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Volumn 186, Issue 5, 1997, Pages 645-653

Self antigens expressed by solid tumors do not efficiently stimulate naive or activated T cells: Implications for immunotherapy

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; INSULIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; TUMOR ANTIGEN; VIRUS GLYCOPROTEIN; VIRUS T ANTIGEN;

EID: 0030848578     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.186.5.645     Document Type: Article
Times cited : (282)

References (43)
  • 3
    • 0029310528 scopus 로고
    • T-cell immunotherapy of tumors by adoptive transfer of cytotoxic T lymphocytes and by vaccination with minimal essential epitopes
    • Melief, C.J.M., and W.M. Kast. 1994. T-cell immunotherapy of tumors by adoptive transfer of cytotoxic T lymphocytes and by vaccination with minimal essential epitopes. Immunol. Rev. 145:167-177.
    • (1994) Immunol. Rev. , vol.145 , pp. 167-177
    • Melief, C.J.M.1    Kast, W.M.2
  • 4
    • 0029310484 scopus 로고
    • Can costimulated tumor immunity be therapeutically efficacious?
    • Hellström, K.E., I. Hellström, and L. Chen. 1994. Can costimulated tumor immunity be therapeutically efficacious? Immunol. Rev. 145:123-145.
    • (1994) Immunol. Rev. , vol.145 , pp. 123-145
    • Hellström, K.E.1    Hellström, I.2    Chen, L.3
  • 5
    • 0027940415 scopus 로고
    • Tumor immunotherapy: The tumor cell as an antigen-presenting cell
    • Ostrand-Rosenberg, S. 1994. Tumor immunotherapy: the tumor cell as an antigen-presenting cell. Curr. Opin. Immunol. 6:722-727.
    • (1994) Curr. Opin. Immunol. , vol.6 , pp. 722-727
    • Ostrand-Rosenberg, S.1
  • 6
    • 0028298062 scopus 로고
    • Timely immunization subverts the development of peripheral nonresponsiveness and suppresses tumor development in simian virus 40 tumor antigen-transgenic mice
    • Ye, X., J. McCarrick, L. Jewett, and B.B. Knowles. 1994. Timely immunization subverts the development of peripheral nonresponsiveness and suppresses tumor development in simian virus 40 tumor antigen-transgenic mice. Proc. Natl. Acad. Sci. USA. 91:3916-3920.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 3916-3920
    • Ye, X.1    McCarrick, J.2    Jewett, L.3    Knowles, B.B.4
  • 8
    • 0028691781 scopus 로고
    • Neoplastic cells that express low levels of MHC class I determinants escape host immunity
    • Cohen, E.P., and T.S. Kim. 1994. Neoplastic cells that express low levels of MHC class I determinants escape host immunity. Semin. Cancer Biol. 5:419-428.
    • (1994) Semin. Cancer Biol. , vol.5 , pp. 419-428
    • Cohen, E.P.1    Kim, T.S.2
  • 10
    • 0030065569 scopus 로고    scopus 로고
    • Modulation of L-selectin ligand expression during an immune response accompanying tumorigenesis in transgenic mice
    • Onrust, S.V., P.M. Hartl, S.D. Rosen, and D. Hanahan. 1996. Modulation of L-selectin ligand expression during an immune response accompanying tumorigenesis in transgenic mice. J. Clin. Invest. 97:54-64.
    • (1996) J. Clin. Invest. , vol.97 , pp. 54-64
    • Onrust, S.V.1    Hartl, P.M.2    Rosen, S.D.3    Hanahan, D.4
  • 11
    • 0017333054 scopus 로고
    • Rejection by syngeneic mice of cell variants obtained by mutagenesis of a malignant teratocarcinoma cell line
    • Boon, T., and O. Kellermann. 1977. Rejection by syngeneic mice of cell variants obtained by mutagenesis of a malignant teratocarcinoma cell line. Proc. Natl. Acad. Sci. USA. 74:272-275.
    • (1977) Proc. Natl. Acad. Sci. USA , vol.74 , pp. 272-275
    • Boon, T.1    Kellermann, O.2
  • 12
    • 0018192352 scopus 로고
    • Teratocarcinoma cell variants rejected by syngeneic mice: Protection of mice immunized with these variants against other variants and against the original malignant cell line
    • Boon, T., and A. Van Pel. 1978. Teratocarcinoma cell variants rejected by syngeneic mice: protection of mice immunized with these variants against other variants and against the original malignant cell line. Proc. Natl. Acad. Sci. USA. 75: 1519-1523.
