-
1
-
-
0024554410
-
The role of HLA class I antigens in recognition of melanoma cells by tumor-specific cytotoxic T lymphocytes. Evidence for shared tumor antigens
-
Darrow TL, Slingluff CL Jr, Seigler HF. The role of HLA class I antigens in recognition of melanoma cells by tumor-specific cytotoxic T lymphocytes. Evidence for shared tumor antigens. J Immunol. 1989; 142:3329-3335. (Pubitemid 19129962)
-
(1989)
Journal of Immunology
, vol.142
, Issue.9
, pp. 3329-3335
-
-
Darrow, T.L.1
Slingluff Jr., C.L.2
Seigler, H.F.3
-
3
-
-
12944325331
-
A listing of human tumor antigens recognized by T cells: March 2004 update
-
DOI 10.1007/s00262-004-0560-6
-
Novellino L, Castelli C, Parmiani G. A listing of human tumor antigens recognized by T cells: March 2004 update. Cancer Immunol Immunother. 2005;54:187-207. (Pubitemid 40174238)
-
(2005)
Cancer Immunology, Immunotherapy
, vol.54
, Issue.3
, pp. 187-207
-
-
Novellino, L.1
Castelli, C.2
Parmiani, G.3
-
4
-
-
35948972459
-
Immunologic and clinical outcomes of a randomized phase II trial of two multipeptide vaccines for melanoma in the adjuvant setting
-
DOI 10.1158/1078-0432.CCR-07-0486
-
Slingluff CL Jr, Petroni GR, Chianese-Bullock KA, et al. Immunologic and clinical outcomes of a randomized phase II trial of two multipeptide vaccines for melanoma in the adjuvant setting. Clin Cancer Res. 2007; 13:6386-6395. (Pubitemid 350075028)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.21
, pp. 6386-6395
-
-
Slingluff Jr., C.L.1
Petroni, G.R.2
Chianese-Bullock, K.A.3
Smolkin, M.E.4
Hibbitts, S.5
Murphy, C.6
Johansen, N.7
Grosh, W.W.8
Yamshchikov, G.V.9
Neese, P.Y.10
Patterson, J.W.11
Fink, R.12
Rehm, P.K.13
-
5
-
-
33646244160
-
Immunity to Melanoma Antigens: From Self-Tolerance to Immunotherapy
-
DOI 10.1016/S0065-2776(06)90007-8, PII S0065277606900078
-
Slingluff CL Jr, Chianese-Bullock KA, Bullock TN, et al. Immunity to melanoma antigens: from self-tolerance to immunotherapy. Adv Immunol. 2006;90:243-295. (Pubitemid 43786236)
-
(2006)
Advances in Immunology
, vol.90
, pp. 243-295
-
-
Slingluff Jr., C.L.1
Chianese-Bullock, K.A.2
Bullock, T.N.J.3
Grosh, W.W.4
Mullins, D.W.5
Nichols, L.6
Olson, W.7
Petroni, G.8
Smolkin, M.9
Engelhard, V.H.10
-
6
-
-
0742304314
-
Evaluation of melanoma vaccines with molecularly defined antigens by ex vivo monitoring of tumor-specific T cells
-
DOI 10.1016/j.semcancer.2003.09.010
-
Speiser DE, Pittet MJ, Rimoldi D, et al. Evaluation of melanoma vaccines with molecularly defined antigens by ex vivo monitoring of tumorspecific T cells. Semin Cancer Biol. 2003;13:461-472. (Pubitemid 38156138)
-
(2003)
Seminars in Cancer Biology
, vol.13
, Issue.6
, pp. 461-472
-
-
Speiser, D.E.1
Pittet, M.J.2
Rimoldi, D.3
Guillaume, P.4
Luescher, I.F.5
Lienard, D.6
Lejeune, F.7
Cerottini, J.-C.8
Romero, P.9
-
7
-
-
27144500671
-
+ T cells in patients with melanoma
-
Rosenberg SA, Sherry RM, Morton KE, et al. Tumor progression can occur despite the induction of very high levels of self/tumor antigenspecific CD8+ T cells in patients with melanoma. J Immunol. 2005; 175:6169-6176. (Pubitemid 41508105)
-
(2005)
Journal of Immunology
, vol.175
, Issue.9
, pp. 6169-6176
-
-
Rosenberg, S.A.1
Sherry, R.M.2
Morton, K.E.3
Scharfman, W.J.4
Yang, J.C.5
Topalian, S.L.6
Royal, R.E.7
Kammula, U.8
Restifo, N.P.9
Hughes, M.S.10
Schwartzentruber, D.11
Berman, D.M.12
Schwarz, S.L.13
Ngo, L.T.14
Mavroukakis, S.A.15
White, D.E.16
Steinberg, S.M.17
-
8
-
-
72549116845
-
Effect of GM-CSF on circulating CD8+ and CD4+ T cell responses to a multipeptide melanoma vaccine: Outcome of a multicenter randomized trial
-
Slingluff CL Jr, Petroni GR, Olson WC, et al. Effect of GM-CSF on circulating CD8+ and CD4+ T cell responses to a multipeptide melanoma vaccine: outcome of a multicenter randomized trial. Clin Cancer Res. 2009;15:7036-7044.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 7036-7044
-
-
Slingluff Jr., C.L.1
Petroni, G.R.2
Olson, W.C.3
-
9
-
-
14644390867
-
+ T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909
-
DOI 10.1172/JCI200523373
-
Speiser DE, Lienard D, Rufer N, et al. Rapid and strong human CD8+ T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909. J Clin Invest. 2005;115:739-746. (Pubitemid 40322250)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.3
, pp. 739-746
-
-
Speiser, D.E.1
Lienard, D.2
Rufer, N.3
Rubio-Godoy, V.4
Rimoldi, D.5
Lejeune, F.6
Krieg, A.M.7
Cerottini, J.-C.8
Romero, P.9
-
10
-
-
34247159208
-
CMV pp65 and IE-1 T cell epitopes recognized by healthy subjects
-
Slezak SL, Bettinotti M, Selleri S, et al. CMV pp65 and IE-1 T cell epitopes recognized by healthy subjects. J Transl Med. 2007;5:17.
-
(2007)
J Transl Med
, vol.5
, pp. 17
-
-
Slezak, S.L.1
Bettinotti, M.2
Selleri, S.3
-
11
-
-
14044259609
-
Immunologic and clinical outcomes of vaccination with a multiepitope melanoma peptide vaccine plus low-dose interleukin-2 administered either concurrently or on a delayed schedule
-
DOI 10.1200/JCO.2004.10.212
-
Slingluff CL Jr, Petroni GR, Yamshchikov GV, et al. Immunologic and clinical outcomes of vaccination with a multiepitope melanoma peptide vaccine plus low-dose interleukin-2 administered either concurrently or on a delayed schedule. J Clin Oncol. 2004;22:4474-4485. (Pubitemid 41185113)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.22
, pp. 4474-4485
-
-
Slingluff Jr., C.L.1
Petroni, G.R.2
Yamshchikov, G.V.3
Hibbitts, S.4
Grosh, W.W.5
Chianese-Bullock, K.A.6
Bissonette, E.A.7
Barnd, D.L.8
Deacon, D.H.9
Patterson, J.W.10
Parekh, J.11
Neese, P.Y.12
Woodson, E.M.H.13
Wiernasz, C.J.14
Merrill, P.15
-
12
-
-
0035371656
-
Evaluation of peptide vaccine immunogenicity in draining lymph nodes and peripheral blood of melanoma patients
-
DOI 10.1002/1097-0215(20010601)92:5<703::AID-IJC1250>3.0.CO;2-5
-
Yamshchikov GV, Barnd DL, Eastham S, et al. Evaluation of peptide vaccine immunogenicity in draining lymph nodes and blood of melanoma patients. Int J Cancer. 2001;92:703-711. (Pubitemid 32385714)
-
(2001)
International Journal of Cancer
, vol.92
, Issue.5
, pp. 703-711
-
-
Yamshchikov, G.V.1
Barnd, D.L.2
Eastham, S.3
Galavotti, H.4
Patterson, J.W.5
Deacon, D.H.6
Teates, D.7
Neese, P.8
Grosh, W.W.9
Petroni, G.10
Engelhard, V.H.11
Slingluff Jr., C.L.12
-
13
-
-
20044373641
-
MAGE-A1-, MAGE-A10-, and gp100-derived peptides are immunogenic when combined with granulocyte-macrophage colony-stimulating factor and montanide ISA-51 adjuvant and administered as part of a multipeptide vaccine for melanoma
-
Chianese-Bullock KA, Pressley J, Garbee C, et al. MAGE-A1-, MAGEA10-, and gp100-derived peptides are immunogenic when combined with granulocyte- macrophage colony-stimulating factor and Montanide ISA-51 adjuvant and administered as part of a multipeptide vaccine for melanoma. J Immunol. 2005;174:3080-3086. (Pubitemid 40279730)
-
(2005)
Journal of Immunology
, vol.174
, Issue.5
, pp. 3080-3086
-
-
Chianese-Bullock, K.A.1
Pressley, J.2
Garbee, C.3
Hibbitts, S.4
Murphy, C.5
Yamshchikov, G.6
Petroni, G.R.7
Bissonette, E.A.8
Neese, P.Y.9
Grosh, W.W.10
Merrill, P.11
Fink, R.12
Woodson, E.M.H.13
Wiernasz, C.J.14
Patterson, J.W.15
Slingluff Jr., C.L.16
-
14
-
-
54449097809
-
Helper T cell responses and clinical activity of a melanoma vaccine with multiple peptides from MAGE and melanocytic differentiation antigens
-
Slingluff CL Jr, Petroni GR, OlsonW, et al. Helper T cell responses and clinical activity of a melanoma vaccine with multiple peptides from MAGE and melanocytic differentiation antigens. J Clin Oncol. 2008;26: 4973-4980.
