hasegawa M. Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome. Proc Jpn Acad Ser B Phys Biol Sci. 2009 ; 85 (8). 348-62
-
(2009)
Proc Jpn Acad ser B Phys Biol Sci
, vol.85
, Issue.8
, pp. 348-362
-
-
Fusaki, N.1
Ban, H.2
Nishiyama, A.3
Saeki, K.4
Hasegawa, M.5
-
23
-
-
70349106392
-
Generation of cortical neurons from mouse embryonic stem cells
-
Gaspard N, Bouschet T, Herpoel A, Naeije G, van den Ameele J, Vanderhaeghen P. Generation of cortical neurons from mouse embryonic stem cells. Nat Protoc. 2009 ; 4 (10). 1454-63
-
(2009)
Nat Protoc
, vol.4
, Issue.10
, pp. 1454-1463
-
-
Gaspard, N.1
Bouschet, T.2
Herpoel, A.3
Naeije, G.4
Van Den Ameele, J.5
Vanderhaeghen, P.6
-
24
-
-
52149102948
-
An intrinsic mechanism of corticogenesis from embryonic stem cells
-
Gaspard N, Bouschet T, Hourez R, Dimidschstein J, Naeije G, van den Ameele J. An intrinsic mechanism of corticogenesis from embryonic stem cells. Nature. 2008 ; 455 (7211). 351-7
-
(2008)
Nature
, vol.455
, Issue.7211
, pp. 351-357
-
-
Gaspard, N.1
Bouschet, T.2
Hourez, R.3
Dimidschstein, J.4
Naeije, G.5
Van Den Ameele, J.6
-
25
-
-
79952899995
-
Methods for making induced pluripotent stem cells: Reprogramming a la carte
-
Gonzalez F, Boue S, Izpisua Belmonte JC. Methods for making induced pluripotent stem cells: reprogramming a la carte. Nat Rev Genet. 2011 ; 12 (4). 231-42
-
(2011)
Nat Rev Genet
, vol.12
, Issue.4
, pp. 231-242
-
-
Gonzalez, F.1
Boue, S.2
Izpisua Belmonte, J.C.3
-
26
-
-
79952258224
-
Somatic coding mutations in human induced pluripotent stem cells
-
Gore A, Li Z, Fung HL, Young JE, Agarwal S, Antosiewicz-Bourget J. Somatic coding mutations in human induced pluripotent stem cells. Nature. 2011 ; 471 (7336). 63-7
-
(2011)
Nature
, vol.471
, Issue.7336
, pp. 63-67
-
-
Gore, A.1
Li, Z.2
Fung, H.L.3
Young, J.E.4
Agarwal, S.5
Antosiewicz-Bourget, J.6
-
27
-
-
82455199147
-
Induced pluripotent stem cells - Opportunities for disease modelling and drug discovery
-
Grskovic M, Javaherian A, Strulovici B, Daley GQ. Induced pluripotent stem cells - opportunities for disease modelling and drug discovery. Nat Rev Drug Discov. 2011 ; 10 (12). 915-29
-
(2011)
Nat Rev Drug Discov
, vol.10
, Issue.12
, pp. 915-929
-
-
Grskovic, M.1
Javaherian, A.2
Strulovici, B.3
Daley, G.Q.4
-
28
-
-
0000331391
-
Adult frogs derived from the nuclei of single somatic cells
-
Gurdon JB. Adult frogs derived from the nuclei of single somatic cells. Dev Biol. 1962 ; 4: 256-73
-
(1962)
Dev Biol
, vol.4
, pp. 256-273
-
-
Gurdon, J.B.1
-
29
-
-
77957670482
-
Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats
-
Hargus G, Cooper O, Deleidi M, Levy A, Lee K, Marlow E. Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats. Proc Natl Acad Sci U S A. 2010 ; 107 (36). 15921-6
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.36
, pp. 15921-15926
-
-
Hargus, G.1
Cooper, O.2
Deleidi, M.3
Levy, A.4
Lee, K.5
Marlow, E.6
-
30
-
-
77952948707
-
Directing astroglia from the cerebral cortex into subtype specific functional neurons
-
