-
1
-
-
84857793524
-
Decisions about dendritic cells: Past, present, and future
-
Steinman RM. Decisions about dendritic cells: Past, present, and future. Annu. Rev. Immunol. 30, 1-22 (2012
-
(2012)
Annu. Rev. Immunol
, vol.30
, pp. 1-22
-
-
Steinman, R.M.1
-
2
-
-
0033009891
-
Selection of the T cell repertoire
-
Sebzda E, Mariathasan S, Ohteki T, Jones R, Bachmann MF, Ohashi PS. Selection of the T cell repertoire. Annu. Rev. Immunol. 17, 829-874 (1999
-
(1999)
Annu. Rev. Immunol
, vol.17
, pp. 829-874
-
-
Sebzda, E.1
Mariathasan, S.2
Ohteki, T.3
Jones, R.4
Bachmann, M.F.5
Ohashi, P.S.6
-
4
-
-
84869046998
-
Multiple Treg suppressive modules and their adaptability
-
Sakaguchi S. Multiple Treg suppressive modules and their adaptability. Front. Immunol. 1-6 (2012
-
(2012)
Front. Immunol
, pp. 1-6
-
-
Sakaguchi, S.1
-
5
-
-
84859416933
-
Regulatory t cells: Mechanisms of differentiation and function
-
Josefowicz SZ, Lu L-F, Rudensky AY. Regulatory T Cells: Mechanisms of Differentiation and Function. Ann. Rev. Immunol. 30(1), 531-564 (2012
-
(2012)
Ann. Rev. Immunol
, vol.30
, Issue.1
, pp. 531-564
-
-
Josefowicz, S.Z.1
Lu, L.-F.2
Rudensky, A.Y.3
-
6
-
-
34948906159
-
Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover
-
Almeida JR, Price DA, Papagno L et al. Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover. J. Exp. Med. 204(10), 2473-2485 (2007
-
(2007)
J. Exp. Med
, vol.204
, Issue.10
, pp. 2473-2485
-
-
Almeida, J.R.1
Price, D.A.2
Papagno, L.3
-
7
-
-
34250303350
-
Multifunctional th1 cells define a correlate of vaccine-mediated protection against leishmania major
-
Darrah PA, Patel DT, De Luca PM et al. Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major. Nat. Med. 13(7), 843-850 (2007
-
(2007)
Nat. Med
, vol.13
, Issue.7
, pp. 843-850
-
-
Darrah, P.A.1
Patel, D.T.2
De Luca, P.M.3
-
8
-
-
84862682110
-
The three main stumbling blocks for anticancer T cells
-
Baitsch L, Fuertes Marraco SA, Legat A, Meyer C, Speiser DE. The three main stumbling blocks for anticancer T cells. Trends Immunol. 33(7), 364-372 (2012
-
(2012)
Trends Immunol
, vol.33
, Issue.7
, pp. 364-372
-
-
Baitsch, L.1
Fuertes Marraco, S.A.2
Legat, A.3
Meyer, C.4
Speiser, D.E.5
-
9
-
-
0030954574
-
Antigens recognized by T-lymphocytes on human tumours
-
Coulie PG, Van den Eynde BJ, der Bruggen van P, Van Pel A, Boon T. Antigens recognized by T-lymphocytes on human tumours. Biochem. Soc. Trans. 25(2), 544-548 (1997
-
(1997)
Biochem. Soc. Trans
, vol.25
, Issue.2
, pp. 544-548
-
-
Coulie, P.G.1
Van Den Eynde, B.J.2
Der Bruggen Van, P.3
Van Pel, A.4
Boon, T.5
-
10
-
-
23144464171
-
Cancer/testis antigens, gametogenesis and cancer
-
Simpson AJG, Caballero OL, Jungbluth A, Chen Y-T, Old LJ. Cancer/testis antigens, gametogenesis and cancer. Nat. Rev. Cancer 5(8), 615-625 (2005
-
(2005)
Nat. Rev. Cancer
, vol.5
, Issue.8
, pp. 615-625
-
-
Simpson, A.J.G.1
Caballero, O.L.2
Jungbluth, A.3
Chen, Y.-T.4
Old, L.J.5
-
11
-
-
0030848578
-
Self antigens expressed by solid tumors Do not efficiently stimulate naive or activated T cells: Implications for immunotherapy
-
Speiser DE, Miranda R, Zakarian A et al. Self antigens expressed by solid tumors Do not efficiently stimulate naive or activated T cells: Implications for immunotherapy. J. Exp. Med. 186(5), 645-653 (1997
-
(1997)
J. Exp. Med
, vol.186
, Issue.5
, pp. 645-653
-
-
Speiser, D.E.1
Miranda, R.2
Zakarian, A.3
-
12
-
-
37849033441
-
Induction of MHC class I molecule cell surface expression and epigenetic activation of antigen-processing machinery components in a murine model for human papilloma virus 16-Associated tumours
-
Manning J, Indrova M, Lubyova B et al. Induction of MHC class I molecule cell surface expression and epigenetic activation of antigen-processing machinery components in a murine model for human papilloma virus 16-Associated tumours. Immunology 123(2), 218-227 (2008
-
(2008)
Immunology
, vol.123
, Issue.2
, pp. 218-227
-
-
Manning, J.1
Indrova, M.2
Lubyova, B.3
-
13
-
-
77953718827
-
Hard and soft lesions underlying the HLA class I alterations in cancer cells: Implications for immunotherapy
-
Garrido F, Cabrera T, Aptsiauri N. Hard and soft lesions underlying the HLA class I alterations in cancer cells: Implications for immunotherapy. Int. J. Cancer 127(2), 249-256 (2010
-
(2010)
Int. J. Cancer
, vol.127
, Issue.2
, pp. 249-256
-
-
Garrido, F.1
Cabrera, T.2
Aptsiauri, N.3
-
14
-
-
84856867834
-
Immunotherapy earns its spot in the ranks of cancer therapy
-
Pardoll D, Drake C. Immunotherapy earns its spot in the ranks of cancer therapy. J. Exp. Med. 209(2), 201-209 (2012
-
(2012)
J. Exp. Med
, vol.209
, Issue.2
, pp. 201-209
-
-
Pardoll, D.1
Drake, C.2
-
15
-
-
80053343794
-
The present and future of peptide vaccines for cancer
-
Slingluff CL Jr. The present and future of peptide vaccines for cancer. Cancer J. 17(5), 343-350 (2011
-
(2011)
Cancer J.