-
(2008)
J Clin Oncol
, vol.26
, pp. 4973-4980
-
-
Slingluff Jr., C.L.1
Olsonw, P.G.2
-
15
-
-
4644324025
-
Cancer immunotherapy: Moving beyond current vaccines
-
DOI 10.1038/nm1100
-
Rosenberg SA, Yang JC, Restifo NP. Cancer immunotherapy: moving beyond current vaccines. Nat Med. 2004;10:909-915. (Pubitemid 39273730)
-
(2004)
Nature Medicine
, vol.10
, Issue.9
, pp. 909-915
-
-
Rosenberg, S.A.1
Yang, J.C.2
Restifo, N.P.3
-
16
-
-
5444266058
-
E1696: Final analysis of the clinical and immunological results of a multicenter ECOG phase II trial of multi-epitope peptide vaccination for stage IV melanoma with MART-1 (27-35), gp100 (209-217, 210M), and tyrosinase (368-376, 370D) (MGT) +/j IFNa2b and GM-CSF
-
Kirkwood JM, Lee S, Land S, et al. E1696: final analysis of the clinical and immunological results of a multicenter ECOG phase II trial of multi-epitope peptide vaccination for stage IV melanoma with MART-1 (27-35), gp100 (209-217, 210M), and tyrosinase (368-376, 370D) (MGT) +/j IFNa2b and GM-CSF. J Clin Oncol (Meeting Abstracts). 2004;22:7502
-
(2004)
J Clin Oncol (Meeting Abstracts)
, vol.22
, pp. 7502
-
-
Kirkwood, J.M.1
Lee, S.2
Land, S.3
-
17
-
-
0037058993
-
+ T cell clones for the treatment of patients with metastatic melanoma: In vivo persistence, migration, and antitumor effect of transferred T cells
-
DOI 10.1073/pnas.242600099
-
Yee C, Thompson JA, Byrd D, et al. Adoptive T cell therapy using antigen-specific CD8+ T cell clones for the treatment of patients with metastatic melanoma: in vivo persistence, migration, and antitumor effect of transferred T cells. Proc Natl Acad Sci U S A. 2002;99: 16168-16173. (Pubitemid 35462767)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.25
, pp. 16168-16173
-
-
Yee, C.1
Thompson, J.A.2
Byrd, D.3
Riddell, S.R.4
Roche, P.5
Celis, E.6
Greenberg, P.D.7
-
18
-
-
4344671644
-
Effector Function of Human Tumor-Specific CD8 T Cells in Melanoma Lesions: A State of Local Functional Tolerance
-
DOI 10.1158/0008-5472.CAN-03-3066
-
Zippelius A, Batard P, Rubio-Godoy V, et al. Effector function of human tumor-specific CD8 T cells in melanoma lesions: a state of local functional tolerance. Cancer Res. 2004;64:2865-2873. (Pubitemid 38500627)
-
(2004)
Cancer Research
, vol.64
, Issue.8
, pp. 2865-2873
-
-
Zippelius, A.1
Batard, P.2
Rubio-Godoy, V.3
Bioley, G.4
Lienard, D.5
Lejeune, F.6
Rimoldi, D.7
Guillaume, P.8
Meidenbauer, N.9
Mackensen, A.10
Rufer, N.11
Lubenow, N.12
Speiser, D.13
Cerottini, J.-C.14
Romero, P.15
Pittet, M.J.16
-
19
-
-
33846322927
-
Alum with interleukin-12 augments immunity to a melanoma peptide vaccine: Correlation with time to relapse in patients with resected high-risk disease
-
DOI 10.1158/1078-0432.CCR-06-1450
-
Hamid O, Solomon JC, Scotland R, et al. Alum with interleukin-12 augments immunity to a melanoma peptide vaccine: correlation with time to relapse in patients with resected high-risk disease. Clin Cancer Res. 2007;13:215-222. (Pubitemid 46121871)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.1
, pp. 215-222
-
-
Hamid, O.1
Solomon, J.C.2
Scotland, R.3
Garcia, M.4
Sian, S.5
Ye, W.6
Groshen, S.L.7
Weber, J.S.8
-
20
-
-
79960706708
-
A randomized multicenter trial of the effects of melanoma-associated helper peptides and cyclophosphamide on the immunogenicity of a multipeptide melanoma vaccine
-
Slingluff CL Jr, Petroni GR, Chianese-Bullock KA, et al. A randomized multicenter trial of the effects of melanoma-associated helper peptides and cyclophosphamide on the immunogenicity of a multipeptide melanoma vaccine. J Clin Oncol. 2011;29:2924-2932.
-
(2011)
J Clin Oncol
, vol.29
, pp. 2924-2932
-
-
Slingluff Jr., C.L.1
Petroni, G.R.2
Chianese-Bullock, K.A.3
-
21
-
-
60849091328
-
Multi-peptide vaccines vialed as peptide mixtures can be stable reagents for use in peptide-based immune therapies
-
Chianese-Bullock KA, Lewis ST, Sherman NE, et al. Multi-peptide vaccines vialed as peptide mixtures can be stable reagents for use in peptide-based immune therapies. Vaccine. 2009;27:1764-1770.
-
(2009)
Vaccine
, vol.27
, pp. 1764-1770
-
-
Chianese-Bullock, K.A.1
Lewis, S.T.2
Sherman, N.E.3
-
22
-
-
33644521564
-
Ex vivo detectable human CD8 T-cell responses to cancer-testis antigens
-
Baumgaertner P, Rufer N, Devevre E, et al. Ex vivo detectable human CD8 T-cell responses to cancer-testis antigens. Cancer Res. 2006;66: 1912-1916.