Heinrich C, Blum R, Gascon S, Masserdotti G, Tripathi P, Sanchez R. Directing astroglia from the cerebral cortex into subtype specific functional neurons. PLoS Biol. 2010 ; 8 (5). e1000373
-
(2010)
PLoS Biol
, vol.8
, Issue.5
, pp. 1000373
-
-
Heinrich, C.1
Blum, R.2
Gascon, S.3
Masserdotti, G.4
Tripathi, P.5
Sanchez, R.6
-
31
-
-
42949175821
-
Identification of positionally distinct astrocyte subtypes whose identities are specified by a homeodomain code
-
Hochstim C, Deneen B, Lukaszewicz A, Zhou Q, Anderson DJ. Identification of positionally distinct astrocyte subtypes whose identities are specified by a homeodomain code. Cell. 2008 ; 133 (3). 510-22
-
(2008)
Cell
, vol.133
, Issue.3
, pp. 510-522
-
-
Hochstim, C.1
Deneen, B.2
Lukaszewicz, A.3
Zhou, Q.4
Anderson, D.J.5
-
32
-
-
79960836456
-
Genetic engineering of human pluripotent cells using TALE nucleases
-
Hockemeyer D, Wang H, Kiani S, Lai CS, Gao Q, Cassady JP. Genetic engineering of human pluripotent cells using TALE nucleases. Nat Biotechnol. 2011 ; 29 (8). 731-4
-
(2011)
Nat Biotechnol
, vol.29
, Issue.8
, pp. 731-734
-
-
Hockemeyer, D.1
Wang, H.2
Kiani, S.3
Lai, C.S.4
Gao, Q.5
Cassady, J.P.6
-
33
-
-
77749279749
-
Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency
-
Hu BY, Weick JP, Yu J, Ma LX, Zhang XQ, Thomson JA. Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency. Proc Natl Acad Sci U S A. 2010 ; 107 (9). 4335-40
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.9
, pp. 4335-4340
-
-
Hu, B.Y.1
Weick, J.P.2
Yu, J.3
Ma, L.X.4
Zhang, X.Q.5
Thomson, J.A.6
-
34
-
-
79952126043
-
Copy number variation and selection during reprogramming to pluripotency
-
Hussein SM, Batada NN, Vuoristo S, Ching RW, Autio R, Narva E. Copy number variation and selection during reprogramming to pluripotency. Nature. 2011 ; 471 (7336). 58-62
-
(2011)
Nature
, vol.471
, Issue.7336
, pp. 58-62
-
-
Hussein, S.M.1
Batada, N.N.2
Vuoristo, S.3
Ching, R.W.4
Autio, R.5
Narva, E.6
-
35
-
-
84873569333
-
Genome damage in induced pluripotent stem cells: Assessing the mechanisms and their consequences
-
Hussein SM, Elbaz J, Nagy AA. Genome damage in induced pluripotent stem cells: Assessing the mechanisms and their consequences. Bioessays. 2013 ; 35 (3). 152-62
-
(2013)
Bioessays
, vol.35
, Issue.3
, pp. 152-162
-
-
Hussein, S.M.1
Elbaz, J.2
Nagy, A.A.3
-
36
-
-
84856956771
-
Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells
-
Israel MA, Yuan SH, Bardy C, Reyna SM, Mu Y, Herrera C. Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells. Nature. 2012 ; 482 (7384). 216-20
-
(2012)
Nature
, vol.482
, Issue.7384
, pp. 216-220
-
-
Israel, M.A.1
Yuan, S.H.2
Bardy, C.3
Reyna, S.M.4
Mu, Y.5
Herrera, C.6
-
37
-
-
84867353088
-
Reprogramming of pericyte-derived cells of the adult human brain into induced neuronal cells
-
Karow M, Sanchez R, Schichor C, Masserdotti G, Ortega F, Heinrich C. Reprogramming of pericyte-derived cells of the adult human brain into induced neuronal cells. Cell Stem Cell. 2012 ; 11 (4). 471-6
-
(2012)
Cell Stem Cell
, vol.11
, Issue.4
, pp. 471-476
-
-
Karow, M.1
Sanchez, R.2
Schichor, C.3
