High-resolution DNA analysis of human embryonic stem cell lines reveals culture-induced copy number changes and loss of heterozygosity

Nature Biotechnology

Volumn 28, Issue 4, 2010, Pages 371-377

  Närvä, Elisa ^a   Autio, Reija ^a,b   Rahkonen, Nelly ^a   Kong, Lingjia ^b   Harrison, Neil ^c   Kitsberg, Danny ^d   Borghese, Lodovica ^e   Itskovitz Eldor, Joseph ^f   Rasool, Omid ^a   Dvorak, Petr ^g   Hovatta, Outi ^h   Otonkoski, Timo ⁱ   Tuuri, Timo ⁱ   Cui, Wei ^j   Brüstle, Oliver ^e   Baker, Duncan ^k   Maltby, Edna ^k   Moore, Harry D ^c   Benvenisty, Nissim ^l   Andrews, Peter W ^c   Yli Harja, Olli ^b,m   Lahesmaa, Riitta ^a   more..

^a UNIVERSITY OF TURKU   (Finland)

^b TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^c UNIVERSITY OF SHEFFIELD   (United Kingdom)

^d Stem Cell Technologies Ltd   (Israel)

^e UNIVERSITY OF BONN   (Germany)

^f TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^g MASARYK UNIVERSITY   (Czech Republic)

^h KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

ⁱ UNIVERSITY OF HELSINKI   (Finland)

^j IMPERIAL COLLEGE LONDON   (United Kingdom)

^k SHEFFIELD CHILDREN'S NHS FOUNDATION TRUST   (United Kingdom)

^l HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^m INSTITUTE FOR SYSTEMS BIOLOGY   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

AFFYMETRIX; CHROMOSOMAL ABNORMALITIES; COPY NUMBER; DNA ANALYSIS; GENETIC ANALYSIS; HETEROZYGOSITY; HIGH RESOLUTION; HUMAN EMBRYONIC STEM CELLS; SINGLE NUCLEOTIDE POLYMORPHISMS;

CELL GROWTH; GENE EXPRESSION; PROBES; STEM CELLS;

CELL CULTURE;

ARTICLE; CELL CULTURE; CELL LINE; CHROMOSOME 16; DNA DETERMINATION; EMBRYONIC STEM CELL; GENE AMPLIFICATION; GENE NUMBER; GENETIC ANALYSIS; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

BASE SEQUENCE; CELL CULTURE TECHNIQUES; DNA; DNA COPY NUMBER VARIATIONS; DNA MUTATIONAL ANALYSIS; EMBRYONIC STEM CELLS; GENETIC VARIATION; HUMANS; MOLECULAR SEQUENCE DATA; SEQUENCE ANALYSIS, DNA;

EID: 77950651133     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt.1615     Document Type: Article

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