, vol.17
, Issue.5
, pp. 343-350
-
-
Slingluff Jr., C.L.1
-
16
-
-
0037058993
-
Adoptive T cell therapy using antigen-specific CD8+ T cell clones for the treatment of patients with metastatic melanoma: In vivo persistence, migration, and antitumor effect of transferred T cells
-
Yee C, Thompson JA, Byrd D et al. Adoptive T cell therapy using antigen-specific CD8+ T cell clones for the treatment of patients with metastatic melanoma: In vivo persistence, migration, and antitumor effect of transferred T cells. Proc. Natl Acad. Sci. USA 99(25), 16168-16173 (2002
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, Issue.25
, pp. 16168-16173
-
-
Yee, C.1
Thompson, J.A.2
Byrd, D.3
-
17
-
-
70449474686
-
A distinct subset of self-renewing human memory CD8+ T Cells survives cytotoxic chemotherapy
-
Turtle CJ, Swanson HM, Fujii N, Estey EH, Riddell SR. A distinct subset of self-renewing human memory CD8+ T Cells survives cytotoxic chemotherapy. Immunity 31(5), 834-844 (2009
-
(2009)
Immunity
, vol.31
, Issue.5
, pp. 834-844
-
-
Turtle, C.J.1
Swanson, H.M.2
Fujii, N.3
Estey, E.H.4
Riddell, S.R.5
-
18
-
-
78649756275
-
Expansion and characterization of human melanoma tumor-infiltrating lymphocytes (TILs
-
Nguyen LT, Yen PH, Nie J et al. Expansion and characterization of human melanoma tumor-infiltrating lymphocytes (TILs). PLoS ONE 5(11), e13940 (2010
-
(2010)
PLoS ONE
, vol.5
, Issue.11
-
-
Nguyen, L.T.1
Yen, P.H.2
Nie, J.3
-
19
-
-
79955373860
-
Establishment of antitumor memory in humans using in vitro-educated CD8+ T Cells
-
Butler MO, Friedlander P, Milstein MI et al. Establishment of antitumor memory in humans using in vitro-educated CD8+ T Cells. Sci. Transl. Med. 3(80), 80ra34-80ra34 (2011
-
(2011)
Sci. Transl. Med
, vol.3
, Issue.80
-
-
Butler, M.O.1
Friedlander, P.2
Milstein, M.I.3
-
20
-
-
79960299888
-
Durable complete responses in heavily pretreated patients with metastatic melanoma using T-Cell transfer immunotherapy
-
Rosenberg SA, Yang JC, Sherry RM et al. Durable complete responses in heavily pretreated patients with metastatic melanoma using T-Cell transfer immunotherapy. Clin. Cancer Res. 17(13), 4550-4557 (2011
-
(2011)
Clin. Cancer Res
, vol.17
, Issue.13
, pp. 4550-4557
-
-
Rosenberg, S.A.1
Yang, J.C.2
Sherry, R.M.3
-
21
-
-
77949475175
-
Overview of gene therapy clinical progress including cancer treatment with gene-modified T cells
-
Brenner MK, Okur FV. Overview of gene therapy clinical progress including cancer treatment with gene-modified T cells. Hematol.Am. Soc. Hematol. Educ. Program 675-681 (2009
-
(2009)
Hematol. Am. Soc. Hematol. Educ. Program
, pp. 675-681
-
-
Brenner, M.K.1
Okur, F.V.2
-
23
-
-
79960008541
-
Prospects and limitations of T cell receptor gene therapy
-
Jorritsma A, Schotte R, Coccoris M, de Witte MA, Schumacher TNM. Prospects and limitations of T cell receptor gene therapy. Curr. Gene. Ther. 11(4), 276-287 (2011
-
(2011)
Curr. Gene. Ther
, vol.11
, Issue.4
, pp. 276-287
-
-
Jorritsma, A.1
Schotte, R.2
Coccoris, M.3
De Witte, M.A.4
Schumacher, T.N.M.5
-
24
-
-
80054680991
-
Treating cancer with genetically engineered T cells
-
Park TS, Rosenberg SA, Morgan RA. Treating cancer with genetically engineered T cells. Trends Biotechnol. 29(11), 550-557 (2011
-
(2011)
Trends Biotechnol
, vol.29
, Issue.11
, pp. 550-557
-
-
Park, T.S.1
Rosenberg, S.A.2
Morgan, R.A.3
-
25
-
-
84862902493
-
Challenges in T cell receptor gene therapy
-
Uttenthal BJ, Chua I, Morris EC, Stauss HJ. Challenges in T cell receptor gene therapy. J. Gene. Med. 14(6), 386-399 (2012
-
(2012)
J. Gene. Med
, vol.14
, Issue.6
, pp. 386-399
-
-
Uttenthal, B.J.1
Chua, I.2
Morris, E.C.3
Stauss, H.J.4
-
26
-
-
84875151508
-
T cell-based gene therapy of cancer
-
Gill S, Kalos M. T cell-based gene therapy of cancer. Transl. Res. 161(4), 365-379 (2013
-
(2013)
Transl. Res
, vol.161
, Issue.4
, pp. 365-379
-
-
Gill, S.1
Kalos, M.2
-
27
-
-
84883790660
-
Molecular insights for optimizing T cell receptor specificity against cancer
-
Hebeisen M, Oberle SG, Presotto D, Speiser DE, Zehn D, Rufer N. Molecular insights for optimizing T cell receptor specificity against cancer. Front. Immunol. 4, 154 (2013
-
(2013)
Front. Immunol
, vol.4
, Issue.154
-
-
Hebeisen, M.1
Oberle, S.G.2
Presotto, D.3
Speiser, D.E.4
Zehn, D.5
Rufer, N.6
-
28
-
-
67349193717
-
Adjuvant IL-7 antagonizes multiple cellular and molecular inhibitory networks to enhance immunotherapies
-
Pellegrini M, Calzascia T, Elford AR et al. Adjuvant IL-7 antagonizes multiple cellular and molecular inhibitory networks to enhance immunotherapies. Nat. Med. 15(5), 528-536 (2009
-
(2009)
Nat. Med
, vol.15
, Issue.5
, pp. 528-536
-
-
Pellegrini, M.1
Calzascia, T.2
Elford, A.R.3
-
29
-
-
77955280009
-
Fighting cancers from within: Augmenting tumor immunity with cytokine therapy
-
Pellegrini M, Mak TW, Ohashi PS. Fighting cancers from within: Augmenting tumor immunity with cytokine therapy. Trends Pharmacol. Sci. 31(8), 356-363 (2010
-
(2010)
Trends Pharmacol. Sci
, vol.31
, Issue.8
, pp. 356-363
-
-
Pellegrini, M.1
Mak, T.W.2
Ohashi, P.S.3
-
30
-
-
84869380716
-
Immunology beats cancer: A blueprint for successful translation
-
Pardoll DM. Immunology beats cancer: A blueprint for successful translation. Nat. Immunol. 13(12), 1129-1132 (2012
-
(2012)
Nat. Immunol
, vol.13
, Issue.12
, pp. 1129-1132
-
-
Pardoll, D.M.1
-
31
-
-
84862882003
-
Tumor immunotherapy directed at PD-1
-
Ribas A. Tumor immunotherapy directed at PD-1. N. Engl. J. Med. 366(26), 2517-2519 (2012
-
(2012)
N. Engl. J. Med
, vol.366
, Issue.26
, pp. 2517-2519
-
-
Ribas, A.1
-
32
-
-
84877896663
-
Targeting PD-1/ PD-L1 interactions for cancer immunotherapy
-
Zitvogel L, Kroemer G. Targeting PD-1/ PD-L1 interactions for cancer immunotherapy. OncoImmunology 1(8), 1223-1225 (2012
-
(2012)
OncoImmunology
, vol.1
, Issue.8
, pp. 1223-1225
-
-
Zitvogel, L.1
Kroemer, G.2
-
33
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi FS, O'Day SJ, McDermott DF et al. Improved survival with ipilimumab in patients with metastatic melanoma. N. Engl. J. Med. 363(8), 711-723 (2010
-
(2010)
N. Engl. J. Med
, vol.363
, Issue.8
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
-
34
-
-
79955002016
-
Transcriptome-wide studies of merkel cell carcinoma and validation of intratumoral CD8+ lymphocyte invasion as an independent predictor of survival
-
Paulson KG, Iyer JG, Tegeder AR et al. Transcriptome-wide studies of merkel cell carcinoma and validation of intratumoral CD8+ lymphocyte invasion as an independent predictor of survival. J. Clin. Oncol. 29(12), 1539-1546 (2011
-
(2011)
J. Clin. Oncol
, vol.29
, Issue.12
, pp. 1539-1546
-
-
Paulson, K.G.1
Iyer, J.G.2
Tegeder, A.R.3
-
35
-
-
84880369484
-
Clinical implications of CD8+ T-cell infiltration in frequent and rare cancers
-
Feldmeyer L, Gaide O, Speiser DE. Clinical implications of CD8+ T-cell infiltration in frequent and rare cancers. J. Investig. Dermatol. 133(8), 1929-1932 (2013
-
(2013)
J. Investig. Dermatol
, vol.133
, Issue.8
, pp. 1929-1932
-
-
Feldmeyer, L.1
Gaide, O.2
Speiser, D.E.3
-
36
-
-
0037448353
-
Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer
-
Zhang L, Conejo-Garcia JR, Katsaros D et al. Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer. N. Engl. J. Med. 348(3), 203-213 (2003
-
(2003)
N. Engl. J. Med
, vol.348
, Issue.3
, pp. 203-213
-
-
Zhang, L.1
Conejo-Garcia, J.R.2
Katsaros, D.3
-
37
-
-
33749319703
-
Type, density, and location of immune cells within human colorectal tumors predict clinical outcome
-
Galon J, Costes A, Sanchez-Cabo F et al. Type, density, and location of immune cells within human colorectal tumors predict clinical outcome. Science (New York, NY.)313(5795), 1960-1964 (2006
-
(2006)
Science (New York, NY.