Masserdotti, G.4
Ortega, F.5
Heinrich, C.6
-
38
-
-
0033638174
-
Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity
-
Kawasaki H, Mizuseki K, Nishikawa S, Kaneko S, Kuwana Y, Nakanishi S. Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity. Neuron. 2000 ; 28 (1). 31-40
-
(2000)
Neuron
, vol.28
, Issue.1
, pp. 31-40
-
-
Kawasaki, H.1
Mizuseki, K.2
Nishikawa, S.3
Kaneko, S.4
Kuwana, Y.5
Nakanishi, S.6
-
39
-
-
79956357347
-
Direct reprogramming of mouse fibroblasts to neural progenitors
-
Kim J, Efe JA, Zhu S, Talantova M, Yuan X, Wang S. Direct reprogramming of mouse fibroblasts to neural progenitors. Proc Natl Acad Sci U S A. 2011a ; 108 (19). 7838-43
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, Issue.19
, pp. 7838-7843
-
-
Kim, J.1
Efe, J.A.2
Zhu, S.3
Talantova, M.4
Yuan, X.5
Wang, S.6
-
40
-
-
80755129026
-
Functional integration of dopaminergic neurons directly converted from mouse fibroblasts
-
Kim J, Su SC, Wang H, Cheng AW, Cassady JP, Lodato MA. Functional integration of dopaminergic neurons directly converted from mouse fibroblasts. Cell Stem Cell. 2011b ; 9 (5). 413-9
-
(2011)
Cell Stem Cell
, vol.9
, Issue.5
, pp. 413-419
-
-
Kim, J.1
Su, S.C.2
Wang, H.3
Cheng, A.W.4
Cassady, J.P.5
Lodato, M.A.6
-
41
-
-
84355166561
-
Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease
-
Kriks S, Shim JW, Piao J, Ganat YM, Wakeman DR, Xie Z. Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease. Nature. 2011 ; 480 (7378). 547-51
-
(2011)
Nature
, vol.480
, Issue.7378
, pp. 547-551
-
-
Kriks, S.1
Shim, J.W.2
Piao, J.3
Ganat, Y.M.4
Wakeman, D.R.5
Xie, Z.6
-
42
-
-
84870063669
-
Acquired cancer stem cell phenotypes through Oct4-mediated dedifferentiation
-
Kumar SM, Liu S, Lu H, Zhang H, Zhang PJ, Gimotty PA. Acquired cancer stem cell phenotypes through Oct4-mediated dedifferentiation. Oncogene. 2012 ; 31 (47). 4898-911
-
(2012)
Oncogene
, vol.31
, Issue.47
, pp. 4898-4911
-
-
Kumar, S.M.1
Liu, S.2
Lu, H.3
Zhang, H.4
Zhang, P.J.5
Gimotty, P.A.6
-
43
-
-
78650971216
-
Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture
-
Laurent LC, Ulitsky I, Slavin I, Tran H, Schork A, Morey R. Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture. Cell Stem Cell. 2011 ; 8 (1). 106-18
-
(2011)
Cell Stem Cell
, vol.8
, Issue.1
, pp. 106-118
-
-
Laurent, L.C.1
Ulitsky, I.2
Slavin, I.3
Tran, H.4
Schork, A.5
Morey, R.6
-
44
-
-
70349301819
-
Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs
-
Lee G, Papapetrou EP, Kim H, Chambers SM, Tomishima MJ, Fasano CA. Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs. Nature. 2009 ; 461 (7262). 402-6
-
(2009)
Nature
, vol.461
, Issue.7262
, pp. 402-406
-
-
Lee, G.1
Papapetrou, E.P.2
Kim, H.3
Chambers, S.M.4
Tomishima, M.J.5
Fasano, C.A.6
-
45
-
-
84857136772
-
Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells
-
Lujan E, Chanda S, Ahlenius H, Sudhof TC, Wernig M. Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells. Proc Natl Acad Sci U S A. 2012 ; 109 (7). 2527-32
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, Issue.7
, pp. 2527-2532