    • (1978) Proc. Natl. Acad. Sci. USA , vol.75 , pp. 1519-1523
    • Boon, T.1    Van Pel, A.2
  • 13
    • 0027078670 scopus 로고
    • Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4
    • Chen, L., S. Ashe, W.A. Brady, I. Hellström, K.E. Hellström, J.A. Ledbetter, P. McGowan, and P.S. Linsley. 1992. Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4. Cell. 71:1093-1102.
    • (1992) Cell , vol.71 , pp. 1093-1102
    • Chen, L.1    Ashe, S.2    Brady, W.A.3    Hellström, I.4    Hellström, K.E.5    Ledbetter, J.A.6    McGowan, P.7    Linsley, P.S.8
  • 15
    • 0029864363 scopus 로고    scopus 로고
    • Does B7-1 expression confer antigen-presenting cell capacity to tumors in vivo?
    • Huang, A.Y.C., A.T. Bruce, D.M. Pardoll, and H.I. Levitsky. 1996. Does B7-1 expression confer antigen-presenting cell capacity to tumors in vivo? J. Exp. Med. 183:769-776.
    • (1996) J. Exp. Med. , vol.183 , pp. 769-776
    • Huang, A.Y.C.1    Bruce, A.T.2    Pardoll, D.M.3    Levitsky, H.I.4
  • 16
    • 0029060005 scopus 로고
    • Limited capacity for tolerization of CD4+ T cells specific for a pancreatic β cell neo-antigen
    • Förster, I., R. Hirose, J.M. Arbeit, B.E. Clausen, and D. Hanahan. 1995. Limited capacity for tolerization of CD4+ T cells specific for a pancreatic β cell neo-antigen. Immunity. 2:573-585.
    • (1995) Immunity , vol.2 , pp. 573-585
    • Förster, I.1    Hirose, R.2    Arbeit, J.M.3    Clausen, B.E.4    Hanahan, D.5
  • 17
    • 0028298224 scopus 로고
    • Cancer antigens: Immune recognition of self and altered self
    • Houghton, A.N. 1994. Cancer antigens: immune recognition of self and altered self. J. Exp. Med. 180:1-4.
    • (1994) J. Exp. Med. , vol.180 , pp. 1-4
    • Houghton, A.N.1
  • 18
    • 0029055849 scopus 로고
    • Induction of anti-self-immunity to cure cancer
    • Nanda, N.K., and E.E. Sercarz. 1995. Induction of anti-self-immunity to cure cancer. Cell. 82:13-17.
    • (1995) Cell , vol.82 , pp. 13-17
    • Nanda, N.K.1    Sercarz, E.E.2
  • 20
    • 0026690684 scopus 로고
    • Functional analysis of the retinoblastoma gene product and of RB-SV40 T antigen complexes
    • A.J. Levine and L.M. Franks, editors. Imperial Cancer Research Fund, Cold Spring Harbor, NY
    • Livingston, D.M. 1992. Functional analysis of the retinoblastoma gene product and of RB-SV40 T antigen complexes. In Tumor Suppressor Genes, the Cell Cycle and Cancer. A.J. Levine and L.M. Franks, editors. Imperial Cancer Research Fund, Cold Spring Harbor, NY. 153-160.
    • (1992) Tumor Suppressor Genes, the Cell Cycle and Cancer , pp. 153-160
    • Livingston, D.M.1
  • 21
    • 0027218350 scopus 로고
    • Interactions between SV40 large-tumor antigen and the growth suppressor proteins pRB and p53
    • Ludlow, J.W. 1993. Interactions between SV40 large-tumor antigen and the growth suppressor proteins pRB and p53. FASEB (Fed. Am. Soc. Exp. Biol.) J. 7:866-871.
    • (1993) FASEB (Fed. Am. Soc. Exp. Biol.) J. , vol.7 , pp. 866-871
    • Ludlow, J.W.1
  • 22
    • 0021888904 scopus 로고
    • Heritable formation of pancreatic β-cell tumours in transgenic mice expressing recombinant insulin/ simian virus 40 oncogenes
    • Hanahan, D. 1985. Heritable formation of pancreatic β-cell tumours in transgenic mice expressing recombinant insulin/ simian virus 40 oncogenes. Nature (Lond.). 315:115-122.
