Involvement of organic cation transporter 1 in hepatic and intestinal distribution of metformin

Journal of Pharmacology and Experimental Therapeutics

Volumn 302, Issue 2, 2002, Pages 510-515

  Wang, De Sheng ^a,b,c   Jonker, Johan W ^a,b,c   Kato, Yukio ^a,b,c   Kusuhara, Hiroyuki ^a,b,c   Schinkel, Alfred H ^a,b,c   Sugiyama, Yuichi ^a,b,c  

^a UNIVERSITY OF TOKYO   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BIGUANIDE DERIVATIVE; BUFORMIN; CARRIER PROTEIN; CATION; CIMETIDINE; METFORMIN; ORGANIC CATION TRANSPORTER; PHENFORMIN; UNCLASSIFIED DRUG;

ADOLESCENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CHO CELL; CONTROLLED STUDY; DRUG CLEARANCE; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG TRANSPORT; DRUG UPTAKE; FEMALE; INTESTINE; KNOCKOUT MOUSE; LIVER; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSPORT KINETICS; URINARY EXCRETION;

ANIMALS; BIOLOGICAL TRANSPORT; CHO CELLS; CIMETIDINE; CRICETINAE; INTESTINAL ABSORPTION; KINETICS; LIVER; METFORMIN; MICE; MICE, KNOCKOUT; ORGANIC CATION TRANSPORTER 1; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; TISSUE DISTRIBUTION; TRANSFECTION;

EID: 0036070666     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.102.034140     Document Type: Article

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