-
-
Lujan, E.1
Chanda, S.2
Ahlenius, H.3
Sudhof, T.C.4
Wernig, M.5
-
46
-
-
77957334627
-
Identification and classification of chromosomal aberrations in human induced pluripotent stem cells
-
Mayshar Y, Ben-David U, Lavon N, Biancotti JC, Yakir B, Clark AT. Identification and classification of chromosomal aberrations in human induced pluripotent stem cells. Cell Stem Cell. 2010 ; 7 (4). 521-31
-
(2010)
Cell Stem Cell
, vol.7
, Issue.4
, pp. 521-531
-
-
Mayshar, Y.1
Ben-David, U.2
Lavon, N.3
Biancotti, J.C.4
Yakir, B.5
Clark, A.T.6
-
47
-
-
35148845584
-
Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells
-
Meissner A, Wernig M, Jaenisch R. Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells. Nat Biotechnol. 2007 ; 25 (10). 1177-81
-
(2007)
Nat Biotechnol
, vol.25
, Issue.10
, pp. 1177-1181
-
-
Meissner, A.1
Wernig, M.2
Jaenisch, R.3
-
48
-
-
77950651133
-
High-resolution DNA analysis of human embryonic stem cell lines reveals culture-induced copy number changes and loss of heterozygosity
-
Narva E, Autio R, Rahkonen N, Kong L, Harrison N, Kitsberg D. High-resolution DNA analysis of human embryonic stem cell lines reveals culture-induced copy number changes and loss of heterozygosity. Nat Biotechnol. 2010 ; 28 (4). 371-7
-
(2010)
Nat Biotechnol
, vol.28
, Issue.4
, pp. 371-377
-
-
Narva, E.1
Autio, R.2
Rahkonen, N.3
Kong, L.4
Harrison, N.5
Kitsberg, D.6
-
49
-
-
84871631622
-
Pluripotent cells in farm animals: State of the art and future perspectives
-
Nowak-Imialek M, Niemann H. Pluripotent cells in farm animals: state of the art and future perspectives. Reprod Fertil Dev. 2012 ; 25 (1). 103-28
-
(2012)
Reprod Fertil Dev
, vol.25
, Issue.1
, pp. 103-128
-
-
Nowak-Imialek, M.1
Niemann, H.2
-
50
-
-
70449643154
-
Advances in stem cell research for amyotrophic lateral sclerosis
-
Papadeas ST, Maragakis NJ. Advances in stem cell research for amyotrophic lateral sclerosis. Curr Opin Biotechnol. 2009 ; 20 (5). 545-51
-
(2009)
Curr Opin Biotechnol
, vol.20
, Issue.5
, pp. 545-551
-
-
Papadeas, S.T.1
Maragakis, N.J.2
-
51
-
-
50549089957
-
Disease-specific induced pluripotent stem cells
-
Park IH, Arora N, Huo H, Maherali N, Ahfeldt T, Shimamura A. Disease-specific induced pluripotent stem cells. Cell. 2008 ; 134 (5). 877-86
-
(2008)
Cell
, vol.134
, Issue.5
, pp. 877-886
-
-
Park, I.H.1
Arora, N.2
Huo, H.3
Maherali, N.4
Ahfeldt, T.5
Shimamura, A.6
-
52
-
-
4344592974
-
Derivation of midbrain dopamine neurons from human embryonic stem cells
-
Perrier AL, Tabar V, Barberi T, Rubio ME, Bruses J, Topf N. Derivation of midbrain dopamine neurons from human embryonic stem cells. Proc Natl Acad Sci U S A. 2004 ; 101 (34). 12543-8
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, Issue.34
, pp. 12543-12548
-
-
Perrier, A.L.1
Tabar, V.2
Barberi, T.3
Rubio, M.E.4
Bruses, J.5
Topf, N.6
-
53
-
-
79959951387
-
Direct conversion of human fibroblasts to dopaminergic neurons
-
Pfisterer U, Kirkeby A, Torper O, Wood J, Nelander J, Dufour A. Direct conversion of human fibroblasts to dopaminergic neurons. Proc Natl Acad Sci U S A. 2011 ; 108 (25). 10343-8