, vol.313
, Issue.5795
, pp. 1960-1964
-
-
Galon, J.1
Costes, A.2
Sanchez-Cabo, F.3
-
38
-
-
84875535374
-
Trial watch: Prognostic and predictive value of the immune infiltrate in cancer
-
Senovilla L, Vacchelli E, Galon J et al. Trial watch: Prognostic and predictive value of the immune infiltrate in cancer. OncoImmunology 1(8), 1323-1343 (2012
-
(2012)
OncoImmunology
, vol.1
, Issue.8
, pp. 1323-1343
-
-
Senovilla, L.1
Vacchelli, E.2
Galon, J.3
-
39
-
-
77958012775
-
Gene signature in melanoma associated with clinical activity: A potential clue to unlock cancer immunotherapy
-
Gajewski TF, Louahed J, Brichard VG. Gene signature in melanoma associated with clinical activity: A potential clue to unlock cancer immunotherapy. Cancer J. 16(4), 399-403 (2010
-
(2010)
Cancer J.
, vol.16
, Issue.4
, pp. 399-403
-
-
Gajewski, T.F.1
Louahed, J.2
Brichard, V.G.3
-
40
-
-
84863393080
-
Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
-
Gerlinger M, Rowan AJ, Horswell S et al. Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. N. Engl. J. Med. 366(10), 883-892 (2012
-
(2012)
N. Engl. J. Med
, vol.366
, Issue.10
, pp. 883-892
-
-
Gerlinger, M.1
Rowan, A.J.2
Horswell, S.3
-
41
-
-
84887361326
-
Coexistence of divergent escape mechanisms in a patient with braf v600e-mutated cutaneous melanoma treated with vemurafenib
-
Suppl Abstract
-
Romano E, Pradervand S, Paillusson A et al. Coexistence of divergent escape mechanisms in a patient with BRAF V600E-mutated cutaneous melanoma treated with vemurafenib. J. Clin. Oncol. 31(Suppl.), Abstract 9014 (2013
-
(2013)
J. Clin. Oncol
, vol.31
, pp. 9014
-
-
Romano, E.1
Pradervand, S.2
Paillusson, A.3
-
42
-
-
84860389086
-
Tissue-based immune monitoring II: Multiple tumor sites reveal immunologic homogeneity in serous ovarian carcinoma
-
Hagemann AR, Hagemann IS, Cadungog M et al. Tissue-based immune monitoring II: Multiple tumor sites reveal immunologic homogeneity in serous ovarian carcinoma. Cancer Biol. Ther. 12(4), 367-377 (2011
-
(2011)
Cancer Biol. Ther
, vol.12
, Issue.4
, pp. 367-377
-
-
Hagemann, A.R.1
Hagemann, I.S.2
Cadungog, M.3
-
43
-
-
4644324025
-
Cancer immunotherapy: Moving beyond current vaccines
-
Rosenberg SA, Yang JC, Restifo NP. Cancer immunotherapy: Moving beyond current vaccines. Nat. Med. 10(9), 909-915 (2004
-
(2004)
Nat. Med
, vol.10
, Issue.9
, pp. 909-915
-
-
Rosenberg, S.A.1
Yang, J.C.2
Restifo, N.P.3
-
44
-
-
0742304314
-
Evaluation of melanoma vaccines with molecularly defined antigens by ex vivo monitoring of tumor-specific T cells
-
Speiser DE, Pittet MJ, Rimoldi D et al. Evaluation of melanoma vaccines with molecularly defined antigens by ex vivo monitoring of tumor-specific T cells. Semin. Cancer Biol. 13(6), 461-472 (2003
-
(2003)
Semin. Cancer Biol
, vol.13
, Issue.6
, pp. 461-472
-
-
Speiser, D.E.1
Pittet, M.J.2
Rimoldi, D.3
-
45
-
-
84862308565
-
Enhanced cytotoxicity and decreased CD8 dependence of human cancer-specific cytotoxic T lymphocytes after vaccination with low peptide dose
-
Lövgren T, Baumgaertner P, Wieckowski S et al. Enhanced cytotoxicity and decreased CD8 dependence of human cancer-specific cytotoxic T lymphocytes after vaccination with low peptide dose. Cancer Immunol. Immunother. 61(6), 817-826 (2012
-
(2012)
Cancer Immunol. Immunother
, vol.61
, Issue.6
, pp. 817-826
-
-
Lövgren, T.1
Baumgaertner, P.2
Wieckowski, S.3
-
46
-
-
77958492018
-
From vaccines to memory and back
-
Sallusto F, Lanzavecchia A, Araki K, Ahmed R. From vaccines to memory and back. Immunity 33(4), 451-463 (2010
-
(2010)
Immunity
, vol.33
, Issue.4
, pp. 451-463
-
-
Sallusto, F.1
Lanzavecchia, A.2
Araki, K.3
Ahmed, R.4
-
48
-
-
35548938979
-
The expansion and maintenance of antigen-selected CD8(+) T cell clones
-
Fearon DT. The expansion and maintenance of antigen-selected CD8(+) T cell clones. Adv. Immunol. 96, 103-139 (2007
-
(2007)
Adv. Immunol
, vol.96
, pp. 103-139
-
-
Fearon, D.T.1
-
49
-
-
84873395620
-
Superior T memory stem cell persistence supports long-lived T cell memory
-
Lugli E, Dominguez MH, Gattinoni L et al. Superior T memory stem cell persistence supports long-lived T cell memory. J. Clin. Invest. 123(2), 594-599 (2013
-
(2013)
J. Clin. Invest
, vol.123
, Issue.2
, pp. 594-599
-
-
Lugli, E.1
Dominguez, M.H.2
Gattinoni, L.3
-
50
-
-
1542404892
-
Adoptive immunotherapy: Engineering T cell responses as biologic weapons for tumor mass destruction
-
Ho WY, Blattman JN, Dossett ML, Yee C, Greenberg PD. Adoptive immunotherapy: Engineering T cell responses as biologic weapons for tumor mass destruction. Cancer Cell 3(5), 431-437 (2003
-
(2003)
Cancer Cell
, vol.3
, Issue.5
, pp. 431-437
-
-
Ho, W.Y.1
Blattman, J.N.2
Dossett, M.L.3
Yee, C.4
Greenberg, P.D.5
-
51
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126(4), 663-676 (2006
-
(2006)
Cell
, vol.126
, Issue.4
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
52
-
-
84872008549
-
Generation of rejuvenated antigen-specific T cells by reprogramming to pluripotency and redifferentiation
-
Nishimura T, Kaneko S, Kawana-Tachikawa A et al. Generation of Rejuvenated Antigen-Specific T Cells by Reprogramming to Pluripotency and Redifferentiation. Stem Cell 12(1), 114-126 (2013
-
(2013)
Stem Cell
, vol.12
, Issue.1
, pp. 114-126
-
-
Nishimura, T.1
Kaneko, S.2
Kawana-Tachikawa, A.3
-
53
-
-
84872037363
-
Regeneration of Human Tumor Antigen-Specific T Cells from iPSCs Derived from Mature CD8+ T Cells
-
Vizcardo R, Masuda K, Yamada D et al. Regeneration of Human Tumor Antigen-Specific T Cells from iPSCs Derived from Mature CD8+ T Cells. Stem Cell 12(1), 31-36 (2013