-
(2006)
Cancer Res
, vol.66
, pp. 1912-1916
-
-
Baumgaertner, P.1
Rufer, N.2
Devevre, E.3
-
23
-
-
0028304337
-
Identification of a peptide recognized by five melanoma-specific human cytotoxic T cell lines
-
Cox AL, Skipper J, Chen Y, et al. Identification of a peptide recognized by five melanoma-specific human cytotoxic T cell lines. Science. 1994; 264:716-719. (Pubitemid 24185883)
-
(1994)
Science
, vol.264
, Issue.5159
, pp. 716-719
-
-
Cox, A.L.1
Skipper, J.2
Chen, Y.3
Henderson, R.A.4
Darrow, T.L.5
Shabanowitz, J.6
Engelhard, V.H.7
Hunt, D.F.8
Slingluff Jr., C.L.9
-
24
-
-
0034793424
-
280-288 peptide and tetanus helper peptide in adjuvant: Immunologic and clinical outcomes
-
Slingluff CL Jr, Yamshchikov G, Neese P, et al. Phase I trial of a melanoma vaccine with gp100(280-288) peptide and tetanus helper peptide in adjuvant: immunologic and clinical outcomes. Clin Cancer Res. 2001;7:3012-3024. (Pubitemid 32963818)
-
(2001)
Clinical Cancer Research
, vol.7
, Issue.10
, pp. 3012-3024
-
-
Slingluff Jr., C.L.1
Yamshchikov, G.2
Neese, P.3
Galavotti, H.4
Eastham, S.5
Engelhard, V.H.6
Kittlesen, D.7
Deacon, D.8
Hibbitts, S.9
Grosh, W.W.10
Petroni, G.11
Cohen, R.12
Wiernasz, C.13
Patterson, J.W.14
Conway, B.P.15
Ross, W.G.16
-
25
-
-
0034100812
-
Melanomas with concordant loss of multiple melanocytic differentiation proteins: Immune escape that may be overcome by targeting unique or undefined antigens
-
Slingluff CL Jr, Colella TA, Thompson L, et al. Melanomas with concordant loss of multiple melanocytic differentiation proteins: immune escape that may be overcome by targeting unique or undefined antigens. Cancer Immunol Immunother. 2000;48:661-672. (Pubitemid 30146461)
-
(2000)
Cancer Immunology Immunotherapy
, vol.48
, Issue.12
, pp. 661-672
-
-
Slingluff Jr., C.L.1
Colella, T.A.2
Thompson, L.3
Graham, D.D.4
Skipper, J.C.A.5
Caldwell, J.6
Brinckerhoff, L.7
Kittlesen, D.J.8
Deacon, D.H.9
Oei, C.10
Harthun, N.L.11
Huczko, E.L.12
Hunt, D.F.13
Darrow, T.L.14
Engelhard, V.H.15
-
26
-
-
0346024187
-
+ T Lymphocytes in Patients Undergoing Multiple Course Peptide Vaccination
-
DOI 10.1097/00002371-200401000-00004
-
Powell DJ Jr, Rosenberg SA. Phenotypic and functional maturation of tumor antigen-reactive CD8+ T lymphocytes in patients undergoing multiple course peptide vaccination. J Immunother. 2004;27:36-47. (Pubitemid 38076167)
-
(2004)
Journal of Immunotherapy
, vol.27
, Issue.1
, pp. 36-47
-
-
Powell Jr., D.J.1
Rosenberg, S.A.2
-
27
-
-
7444240263
-
Competition among peptides in melanoma vaccines for binding to MHC molecules
-
Thompson LW, Garbee CF, Hibbitts S, et al. Competition among peptides in melanoma vaccines for binding to MHC molecules. J Immunother. 2004;27:425-431. (Pubitemid 39447350)
-
(2004)
Journal of Immunotherapy
, vol.27
, Issue.6
, pp. 425-431
-
-
Thompson, L.W.1
Garbee, C.F.2
Hibbitts, S.3
Brinckerhoff, L.H.4
Pierce, R.A.5
Chianese-Bullock, K.A.6
Deacon, D.H.7
Engelhard, V.H.8
Slingluff Jr., C.L.9
-
28
-
-
33645775260
-
Limited infiltration of exogenous dendritic cells and naive T cells restricts immune responses in peripheral lymph nodes
-
Mullins DW, Engelhard VH. Limited infiltration of exogenous dendritic cells and naive T cells restricts immune responses in peripheral lymph nodes. J Immunol. 2006;176:4535-4542.
-
(2006)
J Immunol
, vol.176
, pp. 4535-4542
-
-
Mullins, D.W.1
Engelhard, V.H.2
-
29
-
-
33646779561
-
Altered CD8(+) T-cellresponses when immunizing with multiepitope peptide vaccines
-
Rosenberg SA, Sherry RM, Morton KE, et al. Altered CD8(+) T-cellresponses when immunizing with multiepitope peptide vaccines. J Immunother. 2006;29:224-231.
-
(2006)
J Immunother
, vol.29
, pp. 224-231
-
-
Rosenberg, S.A.1
Sherry, R.M.2
Morton, K.E.3
-
30
-
-
0025095664
-
Interleukin-2 production by tumor cells bypasses T helper function in the generation of an antitumor response
-
Fearon ER, Pardoll DM, Itaya T, et al. Interleukin-2 production by tumor cells bypasses T helper function in the generation of an antitumor response. Cell. 1990;60:397-403.
-
(1990)
Cell
, vol.60
, pp. 397-403
-
-
Fearon, E.R.1
Pardoll, D.M.2
Itaya, T.3
-
31
-
-
0026331269
-
Treatment of established renal cancer by tumor cells engineered to secrete interleukin-4
-
Golumbek PT, Lazenby AJ, Levitsky HI, et al. Treatment of established renal cancer by tumor cells engineered to secrete interleukin-4. Science. 1991;254:713-716. (Pubitemid 21917394)
-
(1991)
Science
, vol.254
, Issue.5032
, pp. 713-716
-
-
Golumbek, P.T.1
Lazenby, A.J.2
Levitsky, H.I.3
Jaffee, L.M.4
Karasuyama, H.5
Baker, M.6
Pardoll, D.M.7
-
32
-
-
0027538181
-
Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity
-
Dranoff G, Jaffee E, Lazenby A, et al. Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colonystimulating factor stimulates potent, specific, and long-lasting antitumor immunity. Proc Natl Acad Sci U S A. 1993;90:3539-3543. (Pubitemid 23111402)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.8
, pp. 3539-3543
-
-
Dranoff, G.1
Jaffee, E.2
Lazenby, A.3
Golumbek, P.4
Levitsky, H.5
Brose, K.6
Jackson, V.7
Hamada, H.8
Pardoll, D.9
Mulligan, R.C.10
-
33
-
-
0024466940
-
Eradication of adenovirus E1-induced tumors by E1A-specific cytotoxic T lymphocytes
-
DOI 10.1016/0092-8674(89)90006-8
-
Kast WM, Offringa R, Peters PJ, et al. Eradication of adenovirus E1- induced tumors by E1A-specific cytotoxic T lymphocytes. Cell. 1989; 59:603-614. (Pubitemid 19282867)
-
(1989)
Cell
, vol.59
, Issue.4
, pp. 603-614
-
-
Kast, W.M.1
Offringa, R.2
Peters, P.J.3
Voordouw, A.C.4
Meloen, R.H.5
Van Der Eb, A.J.6
Melief, C.J.M.7
-
34
-
-
0028960970
-
Principles for adoptive T cell therapy of human viral diseases
-
Greenberg PD, Riddell SR. Principles for adoptive T cell therapy of human viral diseases. Annu Rev Immunol. 1995;13:545-586.
-
(1995)
Annu Rev Immunol
, vol.13
, pp. 545-586
-
-
Greenberg, P.D.1
Riddell, S.R.2
-
35
-
-
0032822960
-
Anti-tumour activity against B16-F10 melanoma with a GM-CSF secreting allogeneic tumour cell vaccine
-
DOI 10.1038/sj.gt.3300961
-
Kayaga J, Souberbielle BE, Sheikh N, et al. Anti-tumour activity against B16-F10 melanoma with a GM-CSF secreting allogeneic tumour cell vaccine. Gene Ther. 1999;6:1475-1481 [published erratum appears in Gene Ther. 1999;6:1905]. (Pubitemid 29396736)
-
(1999)
Gene Therapy
, vol.6
, Issue.8
, pp. 1475-1481
-
-
Kayaga, J.1
Souberbielle, B.E.2
Sheikh, N.3
Morrow, W.J.W.4
Scott-Taylor, T.5
Vile, R.6
Dalgleish, A.G.7
-
36
-
-
0025761922
-
CD4+ T cell clones specific for the human p97 melanoma-associated antigen can eradicate pulmonary metastases from a murine tumor expressing the p97 antigen
-
Kahn M, Sugawara H, McGowan P, et al. CD4+ T cell clones specific for the human p97 melanoma-associated antigen can eradicate pulmonary metastases from a murine tumor expressing the p97 antigen. J Immunol. 1991;146:3235-3241.