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, Issue.25
, pp. 10343-10348
-
-
Pfisterer, U.1
Kirkeby, A.2
Torper, O.3
Wood, J.4
Nelander, J.5
Dufour, A.6
-
54
-
-
84855397933
-
Concise review: Embryonic stem cells versus induced pluripotent stem cells: The game is on
-
Puri MC, Nagy A. Concise review: embryonic stem cells versus induced pluripotent stem cells: the game is on. Stem Cells. 2012 ; 30 (1). 10-4
-
(2012)
Stem Cells
, vol.30
, Issue.1
, pp. 10-14
-
-
Puri, M.C.1
Nagy, A.2
-
55
-
-
84856007232
-
The promise of induced pluripotent stem cells in research and therapy
-
Robinton DA, Daley GQ. The promise of induced pluripotent stem cells in research and therapy. Nature. 2012 ; 481 (7381). 295-305
-
(2012)
Nature
, vol.481
, Issue.7381
, pp. 295-305
-
-
Robinton, D.A.1
Daley, G.Q.2
-
56
-
-
30144442965
-
KLF4, p21 and context-dependent opposing forces in cancer
-
Rowland BD, Peeper DS. KLF4, p21 and context-dependent opposing forces in cancer. Nat Rev Cancer. 2006 ; 6 (1). 11-23
-
(2006)
Nat Rev Cancer
, vol.6
, Issue.1
, pp. 11-23
-
-
Rowland, B.D.1
Peeper, D.S.2
-
57
-
-
70450285340
-
Technical challenges in using human induced pluripotent stem cells to model disease
-
Saha K, Jaenisch R. Technical challenges in using human induced pluripotent stem cells to model disease. Cell Stem Cell. 2009 ; 5 (6). 584-95
-
(2009)
Cell Stem Cell
, vol.5
, Issue.6
, pp. 584-595
-
-
Saha, K.1
Jaenisch, R.2
-
58
-
-
84860510280
-
Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease
-
Sanchez-Danes A, Richaud-Patin Y, Carballo-Carbajal I, Jimenez-Delgado S, Caig C, Mora S. Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease. EMBO Mol Med. 2012 ; 4 (5). 380-95
-
(2012)
EMBO Mol Med
, vol.4
, Issue.5
, pp. 380-395
-
-
Sanchez-Danes, A.1
Richaud-Patin, Y.2
Carballo-Carbajal, I.3
Jimenez-Delgado, S.4
Caig, C.5
Mora, S.6
-
59
-
-
84862778046
-
Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses
-
S1-86
-
Shi Y, Kirwan P, Smith J, Robinson HP, Livesey FJ. Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses. Nat Neurosci. 2012 ; 15 (3). 477 S1-86
-
(2012)
Nat Neurosci
, vol.15
, Issue.3
, pp. 477
-
-
Shi, Y.1
Kirwan, P.2
Smith, J.3
Robinson, H.P.4
Livesey, F.J.5
-
60
-
-
61349100729
-
Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors
-
Soldner F, Hockemeyer D, Beard C, Gao Q, Bell GW, Cook EG. Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors. Cell. 2009 ; 136 (5). 964-77
-
(2009)
Cell
, vol.136
, Issue.5
, pp. 964-977
-
-
Soldner, F.1
Hockemeyer, D.2
Beard, C.3
Gao, Q.4
Bell, G.W.5
Cook, E.G.6
-
61
-
-
80052295767
-
Conversion of mouse and human fibroblasts into functional spinal motor neurons
-
Son EY, Ichida JK, Wainger BJ, Toma JS, Rafuse VF, Woolf CJ. Conversion of mouse and human fibroblasts into functional spinal motor neurons. Cell Stem Cell. 2011 ; 9 (3). 205-18
-
(2011)
Cell Stem Cell
, vol.9
, Issue.3
, pp. 205-218
-
-
Son, E.Y.1
Ichida, J.K.2
Wainger, B.J.3
Toma, J.S.4
Rafuse, V.F.5
Woolf, C.J.6
-
62
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell. 2007 ; 131 (5). 861-72