-
(2013)
Stem Cell
, vol.12
, Issue.1
, pp. 31-36
-
-
Vizcardo, R.1
Masuda, K.2
Yamada, D.3
-
54
-
-
0026682592
-
Discrepancy between in vitro measurable and in vivo virus neutralizing cytotoxic t cell reactivities low t cell receptor specificity and avidity sufficient for in vitro proliferation or cytotoxicity to peptide-coated target cells but not for in vivo protection
-
Speiser DE, Kyburz D, Stübi U, Hengartner H, Zinkernagel RM. Discrepancy between in vitro measurable and in vivo virus neutralizing cytotoxic T cell reactivities. Low T cell receptor specificity and avidity sufficient for in vitro proliferation or cytotoxicity to peptide-coated target cells but not for in vivo protection. J. Immunol. 149(3), 972-980 (1992
-
(1992)
J. Immunol
, vol.149
, Issue.3
, pp. 972-980
-
-
Speiser, D.E.1
Kyburz, D.2
Stübi, U.3
Hengartner, H.4
Zinkernagel, R.M.5
-
55
-
-
0029965055
-
Selective expansion of highor low-Avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy
-
Alexander-Miller MA, Leggatt GR, Berzofsky JA. Selective expansion of highor low-Avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy. Proc. Natl Acad. Sci. USA 93(9), 4102-4107 (1996
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, Issue.9
, pp. 4102-4107
-
-
Alexander-Miller, M.A.1
Leggatt, G.R.2
Berzofsky, J.A.3
-
56
-
-
84879619273
-
Functional differences between low-And high-Affinity CD8+ T cells in the tumor environment
-
Bos R, Marquardt KL, Cheung J, Sherman LA. Functional differences between low-And high-Affinity CD8+ T cells in the tumor environment. OncoImmunology 1(8), 1239-1247 (2012
-
(2012)
OncoImmunology
, vol.1
, Issue.8
, pp. 1239-1247
-
-
Bos, R.1
Marquardt, K.L.2
Cheung, J.3
Sherman, L.A.4
-
57
-
-
62249131518
-
Complete but curtailed T-cell response to very low-Affinity antigen
-
Zehn D, Lee SY, Bevan MJ. Complete but curtailed T-cell response to very low-Affinity antigen. Nature 457(7235), 211-214 (2009
-
(2009)
Nature
, vol.457
, Issue.7235
, pp. 211-214
-
-
Zehn, D.1
Lee, S.Y.2
Bevan, M.J.3
-
58
-
-
84877666366
-
Hit parade for adoptive cell transfer therapy: The best T cells for superior clinical responses
-
Speiser DE. Hit parade for adoptive cell transfer therapy: The best T cells for superior clinical responses. Cancer Discov. 3(4), 379-381 (2013
-
(2013)
Cancer Discov
, vol.3
, Issue.4
, pp. 379-381
-
-
Speiser, D.E.1
-
59
-
-
84863230570
-
Local delivery of interleukin-12 using T cells targeting VEGF receptor-2 eradicates multiple vascularized tumors in mice
-
Chinnasamy D, Yu Z, Kerkar SP et al. Local delivery of interleukin-12 using T cells targeting VEGF receptor-2 eradicates multiple vascularized tumors in mice. Clin. Cancer Res. 18(6), 1672-1683 (2012
-
(2012)
Clin. Cancer Res
, vol.18
, Issue.6
, pp. 1672-1683
-
-
Chinnasamy, D.1
Yu, Z.2
Kerkar, S.P.3
-
60
-
-
10244279184
-
Mechanisms and functional significance of tumour-induced dendritic-cell defects
-
Gabrilovich D. Mechanisms and functional significance of tumour-induced dendritic-cell defects. Nat. Rev. Immunol. 4(12), 941-952 (2004
-
(2004)
Nat. Rev. Immunol
, vol.4
, Issue.12
, pp. 941-952
-
-
Gabrilovich, D.1
-
61
-
-
84858780815
-
Cancer immunotherapy via dendritic cells
-
Palucka K, Banchereau J. Cancer immunotherapy via dendritic cells. Nat. Rev. Cancer 12(4), 265-277 (2012
-
(2012)
Nat. Rev. Cancer
, vol.12
, Issue.4
, pp. 265-277
-
-
Palucka, K.1
Banchereau, J.2
-
62
-
-
74549174260
-
Dendritic cell-based cancer gene therapy
-
Smits ELJM, Anguille S, Cools N, Berneman ZN, Van Tendeloo VFI. Dendritic cell-based cancer gene therapy. Hum. Gene. Ther. 20(10), 1106-1118 (2009
-
(2009)
Hum. Gene. Ther
, vol.20
, Issue.10
, pp. 1106-1118
-
-
Smits, E.L.J.M.1
Anguille, S.2
Cools, N.3
Berneman, Z.N.4
Van Tendeloo, V.F.I.5
-
63
-
-
68549135290
-
Integrated data from 2 randomized, double-blind, placebo-controlled, phase 3 trials of active cellular immunotherapy with sipuleucel-T in advanced prostate cancer
-
Higano CS, Schellhammer PF, Small EJ et al. Integrated data from 2 randomized, double-blind, placebo-controlled, phase 3 trials of active cellular immunotherapy with sipuleucel-T in advanced prostate cancer. Cancer 115(16), 3670-3679 (2009
-
(2009)
Cancer
, vol.115
, Issue.16
, pp. 3670-3679
-
-
Higano, C.S.1
Schellhammer, P.F.2
Small, E.J.3
-
64
-
-
77149172848
-
Induction of protective immunity against MHC class I-deficient HPV16-Associated tumours with peptide and dendritic cell-based vaccines
-
Reinis M, Stepanek I, Simova J et al. Induction of protective immunity against MHC class I-deficient, HPV16-Associated tumours with peptide and dendritic cell-based vaccines. Int. J. Oncol. 36(3), 545-551 (2010
-
(2010)
Int. J. Oncol
, vol.36
, Issue.3
, pp. 545-551
-
-
Reinis, M.1
Stepanek, I.2
Simova, J.3
-
65
-
-
77953434447
-
Dendritic cell-based vaccines for the therapy of experimental tumors
-
Pajtasz-Piasecka E, Indrova M. Dendritic cell-based vaccines for the therapy of experimental tumors. Immunotherapy 2(2), 257-268 (2010
-
(2010)
Immunotherapy
, vol.2
, Issue.2
, pp. 257-268
-
-
Pajtasz-Piasecka, E.1
Indrova, M.2
-
66
-
-
12144286596
-
In vivo targeting of antigens to maturing dendritic cells via the dec-205 receptor improves t cell vaccination
-
Bonifaz LC. In Vivo Targeting of Antigens to Maturing Dendritic Cells via the DEC-205 Receptor Improves T Cell Vaccination. J. Exp. Med. 199(6), 815-824 (2004
-
(2004)
J. Exp. Med
, vol.199
, Issue.6
, pp. 815-824
-
-
Bonifaz, L.C.1
-
67
-
-
14644390867
-
Rapid and strong human cd8+ t cell responses to vaccination with peptide ifa, and cpg oligodeoxynucleotide 7909