    • (1985) Nature (Lond.) , vol.315 , pp. 115-122
    • Hanahan, D.1
  • 23
    • 0023108381 scopus 로고
    • Non-tolerance and autoantibodies to a transgenic self antigen expressed in pancreatic β cells
    • Adams, T.E., S. Alpert, and D. Hanahan. 1987. Non-tolerance and autoantibodies to a transgenic self antigen expressed in pancreatic β cells. Nature (Lond.). 325:223-228.
    • (1987) Nature (Lond.) , vol.325 , pp. 223-228
    • Adams, T.E.1    Alpert, S.2    Hanahan, D.3
  • 25
    • 0002046199 scopus 로고
    • Lymphocytic choriomeningitis virus
    • Lehmann-Grube, F. 1971. Lymphocytic choriomeningitis virus. Virol. Monogr. 10:1-173.
    • (1971) Virol. Monogr. , vol.10 , pp. 1-173
    • Lehmann-Grube, F.1
  • 26
    • 0023255757 scopus 로고
    • The immune response of the mouse to lymphocytic choriomeningitis virus. V. High numbers of cytolytic T lymphocytes are generated in the spleen during acute infection
    • Moskophidis, D., U. Assmann-Wischer, M.M. Simon, and F. Lehmann-Grube. 1987. The immune response of the mouse to lymphocytic choriomeningitis virus. V. High numbers of cytolytic T lymphocytes are generated in the spleen during acute infection. Eur. J. Immunol. 17:937-942.
    • (1987) Eur. J. Immunol. , vol.17 , pp. 937-942
    • Moskophidis, D.1    Assmann-Wischer, U.2    Simon, M.M.3    Lehmann-Grube, F.4
  • 27
    • 0024307348 scopus 로고
    • Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen
    • Pircher, H., K. Bürki, R. Lang, H. Hengartner, and R. Zinkernagel. 1989. Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen. Nature (Lond.). 342:559-561.
    • (1989) Nature (Lond.) , vol.342 , pp. 559-561
    • Pircher, H.1    Bürki, K.2    Lang, R.3    Hengartner, H.4    Zinkernagel, R.5
  • 28
    • 0000223410 scopus 로고
    • Cell-surface differentiation in the mouse
    • R.H. Kennett, T.J. McKearn, and K.B. Bechtol, editors. Plenum Press, New York
    • Springer, T.A. 1980. Cell-surface differentiation in the mouse. In Monoclonal Antibodies. R.H. Kennett, T.J. McKearn, and K.B. Bechtol, editors. Plenum Press, New York. 185-217.
    • (1980) Monoclonal Antibodies , pp. 185-217
    • Springer, T.A.1
  • 29
    • 0021723276 scopus 로고
    • Therapy with monoclonal antibodies by elimination of T cell subsets in vivo
    • Cobbold, S.P., A. Jayasuriya, A. Nash, T.D. Prospero, and H. Waldmann. 1984. Therapy with monoclonal antibodies by elimination of T cell subsets in vivo. Nature (Lond.). 312:548-551.
    • (1984) Nature (Lond.) , vol.312 , pp. 548-551
    • Cobbold, S.P.1    Jayasuriya, A.2    Nash, A.3    Prospero, T.D.4    Waldmann, H.5
  • 30
    • 0025114152 scopus 로고
    • Vaccination and protection from a lethal viral infection: Identification, incorporation, and use of a cytotoxic T lymphocyte glycoprotein epitope
    • Klavinskis, L.S., J.L. Whitton, E. Joly, and M.B.A. Oldstone. 1990. Vaccination and protection from a lethal viral infection: identification, incorporation, and use of a cytotoxic T lymphocyte glycoprotein epitope. Virology. 178:393-400.
    • (1990) Virology , vol.178 , pp. 393-400
    • Klavinskis, L.S.1    Whitton, J.L.2    Joly, E.3    Oldstone, M.B.A.4
  • 31
    • 0028446546 scopus 로고
    • How virus induces a rapid or slow onset insulin-dependent diabetes mellitus in a transgenic model
    • von Herrath, M.G., J. Dockter, and M.B.A. Oldstone. 1994. How virus induces a rapid or slow onset insulin-dependent diabetes mellitus in a transgenic model. Immunity. 1:231-242.