-
(2007)
Cell
, vol.131
, Issue.5
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
Narita, M.4
Ichisaka, T.5
Tomoda, K.6
-
63
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell. 2006 ; 126 (4). 663-76
-
(2006)
Cell
, vol.126
, Issue.4
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
64
-
-
84859555919
-
Direct conversion of fibroblasts into stably expandable neural stem cells
-
Thier M, Worsdorfer P, Lakes YB, Gorris R, Herms S, Opitz T. Direct conversion of fibroblasts into stably expandable neural stem cells. Cell Stem Cell. 2012 ; 10 (4). 473-9
-
(2012)
Cell Stem Cell
, vol.10
, Issue.4
, pp. 473-479
-
-
Thier, M.1
Worsdorfer, P.2
Lakes, Y.B.3
Gorris, R.4
Herms, S.5
Opitz, T.6
-
65
-
-
0032491416
-
Embryonic stem cell lines derived from human blastocysts
-
Thomson JA, Itskovitz-Eldor J, Shapiro SS, Waknitz MA, Swiergiel JJ, Marshall VS. Embryonic stem cell lines derived from human blastocysts. Science. 1998 ; 282 (5391). 1145-7
-
(1998)
Science
, vol.282
, Issue.5391
, pp. 1145-1147
-
-
Thomson, J.A.1
Itskovitz-Eldor, J.2
Shapiro, S.S.3
Waknitz, M.A.4
Swiergiel, J.J.5
Marshall, V.S.6
-
66
-
-
77649162059
-
Direct conversion of fibroblasts to functional neurons by defined factors
-
Vierbuchen T, Ostermeier A, Pang ZP, Kokubu Y, Sudhof TC, Wernig M. Direct conversion of fibroblasts to functional neurons by defined factors. Nature. 2010 ; 463 (7284). 1035-41
-
(2010)
Nature
, vol.463
, Issue.7284
, pp. 1035-1041
-
-
Vierbuchen, T.1
Ostermeier, A.2
Pang, Z.P.3
Kokubu, Y.4
Sudhof, T.C.5
Wernig, M.6
-
67
-
-
14544296563
-
Directed differentiation of telencephalic precursors from embryonic stem cells
-
Watanabe K, Kamiya D, Nishiyama A, Katayama T, Nozaki S, Kawasaki H. Directed differentiation of telencephalic precursors from embryonic stem cells. Nat Neurosci. 2005 ; 8 (3). 288-96
-
(2005)
Nat Neurosci
, vol.8
, Issue.3
, pp. 288-296
-
-
Watanabe, K.1
Kamiya, D.2
Nishiyama, A.3
Katayama, T.4
Nozaki, S.5
Kawasaki, H.6
-
68
-
-
42649130264
-
Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease
-
Wernig M, Zhao JP, Pruszak J, Hedlund E, Fu D, Soldner F. Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease. Proc Natl Acad Sci U S A. 2008 ; 105 (15). 5856-61
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.15
, pp. 5856-5861
-
-
Wernig, M.1
Zhao, J.P.2
Pruszak, J.3
Hedlund, E.4
Fu, D.5
Soldner, F.6
-
69
-
-
0037047320
-
Directed differentiation of embryonic stem cells into motor neurons
-
Wichterle H, Lieberam I, Porter JA, Jessell TM. Directed differentiation of embryonic stem cells into motor neurons. Cell. 2002 ; 110 (3). 385-97
-
(2002)
Cell
, vol.110
, Issue.3
, pp. 385-397
-
-
Wichterle, H.1
Lieberam, I.2
Porter, J.A.3
Jessell, T.M.4
-
70
-
-
0031044215
-
Viable offspring derived from fetal and adult mammalian cells
-
Wilmut I, Schnieke AE, McWhir J, Kind AJ, Campbell KH. Viable offspring derived from fetal and adult mammalian cells. Nature. 1997 ; 385 (6619). 810-3
-
(1997)
Nature
, vol.385
, Issue.6619
, pp. 810-813
-
-
Wilmut, I.1
Schnieke, A.E.2