-
Speiser DE, Liénard D, Rufer N et al. Rapid and strong human CD8+ T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909. J. Clin. Invest. 115(3), 739-746 (2005
-
(2005)
J. Clin. Invest
, vol.115
, Issue.3
, pp. 739-746
-
-
Speiser, D.E.1
Liénard, D.2
Rufer, N.3
-
68
-
-
84870359509
-
Phase I trial of overlapping long peptides from a tumor self-Antigen and Poly-ICLC shows rapid induction of integrated immune response in ovarian cancer patients
-
Sabbatini PJ, Tsuji T, Ferran L et al. Phase I trial of overlapping long peptides from a tumor self-Antigen and Poly-ICLC shows rapid induction of integrated immune response in ovarian cancer patients. Clin. Cancer Res. 18(23), 6497-6508 (2012
-
(2012)
Clin. Cancer Res
, vol.18
, Issue.23
, pp. 6497-6508
-
-
Sabbatini, P.J.1
Tsuji, T.2
Ferran, L.3
-
69
-
-
0025764841
-
The gene coding for a major tumor rejection antigen of tumor P815 is identical to the normal gene of syngeneic DBA/2 mice
-
Van den Eynde B, Lethe B, Van Pel A, De Plaen E, Boon T. The gene coding for a major tumor rejection antigen of tumor P815 is identical to the normal gene of syngeneic DBA/2 mice. J. Exp. Med. 173, 1373-1384 (1991
-
(1991)
J. Exp. Med
, vol.173
, pp. 1373-1384
-
-
Van Den Eynde, B.1
Lethe, B.2
Van Pel, A.3
De Plaen, E.4
Boon, T.5
-
70
-
-
0026322151
-
A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma
-
der Bruggen van P, Traversari C, Chomez P et al. A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma. Science (New York, NY.) 254(5038), 1643-1647 (1991
-
(1991)
Science (New York, NY.
, vol.254
, Issue.5038
, pp. 1643-1647
-
-
Der Bruggen Van, P.1
Traversari, C.2
Chomez, P.3
-
71
-
-
0032520084
-
Enhanced generation of specific tumor-reactive CTL in vitro by selected Melan-A/MART-1 immunodominant peptide analogues
-
Valmori D, Fonteneau JF, Lizana CM et al. Enhanced generation of specific tumor-reactive CTL in vitro by selected Melan-A/MART-1 immunodominant peptide analogues. J. Immunol. 160(4), 1750-1758 (1998
-
(1998)
J. Immunol
, vol.160
, Issue.4
, pp. 1750-1758
-
-
Valmori, D.1
Fonteneau, J.F.2
Lizana, C.M.3
-
72
-
-
0030587077
-
Improved induction of melanoma-reactive CTL with peptides from the melanoma antigen gp100 modified at HLA-Ao0201-binding residues
-
Parkhurst MR, Salgaller ML, Southwood S et al. Improved induction of melanoma-reactive CTL with peptides from the melanoma antigen gp100 modified at HLA-Ao0201-binding residues. J. Immunol. 157(6), 2539-2548 (1996
-
(1996)
J. Immunol
, vol.157
, Issue.6
, pp. 2539-2548
-
-
Parkhurst, M.R.1
Salgaller, M.L.2
Southwood, S.3
-
73
-
-
77956914881
-
Modification of MHC anchor residues generates heteroclitic peptides that alter TCR binding and T Cell recognition
-
Cole DK, Edwards ESJ, Wynn KK et al. Modification of MHC anchor residues generates heteroclitic peptides that alter TCR binding and T Cell recognition. J. Immunol. 185(4), 2600-2610 (2010
-
(2010)
J. Immunol
, vol.185
, Issue.4
, pp. 2600-2610
-
-
Cole, D.K.1
Edwards, E.S.J.2
Wynn, K.K.3
-
74
-
-
84868229860
-
T-Cell Receptor optimized peptide skewing of the T-cell repertoire can enhance antigen targeting
-
Ekeruche-Makinde J, Clement M, Cole DK et al. T-Cell Receptor optimized peptide skewing of the T-cell repertoire can enhance antigen targeting. J. Biol. Chem. 287(44), 37269-37181 (2012
-
(2012)
J. Biol. Chem
, vol.287
, Issue.44
, pp. 37269-37181
-
-
Ekeruche-Makinde, J.1
Clement, M.2
Cole, D.K.3
-
75
-
-
41649119810
-
Unmodified self antigen triggers human CD8 T cells with stronger tumor reactivity than altered antigen
-
Speiser DE, Baumgaertner P, Voelter V et al. Unmodified self antigen triggers human CD8 T cells with stronger tumor reactivity than altered antigen. Proc. Natl Acad. Sci. USA 105(10), 3849-3854 (2008
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, Issue.10
, pp. 3849-3854
-
-
Speiser, D.E.1
Baumgaertner, P.2
Voelter, V.3
-
76
-
-
84864196837
-
Simultaneous coexpression of memory-related and effector-related genes by individual human CD8 T Cells depends on antigen specificity and differentiation
-
Gupta B, Iancu EM, Gannon PO et al. Simultaneous coexpression of memory-related and effector-related genes by individual human CD8 T Cells depends on antigen specificity and differentiation. J. Immunother. 35(6), 488-501 (2012
-
(2012)
J. Immunother
, vol.35
, Issue.6
, pp. 488-501
-
-
Gupta, B.1
Iancu, E.M.2
Gannon, P.O.3
-
77
-
-
9044248855
-
Analysis of antigenic heterogeneity within individual 3-methylcholanthrene-induced mouse sarcomas
-
Prehn RT. Analysis of antigenic heterogeneity within individual 3-methylcholanthrene-induced mouse sarcomas. J. Natl Cancer Inst. 45(5), 1039-1045 (1970
-
(1970)
J. Natl Cancer Inst
, vol.45
, Issue.5
, pp. 1039-1045
-
-
Prehn, R.T.1
-
78
-
-
84862891254
-
Highly potent mRNA based cancer vaccines represent an attractive platform for combination therapies supporting an improved therapeutic effect
-
Fotin-Mleczek M, Zanzinger K, Heidenreich R et al. Highly potent mRNA based cancer vaccines represent an attractive platform for combination therapies supporting an improved therapeutic effect. J. Gene. Med. 14(6), 428-439 (2012
-
(2012)
J. Gene. Med
, vol.14
, Issue.6
, pp. 428-439
-
-
Fotin-Mleczek, M.1
Zanzinger, K.2
Heidenreich, R.3
-
79
-
-
84857725402
-
Exploiting the mutanome for tumor vaccination
-
Castle JC, Kreiter S, Diekmann J et al. Exploiting the mutanome for tumor vaccination. Cancer Res. 72(5), 1081-1091 (2012
-
(2012)
Cancer Res
, vol.72
, Issue.5
, pp. 1081-1091
-
-
Castle, J.C.1
Kreiter, S.2
Diekmann, J.3
-