-
(1991)
J Immunol
, vol.146
, pp. 3235-3241
-
-
Kahn, M.1
Sugawara, H.2
McGowan, P.3
-
37
-
-
45549099784
-
Treatment of metastatic melanoma with autologous CD4+ T cells against NY-ESO-1
-
DOI 10.1056/NEJMoa0800251
-
Hunder NN, Wallen H, Cao J, et al. Treatment of metastatic melanoma with autologous CD4+ T cells against NY-ESO-1. N Engl J Med. 2008;358:2698-2703. (Pubitemid 351860862)
-
(2008)
New England Journal of Medicine
, vol.358
, Issue.25
, pp. 2698-2703
-
-
Hunder, N.N.1
Wallen, H.2
Cao, J.3
Hendricks, D.W.4
Reilly, J.Z.5
Rodmyre, R.6
Jungbluth, A.7
Gnjatic, S.8
Thompson, J.A.9
Yee, C.10
-
38
-
-
0027163491
-
+ T cells in immunity to malaria sporozoites
-
Weiss WR, Sedegah M, Berzofsky JA, et al. The role of CD4+ T cells in immunity to malaria sporozoites. J Immunol. 1993;151:2690-2698. (Pubitemid 23264520)
-
(1993)
Journal of Immunology
, vol.151
, Issue.5
, pp. 2690-2698
-
-
Weiss, W.R.1
Sedegah, M.2
Berzofsky, J.A.3
Hoffman, S.L.4
-
39
-
-
0032433127
-
+ T cells in the antitumor immune response
-
DOI 10.1084/jem.188.12.2357
-
Hung K, Hayashi R, Lafond-Walker A, et al. The central role of CD4+ T cells in the antitumor immune response. J Exp Med. 1998;188: 2357-2368. (Pubitemid 29028508)
-
(1998)
Journal of Experimental Medicine
, vol.188
, Issue.12
, pp. 2357-2368
-
-
Hung, K.1
Hayashi, R.2
Lafond-Walker, A.3
Lowenstein, C.4
Pardoll, D.5
Levitsky, H.6
-
40
-
-
0033168607
-
+ CTL tumor immunosurveillance and regulation of tumor escape by CD4 T cells through an effect on quality of CTL
-
Matsui S, Ahlers JD, Vortmeyer AO, et al. A model for CD8+ CTL tumor immunosurveillance and regulation of tumor escape by CD4 T cells through an effect on quality of CTL. J Immunol. 1999;163: 184-193. (Pubitemid 29295840)
-
(1999)
Journal of Immunology
, vol.163
, Issue.1
, pp. 184-193
-
-
Matsui, S.1
Ahlers, J.D.2
Vortmeyer, A.O.3
Terabe, M.4
Tsukui, T.5
Carbone, D.P.6
Liotta, L.A.7
Berzofsky, J.A.8
-
41
-
-
0031782910
-
+ T cell responses in antitumor immunity
-
DOI 10.1016/S0952-7915(98)80228-8
-
Pardoll DM, Topalian Sl. The role of CD4+ T cell responses in antitumor immunity. Curr Opin Immunol. 1998;10:588-594. (Pubitemid 28479193)
-
(1998)
Current Opinion in Immunology
, vol.10
, Issue.5
, pp. 588-594
-
-
Pardoll, D.M.1
Topalian, S.L.2
-
42
-
-
33845917387
-
Addition of GM-CSF to a peptide/KLH vaccine results in increased frequencies of CXCR3-expressing KLH-specific T cells
-
DOI 10.1007/s00262-006-0198-7
-
Na IK, Keilholz U, Letsch A, et al. Addition of GM-CSF to a peptide/ KLH vaccine results in increased frequencies of CXCR3-expressing KLH-specific T cells. Cancer Immunol Immunother. 2007;56:391-396. (Pubitemid 46035907)
-
(2007)
Cancer Immunology, Immunotherapy
, vol.56
, Issue.3
, pp. 391-396
-
-
Na, I.-K.1
Keilholz, U.2
Letsch, A.3
Bauer, S.4
Asemissen, A.M.5
Nagorsen, D.6
Thiel, E.7
Scheibenbogen, C.8
-
43
-
-
0028981087
-
GM2-KLH conjugate vaccine: Increased immunogenicity in melanoma patients after administration with immunological adjuvant QS-21
-
Helling F, Zhang S, Shang A, et al. GM2-KLH conjugate vaccine: increased immunogenicity in melanoma patients after administration with immunological adjuvant QS-21. Cancer Res. 1995;55:2783-2788.
-
(1995)
Cancer Res
, vol.55
, pp. 2783-2788
-
-
Helling, F.1
Zhang, S.2
Shang, A.3
-
44
-
-
0037457311
-
Effects of granulocyte-macrophage colony-stimulating factor and foreign helper protein as immunologic adjuvants on the t-cell response to vaccination with tyrosinase peptides
-
DOI 10.1002/ijc.10961
-
Scheibenbogen C, Schadendorf D, Bechrakis NE, et al. Effects of granulocyte-macrophage colony-stimulating factor and foreign helper protein as immunologic adjuvants on the T-cell response to vaccination with tyrosinase peptides. Int J Cancer. 2003;104:188-194. (Pubitemid 36249794)
-
(2003)
International Journal of Cancer
, vol.104
, Issue.2
, pp. 188-194
-
-
Scheibenbogen, C.1
Schadendorf, D.2
Bechrakis, N.E.3
Nagorsen, D.4
Hofmann, U.5
Servetopoulou, F.6
Letsch, A.7
Philipp, A.8
Foerster, M.H.9
Schmittel, A.10
Thiel, E.11
Keilholz, U.12
-
45
-
-
0030955428
-
Potent immunogenic short linear peptide constructs composed of B cell epitopes and Pan DR T helper epitopes (PADRE) for antibody responses in vivo
-
DOI 10.1016/S0264-410X(97)00186-2, PII S0264410X97001867
-
Del Guercio MF, Alexander J, Kubo RT, et al. Potent immunogenic short linear peptide constructs composed of B cell epitopes and Pan DR T helper epitopes (PADRE) for antibody responses in vivo. Vaccine. 1997;15:441-448. (Pubitemid 27157695)
-
(1997)
Vaccine
, vol.15
, Issue.4
, pp. 441-448
-
-
Del Guercio, M.-F.1
Alexander, J.2
Kubo, R.T.3
Arrhenius, T.4
Maewal, A.5
Appella, E.6
Hoffman, S.L.7
Jones, T.8
Valmori, D.9
Sakaguchi, K.10
Grey, H.M.11
Sette, A.12
-
46
-
-
0026703523
-
Use of human universally antigenic tetanus toxin T cell epitopes as carriers for human vaccination
-
Valmori D, Pessi A, Bianchi E, et al. Use of human universally antigenic tetanus toxin T cell epitopes as carriers for human vaccination. J Immunol. 1992;149:717-721.