McWhir, J.3
Kind, A.J.4
Campbell, K.H.5
-
71
-
-
64749083939
-
PiggyBac transposition reprograms fibroblasts to induced pluripotent stem cells
-
Woltjen K, Michael IP, Mohseni P, Desai R, Mileikovsky M, Hamalainen R. piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells. Nature. 2009 ; 458 (7239). 766-70
-
(2009)
Nature
, vol.458
, Issue.7239
, pp. 766-770
-
-
Woltjen, K.1
Michael, I.P.2
Mohseni, P.3
Desai, R.4
Mileikovsky, M.5
Hamalainen, R.6
-
72
-
-
2542455620
-
Stepwise reprogramming of B cells into macrophages
-
Xie H, Ye M, Feng R, Graf T. Stepwise reprogramming of B cells into macrophages. Cell. 2004 ; 117 (5). 663-76
-
(2004)
Cell
, vol.117
, Issue.5
, pp. 663-676
-
-
Xie, H.1
Ye, M.2
Feng, R.3
Graf, T.4
-
73
-
-
81255169342
-
Modeling familial Alzheimer's disease with induced pluripotent stem cells
-
Yagi T, Ito D, Okada Y, Akamatsu W, Nihei Y, Yoshizaki T. Modeling familial Alzheimer's disease with induced pluripotent stem cells. Hum Mol Genet. 2011 ; 20 (23). 4530-9
-
(2011)
Hum Mol Genet
, vol.20
, Issue.23
, pp. 4530-4539
-
-
Yagi, T.1
Ito, D.2
Okada, Y.3
Akamatsu, W.4
Nihei, Y.5
Yoshizaki, T.6
-
74
-
-
0037313844
-
Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture
-
Ying QL, Stavridis M, Griffiths D, Li M, Smith A. Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture. Nat Biotechnol. 2003 ; 21 (2). 183-6
-
(2003)
Nat Biotechnol
, vol.21
, Issue.2
, pp. 183-186
-
-
Ying, Q.L.1
Stavridis, M.2
Griffiths, D.3
Li, M.4
Smith, A.5
-
75
-
-
65649116572
-
Human induced pluripotent stem cells free of vector and transgene sequences
-
Yu J, Hu K, Smuga-Otto K, Tian S, Stewart R, Slukvin. Human induced pluripotent stem cells free of vector and transgene sequences. Science. 2009 ; 324 (5928). 797-801
-
(2009)
Science
, vol.324
, Issue.5928
, pp. 797-801
-
-
Yu, J.1
Hu, K.2
Smuga-Otto, K.3
Tian, S.4
Stewart, R.5
Slukvin6
-
76
-
-
36749043230
-
Induced pluripotent stem cell lines derived from human somatic cells
-
Yu J, Vodyanik MA, Smuga-Otto K, Antosiewicz-Bourget J, Frane JL, Tian S. Induced pluripotent stem cell lines derived from human somatic cells. Science. 2007 ; 318 (5858). 1917-20
-
(2007)
Science
, vol.318
, Issue.5858
, pp. 1917-1920
-
-
Yu, J.1
Vodyanik, M.A.2
Smuga-Otto, K.3
Antosiewicz-Bourget, J.4
Frane, J.L.5
Tian, S.6
-
77
-
-
53349178722
-
In vivo reprogramming of adult pancreatic exocrine cells to beta-cells
-
Zhou Q, Brown J, Kanarek A, Rajagopal J, Melton DA. In vivo reprogramming of adult pancreatic exocrine cells to beta-cells. Nature. 2008 ; 455 (7213). 627-32
-
(2008)
Nature
, vol.455
, Issue.7213
, pp. 627-632
-
-
Zhou, Q.1
Brown, J.2
Kanarek, A.3
Rajagopal, J.4
Melton, D.A.5
-
78
-
-
67649170378
-
Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells
-
Zou J, Maeder ML, Mali P, Pruett-Miller SM, Thibodeau-Beganny S, Chou BK. Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Cell Stem Cell. 2009 ; 5 (1). 97-110
-
(2009)
Cell Stem Cell
, vol.5
, Issue.1
, pp. 97-110
-
-
Zou, J.1
Maeder, M.L.2
Mali, P.3
Pruett-Miller, S.M.4
Thibodeau-Beganny, S.5
Chou, B.K.6
|