80
-
-
31344453943
-
Immune suppression in cancer: Effects on immune cells, mechanisms and future therapeutic intervention
-
Whiteside TL. Immune suppression in cancer: Effects on immune cells, mechanisms and future therapeutic intervention. Semin. Cancer Biol. 16(1), 3-15 (2006
-
(2006)
Semin. Cancer Biol
, vol.16
, Issue.1
, pp. 3-15
-
-
Whiteside, T.L.1
-
81
-
-
0036547417
-
Death and antideath: Tumour resistance to apoptosis
-
Igney FH, Krammer PH. Death and antideath: Tumour resistance to apoptosis. Nat. Rev. Cancer 2(4), 277-288 (2002
-
(2002)
Nat. Rev. Cancer
, vol.2
, Issue.4
, pp. 277-288
-
-
Igney, F.H.1
Krammer, P.H.2
-
82
-
-
84855817522
-
Immunology in the clinic review series; focus on cancer: Tumour-Associated macrophages: Undisputed stars of the inflammatory tumour microenvironment
-
Allavena P, Mantovani A. Immunology in the clinic review series; focus on cancer: Tumour-Associated macrophages: Undisputed stars of the inflammatory tumour microenvironment. Clin. Exp. Immunol. 167(2), 195-205 (2012
-
(2012)
Clin. Exp. Immunol
, vol.167
, Issue.2
, pp. 195-205
-
-
Allavena, P.1
Mantovani, A.2
-
83
-
-
65249138393
-
Myeloid-derived suppressor cells: Linking inflammation and cancer
-
Ostrand-Rosenberg S, Sinha P. Myeloid-derived suppressor cells: Linking inflammation and cancer. J. Immunol. 182(8), 4499-4506 (2009
-
(2009)
J. Immunol
, vol.182
, Issue.8
, pp. 4499-4506
-
-
Ostrand-Rosenberg, S.1
Sinha, P.2
-
85
-
-
84874280021
-
Positive and negative regulation of T cell responses by fibroblastic reticular cells within paracortical regions of lymph nodes
-
Siegert S, Luther SA. Positive and negative regulation of T cell responses by fibroblastic reticular cells within paracortical regions of lymph nodes. Front. Immunol. 3, 285 (2012
-
(2012)
Front. Immunol
, vol.3
, pp. 285
-
-
Siegert, S.1
Luther, S.A.2
-
86
-
-
60949101225
-
Cancer-Associated fibroblasts and tumor growth-bystanders turning into key players
-
Ostman A, Augsten M. Cancer-Associated fibroblasts and tumor growth-bystanders turning into key players. Curr. Opin. Genet. Dev. 19(1), 67-73 (2009
-
(2009)
Curr. Opin. Genet. Dev
, vol.19
, Issue.1
, pp. 67-73
-
-
Ostman, A.1
Augsten, M.2
-
87
-
-
77951233373
-
Cancer associated fibroblasts (CAFs) in tumor microenvironment
-
Xing F, Saidou J, Watabe K. Cancer associated fibroblasts (CAFs) in tumor microenvironment. Front. Biosci. 15, 166-179 (2010
-
(2010)
Front. Biosci
, vol.15
, pp. 166-179
-
-
Xing, F.1
Saidou, J.2
Watabe, K.3
-
88
-
-
77954721060
-
Regulatory T cells in tumor immunity
-
Nishikawa H, Sakaguchi S. Regulatory T cells in tumor immunity. Int. J. Cancer 127(4), 759-767 (2010
-
(2010)
Int. J. Cancer
, vol.127
, Issue.4
, pp. 759-767
-
-
Nishikawa, H.1
Sakaguchi, S.2
-
89
-
-
36849010167
-
Adaptive immunity maintains occult cancer in an equilibrium state
-
Koebel CM, Vermi W, Swann JB et al. Adaptive immunity maintains occult cancer in an equilibrium state. Nature 450(7171), 903-907 (2007
-
(2007)
Nature
, vol.450
, Issue.7171
, pp. 903-907
-
-
Koebel, C.M.1
Vermi, W.2
Swann, J.B.3
-
90
-
-
33847401888
-
Contribution of the PD-L1/PD-1 pathway to T-cell exhaustion: An update on implications for chronic infections and tumor evasion
-
Blank C, Mackensen A. Contribution of the PD-L1/PD-1 pathway to T-cell exhaustion: An update on implications for chronic infections and tumor evasion. Cancer Immunol. Immunother. 56(5), 739-745 (2007
-
(2007)
Cancer Immunol. Immunother
, vol.56
, Issue.5
, pp. 739-745
-
-
Blank, C.1
Mackensen, A.2
-
91
-
-
84875463042
-
Molecular mechanisms of T cell co-stimulation and co-inhibition
-
Chen L, Flies DB. Molecular mechanisms of T cell co-stimulation and co-inhibition. Nat. Rev. Immunol. 13(4), 227-242 (2013
-
(2013)
Nat. Rev. Immunol
, vol.13
, Issue.4
, pp. 227-242
-
-
Chen, L.1
Flies, D.B.2
-
92
-
-
79954533158
-
Shifting the equilibrium in cancer immunoediting: From tumor tolerance to eradication
-
Quezada SA, Peggs KS, Simpson TR, Allison JP. Shifting the equilibrium in cancer immunoediting: From tumor tolerance to eradication. Immunol. Rev. 241(1), 104-118 (2011
-
(2011)
Immunol. Rev
, vol.241
, Issue.1
, pp. 104-118
-
-
Quezada, S.A.1
Peggs, K.S.2
Simpson, T.R.3
Allison, J.P.4
-
93
-
-
5444225991
-
Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis
-
Yang L, DeBusk LM, Fukuda K et al. Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis. Cancer Cell 6(4), 409-421 (2004
-
(2004)
Cancer Cell
, vol.6
, Issue.4
, pp. 409-421
-
-
Yang, L.1
DeBusk, L.M.2
Fukuda, K.3
-
94
-
-
37349100945
-
Abrogation of tgfb signaling in mammary carcinomas recruits gr-1+cd11b+ myeloid cells that promote metastasis
-
Yang L, Huang J, Ren X et al. Abrogation of TGFb Signaling in Mammary Carcinomas Recruits Gr-1+CD11b+ Myeloid Cells that Promote Metastasis. Cancer Cell 13(1), 23-35 (2008
-
(2008)
Cancer Cell
, vol.13
, Issue.1
, pp. 23-35
-
-
Yang, L.1
Huang, J.2
Ren, X.3
-
95
-
-
0036566184
-
Adapting a transforming growth factor beta-related tumor protection strategy to enhance antitumor immunity
-
Bollard CM, Rossig C, Calonge MJ et al. Adapting a transforming growth factor beta-related tumor protection strategy to enhance antitumor immunity. Blood 99(9), 3179-3187 (2002
-
(2002)
Blood
, vol.99
, Issue.9
, pp. 3179-3187
-
-
Bollard, C.M.1
Rossig, C.2
Calonge, M.J.3
-
96
-
-
79957831345
-
Gp100 peptide vaccine and interleukin-2 in patients with advanced melanoma
-
Schwartzentruber DJ, Lawson DH, Richards JM et al. gp100 peptide vaccine and interleukin-2 in patients with advanced melanoma. N. Engl. J. Med. 364(22), 2119-2127 (2011