-
(1992)
J Immunol
, vol.149
, pp. 717-721
-
-
Valmori, D.1
Pessi, A.2
Bianchi, E.3
-
48
-
-
0034793424
-
280-288 peptide and tetanus helper peptide in adjuvant: Immunologic and clinical outcomes
-
Slingluff CL Jr, Yamshchikov G, Neese P, et al. Phase I trial of a melanoma vaccine with gp100(280-288) peptide and tetanus helper peptide in adjuvant: immunologic and clinical outcomes. Clin Cancer Res. 2001;7:3012-3024. (Pubitemid 32963818)
-
(2001)
Clinical Cancer Research
, vol.7
, Issue.10
, pp. 3012-3024
-
-
Slingluff Jr., C.L.1
Yamshchikov, G.2
Neese, P.3
Galavotti, H.4
Eastham, S.5
Engelhard, V.H.6
Kittlesen, D.7
Deacon, D.8
Hibbitts, S.9
Grosh, W.W.10
Petroni, G.11
Cohen, R.12
Wiernasz, C.13
Patterson, J.W.14
Conway, B.P.15
Ross, W.G.16
-
49
-
-
0029979997
-
+ T cells recognize nonmutated HLA-DR-restricted tyrosinase epitopes
-
DOI 10.1084/jem.183.5.1965
-
Topalian SL, Gonzales MI, Parkhurst M, et al. Melanoma-specific CD4+ T cells recognize nonmutated HLA-DRYrestricted tyrosinase epitopes. J Exp Med. 1996;183:1965-1971. (Pubitemid 26158888)
-
(1996)
Journal of Experimental Medicine
, vol.183
, Issue.5
, pp. 1965-1971
-
-
Topalian, S.L.1
Gonzales, M.I.2
Parkhurst, M.3
Li, Y.F.4
Southwood, S.5
Sette, A.6
Rosenberg, S.A.7
Robbins, P.F.8
-
50
-
-
0031974381
-
+ T cells from peripheral blood of a melanoma patient recognize peptides derived from nonmutated tyrosinase
-
Kobayashi H, Kokubo T, Sato K, et al. CD4+ T cells from peripheral blood of a melanoma patient recognize peptides derived from nonmutated tyrosinase. Cancer Res. 1998;58:296-301. (Pubitemid 28047070)
-
(1998)
Cancer Research
, vol.58
, Issue.2
, pp. 296-301
-
-
Kobayashi, H.1
Kokubo, T.2
Sato, K.3
Kimura, S.4
Asano, K.5
Takahashi, H.6
Iizuka, H.7
Miyokawa, N.8
Katagiri, M.9
-
51
-
-
0034602674
-
+ T cells
-
DOI 10.1073/pnas.97.1.400
-
Zarour HM, Kirkwood JM, Kierstead LS, et al. Melan-A/MART- 1(51-73) represents an immunogenic HLA-DR4-restricted epitope recognized by melanoma-reactive CD4(+) T cells. Proc Natl Acad Sci U S A. 2000;97:400-405. (Pubitemid 30055843)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.1
, pp. 400-405
-
-
Zarour, H.M.1
Kirkwood, J.M.2
Kierstead, L.S.3
Herr, W.4
Brusic, V.5
Slingluff Jr., C.L.6
Sidney, J.7
Sette, A.8
Storkus, W.J.9
-
52
-
-
0033103192
-
+ cytotoxic T cells in association with histocompatibility leukocyte antigen DR11
-
DOI 10.1084/jem.189.5.871
-
Manici S, Sturniolo T, Imro MA, et al. Melanoma cells present a MAGE-3 epitope to CD4(+) cytotoxic T cells in association with histocompatibility leukocyte antigen DR11. J Exp Med. 1999;189:871-876. (Pubitemid 29189692)
-
(1999)
Journal of Experimental Medicine
, vol.189
, Issue.5
, pp. 871-876
-
-
Manici, S.1
Sturniolo, T.2
Imro, M.A.3
Hammer, J.4
Sinigaglia, F.5
Noppen, C.6
Spagnoli, G.7
Mazzi, B.8
Bellone, M.9
Dellabona, P.10
Protti, M.P.11
-
53
-
-
0033103512
-
Identification of MAGE-3 epitopes presented by HLA-DR molecules to CD4(+) T lymphocytes [see comments]
-
Chaux P, Vantomme V, Stroobant V, et al. Identification of MAGE-3 epitopes presented by HLA-DR molecules to CD4(+) T lymphocytes [see comments]. J Exp Med. 1999;189:767-778.
-
(1999)
J Exp Med
, vol.189
, pp. 767-778
-
-
Chaux, P.1
Vantomme, V.2
Stroobant, V.3
-
54
-
-
0030802482
-
Isolation of novel HLA-DR restricted potential tumor-associated antigens from the melanoma cell line FM3
-
Halder T, Pawelec G, Kirkin AF, et al. Isolation of novel HLA-DR restricted potential tumor-associated antigens from the melanoma cell line FM3. Cancer Res. 1997;57:3238-3244. (Pubitemid 27351741)
-
(1997)
Cancer Research
, vol.57
, Issue.15
, pp. 3238-3244
-
-
Halder, T.1
Pawelec, G.2
Kirkin, A.F.3
Zeuthen, J.4
Meyer, H.E.5
Kun, L.6
Kalbacher, H.7
-
55
-
-
0031690656
-
Tumour-specific MHC-class-II-restricted responses after in vitro sensitization to synthetic peptides corresponding to gp100 and Annexin II eluted from melanoma cells
-
DOI 10.1007/s002620050501
-
Li K, Adibzadeh M, Halder T, et al. Tumour-specific MHC-class-IIY restricted responses after in vitro sensitization to synthetic peptides corresponding to gp100 and Annexin II eluted from melanoma cells. Cancer Immunol Immunother. 1998;47:32-38. (Pubitemid 28430528)
-
(1998)
Cancer Immunology Immunotherapy
, vol.47
, Issue.1
, pp. 32-38
-
-
Li, K.1
Adibzadeh, M.2
Halder, T.3
Kalbacher, H.4
Heinzel, S.5
Muller, C.6
Zeuthen, J.7
Pawelec, G.8
-
56
-
-
7444253937
-
Immunization of HLA-A*0201 and/or HLA-DP 104 patients with metastatic melanoma using epitopes from the NY-ESO-1 antigen
-
Khong HT, Yang JC, Topalian SL, et al. Immunization of HLA-A*0201 and/or HLA-DPbeta104 patients with metastatic melanoma using epitopes from the NY-ESO-1 antigen. J Immunother. 2004;27:472-477. (Pubitemid 39447355)
-
(2004)
Journal of Immunotherapy
, vol.27
, Issue.6
, pp. 472-477
-
-
Khong, H.T.1
Yang, J.C.2
Topalian, S.L.3
Sherry, R.M.4
Mavroukakis, S.A.5
White, D.E.6
Rosenberg, S.A.7
-
57
-
-
10744222813
-
Immunization of patients with metastatic melanoma using both class I- and class II-restricted peptides from melanoma-associated antigens
-
DOI 10.1097/00002371-200307000-00007
-
Phan GQ, Touloukian CE, Yang JC, et al. Immunization of patients with metastatic melanoma using both class IY and class-restricted peptides from melanoma-associated antigens. J Immunother. 2003;26: 349-356. (Pubitemid 36858719)
-
(2003)
Journal of Immunotherapy
, vol.26
, Issue.4
, pp. 349-356
-
-
Phan, G.Q.1
Touloukian, C.E.2
Yang, J.C.3
Restifo, N.P.4
Sherry, R.M.5
Hwu, P.6
Topalian, S.L.7
Schwartzentruber, D.J.8
Seipp, C.A.9
Freezer, L.J.10
Morton, K.E.11
Mavroukakis, S.A.12
White, D.E.13
Rosenberg, S.A.14
-
58
-
-
4143107936
-
Immune responses to a class II helper peptide epitope in patients with stage III/IV resected melanoma
-
DOI 10.1158/1078-0432.CCR-04-0241
-
Wong R, Lau R, Chang J, et al. Immune responses to a class II helper peptide epitope in patients with stage III/IV resected melanoma. Clin Cancer Res. 2004;10:5004-5013. (Pubitemid 39099774)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.15
, pp. 5004-5013
-
-
Wong, R.1
Lau, R.2
Chang, J.3
Kuus-Reichel, T.4
Brichard, V.5
Bruck, C.6
Weber, J.7
-
59
-
-
4644249757
-
+ T cells
-
DOI 10.1084/jem.20041270
-
Lichterfeld M, Kaufmann DE, Yu XG, et al. Loss of HIV-1Yspecific CD8+ T cell proliferation after acute HIV-1 infection and restoration by vaccine-induced HIV-1-specific CD4+ T cells. J Exp Med. 2004;200: 701-712. (Pubitemid 39299457)
-
(2004)
Journal of Experimental Medicine
, vol.200
, Issue.6
, pp. 701-712
-
-
Lichterfeld, M.1