    • (1994) Immunity , vol.1 , pp. 231-242
    • Von Herrath, M.G.1    Dockter, J.2    Oldstone, M.B.A.3
  • 32
    • 70449193189 scopus 로고
    • Immunity to methylcholanthrene-induced sarcomas
    • Prehn, R.T., and J.M. Main. 1957. Immunity to methylcholanthrene-induced sarcomas. J. Natl. Cancer Inst. 18:769-782.
    • (1957) J. Natl. Cancer Inst. , vol.18 , pp. 769-782
    • Prehn, R.T.1    Main, J.M.2
  • 33
    • 0000727852 scopus 로고
    • Antigenic properties of lymphomas induced by the Moloney agent
    • Klein, E., and G. Klein. 1964. Antigenic properties of lymphomas induced by the Moloney agent. J. Natl. Cancer Inst. 32:547-565.
    • (1964) J. Natl. Cancer Inst. , vol.32 , pp. 547-565
    • Klein, E.1    Klein, G.2
  • 34
    • 0016173689 scopus 로고
    • Antigenicity of murine skin tumors induced by ultraviolet light
    • Kripke, M.L. 1974. Antigenicity of murine skin tumors induced by ultraviolet light. J. Natl. Cancer Inst. 53:1333-1336.
    • (1974) J. Natl. Cancer Inst. , vol.53 , pp. 1333-1336
    • Kripke, M.L.1
  • 35
    • 0025923312 scopus 로고
    • T and B cell tolerance and responses to viral antigens in transgenic mice: Implications for the pathogenesis of autoimmune versus immunopathological disease
    • Zinkernagel, R.M., H. Pircher, P.S. Ohashi, S. Oehen, B. Odermatt, T.W. Mak, H. Arnheiter, K. Bürki, and H. Hengartner. 1991. T and B cell tolerance and responses to viral antigens in transgenic mice: implications for the pathogenesis of autoimmune versus immunopathological disease. Immunol. Rev. 122:133-171.
    • (1991) Immunol. Rev. , vol.122 , pp. 133-171
    • Zinkernagel, R.M.1    Pircher, H.2    Ohashi, P.S.3    Oehen, S.4    Odermatt, B.5    Mak, T.W.6    Arnheiter, H.7    Bürki, K.8    Hengartner, H.9
  • 37
    • 0020561143 scopus 로고
    • Autoantibodies to normal human melanocytes in vitiligo
    • Naughton, G.K., M. Eisinger, and J.C. Bystryn. 1983. Autoantibodies to normal human melanocytes in vitiligo. J. Exp. Med. 158:246-251.
    • (1983) J. Exp. Med. , vol.158 , pp. 246-251
    • Naughton, G.K.1    Eisinger, M.2    Bystryn, J.C.3
  • 42
    • 0028786994 scopus 로고
    • Implicating a role for immune recognition of self in tumor rejection: Immunization against the brown locus protein
    • Hara, I., Y. Takechi, and A.N. Houghton. 1995. Implicating a role for immune recognition of self in tumor rejection: immunization against the brown locus protein. J. Exp. Med. 182:1609-1614.
    • (1995) J. Exp. Med. , vol.182 , pp. 1609-1614
    • Hara, I.1    Takechi, Y.2    Houghton, A.N.3
  • 43
    • 0027190467 scopus 로고
    • An evaluation of the potential to use tumor-associated antigens as targets for antitumor T cell therapy using transgenic mice expressing a retroviral tumor antigen in normal lymphoid tissues
    • Hu, J., W. Kindsvogel, S. Busby, M.C. Bailey, Y.Y. Shi, and P.D. Greenberg. 1993. An evaluation of the potential to use tumor-associated antigens as targets for antitumor T cell therapy using transgenic mice expressing a retroviral tumor antigen in normal lymphoid tissues. J. Exp. Med. 177:1681-1690.
    • (1993) J. Exp. Med. , vol.177 , pp. 1681-1690
    • Hu, J.1    Kindsvogel, W.2    Busby, S.3    Bailey, M.C.4    Shi, Y.Y.5    Greenberg, P.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.