-
(2011)
N. Engl. J. Med
, vol.364
, Issue.22
, pp. 2119-2127
-
-
Schwartzentruber, D.J.1
Lawson, D.H.2
Richards, J.M.3
-
97
-
-
77955066199
-
Sipuleucel-T immunotherapy for castration-resistant prostate cancer
-
Kantoff PW, Higano CS, Shore ND et al. Sipuleucel-T immunotherapy for castration-resistant prostate cancer. N. Engl. J. Med. 363(5), 411-422 (2010
-
(2010)
N. Engl. J. Med
, vol.363
, Issue.5
, pp. 411-422
-
-
Kantoff, P.W.1
Higano, C.S.2
Shore, N.D.3
-
98
-
-
84859160195
-
Vaccination-induced functional competence of circulating human tumor-specific CD8 T-cells
-
Baumgaertner P, Jandus C, Rivals J-P et al. Vaccination-induced functional competence of circulating human tumor-specific CD8 T-cells. Int. J. Cancer 130, 2607-2617 (2012
-
(2012)
Int. J. Cancer
, vol.130
, pp. 2607-2617
-
-
Baumgaertner, P.1
Jandus, C.2
Rivals, J.-P.3
-
99
-
-
0018628382
-
Limiting dilution analysis of alloantigen-reactive t lymphocytes ii effect of cortisone and cyclophosphamide on cytolytic t lymphocyte precursor frequencies in the thymus
-
Taswell C, MacDonald HR, Cerottini JC. Limiting dilution analysis of alloantigen-reactive T lymphocytes. II. Effect of cortisone and cyclophosphamide on cytolytic T lymphocyte precursor frequencies in the thymus. Thymus 1, 119-131 (1979
-
(1979)
Thymus
, vol.1
, pp. 119-131
-
-
Taswell, C.1
MacDonald, H.R.2
Cerottini, J.C.3
-
100
-
-
0029743737
-
Phenotypic analysis of antigen-specific T lymphocytes
-
Altman JD, Moss PA, Goulder PJ et al. Phenotypic analysis of antigen-specific T lymphocytes. Science (New York, NY.) 274, 94-96 (1996
-
(1996)
Science (New York, NY.
, vol.274
, pp. 94-96
-
-
Altman, J.D.1
Moss, P.A.2
Goulder, P.J.3
-
101
-
-
77954472387
-
Evidence for a TCR affinity threshold delimiting maximal CD8 T cell function
-
Schmid DA, Irving MB, Posevitz V et al. Evidence for a TCR affinity threshold delimiting maximal CD8 T cell function. J. Immunol. 184(9), 4936-4946 (2010
-
(2010)
J. Immunol
, vol.184
, Issue.9
, pp. 4936-4946
-
-
Schmid, D.A.1
Irving, M.B.2
Posevitz, V.3
-
102
-
-
84874253445
-
Virus-specific CD4+ memory-phenotype T Cells are abundant in unexposed adults
-
Su LF, Kidd BA, Han A, Kotzin JJ, Davis MM. Virus-specific CD4+ memory-phenotype T Cells are abundant in unexposed adults. Immunity 38(2), 373-383 (2013
-
(2013)
Immunity
, vol.38
, Issue.2
, pp. 373-383
-
-
Su, L.F.1
Kidd, B.A.2
Han, A.3
Kotzin, J.J.4
Davis, M.M.5
-
103
-
-
79955750055
-
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum
-
Bendall SC, Simonds EF, Qiu P et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science (New York, NY) 332(6030), 687-696 (2011
-
(2011)
Science (New York, NY
, vol.332
, Issue.6030
, pp. 687-696
-
-
Bendall, S.C.1
Simonds, E.F.2
Qiu, P.3
-
104
-
-
84856278095
-
Cytometry by time-of-flight shows combinatorial cytokine expression and virus-specific cell niches within a continuum of cd8+ t cell phenotypes
-
Newell EW, Sigal N, Bendall SC, Nolan GP, Davis MM. Cytometry by time-of-flight shows combinatorial cytokine expression and virus-specific cell niches within a continuum of CD8+ T Cell phenotypes. Immunity 36(1), 142-152 (2012
-
(2012)
Immunity
, vol.36
, Issue.1
, pp. 142-152
-
-
Newell, E.W.1
Sigal, N.2
Bendall, S.C.3
Nolan, G.P.4
Davis, M.M.5
-
105
-
-
84865592340
-
Cytometry: Today s technology and tomorrow s horizons
-
Chattopadhyay PK, Roederer M. Cytometry: Todays technology and tomorrows horizons. Methods 57(3), 251-258 (2012
-
(2012)
Methods
, vol.57
, Issue.3
, pp. 251-258
-
-
Chattopadhyay, P.K.1
Roederer, M.2
-
106
-
-
35349014587
-
Molecular signature of CD8+ T cell exhaustion during chronic viral infection
-
Wherry EJ, Ha S-J, Kaech SM et al. Molecular signature of CD8+ T cell exhaustion during chronic viral infection. Immunity 27(4), 670-684 (2007
-
(2007)
Immunity
, vol.27
, Issue.4
, pp. 670-684
-
-
Wherry, E.J.1
Ha, S.-J.2
Kaech, S.M.3
-
107
-
-
79957925314
-
Exhaustion of tumor-specific CD8+ T cells in metastases from melanoma patients
-
Baitsch L, Baumgaertner P, Devêvre E et al. Exhaustion of tumor-specific CD8+ T cells in metastases from melanoma patients. J. Clin. Invest. 121(6), 2350-2360 (2011
-
(2011)
J. Clin. Invest
, vol.121
, Issue.6
, pp. 2350-2360
-
-
Baitsch, L.1
Baumgaertner, P.2
Devêvre, E.3
-
108
-
-
79956077563
-
T cell exhaustion
-
Wherry EJ. T cell exhaustion. Nat. Immunol. 131(6), 492-499 (2011
-
(2011)
Nat. Immunol
, vol.131
, Issue.6
, pp. 492-499
-
-
Wherry, E.J.1
-
109
-
-
0344299189
-
Cutting edge: Lymphoproliferative disease in the absence of CTLA-4 is not T cell autonomous
-
Bachmann MF, Köhler G, Ecabert B, Mak TW, Kopf M. Cutting edge: Lymphoproliferative disease in the absence of CTLA-4 is not T cell autonomous. J. Immunol. 163(3), 1128-1131 (1999
-
(1999)
J. Immunol
, vol.163
, Issue.3
, pp. 1128-1131
-
-
Bachmann, M.F.1
Köhler, G.2
Ecabert, B.3
Mak, T.W.4
Kopf, M.5
-
110
-
-
80051944092
-
Cell-Autonomous and-non-Autonomous roles of CTLA-4 in immune regulation
-
Wing K, Yamaguchi T, Sakaguchi S. Cell-Autonomous and-non-Autonomous roles of CTLA-4 in immune regulation. Drug Discov. Today. 32(9), 428-433 (2011
-
(2011)
Drug Discov. Today
, vol.32
, Issue.9
, pp. 428-433
-
-
Wing, K.1
Yamaguchi, T.2
Sakaguchi, S.3
-
111
-
-
84864123005
-
Cutting edge: Cell-extrinsic immune regulation by CTLA-4 expressed on conventional T cells
-
Wang CJ, Kenefeck R, Wardzinski L et al. Cutting edge: Cell-extrinsic immune regulation by CTLA-4 expressed on conventional T cells. J. Immunol. 189(3), 1118-1122 (2012
-
(2012)
J. Immunol
, vol.189
, Issue.3
, pp. 1118-1122
-
-
Wang, C.J.1