Kaufmann, D.E.2
Yu, X.G.3
Mui, S.K.4
Addo, M.M.5
Johnston, M.N.6
Cohen, D.7
Robbins, G.K.8
Pae, E.9
Alter, G.10
Wurcel, A.11
Stone, D.12
Rosenberg, E.S.13
Walker, B.D.14
Altfeld, M.15
-
60
-
-
10744222813
-
Immunization of patients with metastatic melanoma using both class I- and class II-restricted peptides from melanoma-associated antigens
-
DOI 10.1097/00002371-200307000-00007
-
Phan GQ, Touloukian CE, Yang JC, et al. Immunization of patients with metastatic melanoma using both class IY and class-restricted peptides from melanoma-associated antigens. J Immunother. 2003;26:349-356. (Pubitemid 36858719)
-
(2003)
Journal of Immunotherapy
, vol.26
, Issue.4
, pp. 349-356
-
-
Phan, G.Q.1
Touloukian, C.E.2
Yang, J.C.3
Restifo, N.P.4
Sherry, R.M.5
Hwu, P.6
Topalian, S.L.7
Schwartzentruber, D.J.8
Seipp, C.A.9
Freezer, L.J.10
Morton, K.E.11
Mavroukakis, S.A.12
White, D.E.13
Rosenberg, S.A.14
-
61
-
-
4143107936
-
Immune responses to a class II helper peptide epitope in patients with stage III/IV resected melanoma
-
DOI 10.1158/1078-0432.CCR-04-0241
-
Wong R, Lau R, Chang J, et al. Immune responses to a class II helper peptide epitope in patients with stage III/IV resected melanoma. Clin Cancer Res. 2004;10:5004-5013. (Pubitemid 39099774)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.15
, pp. 5004-5013
-
-
Wong, R.1
Lau, R.2
Chang, J.3
Kuus-Reichel, T.4
Brichard, V.5
Bruck, C.6
Weber, J.7
-
62
-
-
0035113705
-
Immunization with a HER-2/neu helper peptide vaccine generates HER-2/neu CD8 T-cell immunity in cancer patients
-
Knutson KL, Schiffman K, Disis Ml. Immunization with a HER-2/neu helper peptide vaccine generates HER-2/neu CD8 T-cell immunity in cancer patients. J Clin Invest. 2001;107:477-484. (Pubitemid 32167994)
-
(2001)
Journal of Clinical Investigation
, vol.107
, Issue.4
, pp. 477-484
-
-
Knutson, K.L.1
Schiffman, K.2
Disis, M.L.3
-
63
-
-
79960741390
-
First report of a randomized phase II trial of multi-epitope vaccination with melanoma peptides for cytotoxic T cells and helper T cells in patients with metastatic melanoma: An Eastern Cooperative Oncology Group Study (E1602)
-
Abstract 8508
-
Slingluff CL Jr, Lee SJ, Chianese-Bullock KA, et al. First report of a randomized phase II trial of multi-epitope vaccination with melanoma peptides for cytotoxic T cells and helper T cells in patients with metastatic melanoma: An Eastern Cooperative Oncology Group Study (E1602). J Clin Oncol. 2010;28. Abstract 8508.
-
(2010)
J Clin Oncol.
, pp. 28
-
-
Slingluff Jr., C.L.1
Lee, S.J.2
Chianese-Bullock, K.A.3
-
64
-
-
54549089744
-
Phosphorylationdependent interaction between antigenic peptides and MHC class I: A molecular basis for the presentation of transformed self
-
Mohammed F, Cobbold M, Zarling AL, et al. Phosphorylationdependent interaction between antigenic peptides and MHC class I: a molecular basis for the presentation of transformed self. Nat Immunol. 2008;9:1236-1243.
-
(2008)
Nat Immunol
, vol.9
, pp. 1236-1243
-
-
Mohammed, F.1
Cobbold, M.2
Zarling, A.L.3
-
65
-
-
67749145750
-
Identification of tumorassociated MHC class-restricted phosphopeptides as targets for immunotherapy
-
Depontieu FR, Qian J, Zarling AL, et al. Identification of tumorassociated, MHC class-restricted phosphopeptides as targets for immunotherapy. Proc Natl Acad Sci U S A. 2009;106:12073-12078.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 12073-12078
-
-
Depontieu, F.R.1
Qian, J.2
Zarling, A.L.3
-
66
-
-
77954762820
-
Structural basis for the presentation of tumor-associated MHC class-restricted phosphopeptides to CD4+ T cells
-
Li Y, Depontieu FR, Sidney J, et al. Structural basis for the presentation of tumor-associated MHC class-restricted phosphopeptides to CD4+ T cells. J Mol Biol. 2010;399:596-603.
-
(2010)
J Mol Biol
, vol.399
, pp. 596-603
-
-
Li, Y.1
Depontieu, F.R.2
Sidney, J.3
-
67
-
-
77954960118
-
Immunogenicity for CD8+ and CD4+ T cells of two formulations of an incomplete Freunds adjuvant for multipeptide melanoma vaccines
-
Slingluff CL Jr, Petroni GR, Smolkin ME, et al. Immunogenicity for CD8+ and CD4+ T cells of two formulations of an incomplete Freunds adjuvant for multipeptide melanoma vaccines. J Immunother. 2010;33: 630-638.
-
(2010)
J Immunother
, vol.33
, pp. 630-638
-
-
Slingluff Jr., C.L.1
Petroni, G.R.2
Smolkin, M.E.3
-
68
-
-
77954958313
-
Different adjuvanticity of incomplete Freunds adjuvant derived from beef or vegetable components in melanoma patients immunized with a peptide vaccine
-
Rosenberg SA, Yang JC, Kammula US, et al. Different adjuvanticity of incomplete Freunds adjuvant derived from beef or vegetable components in melanoma patients immunized with a peptide vaccine. J Immunother. 2010;33:626-629.
-
(2010)
J Immunother
, vol.33
, pp. 626-629
-
-
Rosenberg, S.A.1
Yang, J.C.2
Kammula, U.S.3
-
69
-
-
77956527209
-
Dynamic changes in cellular infiltrates with repeated cutaneous vaccination: A histologic and immunophenotypic analysis
-
Schaefer JT, Patterson JW, Deacon DH, et al. Dynamic changes in cellular infiltrates with repeated cutaneous vaccination: a histologic and immunophenotypic analysis. J Transl Med. 2010;8:79.
-
(2010)
J Transl Med
, vol.8
, pp. 79
-
-
Schaefer, J.T.1
Patterson, J.W.2
Deacon, D.H.3
-
70
-
-
77954951500
-
Peptide/incomplete Freund adjuvant emulsion depots are a graveyard for tumor antigen-specific CD8+ T cells [abstract]
-
Overwijk W, Hailemichael Y, Dai Z, et al. Peptide/incomplete Freund adjuvant emulsion depots are a graveyard for tumor antigen-specific CD8+ T cells [abstract]. J Immunother. 2009;32:971
-
(2009)
J Immunother
, vol.32
, pp. 971
-
-
Overwijk, W.1
Hailemichael, Y.2
Dai, Z.3
-
71
-
-
76649093262
-
Using 3 TLR ligands as a combination adjuvant induces qualitative changes in T cell responses needed for antiviral protection in mice
-
Zhu Q, Egelston C, Gagnon S, et al. Using 3 TLR ligands as a combination adjuvant induces qualitative changes in T cell responses needed for antiviral protection in mice. J Clin Invest. 2010;120:607-616.
-
(2010)
J Clin Invest
, vol.120
, pp. 607-616
-
-
Zhu, Q.1
Egelston, C.2
Gagnon, S.3
-
72
-
-
65249164025
-
Multiple signaling pathways contribute to synergistic TLR ligand-dependent cytokine gene expression in human monocyte-derived macrophages and dendritic cells
-
Makela SM, Strengell M, Pietila TE, et al. Multiple signaling pathways contribute to synergistic TLR ligand-dependent cytokine gene expression in human monocyte-derived macrophages and dendritic cells. J Leukoc Biol. 2009;85:664-672.