Kenefeck, R.2
Wardzinski, L.3
-
112
-
-
84864128521
-
Cutting edge: CTLA-4 on effector T cells inhibits in trans
-
Corse E, Allison JP. Cutting edge: CTLA-4 on effector T cells inhibits in trans. J. Immunol. 189(3), 1123-1127 (2012
-
(2012)
J. Immunol
, vol.189
, Issue.3
, pp. 1123-1127
-
-
Corse, E.1
Allison, J.P.2
-
113
-
-
82255192901
-
The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responses
-
Walker LSK, Sansom DM. The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responses. Nat. Rev. Immunol. 11(12), 852-863 (2011
-
(2011)
Nat. Rev. Immunol
, vol.11
, Issue.12
, pp. 852-863
-
-
Walker, L.S.K.1
Sansom, D.M.2
-
114
-
-
38849163624
-
Sensitive gene expression profiling of human T cell subsets reveals parallel post-Thymic differentiation for CD4+ and CD8+ lineages
-
Appay V, Bosio A, Lokan S et al. Sensitive gene expression profiling of human T cell subsets reveals parallel post-Thymic differentiation for CD4+ and CD8+ lineages. J. Immunol. 179(11), 7406-7414 (2007
-
(2007)
J. Immunol
, vol.179
, Issue.11
, pp. 7406-7414
-
-
Appay, V.1
Bosio, A.2
Lokan, S.3
-
115
-
-
80053082582
-
Single cell analysis reveals similar functional competence of dominant and nondominant CD8 T-cell clonotypes
-
Speiser DE, Wieckowski S, Gupta B et al. Single cell analysis reveals similar functional competence of dominant and nondominant CD8 T-cell clonotypes. Proc. Natl Acad. Sci. USA 108(37), 15318-15323 (2011
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, Issue.37
, pp. 15318-15323
-
-
Speiser, D.E.1
Wieckowski, S.2
Gupta, B.3
-
116
-
-
79958122357
-
A clinical microchip for evaluation of single immune cells reveals high functional heterogeneity in phenotypically similar T cells
-
Ma C, Fan R, Ahmad H et al. A clinical microchip for evaluation of single immune cells reveals high functional heterogeneity in phenotypically similar T cells. Nat. Med. 17(6), 738-743 (2011
-
(2011)
Nat. Med
, vol.17
, Issue.6
, pp. 738-743
-
-
Ma, C.1
Fan, R.2
Ahmad, H.3
-
117
-
-
5144235393
-
Correlation between tumor regression and T cell responses in melanoma patients vaccinated with a MAGE antigen
-
Lonchay C, der Bruggen van P, Connerotte T et al. Correlation between tumor regression and T cell responses in melanoma patients vaccinated with a MAGE antigen. Proc. Natl Acad. Sci. USA 101 (Suppl. 2), 14631-14638 (2004
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, Issue.SUPPL. 2
, pp. 14631-14638
-
-
Lonchay, C.1
Der Bruggen Van, P.2
Connerotte, T.3
-
118
-
-
13244273592
-
Contrasting frequencies of antitumor and anti-vaccine T cells in metastases of a melanoma patient vaccinated with a MAGE tumor antigen
-
Lurquin C, Lethé B, De Plaen E et al. Contrasting frequencies of antitumor and anti-vaccine T cells in metastases of a melanoma patient vaccinated with a MAGE tumor antigen. J. Exp. Med. 201(2), 249-257 (2005
-
(2005)
J. Exp. Med
, vol.201
, Issue.2
, pp. 249-257
-
-
Lurquin, C.1
Lethé, B.2
De Plaen, E.3
-
119
-
-
80051966191
-
Solving vaccine mysteries: A systems biology perspective
-
Trautmann L, Sekaly R-P. Solving vaccine mysteries: A systems biology perspective. Nat. Immunol. 12(8), 729-731 (2011
-
(2011)
Nat. Immunol
, vol.12
, Issue.8
, pp. 729-731
-
-
Trautmann, L.1
Sekaly, R.-P.2
-
120
-
-
45749118607
-
Promoting coherent minimum reporting guidelines for biological and biomedical investigations: The MIBBI project
-
Taylor CF, Field D, Sansone S-A et al. Promoting coherent minimum reporting guidelines for biological and biomedical investigations: The MIBBI project. Nat. Biotechnol. 26(8), 889-896 (2008
-
(2008)
Nat. Biotechnol
, vol.26
, Issue.8
, pp. 889-896
-
-
Taylor, C.F.1
Field, D.2
Sansone, S.-A.3
-
121
-
-
53049110682
-
MIFlowCyt: The minimum information about a flow cytometry experiment
-
Lee JA, Spidlen J, Boyce K et al. MIFlowCyt: The minimum information about a flow cytometry experiment. Cytometry 73A(10), 926-930 (2008
-
(2008)
Cytometry
, vol.73 A
, Issue.10
, pp. 926-930
-
-
Lee, J.A.1
Spidlen, J.2
Boyce, K.3
-
122
-
-
70349833381
-
MIATA-minimal information about T cell assays
-
Janetzki S, Britten CM, Kalos M et al. MIATA-minimal information about T cell assays. Immunity 31(4), 527-528 (2009
-
(2009)
Immunity
, vol.31
, Issue.4
, pp. 527-528
-
-
Janetzki, S.1
Britten, C.M.2
Kalos, M.3
-
123
-
-
79956000143
-
Recommendations from the iSBTc-SITC/ FDA/NCI workshop on immunotherapy biomarkers
-
Butterfield LH, Palucka AK, Britten CM et al. Recommendations from the iSBTc-SITC/FDA/NCI workshop on immunotherapy biomarkers. Clin. Cancer Res. 17(10), 3064-3076 (2011
-
(2011)
Clin. Cancer Res
, vol.17
, Issue.10
, pp. 3064-3076
-
-
Butterfield, L.H.1
Palucka, A.K.2
Britten, C.M.3
-
124
-
-
23244432214
-
Identification of clinically useful cancer prognostic factors: What are we missing
-
McShane LM, Altman DG, Sauerbrei W Identification of clinically useful cancer prognostic factors: What are we missing? J. Natl Cancer Inst. 97(14), 1023-1025 (2005
-
(2005)
J. Natl Cancer Inst
, vol.97
, Issue.14
, pp. 1023-1025
-
-
McShane, L.M.1
Altman, D.G.2
Sauerbrei, W.3
-
125
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D, Weinberg RA. Hallmarks of cancer: The next generation. Cell 144(5), 646-674 (2011
-
(2011)
Cell
, vol.144
, Issue.5
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
126
-
-
84858766182
-
The blockade of immune checkpoints in cancer immunotherapy
-
Pardoll DM. The blockade of immune checkpoints in cancer immunotherapy. Nat. Rev. Cancer. 12(4), 252-264 (2012
-
(2012)
Nat. Rev. Cancer
, vol.12
, Issue.4
, pp. 252-264
-
-
Pardoll, D.M.1
|