-
(2009)
J Leukoc Biol
, vol.85
, pp. 664-672
-
-
Makela, S.M.1
Strengell, M.2
Pietila, T.E.3
-
73
-
-
0141923686
-
Toll-like receptor ligands modulate dendritic cells to augment cytomegalovirus- and HIV-1-specific T cell responses
-
Lore K, Betts MR, Brenchley JM, et al. Toll-like receptor ligands modulate dendritic cells to augment cytomegalovirus- and HIV-1Yspecific T cell responses. J Immunol. 2003;171:4320-4328. (Pubitemid 37238711)
-
(2003)
Journal of Immunology
, vol.171
, Issue.8
, pp. 4320-4328
-
-
Lore, K.1
Betts, M.R.2
Brenchley, J.M.3
Kuruppu, J.4
Khojasteh, S.5
Perfetto, S.6
Roederer, M.7
Seder, R.A.8
Koup, R.A.9
-
75
-
-
34250854079
-
The vaccine adjuvant monophosphoryl lipid A as a TRIF-biased agonist of TLR4
-
DOI 10.1126/science.1138963
-
Mata-Haro V, Cekic C, Martin M, et al. The vaccine adjuvant monophosphoryl lipid A as a TRIF-biased agonist of TLR4. Science. 2007; 316:1628-1632. (Pubitemid 46982038)
-
(2007)
Science
, vol.316
, Issue.5831
, pp. 1628-1632
-
-
Mata-Haro, V.1
Cekic, C.2
Martin, M.3
Chilton, P.M.4
Casella, C.R.5
Mitchell, T.C.6
-
76
-
-
23944509107
-
+ regulatory T cell function
-
DOI 10.1126/science.1113401
-
Peng G, Guo Z, Kiniwa Y, et al. Toll-like receptor 8Ymediated reversal of CD4+ regulatory T cell function. Science. 2005;309:1380-1384. (Pubitemid 41209366)
-
(2005)
Science
, vol.309
, Issue.5739
, pp. 1380-1384
-
-
Peng, G.1
Guo, Z.2
Kiniwa, Y.3
Voo, K.S.4
Peng, W.5
Fu, T.6
Wang, D.Y.7
Li, Y.8
Wang, H.Y.9
Wang, R.-F.10
-
77
-
-
77955515616
-
Poly-ICLC promotes the infiltration of effector T cells into intracranial gliomas via induction of CXCL10 in IFN-alpha and IFN-gamma dependent manners
-
Zhu X, Fallert-Junecko BA, Fujita M, et al. Poly-ICLC promotes the infiltration of effector T cells into intracranial gliomas via induction of CXCL10 in IFN-alpha and IFN-gamma dependent manners. Cancer Immunol Immunother. 2010;59:1401-1409.
-
(2010)
Cancer Immunol Immunother
, vol.59
, pp. 1401-1409
-
-
Zhu, X.1
Fallert-Junecko, B.A.2
Fujita, M.3
-
78
-
-
77952540334
-
Monophosphoryl lipid A (MPL) as an adjuvant for anti-cancer vaccines: Clinical results
-
CluffCW. Monophosphoryl lipid A (MPL) as an adjuvant for anti-cancer vaccines: clinical results. Adv Exp Med Biol. 2010;667:111-123.
-
(2010)
Adv Exp Med Biol
, vol.667
, pp. 111-123
-
-
Cluff, C.W.1
-
79
-
-
42449147062
-
Enhanced efficacy and reduced toxicity of multifactorial adjuvants compared with unitary adjuvants as cancer vaccines
-
Ahonen CL, Wasiuk A, Fuse S, et al. Enhanced efficacy and reduced toxicity of multifactorial adjuvants compared with unitary adjuvants as cancer vaccines. Blood. 2008;111:3116-3125.
-
(2008)
Blood
, vol.111
, pp. 3116-3125
-
-
Ahonen, C.L.1
Wasiuk, A.2
Fuse, S.3
-
80
-
-
0029935569
-
Enhanced tumor outgrowth after peptide vaccination: Functional deletion of tumor-specific CTL induced by peptide vaccination can lead to the inability to reject tumors
-
Toes RE, Blom RJ, Offringa R, et al. Enhanced tumor outgrowth after peptide vaccination. Functional deletion of tumor-specific CTL induced by peptide vaccination can lead to the inability to reject tumors. J Immunol. 1996;156:3911-3918. (Pubitemid 26139943)
-
(1996)
Journal of Immunology
, vol.156
, Issue.10
, pp. 3911-3918
-
-
Toes, R.E.M.1
Blom, R.J.J.2
Offringa, R.3
Kast, W.M.4
Melief, C.J.M.5
-
81
-
-
0029798058
-
Peptide vaccination can lead to enhanced tumor growth through specific T-cell tolerance induction
-
DOI 10.1073/pnas.93.15.7855
-
Toes RE, Offringa R, Blom RJ, et al. Peptide vaccination can lead to enhanced tumor growth through specific T-cell tolerance induction. Proc Natl Acad Sci U S A. 1996;93:7855-7860. (Pubitemid 26277128)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.15
, pp. 7855-7860
-
-
Toes, R.E.M.1
Offringa, R.2
Blom, R.J.J.3
Melief, C.J.M.4
Kast, W.M.5
-
82
-
-
0027520754
-
Peptides of 23 residues or greater are required to stimulate a high affinity class II-restricted T cell response
-
Srinivasan M, Domanico SZ, Kaumaya PT, et al. Peptides of 23 residues or greater are required to stimulate a high affinity class-restricted T cell response. Eur J Immunol. 1993;23:1011-1016. (Pubitemid 23120158)
-
(1993)
European Journal of Immunology
, vol.23
, Issue.5
, pp. 1011-1016
-
-
Srinivasan, M.1
Domanico, S.Z.2
Kaumaya, P.T.P.3
Pierce, S.K.4
-
83
-
-
0036644556
-
Established human papillomavirus type 16-expressing tumors are effectively eradicated following vaccination with long peptides
-
Zwaveling S, Ferreira Mota SC, Nouta J, et al. Established human papillomavirus type 16Yexpressing tumors are effectively eradicated following vaccination with long peptides. J Immunol. 2002;169:350-358. (Pubitemid 34686155)
-
(2002)
Journal of Immunology
, vol.169
, Issue.1
, pp. 350-358
-
-
Zwaveling, S.1
Ferreira Mota, S.C.2
Nouta, J.3
Johnson, M.4
Lipford, G.B.5
Offringa, R.6
Van Der Burg, S.H.7
Melief, C.J.M.8
-
84
-
-
0141832121
-
MHC-guided processing: Binding of large antigen fragments
-
Sercarz EE, Maverakis E. MHC-guided processing: binding of large antigen fragments. Nat Rev Immunol. 2003;3:621-629. (Pubitemid 37328665)
-
(2003)
Nature Reviews Immunology
, vol.3
, Issue.8
, pp. 621-629
-
-
Sercarz, E.E.1
Maverakis, E.2
-
85
-
-
44849109375
-
Superior induction of antitumor CTL immunity by extended peptide vaccines involves prolonged, DC-focused antigen presentation
-
BijkerMS, van den Eeden SJ, FrankenKL, et al. Superior induction of antitumor CTL immunity by extended peptide vaccines involves prolonged, DC-focused antigen presentation. Eur J Immunol. 2008;38:1033-1042.
-
(2008)
Eur J Immunol
, vol.38
, pp. 1033-1042
-
-
Bijker, M.S.1
Van Den Eeden, S.J.2
Franken, K.L.3
-
86
-
-
14544288632
-
+ T-cell memory via TRAIL-mediated activation-induced cell death
-
DOI 10.1038/nature03337
-
Janssen EM, Droin NM, Lemmens EE, et al. CD4+ T cell help helps control CD8+ T-cell memory via TRAIL-mediated activation-induced cell death. Nature. 2010;434:88-93. (Pubitemid 40349390)
-
(2005)
Nature
, vol.434
, Issue.7029
, pp. 88-93
-
-
Janssen, E.M.1
Droin, N.M.2
Lemmens, E.E.3
Pinkoski, M.J.4
Bensinger, S.J.5
Ehst, B.D.6
Griffith, T.S.7
Green, D.R.8
Schoenberger, S.P.9
-
87
-
-
70350772293
-
Vaccination against HPV-16 oncoproteins for vulvar intraepithelial neoplasia
-
Kenter GG, Welters MJ, Valentijn AR, et al. Vaccination against HPV-16 oncoproteins for vulvar intraepithelial neoplasia. N Engl J Med. 2009;361:1838-1847.
-
(2009)
N Engl J Med
, vol.361
, pp. 1838-1847
-
-
Kenter, G.G.1
Welters, M.J.2
Valentijn, A.R.3
-
88
-
-
80053341541
-
-
National Cancer Institute Immunotherapy Agent Workshop. Bethesda, MD. 12 July 2007
-
National Cancer Institute Immunotherapy Agent Workshop. Bethesda, MD. 12 July 2007.
-
-
-
-
89
-
-
77954899030
-
Phase i study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: Safety, clinical activity, pharmacodynamics, and immunologic correlates
-
Brahmer JR, Drake CG, Wollner I, et al. Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates. J Clin Oncol. 2010;28:3167-3175.
-
(2010)
J Clin Oncol
, vol.28
, pp. 3167-3175
-
-
Brahmer, J.R.1
Drake, C.G.2
Wollner, I.3
-
90
-
-
77955917121
-
Safety and antitumor activity of biweekly MDX-1106 (Anti-PD-1, BMS-936558/ONO-4538) in patients with advanced refractory malignancies
-
Abstract 2506
-
Sznol M, Powderly JD, Smith DC, et al. Safety and antitumor activity of biweekly MDX-1106 (Anti-PD-1, BMS-936558/ONO-4538) in patients with advanced refractory malignancies. J Clin Oncol. 2010;28. Abstract 2506.
-
(2010)
J Clin Oncol
, pp. 28
-
-
Sznol, M.1
Powderly, J.D.2
Smith, D.C.3
-
91
-
-
79251571760
-
The role of the PD-1 pathway in autoimmunity and peripheral tolerance
-
Fife BT, Pauken KE. The role of the PD-1 pathway in autoimmunity and peripheral tolerance. Ann N Y Acad Sci. 2011;1217:45-59.
-
(2011)
Ann N y Acad Sci
, vol.1217
, pp. 45-59
-
-
Fife, B.T.1
Pauken, K.E.2
-
92
-
-
32544459770
-
Restoring function in exhausted CD8 T cells during chronic viral infection
-
DOI 10.1038/nature04444, PII NATURE04444
-
Barber DL,Wherry EJ, Masopust D, et al. Restoring function in exhausted CD8 T cells during chronic viral infection. Nature. 2006;439:682-687. (Pubitemid 43237609)
-
(2006)
Nature
, vol.439
, Issue.7077
, pp. 682-687
-
-
Barber, D.L.1
Wherry, E.J.2
Masopust, D.3
Zhu, B.4
Allison, J.P.5
Sharpe, A.H.6
Freeman, G.J.7
Ahmed, R.8
-
93
-
-
0037438490
-
Program death-1 engagement upon TCR activation has distinct effects on costimulation and cytokine-driven proliferation: Attenuation of ICOS, IL-4, and IL-21, but not CD28, IL-7, and IL-15 responses
-
Bennett F, Luxenberg D, Ling V, et al. Program death-1 engagement upon TCR activation has distinct effects on costimulation and cytokinedriven proliferation: attenuation of ICOS, IL-4, and IL-21, but not CD28, IL-7, and IL-15 responses. J Immunol. 2003;170:711-718. (Pubitemid 36070520)
-
(2003)
Journal of Immunology
, vol.170
, Issue.2
, pp. 711-718
-
-
Bennett, F.1
Luxenberg, D.2
Ling, V.3
Wang, I.-M.4
Marquette, K.5
Lowe, D.6
Khan, N.7
Veldman, G.8
Jacobs, K.A.9
Valge-Archer, V.E.10
Collins, M.11
Carreno, B.M.12
-
94
-
-
70350433514
-
Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal
-
Fife BT, Pauken KE, Eagar TN, et al. Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal. Nat Immunol. 2009;10:1185-1192.
-
(2009)
Nat Immunol
, vol.10
, pp. 1185-1192
-
-
Fife, B.T.1
Pauken, K.E.2
Eagar, T.N.3
-
95
-
-
13544259967
-
Prevention of experimental autoimmune encephalomyelitis by transfer of embryonic stem cell-derived dendritic cells expressing myelin oligodendrocyte glycoprotein peptide along with TRAIL or programmed death-1 ligand 1
-
Hirata S, Senju S, Matsuyoshi H, et al. Prevention of experimental autoimmune encephalomyelitis by transfer of embryonic stem cell-derived dendritic cells expressing myelin oligodendrocyte glycoprotein peptide along with TRAIL or programmed death-1 ligand. J Immunol. 2005;174:1888-1897. (Pubitemid 40223928)
-
(2005)
Journal of Immunology
, vol.174
, Issue.4
, pp. 1888-1897
-
-
Hirata, S.1
Senju, S.2
Matsuyoshi, H.3
Fukuma, D.4
Uemura, Y.5
Nishimura, Y.6
-
96
-
-
33751552197
-
Insulin-induced remission in new-onset NOD mice is maintained by the PD-1-PD-L1 pathway
-
DOI 10.1084/jem.20061577
-
Fife BT, Guleria I, Gubbels BM, et al. Insulin-induced remission in new-onset NOD mice is maintained by the PD-1YPD-L1 pathway. J Exp Med. 2006;203:2737-2747. (Pubitemid 44833349)
-
(2006)
Journal of Experimental Medicine
, vol.203
, Issue.12
, pp. 2737-2747
-
-
Fife, B.T.1
Guleria, I.2
Bupp, M.G.3
Eagar, T.N.4
Tang, Q.5
Bour-Jordan, H.6
Yagita, H.7
Azuma, M.8
Sayegh, M.H.9
Bluestone, J.A.10
-
97
-
-
68549135290
-
Integrated data from 2 randomized, double-blind, placebo-controlled, phase 3 trials of active cellular immunotherapy with Sipuleucel-T in advanced prostate cancer
-
Higano CS, Schellhammmer PF, Small EJ, et al. Integrated data from 2 randomized, double-blind, placebo-controlled, phase 3 trials of active cellular immunotherapy with Sipuleucel-T in advanced prostate cancer. Cancer. 2009;115:3670-3679.
-
(2009)
Cancer
, vol.115
, pp. 3670-3679
-
-
Higano, C.S.1
Schellhammmer, P.F.2
Small, E.J.3
-
98
-
-
70350135349
-
A phase III multiinstitutional randomized study of immunization with the gp100: 209-217(210M) peptide followed by high-dose IL-2 compared with high-dose IL-2 alone in patients with metastatic melanoma
-
Abstract CRA9011
-
Schwartzentruber DJ, Lawson D, Richards J, et al. A phase III multiinstitutional randomized study of immunization with the gp100: 209-217(210M) peptide followed by high-dose IL-2 compared with high-dose IL-2 alone in patients with metastatic melanoma. J Clin Oncol. 2009;27. Abstract CRA9011.
-
(2009)
J Clin Oncol
, pp. 27
-
-
Schwartzentruber, D.J.1
Lawson, D.2
Richards, J.3
-
99
-
-
79957831345
-
Gp100 peptide vaccine and interleukin-2 in patients with advanced melanoma
-
Schwartzentruber DJ, Lawson DH, Richards JM, et al. gp100 peptide vaccine and interleukin-2 in patients with advanced melanoma. N Engl J Med. 2011;364:2119-2127.
-
(2011)
N Engl J Med
, vol.364
, pp. 2119-2127
-
-
Schwartzentruber, D.J.1
Lawson, D.H.2
Richards, J.M.3
-
100
-
-
72549086588
-
Effect of granulocyte/macrophage colony-stimulating factor on vaccination with an allogeneic whole-cell melanoma vaccine
-
Faries MB, Hsueh EC, Ye X, et al. Effect of granulocyte/macrophage colony-stimulating factor on vaccination with an allogeneic whole-cell melanoma vaccine. Clin Cancer Res. 2009;15:7029-7035.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 7029-7035
-
-
Faries, M.B.1
Hsueh, E.C.2
Ye, X.3
-
101
-
-
78449242173
-
E4697: Phase III cooperative group study of yeast-derived granulocyte macrophage colony-stimulating factor (GM-CSF) versus placebo as adjuvant treatment of patients with completely resected stage III-IV melanoma
-
Abstract 8504
-
Lawson DH, Lee SJ, Tarhini AA, et al. E4697: phase III cooperative group study of yeast-derived granulocyte macrophage colony-stimulating factor (GM-CSF) versus placebo as adjuvant treatment of patients with completely resected stage III-IV melanoma. J Clin Oncol. 2010;28. Abstract 8504.
-
(2010)
J Clin Oncol.
, pp. 28
-
-
Lawson, D.H.1
Lee, S.J.2
Tarhini, A.A.3
|